-
1
-
-
77953462904
-
Targeting the BCR-ABL tyrosine kinase in chronic myeloid leukemia as a model of rational drug design in cancer
-
Zámeníkova A. Targeting the BCR-ABL tyrosine kinase in chronic myeloid leukemia as a model of rational drug design in cancer. Expert Rev Hematol 2010;1:45-56.
-
(2010)
Expert Rev Hematol
, vol.1
, pp. 45-56
-
-
Zámeníkova, A.1
-
2
-
-
84877748707
-
Mechanisms responsible for nilotinib resistance in human chronic myeloid leukemia cells and reversal of resistance
-
Camgoz A, Gencer EB, Ural AU, Baran Y. Mechanisms responsible for nilotinib resistance in human chronic myeloid leukemia cells and reversal of resistance. Leuk Lymphoma 2013;54:1279-87.
-
(2013)
Leuk Lymphoma
, vol.54
, pp. 1279-1287
-
-
Camgoz, A.1
Gencer, E.B.2
Ural, A.U.3
Baran, Y.4
-
3
-
-
84864867324
-
Role of treatment in the appearance and selection of BCR-ABL1 kinase domain mutations
-
Razga F, Jurcek T, Zackova D, Dvorakova D, Toskova M, Jeziskova I, Mayer J, Racil Z. Role of treatment in the appearance and selection of BCR-ABL1 kinase domain mutations. Mol Diagn Ther 2012;16:251-9.
-
(2012)
Mol Diagn Ther
, vol.16
, pp. 251-259
-
-
Razga, F.1
Jurcek, T.2
Zackova, D.3
Dvorakova, D.4
Toskova, M.5
Jeziskova, I.6
Mayer, J.7
Racil, Z.8
-
4
-
-
80055002578
-
Tyrosine kinase inhibitor resistance in chronic myeloid leukemia cell lines: investigating resistance pathways
-
Tang C, Schafranek L, Watkins DB, Parker WT, Moore S, Prime JA, White DL, Hughes TP. Tyrosine kinase inhibitor resistance in chronic myeloid leukemia cell lines: investigating resistance pathways. Leuk Lymphoma 2011;52:2139-47.
-
(2011)
Leuk Lymphoma
, vol.52
, pp. 2139-2147
-
-
Tang, C.1
Schafranek, L.2
Watkins, D.B.3
Parker, W.T.4
Moore, S.5
Prime, J.A.6
White, D.L.7
Hughes, T.P.8
-
5
-
-
38349029112
-
Temporal patterns of association between cigarette smoking and leukemia risk
-
Richardson DB, Terschüren C, Pohlabeln H, Jöckel KH, Hoffmann W. Temporal patterns of association between cigarette smoking and leukemia risk. Cancer Causes Control 2008;19:43-50.
-
(2008)
Cancer Causes Control
, vol.19
, pp. 43-50
-
-
Richardson, D.B.1
Terschüren, C.2
Pohlabeln, H.3
Jöckel, K.H.4
Hoffmann, W.5
-
6
-
-
84864986621
-
Occupational benzene exposure and the risk of chronic myeloid leukemia: a meta-analysis of cohort studies incorporating study quality dimensions
-
Vlaanderen J, Lan Q, Kromhout H, Rothman N, Vermeulen R. Occupational benzene exposure and the risk of chronic myeloid leukemia: a meta-analysis of cohort studies incorporating study quality dimensions. Am J Ind Med 2012;55:779-85.
-
(2012)
Am J Ind Med
, vol.55
, pp. 779-785
-
-
Vlaanderen, J.1
Lan, Q.2
Kromhout, H.3
Rothman, N.4
Vermeulen, R.5
-
7
-
-
77951977494
-
Role of oxidatively induced DNA lesions in human pathogenesis
-
Sedelnikova OA, Redon CE, Dickey JS, Nakamura AJ, Georgakilas AG, Bonner WM. Role of oxidatively induced DNA lesions in human pathogenesis. Mutat Res 2010;704:152-9.
-
(2010)
Mutat Res
, vol.704
, pp. 152-159
-
-
Sedelnikova, O.A.1
Redon, C.E.2
Dickey, J.S.3
Nakamura, A.J.4
Georgakilas, A.G.5
Bonner, W.M.6
-
8
-
-
72649098994
-
Involvement of NAD(P)H:quinone oxidoreductase 1 and superoxide dismutase polymorphisms in ulcerative colitis
-
Kosaka T, Yoshino J, Inui K, et al. Involvement of NAD(P)H:quinone oxidoreductase 1 and superoxide dismutase polymorphisms in ulcerative colitis. DNA Cell Biol 2009;28:625-31.
-
(2009)
DNA Cell Biol
, vol.28
, pp. 625-631
-
-
Kosaka, T.1
Yoshino, J.2
Inui, K.3
-
9
-
-
68449083502
-
Overexpression of HO-1 protects against TNF-alpha-mediated airway inflammation by down-regulation of TNFR1-dependent oxidative stress
-
Lee IT, Luo SF, Lee CW, Wang SW, Lin CC, Chang CC, Chen YL, Chau LY, Yang CM. Overexpression of HO-1 protects against TNF-alpha-mediated airway inflammation by down-regulation of TNFR1-dependent oxidative stress. Am J Pathol 2009;175:519-32.
-
(2009)
Am J Pathol
, vol.175
, pp. 519-532
-
-
Lee, I.T.1
Luo, S.F.2
Lee, C.W.3
Wang, S.W.4
Lin, C.C.5
Chang, C.C.6
Chen, Y.L.7
Chau, L.Y.8
Yang, C.M.9
-
10
-
-
78149474811
-
Sulforaphane induces glutathione S-transferase isozymes which detoxify aflatoxin B(1)-8,9-epoxide in AML 12 cells
-
Gao SS, Chen XY, Zhu RZ, Choi BM, Kim BR. Sulforaphane induces glutathione S-transferase isozymes which detoxify aflatoxin B(1)-8, 9-epoxide in AML 12 cells. BioFactors 2010;36:289-96.
-
(2010)
BioFactors
, vol.36
, pp. 289-296
-
-
Gao, S.S.1
Chen, X.Y.2
Zhu, R.Z.3
Choi, B.M.4
Kim, B.R.5
-
11
-
-
13544252575
-
The effect of UDP-glucuronosyltransferase 1A1 expression on the mutagenicity and metabolism of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in CHO cells
-
Malfatti MA, Wu RW, Felton JS. The effect of UDP-glucuronosyltransferase 1A1 expression on the mutagenicity and metabolism of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine in CHO cells. Mutat Res 2005;570:205-14.
-
(2005)
Mutat Res
, vol.570
, pp. 205-214
-
-
Malfatti, M.A.1
Wu, R.W.2
Felton, J.S.3
-
12
-
-
77957237159
-
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
-
Malhotra D, Portales-Casamar E, Singh A, et al. Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res 2010;38:5718-34.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 5718-5734
-
-
Malhotra, D.1
Portales-Casamar, E.2
Singh, A.3
-
13
-
-
81155126130
-
Novel insights into the regulation of antioxidant-response-element mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2
-
Jyrkkanen HK, Kuosmanen S, Heinanieni M, Laitinen H, Kansanen E, Mella-aho E, Leinonen H, Yla-Herttuala S, Levonen AL. Novel insights into the regulation of antioxidant-response-element mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2. Biochem J 2011;440:167-74.
-
(2011)
Biochem J
, vol.440
, pp. 167-174
-
-
Jyrkkanen, H.K.1
Kuosmanen, S.2
Heinanieni, M.3
Laitinen, H.4
Kansanen, E.5
Mella-aho, E.6
Leinonen, H.7
Yla-Herttuala, S.8
Levonen, A.L.9
-
14
-
-
0035940984
-
Functional characterization of transcription regulators that interact with the electrophile response element
-
Zhu M, Fahl WE. Functional characterization of transcription regulators that interact with the electrophile response element. Biochem Biophys Res Commun 2001;289:212-9.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 212-219
-
-
Zhu, M.1
Fahl, W.E.2
-
15
-
-
78751703950
-
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
-
Taguchi K, Motohashi H, Yamamoto M. Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution. Genes Cells 2011;16:123-40.
-
(2011)
Genes Cells
, vol.16
, pp. 123-140
-
-
Taguchi, K.1
Motohashi, H.2
Yamamoto, M.3
-
16
-
-
0035836698
-
An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen
-
Chan K, Han XD, Kan YW. An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen. Proc Natl Acad Sci USA 2001;98:4611-6.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4611-4616
-
-
Chan, K.1
Han, X.D.2
Kan, Y.W.3
-
17
-
-
49149126354
-
Disruption of Nrf2 enhances inflammatory responses induced by low-dose diesel exhaust particles in mice
-
Li YJ, Takizawa H, Azuma A, Kohyama T, Yamauchi Y, Takahashi S, Yamamoto M, Kawada T, Kudoh S, Sugawara I. Disruption of Nrf2 enhances inflammatory responses induced by low-dose diesel exhaust particles in mice. Clin Immunol 2008;128:366-73.
-
(2008)
Clin Immunol
, vol.128
, pp. 366-373
-
-
Li, Y.J.1
Takizawa, H.2
Azuma, A.3
Kohyama, T.4
Yamauchi, Y.5
Takahashi, S.6
Yamamoto, M.7
Kawada, T.8
Kudoh, S.9
Sugawara, I.10
-
18
-
-
33846264538
-
Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis
-
Khort TO, Huang MT, Kwon KH, Chan JY, Reddy BS, Kong AN. Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis. Cancer Res 2006;66:11580-4.
-
(2006)
Cancer Res
, vol.66
, pp. 11580-11584
-
-
Khort, T.O.1
Huang, M.T.2
Kwon, K.H.3
Chan, J.Y.4
Reddy, B.S.5
Kong, A.N.6
-
19
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
-
Ramos-Gomez M, Kwak K, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci USA 2001;98:3410-5.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
Talalay, P.6
Kensler, T.W.7
-
20
-
-
75349110758
-
Sulforaphane protects against cisplatin-induced nephrotoxicity
-
Guerrero-Beltran CE, Calderon-Oliver M, Tapia E, Medina-Campos ON, Sanchez-Gonzalez DJ, Martinez-Martinez CM, Ortiz-Vega KM, Franco M, Pedraza-Chaverri J. Sulforaphane protects against cisplatin-induced nephrotoxicity. Toxicol Lett 2010;192:278-85.
-
(2010)
Toxicol Lett
, vol.192
, pp. 278-285
-
-
Guerrero-Beltran, C.E.1
Calderon-Oliver, M.2
Tapia, E.3
Medina-Campos, O.N.4
Sanchez-Gonzalez, D.J.5
Martinez-Martinez, C.M.6
Ortiz-Vega, K.M.7
Franco, M.8
Pedraza-Chaverri, J.9
-
21
-
-
34347392512
-
Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury
-
Marzec JM, Christie JD, Reddy SP, et al. Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury. FASEB J 2007;21:2237-46.
-
(2007)
FASEB J
, vol.21
, pp. 2237-2246
-
-
Marzec, J.M.1
Christie, J.D.2
Reddy, S.P.3
-
22
-
-
77956252901
-
The NRF2 gene variant, -653G/A, is associated with nephritis in childhood-onset systemic lupus erythematosus
-
Cordova EJ, Velazquez-Cruz R, Centeno F, Baca V, Orozco L. The NRF2 gene variant, -653G/A, is associated with nephritis in childhood-onset systemic lupus erythematosus. Lupus 2010;19:1237-42.
-
(2010)
Lupus
, vol.19
, pp. 1237-1242
-
-
Cordova, E.J.1
Velazquez-Cruz, R.2
Centeno, F.3
Baca, V.4
Orozco, L.5
-
23
-
-
77249083614
-
Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract
-
Von Otter M, Landgren S, Nilsson S, et al. Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract. Mech Ageing Dev 2010;131:105-10.
-
(2010)
Mech Ageing Dev
, vol.131
, pp. 105-110
-
-
Von Otter, M.1
Landgren, S.2
Nilsson, S.3
-
24
-
-
77951176535
-
Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease
-
Von Otter M, Landgren S, Nilsson S, et al. Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease. BMC Med Genet 2010;2:11-36.
-
(2010)
BMC Med Genet
, vol.2
, pp. 11-36
-
-
Von Otter, M.1
Landgren, S.2
Nilsson, S.3
-
25
-
-
24344479164
-
Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes
-
Katsuoka F, Motohashi H, Ishii T, Aburatani H, Engel JD, Yamamoto M. Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes. Mol Cell Biol 2005;25:8044-51.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8044-8051
-
-
Katsuoka, F.1
Motohashi, H.2
Ishii, T.3
Aburatani, H.4
Engel, J.D.5
Yamamoto, M.6
-
26
-
-
0032527757
-
Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice
-
Shavit JA, Motohashi H, Onodera K, Akasaka J, Yamamoto M, Engel JD. Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice. Genes Dev 1998;12:2164-74.
-
(1998)
Genes Dev
, vol.12
, pp. 2164-2174
-
-
Shavit, J.A.1
Motohashi, H.2
Onodera, K.3
Akasaka, J.4
Yamamoto, M.5
Engel, J.D.6
-
27
-
-
2342511435
-
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway
-
Motohashi H, Katsuoka F, Engel JD, Yamamoto M. Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway. Proc Natl Acad Sci USA 2004;101:6379-84.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6379-6384
-
-
Motohashi, H.1
Katsuoka, F.2
Engel, J.D.3
Yamamoto, M.4
-
28
-
-
77955081986
-
Differential contributions of rare and common, coding and noncoding Ret mutations to multifactorial Hirschsprung disease liability
-
Emison ES, Garcia-Barcelo M, Grice EA, et al. Differential contributions of rare and common, coding and noncoding Ret mutations to multifactorial Hirschsprung disease liability. Am J Hum Genet 2010;87:60-74.
-
(2010)
Am J Hum Genet
, vol.87
, pp. 60-74
-
-
Emison, E.S.1
Garcia-Barcelo, M.2
Grice, E.A.3
-
29
-
-
13444270902
-
The MAPPER database: a multi-genome catalog of putative transcription factor binding sites
-
Marinescu VD, Kohane IS, Riva A. The MAPPER database: a multi-genome catalog of putative transcription factor binding sites. Nucleic Acids Res 2005;33:D91-7.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Marinescu, V.D.1
Kohane, I.S.2
Riva, A.3
-
30
-
-
77957821749
-
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer
-
Wang X, Chorley BN, Pittman GS, Kleeberger SR, Brothers J 2nd, Liu G, Spira A, Bell DA. Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. PLoS One 2010;5:e11934.
-
(2010)
PLoS One
, vol.5
-
-
Wang, X.1
Chorley, B.N.2
Pittman, G.S.3
Kleeberger, S.R.4
Brothers II, J.5
Liu, G.6
Spira, A.7
Bell, D.A.8
-
31
-
-
0033597860
-
Characterization of the murine mafF gene
-
Onodera K, Shavit JA, Motohashi H, Katsuoka F, Akasaka JE, Engel JD, Yamamoto M. Characterization of the murine mafF gene. J Biol Chem 1999;274:21162-9.
-
(1999)
J Biol Chem
, vol.274
, pp. 21162-21169
-
-
Onodera, K.1
Shavit, J.A.2
Motohashi, H.3
Katsuoka, F.4
Akasaka, J.E.5
Engel, J.D.6
Yamamoto, M.7
-
32
-
-
0034653880
-
Perinatal synthetic lethality and hematopoietic defects in compound mafG:mafK mutant mice
-
Onodera K, Shavit JA, Motohashi H, Yamamoto M, Engel JD. Perinatal synthetic lethality and hematopoietic defects in compound mafG:mafK mutant mice. EMBO J 2000;19: 1335-45.
-
(2000)
EMBO J
, vol.19
, pp. 1335-1345
-
-
Onodera, K.1
Shavit, J.A.2
Motohashi, H.3
Yamamoto, M.4
Engel, J.D.5
-
33
-
-
84865747853
-
New associations of thegenetic polymorphisms in nicotinic receptor genes with the risk of lung cancer
-
Chikova A, Bernard HU, Shchepotin IB, Grando SA. New associations of thegenetic polymorphisms in nicotinic receptor genes with the risk of lung cancer. Life Sci 2012;91:1103-8.
-
(2012)
Life Sci
, vol.91
, pp. 1103-1108
-
-
Chikova, A.1
Bernard, H.U.2
Shchepotin, I.B.3
Grando, S.A.4
-
34
-
-
84856573895
-
The association between Toll-like receptor 2 single-nucleotide polymorphisms and hepatocellular carcinoma susceptibility
-
Junjie X, Songyao J, Minmin S, Yanyan S, Baiyong S, Xiaxing D, Jiabin J, Xi Z, Hao C. The association between Toll-like receptor 2 single-nucleotide polymorphisms and hepatocellular carcinoma susceptibility. BMC Cancer 2012;12:57.
-
(2012)
BMC Cancer
, vol.12
, pp. 57
-
-
Junjie, X.1
Songyao, J.2
Minmin, S.3
Yanyan, S.4
Baiyong, S.5
Xiaxing, D.6
Jiabin, J.7
Xi, Z.8
Hao, C.9
-
35
-
-
84874680750
-
A frequent PNPLA3 variant is a sex specific disease modifier in PSC patients with bile duct stenosis
-
Friedrich K, Rupp C, Hov JR, et al. A frequent PNPLA3 variant is a sex specific disease modifier in PSC patients with bile duct stenosis. PLoS One 2013;8:e58734.
-
(2013)
PLoS One
, vol.8
-
-
Friedrich, K.1
Rupp, C.2
Hov, J.R.3
-
36
-
-
0034595316
-
Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in Japanese men: the Suita Study
-
Higaki J, Baba S, Katsuy T, Sato N, Mannami T, Ogata J, Ogihara T. Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in Japanese men: the Suita Study. Circulation 2000;101:2060-5.
-
(2000)
Circulation
, vol.101
, pp. 2060-2065
-
-
Higaki, J.1
Baba, S.2
Katsuy, T.3
Sato, N.4
Mannami, T.5
Ogata, J.6
Ogihara, T.7
-
37
-
-
0345486977
-
Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study
-
O'Donnell CJ, Lindpaintner K, Larson MG, Rao VS, Ordovas JM, Schaefer Ej, Myers RH, Levy D. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study. Circulation 1998;97:1766-72.
-
(1998)
Circulation
, vol.97
, pp. 1766-1772
-
-
O'Donnell, C.J.1
Lindpaintner, K.2
Larson, M.G.3
Rao, V.S.4
Ordovas, J.M.5
Schaefer, E.6
Myers, R.H.7
Levy, D.8
-
38
-
-
0036428807
-
Angiotensin I-converting enzyme gene polymorphism in a Serbian population: a gender-specific association with hypertension
-
Stankovic A, Zivkovic M, Alavantic D. Angiotensin I-converting enzyme gene polymorphism in a Serbian population: a gender-specific association with hypertension. Scand J Clin Lab Invest 2002;62:469-75.
-
(2002)
Scand J Clin Lab Invest
, vol.62
, pp. 469-475
-
-
Stankovic, A.1
Zivkovic, M.2
Alavantic, D.3
-
39
-
-
56549099067
-
Sex-specific genetic architecture of human disease
-
Ober C, Loisel DA, Gilad Y. Sex-specific genetic architecture of human disease. Nat Rev Genet 2008;9:911-22.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 911-922
-
-
Ober, C.1
Loisel, D.A.2
Gilad, Y.3
-
40
-
-
84859496757
-
Genetic variants in antioxidant pathway: risk factors for hepatotoxicity in tuberculosis patients
-
Nanashima K, Mawatari T, Tahara N, et al. Genetic variants in antioxidant pathway: risk factors for hepatotoxicity in tuberculosis patients. Tuberculosis (Edinb) 2012;92:253-9.
-
(2012)
Tuberculosis (Edinb)
, vol.92
, pp. 253-259
-
-
Nanashima, K.1
Mawatari, T.2
Tahara, N.3
|