Valproic acid for the treatment of hemorrhagic shock: A dose-optimization study

Journal of Surgical Research

Volumn 186, Issue 1, 2014, Pages 363-370

  Hwabejire, John O ^a   Lu, Jennifer ^a   Liu, Baoling ^a,b   Li, Yongqing ^a   Halaweish, Ihab ^b   Alam, Hasan B ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

Author keywords

Dose optimization; Hemorrhagic shock; Histone deacetylase inhibitors; Valproic acid

Indexed keywords

HISTONE H3; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DOSE ESCALATION; HEMORRHAGIC SHOCK; HISTONE ACETYLATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL; WESTERN BLOTTING;

DOSE OPTIMIZATION; HEMORRHAGIC SHOCK; HISTONE DEACETYLASE INHIBITORS; VALPROIC ACID;

ACETYLATION; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOGEN SYNTHASE KINASE 3; HISTONES; MALE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, HEMORRHAGIC; VALPROIC ACID;

EID: 84890129242     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.09.016     Document Type: Article

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