Neutral biodegradable lipid-envelope-type nanoparticle using vitamin A-Scaffold for nuclear targeting of plasmid DNA

Biomaterials

Volumn 35, Issue 5, 2014, Pages 1755-1761

  Tanaka, Hiroki ^a   Akita, Hidetaka ^a   Ishiba, Ryohei ^a   Tange, Kota ^b   Arai, Masaya ^b   Kubo, Kazuhiro ^b   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NOF Corporation   (Japan)

Author keywords

DNA; Drug delivery; Liposome; Nanoparticle; Retinoid

Indexed keywords

DIFFUSION LIMITED; DISULFIDE BONDING; INTRACELLULAR IMAGING; LIPID NANOPARTICLES; NUCLEAR TRANSPORT; PLASMID DNA (PDNA); RETINOID; TERTIARY AMINE GROUPS;

BIOMOLECULES; CELLS; CYTOLOGY; DNA; DRUG DELIVERY; GENE EXPRESSION; GENE TRANSFER; LIPOSOMES; NANOPARTICLES;

SCAFFOLDS (BIOLOGY);

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; BIODEGRADABLE LIPID NANOPARTICLE; FLUORESCENT DYE; LIPID; NANOPARTICLE; PLASMID DNA; RETINOIC ACID; RETINOL; TERTIARY AMINE; UNCLASSIFIED DRUG;

ACTIVE TRANSPORT; ARTICLE; CELL MIGRATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CYTOPLASM; DISULFIDE BOND; ENDOCYTOSIS; ENDOSOME; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HYDROPHOBICITY; MOLECULAR IMAGING; NANOENCAPSULATION; PH; PRIORITY JOURNAL; TRANSGENE; TRANSMISSION ELECTRON MICROSCOPY;

DNA; DRUG DELIVERY; LIPOSOME; NANOPARTICLE; RETINOID;

BIOCOMPATIBLE MATERIALS; CELL COMPARTMENTATION; CELL LINE, TUMOR; CELL NUCLEUS; DNA; ENDOSOMES; FLUORESCENT DYES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPIDS; NANOPARTICLES; PLASMIDS; VITAMIN A;

EID: 84890169181     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.11.016     Document Type: Article

References (23)

1. Felgner P.L., Gadek T.R., Holm M., Roman R., Chan H.W., Wenz M., et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci U S A 1987, 84:7413-7417.
2. Thomas M., Klibanov A.M. Non-viral gene therapy: polycation-mediated DNA delivery. Appl Microbiol Biotechnol 2003, 62:27-34.
3. Kichler A., Mason A.J., Bechinger B. Cationic amphipathic histidine-rich peptides for gene delivery. Biochim Biophys Acta 2006, 1758:301-307.
4. Srinivas R., Samanta S., Chaudhuri A. Cationic amphiphiles: promising carriers of genetic materials in gene therapy. Chem Soc Rev 2009, 38:3326-3338.
5. Wiethoff C.M., Smith J.G., Koe G.S., Middaugh C.R. The potential role of proteoglycans in cationic lipid-mediated gene delivery. Studies of the interaction of cationic lipid-DNA complexes with model glycosaminoglycans. JBiol Chem 2001, 276:32806-32813.
6. Masotti A., Mossa G., Cametti C., Ortaggi G., Bianco A., Grosso N.D., et al. Comparison of different commercially available cationic liposome-DNA lipoplexes: parameters influencing toxicity and transfection efficiency. Colloids Surf B Biointerfaces 2009, 68:136-144.
7. Hama S., Akita H., Ito R., Mizuguchi H., Hayakawa T., Harashima H. Quantitative comparison of intracellular trafficking and nuclear transcription between adenoviral and lipoplex systems. Mol Ther 2006, 13:786-794.
8. Hama S., Akita H., Iida S., Mizuguchi H., Harashima H. Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex. Nucleic Acids Res 2007, 35:1533-1543.
9. Feener E.P., Shen W.C., Ryser H.J. Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes. JBiol Chem 1990, 265:18780-18785.
10. Nishina K., Unno T., Uno Y., Kubodera T., Kanouchi T., Mizusawa H., et al. Efficient invivo delivery of siRNA to the liver by conjugation of alpha-tocopherol. Mol Ther 2008, 16:734-740.
11. Kuwahara H., Nishina K., Yoshida K., Nishina T., Yamamoto M., Saito Y., et al. Efficient invivo delivery of siRNA into brain capillary endothelial cells along with endogenous lipoprotein. Mol Ther 2011, 19:2213-2221.
12. Sato Y., Murase K., Kato J., Kobune M., Sato T., Kawano Y., et al. Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone. Nat Biotechnol 2008, 26:431-442.
13. Gaub M.P., Lutz Y., Ghyselinck N.B., Scheuer I., Pfister V., Chambon P., et al. Nuclear detection of cellular retinoic acid binding proteins I and II with new antibodies. JHistochem Cytochem 1998, 46:1103-1111.
14. Dong D., Ruuska S.E., Levinthal D.J., Noy N. Distinct roles for cellular retinoic acid-binding proteins I and II in regulating signaling by retinoic acid. JBiol Chem 1999, 274:23695-23698.
15. Budhu A.S., Noy N. Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest. Mol Cell Biol 2002, 22:2632-2641.
16. Majumdar A., Petrescu A.D., Xiong Y., Noy N. Nuclear translocation of cellular retinoic acid-binding protein II is regulated by retinoic acid-controlled SUMOylation. JBiol Chem 2011, 286:42749-42757.
17. Akita H., Ishiba R., Hatakeyama H., Tanaka H., Sato Y., Tange K., et al. Aneutral envelope-type nanoparticle containing pH-responsive and SS-cleavable lipid-like materials as a carrier for plasmid DNA. Adv Healthc Mater 2013, 2:1120-1125.
18. Jeffs L.B., Palmer L.R., Ambegia E.G., Giesbrecht C., Ewanick S., MacLachlan I. Ascalable, extrusion-free method for efficient liposomal encapsulation of plasmid DNA. Pharm Res 2005, 22:362-372.
19. Varkouhi A.K., Scholte M., Storm G., Haisma H.J. Endosomal escape pathways for delivery of biologicals. JControl Release Off J Control Release Soc 2011, 151:220-228.
20. Yoshimori T., Yamamoto A., Moriyama Y., Futai M., Tashiro Y. Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. JBiol Chem 1991, 266:17707-17712.
21. McGrane M.M. Vitamin A regulation of gene expression: molecular mechanism of a prototype gene. JNutr Biochem 2007, 18:497-508.
22. Ziouzenkova O., Plutzky J. Retinoid metabolism and nuclear receptor responses: new insights into coordinated regulation of the PPAR-RXR complex. FEBS Lett 2008, 582:32-38.
23. Bushue N., Wan Y.J. Retinoid pathway and cancer therapeutics. Adv Drug Deliv Rev 2010, 62:1285-1298.