Pharmacologic modulation of cerebral metabolic derangement and excitotoxicity in a porcine model of traumatic brain injury and hemorrhagic shock

Surgery (United States)

Volumn 154, Issue 2, 2013, Pages 234-243

  Hwabejire, John O ^a   Jin, Guang ^a,b   Imam, Ayesha M ^a   Duggan, Michael ^a   Sillesen, Martin ^a   Deperalta, Danielle ^a   Jepsen, Cecilie H ^a   Lu, Jennifer ^a   Li, Yongqing ^a   Demoya, Marc A ^a   Alam, Hasan B ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; FRESH FROZEN PLASMA; GLUCOSE; GLUTAMIC ACID; GLYCEROL; LACTIC ACID; OXIDOREDUCTASE; PYRUVIC ACID; VALPROIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN DAMAGE; BRAIN METABOLISM; BRAIN PERFUSION; CONTROLLED STUDY; CYTOSOLIC FRACTION; EXCITOTOXICITY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE BRAIN LEVEL; GLUCOSE UTILIZATION; HEMODYNAMICS; HEMORRHAGIC SHOCK; INTRACRANIAL PRESSURE; MICRODIALYSIS; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; RESUSCITATION; SWINE; TRAUMATIC BRAIN INJURY;

ADENOSINE TRIPHOSPHATE; ANIMALS; BLOOD GLUCOSE; BRAIN; BRAIN INJURIES; CALCIUM; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; FEMALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICRODIALYSIS; NEUROPROTECTIVE AGENTS; PYRUVATE DEHYDROGENASE COMPLEX; SHOCK, HEMORRHAGIC; SWINE; VALPROIC ACID;

EID: 84880884866     PISSN: 00396060     EISSN: 15327361     Source Type: Journal    
DOI: 10.1016/j.surg.2013.04.008     Document Type: Article

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