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Whole body vibration exercise improves body balance and walking velocity in postmenopausal osteoporotic women treated with alendronate: Galileo and Alendronate Intervention Trail (GAIT)
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Iwamoto J, Sato Y, Takeda T, Matsumoto H. Whole body vibration exercise improves body balance and walking velocity in postmenopausal osteoporotic women treated with alendronate: Galileo and Alendronate Intervention Trail (GAIT). J Musculoskelet Neuronal Interact 2012; 12:136-143.
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84878119219
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Diagnosis and treatment of osteoporosis in older adults
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This article provides a thorough updated review focusing on the treatment of elderly subjects with osteoporosis
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Diab DL, Watts NB. Diagnosis and treatment of osteoporosis in older adults. Endocrinol Metab Clin North Am 2013; 42:305-317. This article provides a thorough updated review focusing on the treatment of elderly subjects with osteoporosis.
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Diab, D.L.1
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Screening for osteoporosis: U.S. Preventive services task force recommendation statement
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U.S. Preventive Services Task Force
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U.S. Preventive Services Task Force. Screening for osteoporosis: U.S. preventive services task force recommendation statement. Ann Intern Med 2011; 154:356-364.
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Secondary osteoporosis: Differential diagnosis and workup
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Diab DL, Watts NB. Secondary osteoporosis: differential diagnosis and workup. Clin Obstet Gynecol 2013. [Epub ahead of print]
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Clin. Obstet. Gynecol.
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Diab, D.L.1
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American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of postmenopausal osteoporosis
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Watts NB, Bilezikian JP, Camacho PM, et al. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of postmenopausal osteoporosis. Endocr Pract 2010; 16 (Suppl 3):1-37.
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Endocr. Pract.
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Watts, N.B.1
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Search for hidden secondary causes in postmenopausal women with osteoporosis
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Cerda Gabaroi D, Peris P, Monegal A, et al. Search for hidden secondary causes in postmenopausal women with osteoporosis. Menopause 2010; 17:135-139.
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Cerda Gabaroi, D.1
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8
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Secondary causes of osteoporosis
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This article provides an updated review of several causes of secondary osteoporosis as well as screening recommendations for these disorders
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Hudec SM, Camacho PM. Secondary causes of osteoporosis. Endocr Pract 2013; 19:120-128. This article provides an updated review of several causes of secondary osteoporosis as well as screening recommendations for these disorders.
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Hudec, S.M.1
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9
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Search for secondary osteoporosis: Are Z scores useful predictors?
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Swaminathan K, Flynn R, Garton M, et al. Search for secondary osteoporosis: are Z scores useful predictors?. Postgrad Med J 2009; 85:38-39.
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Swaminathan, K.1
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The utility of BMD Z-score diagnostic thresholds for secondary causes of osteoporosis
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McKiernan FE, Berg RL, Linneman JG. The utility of BMD Z-score diagnostic thresholds for secondary causes of osteoporosis. Osteoporos Int 2011; 22:1069-1077.
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11
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84876285549
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The prevalence of recognized contributors to secondary osteoporosis in South East Asian men and postmenopausal women. Are Z score diagnostic thresholds useful predictors of their presence?
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This manuscript emphasizes the importance of not solely relying on z score diagnostic thresholds to discriminate between primary and secondary osteoporosis
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Yung CK, Fook-Chong S, Chandran M. The prevalence of recognized contributors to secondary osteoporosis in South East Asian men and postmenopausal women. Are Z score diagnostic thresholds useful predictors of their presence? Arch Osteoporos 2012; 7:49-56. This manuscript emphasizes the importance of not solely relying on z score diagnostic thresholds to discriminate between primary and secondary osteoporosis.
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Arch. Osteoporos.
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Yung, C.K.1
Fook-Chong, S.2
Chandran, M.3
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12
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84873736574
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Health risks and benefits from calcium and vitamin D supplementation: Women's Health Initiative clinical trial and cohort study
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This study examines the health benefits and risks of calcium and vitamin D supplementation using WHI data, with emphasis on fractures, cardiovascular disease, cancer, and total mortality
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Prentice RL, Pettinger MB, Jackson RD, et al. Health risks and benefits from calcium and vitamin D supplementation: Women's Health Initiative clinical trial and cohort study. Osteoporos Int 2013; 24:567-580. This study examines the health benefits and risks of calcium and vitamin D supplementation using WHI data, with emphasis on fractures, cardiovascular disease, cancer, and total mortality.
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Osteoporos. Int.
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Prentice, R.L.1
Pettinger, M.B.2
Jackson, R.D.3
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13
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Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: A meta-analysis
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Tang BM, Eslick GD, Nowson C, et al. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis. Lancet 2007; 370: 657-666.
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Lancet
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Tang, B.M.1
Eslick, G.D.2
Nowson, C.3
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15
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84863526518
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A pooled analysis of vitamin D dose requirements for fracture prevention
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This is a large analysis of 11 double-blind, randomized, controlled trials of oral vitamin D looking at the effect of vitamin D supplementation on fracture risk reduction
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Bischoff-Ferrari HA, Willett WC, Orav EJ, et al. A pooled analysis of vitamin D dose requirements for fracture prevention. N Engl J Med 2012; 367:40-49. This is a large analysis of 11 double-blind, randomized, controlled trials of oral vitamin D looking at the effect of vitamin D supplementation on fracture risk reduction.
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N. Engl. J. Med.
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Bischoff-Ferrari, H.A.1
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Orav, E.J.3
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16
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84866146531
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The nonskeletal effects of vitamin D: An Endocrine Society scientific statement
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This article reviews both the basic and clinical aspects of vitamin D in relation to nonskeletal organ systems
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Rosen CJ, Adams JS, Bikle DD, et al. The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. Endocr Rev 2012; 33:456-492. This article reviews both the basic and clinical aspects of vitamin D in relation to nonskeletal organ systems.
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Endocr. Rev.
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Rosen, C.J.1
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Evaluation, treatment, and prevention of vitamin D deficiency: An Endocrine Society clinical practice guideline
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Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011; 96:1911-1930.
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Holick, M.F.1
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Bischoff-Ferrari, H.A.3
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18
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84859554832
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Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited
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This manuscript summarizes the current evidence and guidelines for preventing and treating vitamin D deficiency
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Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited. J Clin Endocrinol Metab 2012; 97:1153-1158. This manuscript summarizes the current evidence and guidelines for preventing and treating vitamin D deficiency.
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Holick, M.F.1
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19
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40849085157
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Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D
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Holick MF, Biancuzzo RM, Chen TC, et al. Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D. J Clin Endocrinol Metab 2008; 93:677-681.
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Holick, M.F.1
Biancuzzo, R.M.2
Chen, T.C.3
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20
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84861551708
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Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: A systematic review and meta-analysis
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This is a large review and meta-analysis comparing vitamin D2 and D3 effectiveness in adults
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Tripkovic L, Lambert H, Hart K, et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. Am J Clin Nutr 2012; 95:1357-1364. This is a large review and meta-analysis comparing vitamin D2 and D3 effectiveness in adults.
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Am. J. Clin. Nutr.
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Tripkovic, L.1
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Risk factors for falls and fall-related injuries in adults 85 years of age and older
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Grundstrom AC, Guse CE, Layde PM. Risk factors for falls and fall-related injuries in adults 85 years of age and older. Arch Gerontol Geriatr 2012; 54:421-428.
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Grundstrom, A.C.1
Guse, C.E.2
Layde, P.M.3
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22
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84871177309
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Interventions for preventing falls in older people living in the community
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This is an update of a Cochrane review first published in 2009, which assesses the effects of interventions designed to reduce the incidence of falls in older people living in the community
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Gillespie LD, Robertson MC, Gillespie WJ, et al. Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev 2012; 9:CD007146. This is an update of a Cochrane review first published in 2009, which assesses the effects of interventions designed to reduce the incidence of falls in older people living in the community.
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Cochrane Database Syst. Rev.
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Gillespie, L.D.1
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Falls prevention in older adults-assessment and management
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Waldron N, Hill AM, Barker A. Falls prevention in older adults - assessment and management. Aust Fam Physician 2012; 41:930-935.
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Aust. Fam. Physician
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Waldron, N.1
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Management of osteoporosis among the elderly with other chronic medical conditions
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Curtis JR, Safford MM. Management of osteoporosis among the elderly with other chronic medical conditions. Drugs Aging 2012; 29:549-564.
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Drugs Aging
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Curtis, J.R.1
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25
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A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: The prevent recurrence of osteoporotic fractures study
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Chesnut CH 3rd, Silverman S, Andriano K, et al., PROOF Study Group. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. Am J Med 2000; 109:267-276.
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Chesnut III, C.H.1
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Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: Results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators
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Ettinger B, Black DM, Mitlak BH, et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. Jama 1999; 282:637-645.
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Ettinger, B.1
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27
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84875147170
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Fractures in women treated with raloxifene or alendronate: A retrospective database analysis
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This is the first retrospective cohort study evaluating fracture and breast cancer rates among patients treated with raloxifene or alendronate
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Foster SA, Shi N, Curkendall S, et al. Fractures in women treated with raloxifene or alendronate: a retrospective database analysis. BMC Womens Health 2013; 13:15. This is the first retrospective cohort study evaluating fracture and breast cancer rates among patients treated with raloxifene or alendronate.
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BMC Womens Health
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Foster, S.A.1
Shi, N.2
Curkendall, S.3
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28
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84861723097
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Long-term treatment with raloxifene, but not bisphosphonates, reduces circulating sclerostin levels in postmenopausal women
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This study provides insight into the mechanism of action of estrogen on bone metabolism
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Chung YE, Lee SH, Lee SY, et al. Long-term treatment with raloxifene, but not bisphosphonates, reduces circulating sclerostin levels in postmenopausal women. Osteoporos Int 2012; 23:1235-1243. This study provides insight into the mechanism of action of estrogen on bone metabolism.
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Osteoporos Int.
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Chung, Y.E.1
Lee, S.H.2
Lee, S.Y.3
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29
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Bisphosphonates in the treatment of osteoporosis
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This article provides a thorough updated review of the use of bisphosphonates in the treatment of osteoporosis
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Diab DL, Watts NB. Bisphosphonates in the treatment of osteoporosis. Endocrinol Metab Clin North Am 2012; 41:487-506. This article provides a thorough updated review of the use of bisphosphonates in the treatment of osteoporosis.
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Endocrinol. Metab. Clin. North. Am.
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Diab, D.L.1
Watts, N.B.2
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30
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84856184102
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The effect of 3 versus 6 years of zoledronic acid treatment of osteoporosis: A randomized extension to the HORIZONPivotal Fracture Trial (PFT)
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This is a landmark international, multicenter, double-blind, placebo-controlled extension trial assessing the risks and benefits of stopping zoledronic acid therapy at 3 years versus continuing treatment up to 6 years
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Black DM, Reid IR, Boonen S, et al. The effect of 3 versus 6 years of zoledronic acid treatment of osteoporosis: a randomized extension to the HORIZONPivotal Fracture Trial (PFT). J Bone Miner Res 2012; 27:243-254. This is a landmark international, multicenter, double-blind, placebo-controlled extension trial assessing the risks and benefits of stopping zoledronic acid therapy at 3 years versus continuing treatment up to 6 years.
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J. Bone. Miner. Res.
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Black, D.M.1
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Seven years of treatment with risedronate in women with postmenopausal osteoporosis
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Mellstrom DD, Sorensen OH, Goemaere S, et al. Seven years of treatment with risedronate in women with postmenopausal osteoporosis. Calcif Tissue Int 2004; 75:462-468.
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Calcif. Tissue. Int.
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Mellstrom, D.D.1
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Goemaere, S.3
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Effects of continuing or stopping alendronate after 5 years of treatment: The Fracture Intervention Trial Longterm Extension (FLEX): A randomized trial
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Black DM, Schwartz AV, Ensrud KE, et al. Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Longterm Extension (FLEX): a randomized trial. Jama 2006; 296:2927-2938.
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Black, D.M.1
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Ensrud, K.E.3
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Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: The FLEX trial
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Schwartz AV, Bauer DC, Cummings SR, et al. Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: the FLEX trial. J Bone Miner Res 2010; 25:976-982.
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Schwartz, A.V.1
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Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research
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Khosla S, Burr D, Cauley J, et al. Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 2007; 22:1479-1491.
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J. Bone. Miner. Res.
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Khosla, S.1
Burr, D.2
Cauley, J.3
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35
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Incidence of atypical nontraumatic diaphyseal fractures of the femur
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This study provides new information on the risk of AFFs with long-term bisphosphonate use
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Dell RM, Adams AL, Greene DF, et al. Incidence of atypical nontraumatic diaphyseal fractures of the femur. J Bone Miner Res 2012; 27:2544-2550. This study provides new information on the risk of AFFs with long-term bisphosphonate use.
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J. Bone. Miner. Res.
, vol.27
, pp. 2544-2550
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Dell, R.M.1
Adams, A.L.2
Greene, D.F.3
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36
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Atypical subtrochanteric and diaphyseal femoral fractures: Second report of a task force of the American society for bone and mineral research
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[Epub ahead of print]. doi: 10.1002/jbmr.1998. This updated report summarizes the data currently available on AFFs and reviews studies on the epidemiology, pathogenesis, and medical management of AFFs published since 2010
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Shane E, Ebeling PR, Abrahamsen B, et al. Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American society for bone and mineral research. J Bone Miner Res 2013. [Epub ahead of print]. doi: 10.1002/jbmr.1998. This updated report summarizes the data currently available on AFFs and reviews studies on the epidemiology, pathogenesis, and medical management of AFFs published since 2010.
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J. Bone. Miner. Res.
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Shane, E.1
Ebeling, P.R.2
Abrahamsen, B.3
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37
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Increasing occurrence of atypical femoral fractures associated with bisphosphonate use
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This is another study providing new information on the risk of AFFs with long-term bisphosphonate use
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Meier RP, Perneger TV, Stern R, et al. Increasing occurrence of atypical femoral fractures associated with bisphosphonate use. Arch Intern Med 2012; 172:930-936. This is another study providing new information on the risk of AFFs with long-term bisphosphonate use.37
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Meier, R.P.1
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Stern, R.3
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38
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Bisphosphonates and risk of subtrochanteric, femoral shaft, and atypical femur fracture: A systematic review and meta-analysis
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This large meta-analysis also assesses the risk of AFFs with bisphosphonate use
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Gedmintas L, Solomon DH, Kim SC. Bisphosphonates and risk of subtrochanteric, femoral shaft, and atypical femur fracture: A systematic review and meta-analysis. J Bone Miner Res 2013; 28:1729-1737. This large meta-analysis also assesses the risk of AFFs with bisphosphonate use.
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J. Bone. Miner. Res.
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Gedmintas, L.1
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Kim, S.C.3
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Bisphosphonates for osteoporosis-where do we go from here?
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Whitaker M, Guo J, Kehoe T, Benson G. Bisphosphonates for osteoporosis-where do we go from here? N Engl J Med 2012; 366:2048-2051.
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Whitaker, M.1
Guo, J.2
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Benson, G.4
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40
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Use of drug holidays in women taking bisphosphonates
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[Epub ahead of print] This article summarizes our expert opinion regarding bisphosphonate drug holidays in postmenopausal women based on the current evidence
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Diab DL, Watts NB. Use of drug holidays in women taking bisphosphonates. Menopause 2013. [Epub ahead of print] This article summarizes our expert opinion regarding bisphosphonate drug holidays in postmenopausal women based on the current evidence.
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Diab, D.L.1
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41
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Bisphosphonate therapy for osteoporosis: The long and short of it
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Compston JE, Bilezikian JP. Bisphosphonate therapy for osteoporosis: the long and short of it. J Bone Miner Res 2012; 27:240-242.
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J. Bone. Miner. Res.
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Compston, J.E.1
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Bisphosphonate therapy for osteoporosis: Benefits, risks, and drug holiday
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McClung M, Harris ST, Miller PD, et al. Bisphosphonate therapy for osteoporosis: benefits, risks, and drug holiday. Am J Med 2013; 126:13-20.
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Am. J. Med.
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McClung, M.1
Harris, S.T.2
Miller, P.D.3
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44
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A new pharmacotherapy option for postmenopausal osteoporosis
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This is a recent thorough review of the use of denosumb in osteoporosis
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Josse R, Khan A, Ngui D, et al. a new pharmacotherapy option for postmenopausal osteoporosis. Curr Med Res Opin 2013; 29:205-216. This is a recent thorough review of the use of denosumb in osteoporosis.
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Curr. Med. Res. Opin.
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Josse, R.1
Khan, A.2
Ngui, D.3
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45
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84863116813
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Five years of denosumab exposure in women with postmenopausal osteoporosis: Results from the first two years of the FREEDOM extension
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This is an important study reporting the extension results of the FREEDOM trial and assessing the risk/benefit profile of denosumab with continued therapy up to 5 years
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Papapoulos S, Chapurlat R, Libanati C, et al. Five years of denosumab exposure in women with postmenopausal osteoporosis: results from the first two years of the FREEDOM extension. J Bone Miner Res 2012; 27:694-701. This is an important study reporting the extension results of the FREEDOM trial and assessing the risk/benefit profile of denosumab with continued therapy up to 5 years.
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J. Bone. Miner. Res.
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Papapoulos, S.1
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Libanati, C.3
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Treatment with denosumab reduces the incidence of new vertebral and hip fractures in postmenopausal women at high risk
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Boonen S, Adachi JD, Man Z, et al. Treatment with denosumab reduces the incidence of new vertebral and hip fractures in postmenopausal women at high risk. J Clin Endocrinol Metab 2011; 96:1727-1736.
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J. Clin. Endocrinol. Metab.
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Boonen, S.1
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Watts NB, Roux C, Modlin JF, et al. Infections in postmenopausal women with osteoporosis treated with denosumab or placebo: coincidence or causal association? Osteoporos Int 2012; 23:327-337. This paper provides a thorough review of serious adverse events of infections that occurred in subjects receiving denosumab or placebo in the FREEDOM trial.
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Tsai JN, Uihlein AV, Lee H, et al. Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial. Lancet 2013; 382:50-56. This is the first randomized study comparing the effects of teriparatide and denosumab alone or combined in postmenopausal women with osteoporosis.
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Subbiah V, Madsen VS, Raymond AK, et al. Of mice and men: divergent risks of teriparatide-induced osteosarcoma. Osteoporos Int 2010; 21:1041-1045.
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54
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This article provides an updated review of the safety of osteoanabolic therapy
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Cipriani C, Irani D, Bilezikian JP. Safety of osteoanabolic therapy: a decade of experience. J Bone Miner Res 2012; 27:2419-2428. This article provides an updated review of the safety of osteoanabolic therapy.
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55
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The US postmarketing surveillance study of adult osteosarcoma and teriparatide: Study design and findings from the first 7 years
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Andrews EB, Gilsenan AW, Midkiff K, et al. The US postmarketing surveillance study of adult osteosarcoma and teriparatide: study design and findings from the first 7 years. J Bone Miner Res 2012; 27:2429-2437.
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56
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This report describes a potential off-label benefit (ONJ) for teriparatide use
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Yoshiga D, Yamashita Y, Nakamichi I, et al. Weekly teriparatide injections successfully treated advanced bisphosphonate-related osteonecrosis of the jaws. Osteoporos Int 2013; 24:2365-2369. This report describes a potential off-label benefit (ONJ) for teriparatide use.
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57
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This article describes another potential off-label benefit (AFF) for teriparatide use
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Chiang CY, Zebaze RM, Ghasem-Zadeh A, et al. Teriparatide improves bone quality and healing of atypical femoral fractures associated with bisphosphonate therapy. Bone 2013; 52:360-365. This article describes another potential off-label benefit (AFF) for teriparatide use.
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Chiang, C.Y.1
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58
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This review describes the potential usefulness of cathepsin K inhibitors in treating postmenopausal women with osteoporosis
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Boonen S, Rosenberg E, Claessens F, et al. Inhibition of cathepsin K for treatment of osteoporosis. Curr Osteoporos Rep 2012; 10:73-79. This review describes the potential usefulness of cathepsin K inhibitors in treating postmenopausal women with osteoporosis.
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Boonen, S.1
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59
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This study reports the results of 5 years of odanacatib therapy, an emerging therapeutic option in the treatment of postmenopausal osteoporosis
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Langdahl B, Binkley N, Bone H, et al. Odanacatib in the treatment of postmenopausal women with low bone mineral density: five years of continued therapy in a phase 2 study. J Bone Miner Res 2012; 27:2251-2258. This study reports the results of 5 years of odanacatib therapy, an emerging therapeutic option in the treatment of postmenopausal osteoporosis.
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J. Bone. Miner. Res.
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Langdahl, B.1
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60
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This is the first randomized trial examining the effect of odanacatib on the trabecular and cortical bone compartments and estimated strength at the hip and spine in postmenopausal women
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Brixen K, Chapurlat R, Cheung AM, et al. Bone density, turnover, and estimated strength in postmenopausal women treated with odanacatib: a randomized trial. J Clin Endocrinol Metab 2013; 98:571-580. This is the first randomized trial examining the effect of odanacatib on the trabecular and cortical bone compartments and estimated strength at the hip and spine in postmenopausal women.
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J. Clin. Endocrinol. Metab.
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This is a recent review of the use of odanacatib in postmenopausal women with osteoporosis
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Zerbini CA, McClung MR. Odanacatib in postmenopausal women with low bone mineral density: a review of current clinical evidence. Ther Adv Musculoskelet Dis 2013; 5:199-209. This is a recent review of the use of odanacatib in postmenopausal women with osteoporosis.
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62
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This article provides a thorough review of the effects of sclerostin and DKK-1 on bone, along with the therapeutic potential of using antibodies targeted at these compounds
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Ke HZ, Richards WG, Li X, Ominsky MS. Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases. Endocr Rev 2012; 33:747-783. This article provides a thorough review of the effects of sclerostin and DKK-1 on bone, along with the therapeutic potential of using antibodies targeted at these compounds.
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Ke, H.Z.1
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This manuscript reviews the use of monoclonal antibodies in the treatment of osteoporosis
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Lewiecki EM. Monoclonal antibodies for the treatment of osteoporosis. Expert Opin Biol Ther 2013; 13:183-196. This manuscript reviews the use of monoclonal antibodies in the treatment of osteoporosis.
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Lewiecki, E.M.1
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Cosman F, Lane NE, Bolognese MA, et al. Effect of transdermal teriparatide administration on bone mineral density in postmenopausal women. J Clin Endocrinol Metab 2010; 95:151-158.
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65
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This is a thorough review of the use of osteoanabolic therapies for treating Osteoporosis
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Uihlein AV, Leder BZ. Anabolic therapies for osteoporosis. Endocrinol Metab Clin North Am 2012; 41:507-525. This is a thorough review of the use of osteoanabolic therapies for treating Osteoporosis
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Uihlein, A.V.1
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66
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This article evaluates a novel way of administering recombinant parathyroid hormone in treating postmenopausal osteoporosis
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Henriksen K, Andersen JR, Riis BJ, et al. Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH(1-31)NH(2)] in postmenopausal women with osteoporosis. Bone 2013; 53:160-166. This article evaluates a novel way of administering recombinant parathyroid hormone in treating postmenopausal osteoporosis.
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Bone
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67
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A comparison of parathyroid hormone-related protein (1-36) and parathyroid hormone (1-34) on markers of bone turnover and bone density in postmenopausal women: The PrOP study
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[Epub ahead of print]. doi: 10.1002/jbmr. 1978. This study reports encouraging results with the use of PTHrP (as compared to PTH) in treating postmenopausal women with low bone density or osteoporosis
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Horwitz MJ, Augustine M, Kahn L, et al. A comparison of parathyroid hormone-related protein (1-36) and parathyroid hormone (1-34) on markers of bone turnover and bone density in postmenopausal women: The PrOP study. J Bone Miner Res 2013. [Epub ahead of print]. doi: 10.1002/jbmr. 1978. This study reports encouraging results with the use of PTHrP (as compared to PTH) in treating postmenopausal women with low bone density or osteoporosis.
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J. Bone. Miner. Res.
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Esbrit P, Alcaraz MJ. Current perspectives on parathyroid hormone (PTH) and PTH-related protein (PTHrP) as bone anabolic therapies. Biochem Pharmacol 2013; 85:1417-1423.
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69
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This article highlights the fact that the prevalence of long-term bisphosphonate use may be low because of low refill compliance and gaps in treatment
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Abrahamsen B. Are long-term bisphosphonate users a reality? Dose years for current bisphosphonate users assessed using the danish national prescription database. Osteoporos Int 2013; 24:369-372. This article highlights the fact that the prevalence of long-term bisphosphonate use may be low because of low refill compliance and gaps in treatment.
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70
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Ziller V, Kostev K, Kyvernitakis I, et al. Persistence and compliance of medications used in the treatment of osteoporosis-analysis using a large scale, representative, longitudinal German database. Int J Clin Pharmacol Ther 2012; 50:315-322.
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71
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This retrospective cohort study emphasizes that better adherence with bisphosphonates appears to confer tangible benefits in terms of increases in BMD
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Weycker D, Lamerato L, Schooley S, et al. Adherence with bisphosphonate therapy and change in bone mineral density among women with osteoporosis or osteopenia in clinical practice. Osteoporos Int 2013; 24:1483-1489. This retrospective cohort study emphasizes that better adherence with bisphosphonates appears to confer tangible benefits in terms of increases in BMD.
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Osteoporos. Int.
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Gold DT, Silverman S. Review of adherence to medications for the treatment of osteoporosis. Curr Osteoporos Rep 2006; 4:21-27.
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This article describes the association between treatment satisfaction and the risk of discontinuation/switching postmenopausal osteoporosis medications using patient-reported data from a large, longitudinal cohort study and emphasizes the importance of treatment satisfaction for persistence with therapy
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Barrett-Connor E, Wade SW, Do TP, et al. Treatment satisfaction and persistence among postmenopausal women on osteoporosis medications: 12-month results from POSSIBLE US. Osteoporos Int 2012; 23:733-741. This article describes the association between treatment satisfaction and the risk of discontinuation/switching postmenopausal osteoporosis medications using patient-reported data from a large, longitudinal cohort study and emphasizes the importance of treatment satisfaction for persistence with therapy.
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Osteoporos. Int.
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Crandall, C.J.1
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79
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A randomized trial comparing monthly ibandronate and weekly alendronate for osteoporosis in patients with primary biliary cirrhosis
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[Epub ahead of print]. doi: 10.1002/hep.26466. This study suggests that adherence is higher with the less frequent dosing regimen of bisphosphonates
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Guanabens N, Monegal A, Cerda D, et al. A randomized trial comparing monthly ibandronate and weekly alendronate for osteoporosis in patients with primary biliary cirrhosis. Hepatology 2013. [Epub ahead of print]. doi: 10.1002/hep.26466. This study suggests that adherence is higher with the less frequent dosing regimen of bisphosphonates.
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Hepatology
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Guanabens, N.1
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80
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This article assesses different interventions aimed at increasing compliance with alendronate therapy
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Sewerynek E, Horst-Sikorska H, Stepien-Klos W, et al. The role of counselling and other factors in compliance of postmenopausal osteoporotic patients to alendronate 70 therapy. Arch Med Sci 2013; 9:288-296. This article assesses different interventions aimed at increasing compliance with alendronate therapy.
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Arch. Med. Sci.
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Sewerynek, E.1
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