Periodontal treatment decreases levels of antibodies to porphyromonas gingivalis and citrulline in patients with rheumatoid arthritis and periodontitis

Journal of Periodontology

Volumn 84, Issue 12, 2013, Pages

  Okada, Moe ^a   Kobayashi, Tetsuo ^a,b   Ito, Satoshi ^c   Yokoyama, Tomoko ^a   Abe, Asami ^c   Murasawa, Akira ^c   Yoshie, Hiromasa ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b NIIGATA UNIVERSITY MEDICAL AND DENTAL HOSPITAL   (Japan)

^c Niigata Rheumatic Center   (Japan)

Author keywords

Amino acids; Antibody formation; Arthritis, rheumatoid; Periodontitis; Porphyromonas gingivalis; Therapy

Indexed keywords

BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; C REACTIVE PROTEIN; CARRIER PROTEIN; CITRULLINE; HEME BINDING PROTEIN; HEME-BINDING PROTEIN; HEMOPROTEIN; IMMUNOGLOBULIN G; INTERLEUKIN 6; MMP3 PROTEIN, HUMAN; RHEUMATOID FACTOR; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; BLOOD; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EDUCATION; FEMALE; FOLLOW UP; HUMAN; IMMUNOLOGY; MALE; METHODOLOGY; MICROBIOLOGY; MIDDLE AGED; MOUTH HYGIENE; PERIODONTAL DISEASE; PERIODONTAL POCKET; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; PREVENTIVE DENTISTRY; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; ARTHRITIS, RHEUMATOID; C-REACTIVE PROTEIN; CARRIER PROTEINS; CITRULLINE; DENTAL SCALING; FEMALE; FOLLOW-UP STUDIES; HEMEPROTEINS; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-6; MALE; MATRIX METALLOPROTEINASE 3; MIDDLE AGED; ORAL HYGIENE; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL POCKET; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; RHEUMATOID FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84890250063     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2013.130079     Document Type: Article

References (47)

1. Ka?sser UR, Gleissner C, Dehne F, Michel A, Willershausen- Zo?nnchen B, Bolten WW. Risk for periodontal disease in patients with longstanding rheumatoid arthritis. Arthritis Rheum 1997;40:2248-2251.
2. Gleissner C, Willershausen B, Kaesser U, Bolten WW. The role of risk factors for periodontal disease in patients with rheumatoid arthritis. Eur J Med Res 1998; 3:387-392.
3. Mercado FB, Marshall RI, Bartold PM. Inter-Relationships between rheumatoid arthritis and periodontal disease. A review. J Clin Periodontol 2003;30:761-772.
4. Havemose-Poulsen A, Westergaard J, Stoltze K, et al. Periodontal and hematological characteristics associated with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis. J Periodontol 2006; 77:280-288.
5. Pischon N, Pischon T, Kro?ger J, et al. Association among rheumatoid arthritis, oral hygiene, and periodontitis. J Periodontol 2008;79:979-986.
6. Dissick A, Redman RS, Jones M, et al. Association of periodontitis with rheumatoid arthritis: A pilot study. J Periodontol 2010;81:223-230.
7. Moen K, Brun JG, Madland TM, Tynning T, Jonsson R. Immunoglobulin G and A antibody responses to Bacteroides forsythus and Prevotella intermedia in sera and synovial fluids of arthritis patients. Clin Diagn Lab Immunol 2003;10:1043-1050.
8. Ogrendik M, Kokino S, Ozdemir F, Bird PS, Hamlet S. Serum antibodies to oral anaerobic bacteria in patients with rheumatoid arthritis. MedGenMed 2005;7:2.
9. Pischon N, Ro?hner E, Hocke A, et al. Effects of Porphyromonas gingivalis on cell cycle progression and apoptosis of primary human chondrocytes. Ann Rheum Dis 2009;68:1902-1907.
10. Ro?hner E, Detert J, Kolar P, et al. Induced apoptosis of chondrocytes by Porphyromonas gingivalis as a possible pathway for cartilage loss in rheumatoid arthritis. Calcif Tissue Int 2010;87:333-340.
11. Bartold PM, Marino V, Cantley M, Haynes DR. Effect of Porphyromonas gingivalis-Induced inflammation on the development of rheumatoid arthritis. J Clin Periodontol 2010;37:405-411.
12. McGraw WT, Potempa J, Farley D, Travis J. Purification, characterization, and sequence analysis of a potential virulence factor from Porphyromonas gingivalis, peptidylarginine deiminase. Infect Immun 1999;67: 3248-3256.
13. Wegner N, Wait R, Sroka A, et al. Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and a-Enolase: Implications for autoimmunity in rheumatoid arthritis. Arthritis Rheum 2010;62:2662-2672.
14. Al-Shukaili A, Al-Ghafri S, Al-Marhooni S, Alkaabi J. Evaluation of anti-Mutated citrullinated vimentin antibodies, anti-Cyclic citrullinated peptide antibodies and rheumatoid factor in Omani patients with rheumatoid arthritis. Int J Rheumatol 2012;2012:285854.
15. Okada M, Kobayashi T, Ito S, et al. Antibody responses to periodontopathic bacteria in relation to rheumatoid arthritis in Japanese adults. J Periodontol 2011;82: 1433-1441.
16. Mikuls TR, Payne JB, Reinhardt RA, et al. Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis. Int Immunopharmacol 2009;9:38-42.
17. Hitchon CA, Chandad F, Ferucci ED, et al. Antibodies to Porphyromonas gingivalis are associated with anticitrullinated protein antibodies in patients with rheumatoid arthritis and their relatives. J Rheumatol 2010;37:1105-1112.
18. Mikuls TR, Thiele GM, Deane KD, et al. Porphyromonas gingivalis and disease-Related autoantibodies in individuals at increased risk of rheumatoid arthritis. Arthritis Rheum 2012;64:3522-3530.
19. Ribeiro J, Lea?o A, Novaes AB. Periodontal infection as a possible severity factor for rheumatoid arthritis. J Clin Periodontol 2005;32:412-416.
20. Al-Katma MK, Bissada NF, Bordeaux JM, Sue J, Askari AD. Control of periodontal infection reduces the severity of active rheumatoid arthritis. J Clin Rheumatol 2007;13:134-137.
21. Ortiz P, Bissada NF, Palomo L, et al. Periodontal therapy reduces the severity of active rheumatoid arthritis in patients treated with or without tumor necrosis factor inhibitors. J Periodontol 2009;80:535- 540.
22. Erciyas K, Sezer U, Ustu?n K, et al. Effects of periodontal therapy on disease activity and systemic inflammation in rheumatoid arthritis patients. Oral Dis 2013;19:394-400.
23. Shibata Y, Okano S, Shiroza T, et al. Characterization of human-Type monoclonal antibodies against reduced form of hemin binding protein 35 from Porphyromonas gingivalis. J Periodontal Res 2011;46: 673-681.
24. Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-324.
25. Aletaha D, Neogi T, Silman AJ, et al. 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum 2010;62:2569-2581.
26. Lo?e H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963;21: 533-551.
27. Esen Cx, Alkan BA, K?rnap M, Akgu?l O?, Isx?ko-Glu S, Erel O? . The effects of chronic periodontitis and rheumatoid arthritis on serum and gingival crevicular fluid total antioxidant/oxidant status and oxidative stress index. J Periodontol 2012;83:773-779.
28. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1-6.
29. Inoue E, Yamanaka H, Hara M, Tomatsu T, Kamatani N. Comparison of Disease Activity Score (DAS)28- erythrocyte sedimentation rate and DAS28- C-Reactive protein threshold values. Ann Rheum Dis 2007;66: 407-409.
30. Shidara K, Inoue E, Tanaka E, et al. Comparison of the second and third generation anti-Cyclic citrullinated peptide antibody assays in the diagnosis of Japanese patients with rheumatoid arthritis. Rheumatol Int 2011;31:617-622.
31. Takeuchi-Hatanaka K, Ohyama H, Nishimura F, et al. Polymorphisms in the 59 flanking region of IL12RB2 are associated with susceptibility to periodontal diseases in the Japanese population. J Clin Periodontol 2008;35: 317-323.
32. Shimbo K, Kubo S, Harada Y, et al. Automated precolumn derivatization system for analyzing physiological amino acids by liquid chromatography/mass spectrometry. Biomed Chromatogr 2010;24: 683-691.
33. Wang D, Koshy G, Nagasawa T, et al. Antibody response after single-Visit full-Mouth ultrasonic debridement versus quadrant-Wise therapy. J Clin Periodontol 2006;33:632-638.
34. Horibe M, Watanabe H, Ishikawa I. Effect of periodontal treatments on serum IgG antibody titers against periodontopathic bacteria. J Clin Periodontol 1995;22:510-515.
35. Kudo C, Naruishi K, Maeda H, et al. Assessment of the plasma/serum IgG test to screen for periodontitis. J Dent Res 2012;91:1190-1195.
36. D'Aiuto F, Nibali L, Parkar M, Suvan J, Tonetti MS. Short-Term effects of intensive periodontal therapy on serum inflammatory markers and cholesterol. J Dent Res 2005;84:269-273.
37. Shimada Y,Komatsu Y, Ikezawa-Suzuki I, TaiH, SugitaN, Yoshie H. The effect of periodontal treatment on serum leptin, interleukin-6, and C-Reactive protein. J Periodontol 2010;81:1118-1123.
38. Been V, Engel D. The effects of immunosuppressive drugs on periodontal inflammation in human renal allograft patients. J Periodontol 1982;53:245-248.
39. Howell TH. Blocking periodontal disease progression with anti-Inflammatory agents. J Periodontol 1993;64 (Suppl. 8):828-833.
40. Kremer JM, Lee JK. The safety and efficacy of the use of methotrexate in long-Term therapy for rheumatoid arthritis. Arthritis Rheum 1986;29:822-831.
41. Hansen TM, Kryger P, Elling H, et al. Double blind placebo controlled trial of pulse treatment with methylprednisolone combined with disease modifying drugs in rheumatoid arthritis. BMJ 1990;301:268-270.
42. Tarp S, Bartels EM, Bliddal H, et al. Effect of nonsteroidal antiinflammatory drugs on the C-Reactive protein level in rheumatoid arthritis: A meta-Analysis of randomized controlled trials. Arthritis Rheum 2012;64:3511-3521.
43. Gargiulo AV Jr., Robinson J, Toto PD, Gargiulo AW. Identification of rheumatoid factor in periodontal disease. J Periodontol 1982;53:568-577.
44. Gargiulo AV Jr., Toto PD, Robinson JA, Gargiulo AW. Latex slide agglutination vs. ELISA system. Rheumatoid factor detection in inflamed human gingiva. J Periodontal Res 1985;20:31-34.
45. Thé J, Ebersole JL. Rheumatoid factor (RF) distribution in periodontal disease. J Clin Immunol 1991;11: 132-142.
46. Hara Y, Kaneko T, Yoshimura A, Kato I. Serum rheumatoid factor induced by intraperitoneal administration of periodontopathic bacterial lipopolysaccharide in mice. J Periodontal Res 1996;31: 502-507.
47. Naito Y, Okuda K, Takazoe I, Watanabe H, Ishikawa I. The relationship between serum IgG levels to subgingival gram-Negative bacteria and degree of periodontal destruction. J Dent Res 1985;64:1306-1310.