Suppression of tumorigenesis in mitochondrial NADP+-dependent isocitrate dehydrogenase knock-out mice

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1842, Issue 2, 2014, Pages 135-143

  Kim, Seontae ^a   Kim, Sung Youl ^a   Ku, Hyeong Jun ^a   Jeon, Yong Hyun ^b   Lee, Ho Won ^b   Lee, Jaetae ^b   Kwon, Taeg Kyu ^c   Park, Kwon Moo ^b   Park, Jeen Woo ^a  

^a Kyungpook National University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c Keimyung University   (South Korea)

Author keywords

Antioxidant enzyme; Host microenvironment; Knockout mice; Redox status; Tumorigenesis

Indexed keywords

CYCLIN D2; CYCLIN D3; CYCLIN DEPENDENT KINASE; ENOLASE; ENOLASE 1; FLAVOPROTEIN; GLUTATHIONE PEROXIDASE; HEXOKINASE 1; HEXOKINASE ISOENZYME; HYPOXIA INDUCIBLE FACTOR 1; ISOCITRATE DEHYDROGENASE 2; LACTATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PEROXIREDOXIN 3; PEROXIREDOXIN 5; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; PHOSPHOTRANSFERASE; PROTEIN P21; PYRUVATE DEHYDROGENASE; PYRUVATE KINASE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOREDOXIN REDUCTASE; TRIOSEPHOSPHATE ISOMERASE; TUMOR MARKER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOLUMINESCENCE; CANCER GROWTH; CANCER INHIBITION; CANCER SIZE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; IONIZING RADIATION; LIPID PEROXIDATION; MELANOMA; MELANOMA CELL; MITOCHONDRION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDOX STRESS; SKIN CARCINOGENESIS; SOUTHERN BLOTTING; TUMOR MICROENVIRONMENT;

ANTIOXIDANT ENZYME; HOST MICROENVIRONMENT; KNOCKOUT MICE; REDOX STATUS; TUMORIGENESIS;

ANIMALS; CARCINOGENESIS; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSE TRANSPORTER TYPE 1; HYDROGEN PEROXIDE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOBLOTTING; ISOCITRATE DEHYDROGENASE; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR BURDEN; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84890204814     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2013.11.008     Document Type: Article

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