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Volumn 41, Issue 3, 2012, Pages 507-525

Anabolic Therapies for Osteoporosis

Author keywords

Anabolic therapy; Bone mineral density; Osteoporosis; Parathyroid hormone; Teriparatide

Indexed keywords

ALENDRONIC ACID; ANABOLIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; CORTICOSTEROID; DICKKOPF 1 PROTEIN; GLUCOCORTICOID; PARATHYROID GLAND HORMONE; PARATHYROID HORMONE; PARATHYROID HORMONE RELATED PROTEIN [1-36]; PARATHYROID HORMONE[1-34]; PLACEBO; RALOXIFENE; SCLEROSTIN; UNCLASSIFIED DRUG; ZOLEDRONIC ACID;

EID: 84864825624     PISSN: 08898529     EISSN: 15584410     Source Type: Journal    
DOI: 10.1016/j.ecl.2012.05.002     Document Type: Review
Times cited : (27)

References (81)
  • 1
    • 0025374223 scopus 로고
    • Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis
    • Riggs B.L., Hodgson S.F., O'Fallon W.M., et al. Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis. N Engl J Med 1990, 322:802-809.
    • (1990) N Engl J Med , vol.322 , pp. 802-809
    • Riggs, B.L.1    Hodgson, S.F.2    O'Fallon, W.M.3
  • 2
    • 0000683821 scopus 로고
    • Studies of calcium and phosphorus metabolism: V. A study of the bone trabeculae as a readily available reserve supply of calcium
    • Bauer W., Aub J.C., Albright F. Studies of calcium and phosphorus metabolism: V. A study of the bone trabeculae as a readily available reserve supply of calcium. J Exp Med 1929, 49:145-162.
    • (1929) J Exp Med , vol.49 , pp. 145-162
    • Bauer, W.1    Aub, J.C.2    Albright, F.3
  • 3
    • 84919594266 scopus 로고
    • Anabolic effect of low doses of a fragment of human parathyroid hormone on the skeleton in postmenopausal osteoporosis
    • Reeve J., Hesp R., Williams D., et al. Anabolic effect of low doses of a fragment of human parathyroid hormone on the skeleton in postmenopausal osteoporosis. Lancet 1976, 1:1035-1038.
    • (1976) Lancet , vol.1 , pp. 1035-1038
    • Reeve, J.1    Hesp, R.2    Williams, D.3
  • 4
    • 0018839378 scopus 로고
    • Anabolic effect of human parathyroid hormone fragment on trabecular bone in involutional osteoporosis: a multicentre trial
    • Reeve J., Meunier P.J., Parsons J.A., et al. Anabolic effect of human parathyroid hormone fragment on trabecular bone in involutional osteoporosis: a multicentre trial. Br Med J 1980, 280:1340-1344.
    • (1980) Br Med J , vol.280 , pp. 1340-1344
    • Reeve, J.1    Meunier, P.J.2    Parsons, J.A.3
  • 5
    • 0022758151 scopus 로고
    • Restoration of spinal bone in osteoporotic men by treatment with human parathyroid hormone (1-34) and 1,25-dihydroxyvitamin D
    • Slovik D.M., Rosenthal D.I., Doppelt S.H., et al. Restoration of spinal bone in osteoporotic men by treatment with human parathyroid hormone (1-34) and 1,25-dihydroxyvitamin D. J Bone Miner Res 1986, 1:377-381.
    • (1986) J Bone Miner Res , vol.1 , pp. 377-381
    • Slovik, D.M.1    Rosenthal, D.I.2    Doppelt, S.H.3
  • 6
    • 0025324285 scopus 로고
    • Treatment of osteoporosis with human parathyroid peptide and observations on effect of sodium fluoride
    • Reeve J., Davies U.M., Hesp R., et al. Treatment of osteoporosis with human parathyroid peptide and observations on effect of sodium fluoride. BMJ 1990, 301:314-318.
    • (1990) BMJ , vol.301 , pp. 314-318
    • Reeve, J.1    Davies, U.M.2    Hesp, R.3
  • 7
    • 0024549034 scopus 로고
    • Increase of vertebral density by combination therapy with pulsatile 1-38hPTH and sequential addition of calcitonin nasal spray in osteoporotic patients
    • Hesch R.D., Busch U., Prokop M., et al. Increase of vertebral density by combination therapy with pulsatile 1-38hPTH and sequential addition of calcitonin nasal spray in osteoporotic patients. Calcif Tissue Int 1989, 44:176-180.
    • (1989) Calcif Tissue Int , vol.44 , pp. 176-180
    • Hesch, R.D.1    Busch, U.2    Prokop, M.3
  • 8
    • 0027985064 scopus 로고
    • Parathyroid hormone for the prevention of bone loss induced by estrogen deficiency
    • Finkelstein J.S., Klibanski A., Schaefer E.H., et al. Parathyroid hormone for the prevention of bone loss induced by estrogen deficiency. N Engl J Med 1994, 331:1618-1623.
    • (1994) N Engl J Med , vol.331 , pp. 1618-1623
    • Finkelstein, J.S.1    Klibanski, A.2    Schaefer, E.H.3
  • 9
    • 0027404941 scopus 로고
    • An evaluation of several biochemical markers for bone formation and resorption in a protocol utilizing cyclical parathyroid hormone and calcitonin therapy for osteoporosis
    • Hodsman A.B., Fraher L.J., Ostbye T., et al. An evaluation of several biochemical markers for bone formation and resorption in a protocol utilizing cyclical parathyroid hormone and calcitonin therapy for osteoporosis. J Clin Invest 1993, 91:1138-1148.
    • (1993) J Clin Invest , vol.91 , pp. 1138-1148
    • Hodsman, A.B.1    Fraher, L.J.2    Ostbye, T.3
  • 10
    • 0020064261 scopus 로고
    • Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: differential effects of intermittent and continuous administration
    • Tam C.S., Heersche J.N., Murray T.M., et al. Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: differential effects of intermittent and continuous administration. Endocrinology 1982, 110:506-512.
    • (1982) Endocrinology , vol.110 , pp. 506-512
    • Tam, C.S.1    Heersche, J.N.2    Murray, T.M.3
  • 11
    • 0035837553 scopus 로고    scopus 로고
    • Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis
    • Neer R.M., Arnaud C.D., Zanchetta J.R., et al. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med 2001, 344:1434-1441.
    • (2001) N Engl J Med , vol.344 , pp. 1434-1441
    • Neer, R.M.1    Arnaud, C.D.2    Zanchetta, J.R.3
  • 12
    • 0032746174 scopus 로고    scopus 로고
    • Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone
    • Jilka R.L., Weinstein R.S., Bellido T., et al. Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone. J Clin Invest 1999, 104:439-446.
    • (1999) J Clin Invest , vol.104 , pp. 439-446
    • Jilka, R.L.1    Weinstein, R.S.2    Bellido, T.3
  • 13
    • 58349093551 scopus 로고    scopus 로고
    • Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts
    • Jilka R.L., O'Brien C.A., Ali A.A., et al. Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts. Bone 2009, 44:275-286.
    • (2009) Bone , vol.44 , pp. 275-286
    • Jilka, R.L.1    O'Brien, C.A.2    Ali, A.A.3
  • 14
    • 0029116964 scopus 로고
    • Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells
    • Dobnig H., Turner R.T. Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells. Endocrinology 1995, 136:3632-3638.
    • (1995) Endocrinology , vol.136 , pp. 3632-3638
    • Dobnig, H.1    Turner, R.T.2
  • 15
    • 26844521277 scopus 로고    scopus 로고
    • Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis
    • Bellido T., Ali A.A., Gubrij I., et al. Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology 2005, 146:4577-4583.
    • (2005) Endocrinology , vol.146 , pp. 4577-4583
    • Bellido, T.1    Ali, A.A.2    Gubrij, I.3
  • 16
    • 77957853500 scopus 로고    scopus 로고
    • Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women
    • Drake M.T., Srinivasan B., Modder U.I., et al. Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. J Clin Endocrinol Metab 2010, 95:5056-5062.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 5056-5062
    • Drake, M.T.1    Srinivasan, B.2    Modder, U.I.3
  • 17
    • 84155188831 scopus 로고    scopus 로고
    • Update on Wnt signaling in bone cell biology and bone disease
    • Monroe D.G., McGee-Lawrence M.E., Oursler M.J., et al. Update on Wnt signaling in bone cell biology and bone disease. Gene 2012, 492:1-18.
    • (2012) Gene , vol.492 , pp. 1-18
    • Monroe, D.G.1    McGee-Lawrence, M.E.2    Oursler, M.J.3
  • 18
    • 0036708145 scopus 로고    scopus 로고
    • Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone
    • Bikle D.D., Sakata T., Leary C., et al. Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone. J Bone Miner Res 2002, 17:1570-1578.
    • (2002) J Bone Miner Res , vol.17 , pp. 1570-1578
    • Bikle, D.D.1    Sakata, T.2    Leary, C.3
  • 19
    • 0024536688 scopus 로고
    • Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone
    • McCarthy T.L., Centrella M., Canalis E. Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone. Endocrinology 1989, 124:1247-1253.
    • (1989) Endocrinology , vol.124 , pp. 1247-1253
    • McCarthy, T.L.1    Centrella, M.2    Canalis, E.3
  • 20
    • 0024552873 scopus 로고
    • Activation of the bone-derived latent TGF beta complex by isolated osteoclasts
    • Oreffo R.O., Mundy G.R., Seyedin S.M., et al. Activation of the bone-derived latent TGF beta complex by isolated osteoclasts. Biochem Biophys Res Commun 1989, 158:817-823.
    • (1989) Biochem Biophys Res Commun , vol.158 , pp. 817-823
    • Oreffo, R.O.1    Mundy, G.R.2    Seyedin, S.M.3
  • 21
    • 70350230386 scopus 로고    scopus 로고
    • Rapid and robust response of biochemical markers of bone formation to teriparatide therapy
    • Glover S.J., Eastell R., McCloskey E.V., et al. Rapid and robust response of biochemical markers of bone formation to teriparatide therapy. Bone 2009, 45:1053-1058.
    • (2009) Bone , vol.45 , pp. 1053-1058
    • Glover, S.J.1    Eastell, R.2    McCloskey, E.V.3
  • 22
    • 23744447531 scopus 로고    scopus 로고
    • Opposite bone remodeling effects of teriparatide and alendronate in increasing bone mass
    • McClung M.R., San Martin J., Miller P.D., et al. Opposite bone remodeling effects of teriparatide and alendronate in increasing bone mass. Arch Intern Med 2005, 165:1762-1768.
    • (2005) Arch Intern Med , vol.165 , pp. 1762-1768
    • McClung, M.R.1    San Martin, J.2    Miller, P.D.3
  • 23
    • 33947504500 scopus 로고    scopus 로고
    • Effect of recombinant human parathyroid hormone (1-84) on vertebral fracture and bone mineral density in postmenopausal women with osteoporosis: a randomized trial
    • Greenspan S.L., Bone H.G., Ettinger M.P., et al. Effect of recombinant human parathyroid hormone (1-84) on vertebral fracture and bone mineral density in postmenopausal women with osteoporosis: a randomized trial. Ann Intern Med 2007, 146:326-339.
    • (2007) Ann Intern Med , vol.146 , pp. 326-339
    • Greenspan, S.L.1    Bone, H.G.2    Ettinger, M.P.3
  • 24
    • 77951644239 scopus 로고    scopus 로고
    • Effects of teriparatide, alendronate, or both in women with postmenopausal osteoporosis
    • Finkelstein J.S., Wyland J.J., Lee H., et al. Effects of teriparatide, alendronate, or both in women with postmenopausal osteoporosis. J Clin Endocrinol Metab 2010, 95:1838-1845.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1838-1845
    • Finkelstein, J.S.1    Wyland, J.J.2    Lee, H.3
  • 25
    • 0141684971 scopus 로고    scopus 로고
    • The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis
    • Black D.M., Greenspan S.L., Ensrud K.E., et al. The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med 2003, 349:1207-1215.
    • (2003) N Engl J Med , vol.349 , pp. 1207-1215
    • Black, D.M.1    Greenspan, S.L.2    Ensrud, K.E.3
  • 26
    • 78649412131 scopus 로고    scopus 로고
    • Effects of intravenous zoledronic acid plus subcutaneous teriparatide [rhPTH(1-34)] in postmenopausal osteoporosis
    • Cosman F., Eriksen E.F., Recknor C., et al. Effects of intravenous zoledronic acid plus subcutaneous teriparatide [rhPTH(1-34)] in postmenopausal osteoporosis. J Bone Miner Res 2011, 26:503-511.
    • (2011) J Bone Miner Res , vol.26 , pp. 503-511
    • Cosman, F.1    Eriksen, E.F.2    Recknor, C.3
  • 27
    • 18644374464 scopus 로고    scopus 로고
    • A randomized double-blind trial to compare the efficacy of teriparatide [recombinant human parathyroid hormone (1-34)] with alendronate in postmenopausal women with osteoporosis
    • Body J.J., Gaich G.A., Scheele W.H., et al. A randomized double-blind trial to compare the efficacy of teriparatide [recombinant human parathyroid hormone (1-34)] with alendronate in postmenopausal women with osteoporosis. J Clin Endocrinol Metab 2002, 87:4528-4535.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4528-4535
    • Body, J.J.1    Gaich, G.A.2    Scheele, W.H.3
  • 28
    • 0242413030 scopus 로고    scopus 로고
    • Recombinant human parathyroid hormone (1-34) [teriparatide] improves both cortical and cancellous bone structure
    • Jiang Y., Zhao J.J., Mitlak B.H., et al. Recombinant human parathyroid hormone (1-34) [teriparatide] improves both cortical and cancellous bone structure. J Bone Miner Res 2003, 18:1932-1941.
    • (2003) J Bone Miner Res , vol.18 , pp. 1932-1941
    • Jiang, Y.1    Zhao, J.J.2    Mitlak, B.H.3
  • 29
    • 0034812187 scopus 로고    scopus 로고
    • Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: a paired biopsy study
    • Dempster D.W., Cosman F., Kurland E.S., et al. Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: a paired biopsy study. J Bone Miner Res 2001, 16:1846-1853.
    • (2001) J Bone Miner Res , vol.16 , pp. 1846-1853
    • Dempster, D.W.1    Cosman, F.2    Kurland, E.S.3
  • 30
    • 34248506476 scopus 로고    scopus 로고
    • Effects of a one-month treatment with PTH(1-34) on bone formation on cancellous, endocortical, and periosteal surfaces of the human ilium
    • Lindsay R., Zhou H., Cosman F., et al. Effects of a one-month treatment with PTH(1-34) on bone formation on cancellous, endocortical, and periosteal surfaces of the human ilium. J Bone Miner Res 2007, 22:495-502.
    • (2007) J Bone Miner Res , vol.22 , pp. 495-502
    • Lindsay, R.1    Zhou, H.2    Cosman, F.3
  • 31
    • 33144457259 scopus 로고    scopus 로고
    • A novel tetracycline labeling schedule for longitudinal evaluation of the short-term effects of anabolic therapy with a single iliac crest bone biopsy: early actions of teriparatide
    • Lindsay R., Cosman F., Zhou H., et al. A novel tetracycline labeling schedule for longitudinal evaluation of the short-term effects of anabolic therapy with a single iliac crest bone biopsy: early actions of teriparatide. J Bone Miner Res 2006, 21:366-373.
    • (2006) J Bone Miner Res , vol.21 , pp. 366-373
    • Lindsay, R.1    Cosman, F.2    Zhou, H.3
  • 32
    • 57449090596 scopus 로고    scopus 로고
    • Cancellous and cortical bone architecture and turnover at the iliac crest of postmenopausal osteoporotic women treated with parathyroid hormone 1-84
    • Recker R.R., Bare S.P., Smith S.Y., et al. Cancellous and cortical bone architecture and turnover at the iliac crest of postmenopausal osteoporotic women treated with parathyroid hormone 1-84. Bone 2009, 44:113-119.
    • (2009) Bone , vol.44 , pp. 113-119
    • Recker, R.R.1    Bare, S.P.2    Smith, S.Y.3
  • 33
    • 33845955242 scopus 로고    scopus 로고
    • Effects of teriparatide and alendronate on vertebral strength as assessed by finite element modeling of QCT scans in women with osteoporosis
    • Keaveny T.M., Donley D.W., Hoffmann P.F., et al. Effects of teriparatide and alendronate on vertebral strength as assessed by finite element modeling of QCT scans in women with osteoporosis. J Bone Miner Res 2007, 22:149-157.
    • (2007) J Bone Miner Res , vol.22 , pp. 149-157
    • Keaveny, T.M.1    Donley, D.W.2    Hoffmann, P.F.3
  • 34
    • 52949090528 scopus 로고    scopus 로고
    • Femoral bone strength and its relation to cortical and trabecular changes after treatment with PTH, alendronate, and their combination as assessed by finite element analysis of quantitative CT scans
    • Keaveny T.M., Hoffmann P.F., Singh M., et al. Femoral bone strength and its relation to cortical and trabecular changes after treatment with PTH, alendronate, and their combination as assessed by finite element analysis of quantitative CT scans. J Bone Miner Res 2008, 23:1974-1982.
    • (2008) J Bone Miner Res , vol.23 , pp. 1974-1982
    • Keaveny, T.M.1    Hoffmann, P.F.2    Singh, M.3
  • 35
    • 78651489838 scopus 로고    scopus 로고
    • Changes in trabecular and cortical bone microarchitecture at peripheral sites associated with 18 months of teriparatide therapy in postmenopausal women with osteoporosis
    • Macdonald H.M., Nishiyama K.K., Hanley D.A., et al. Changes in trabecular and cortical bone microarchitecture at peripheral sites associated with 18 months of teriparatide therapy in postmenopausal women with osteoporosis. Osteoporos Int 2011, 22:357-362.
    • (2011) Osteoporos Int , vol.22 , pp. 357-362
    • Macdonald, H.M.1    Nishiyama, K.K.2    Hanley, D.A.3
  • 36
    • 79960087488 scopus 로고    scopus 로고
    • Clinical practice. Glucocorticoid-induced bone disease
    • Weinstein R.S. Clinical practice. Glucocorticoid-induced bone disease. N Engl J Med 2011, 365:62-70.
    • (2011) N Engl J Med , vol.365 , pp. 62-70
    • Weinstein, R.S.1
  • 37
    • 36148958951 scopus 로고    scopus 로고
    • Teriparatide or alendronate in glucocorticoid-induced osteoporosis
    • Saag K.G., Shane E., Boonen S., et al. Teriparatide or alendronate in glucocorticoid-induced osteoporosis. N Engl J Med 2007, 357:2028-2039.
    • (2007) N Engl J Med , vol.357 , pp. 2028-2039
    • Saag, K.G.1    Shane, E.2    Boonen, S.3
  • 38
    • 0032532062 scopus 로고    scopus 로고
    • Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial
    • Lane N.E., Sanchez S., Modin G.W., et al. Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial. J Clin Invest 1998, 102:1627-1633.
    • (1998) J Clin Invest , vol.102 , pp. 1627-1633
    • Lane, N.E.1    Sanchez, S.2    Modin, G.W.3
  • 39
    • 0037214255 scopus 로고    scopus 로고
    • The effect of teriparatide [human parathyroid hormone (1-34)] therapy on bone density in men with osteoporosis
    • Orwoll E.S., Scheele W.H., Paul S., et al. The effect of teriparatide [human parathyroid hormone (1-34)] therapy on bone density in men with osteoporosis. J Bone Miner Res 2003, 18:9-17.
    • (2003) J Bone Miner Res , vol.18 , pp. 9-17
    • Orwoll, E.S.1    Scheele, W.H.2    Paul, S.3
  • 40
    • 22844447275 scopus 로고    scopus 로고
    • Teriparatide effects on vertebral fractures and bone mineral density in men with osteoporosis: treatment and discontinuation of therapy
    • Kaufman J.M., Orwoll E., Goemaere S., et al. Teriparatide effects on vertebral fractures and bone mineral density in men with osteoporosis: treatment and discontinuation of therapy. Osteoporos Int 2005, 16:510-516.
    • (2005) Osteoporos Int , vol.16 , pp. 510-516
    • Kaufman, J.M.1    Orwoll, E.2    Goemaere, S.3
  • 41
    • 0141796739 scopus 로고    scopus 로고
    • The effects of parathyroid hormone, alendronate, or both in men with osteoporosis
    • Finkelstein J.S., Hayes A., Hunzelman J.L., et al. The effects of parathyroid hormone, alendronate, or both in men with osteoporosis. N Engl J Med 2003, 349:1216-1226.
    • (2003) N Engl J Med , vol.349 , pp. 1216-1226
    • Finkelstein, J.S.1    Hayes, A.2    Hunzelman, J.L.3
  • 42
    • 0033710488 scopus 로고    scopus 로고
    • Parathyroid hormone as a therapy for idiopathic osteoporosis in men: effects on bone mineral density and bone markers
    • Kurland E.S., Cosman F., McMahon D.J., et al. Parathyroid hormone as a therapy for idiopathic osteoporosis in men: effects on bone mineral density and bone markers. J Clin Endocrinol Metab 2000, 85:3069-3076.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3069-3076
    • Kurland, E.S.1    Cosman, F.2    McMahon, D.J.3
  • 43
    • 79952707247 scopus 로고    scopus 로고
    • Time-dependent changes in skeletal response to teriparatide: escalating vs. constant dose teriparatide (PTH 1-34) in osteoporotic women
    • Yu E.W., Neer R.M., Lee H., et al. Time-dependent changes in skeletal response to teriparatide: escalating vs. constant dose teriparatide (PTH 1-34) in osteoporotic women. Bone 2011, 48:713-719.
    • (2011) Bone , vol.48 , pp. 713-719
    • Yu, E.W.1    Neer, R.M.2    Lee, H.3
  • 44
    • 45149119618 scopus 로고    scopus 로고
    • Randomized trial of once-weekly parathyroid hormone (1-84) on bone mineral density and remodeling
    • Black D.M., Bouxsein M.L., Palermo L., et al. Randomized trial of once-weekly parathyroid hormone (1-84) on bone mineral density and remodeling. J Clin Endocrinol Metab 2008, 93:2166-2172.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2166-2172
    • Black, D.M.1    Bouxsein, M.L.2    Palermo, L.3
  • 45
    • 23444435838 scopus 로고    scopus 로고
    • Daily and cyclic parathyroid hormone in women receiving alendronate
    • Cosman F., Nieves J., Zion M., et al. Daily and cyclic parathyroid hormone in women receiving alendronate. N Engl J Med 2005, 353:566-575.
    • (2005) N Engl J Med , vol.353 , pp. 566-575
    • Cosman, F.1    Nieves, J.2    Zion, M.3
  • 46
    • 67650254286 scopus 로고    scopus 로고
    • Effects of teriparatide retreatment in osteoporotic men and women
    • Finkelstein J.S., Wyland J.J., Leder B.Z., et al. Effects of teriparatide retreatment in osteoporotic men and women. J Clin Endocrinol Metab 2009, 94:2495-2501.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 2495-2501
    • Finkelstein, J.S.1    Wyland, J.J.2    Leder, B.Z.3
  • 47
    • 66349091315 scopus 로고    scopus 로고
    • Retreatment with teriparatide one year after the first teriparatide course in patients on continued long-term alendronate
    • Cosman F., Nieves J.W., Zion M., et al. Retreatment with teriparatide one year after the first teriparatide course in patients on continued long-term alendronate. J Bone Miner Res 2009, 24:1110-1115.
    • (2009) J Bone Miner Res , vol.24 , pp. 1110-1115
    • Cosman, F.1    Nieves, J.W.2    Zion, M.3
  • 48
    • 75149140424 scopus 로고    scopus 로고
    • Effect of transdermal teriparatide administration on bone mineral density in postmenopausal women
    • Cosman F., Lane N.E., Bolognese M.A., et al. Effect of transdermal teriparatide administration on bone mineral density in postmenopausal women. J Clin Endocrinol Metab 2010, 95:151-158.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 151-158
    • Cosman, F.1    Lane, N.E.2    Bolognese, M.A.3
  • 49
    • 33748636445 scopus 로고    scopus 로고
    • Daily nasal spray of hPTH(1-34) for 3 months increases bone mass in osteoporotic subjects: a pilot study
    • Matsumoto T., Shiraki M., Hagino H., et al. Daily nasal spray of hPTH(1-34) for 3 months increases bone mass in osteoporotic subjects: a pilot study. Osteoporos Int 2006, 17:1532-1538.
    • (2006) Osteoporos Int , vol.17 , pp. 1532-1538
    • Matsumoto, T.1    Shiraki, M.2    Hagino, H.3
  • 50
    • 0030804947 scopus 로고    scopus 로고
    • Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis
    • Lindsay R., Nieves J., Formica C., et al. Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis. Lancet 1997, 350:550-555.
    • (1997) Lancet , vol.350 , pp. 550-555
    • Lindsay, R.1    Nieves, J.2    Formica, C.3
  • 51
    • 0035063315 scopus 로고    scopus 로고
    • Parathyroid hormone added to established hormone therapy: effects on vertebral fracture and maintenance of bone mass after parathyroid hormone withdrawal
    • Cosman F., Nieves J., Woelfert L., et al. Parathyroid hormone added to established hormone therapy: effects on vertebral fracture and maintenance of bone mass after parathyroid hormone withdrawal. J Bone Miner Res 2001, 16:925-931.
    • (2001) J Bone Miner Res , vol.16 , pp. 925-931
    • Cosman, F.1    Nieves, J.2    Woelfert, L.3
  • 52
    • 33144473937 scopus 로고    scopus 로고
    • Effect of teriparatide [rhPTH(1-34)] on BMD when given to postmenopausal women receiving hormone replacement therapy
    • Ste-Marie L.G., Schwartz S.L., Hossain A., et al. Effect of teriparatide [rhPTH(1-34)] on BMD when given to postmenopausal women receiving hormone replacement therapy. J Bone Miner Res 2006, 21:283-291.
    • (2006) J Bone Miner Res , vol.21 , pp. 283-291
    • Ste-Marie, L.G.1    Schwartz, S.L.2    Hossain, A.3
  • 53
    • 27444444044 scopus 로고    scopus 로고
    • Combination teriparatide and raloxifene therapy for postmenopausal osteoporosis: results from a 6-month double-blind placebo-controlled trial
    • Deal C., Omizo M., Schwartz E.N., et al. Combination teriparatide and raloxifene therapy for postmenopausal osteoporosis: results from a 6-month double-blind placebo-controlled trial. J Bone Miner Res 2005, 20:1905-1911.
    • (2005) J Bone Miner Res , vol.20 , pp. 1905-1911
    • Deal, C.1    Omizo, M.2    Schwartz, E.N.3
  • 54
    • 33747682160 scopus 로고    scopus 로고
    • Effects of teriparatide, alendronate, or both on bone turnover in osteoporotic men
    • Finkelstein J.S., Leder B.Z., Burnett S.M., et al. Effects of teriparatide, alendronate, or both on bone turnover in osteoporotic men. J Clin Endocrinol Metab 2006, 91:2882-2887.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 2882-2887
    • Finkelstein, J.S.1    Leder, B.Z.2    Burnett, S.M.3
  • 55
    • 70349897684 scopus 로고    scopus 로고
    • Effects of teriparatide in postmenopausal women with osteoporosis on prior alendronate or raloxifene: differences between stopping and continuing the antiresorptive agent
    • Cosman F., Wermers R.A., Recknor C., et al. Effects of teriparatide in postmenopausal women with osteoporosis on prior alendronate or raloxifene: differences between stopping and continuing the antiresorptive agent. J Clin Endocrinol Metab 2009, 94:3772-3780.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3772-3780
    • Cosman, F.1    Wermers, R.A.2    Recknor, C.3
  • 56
    • 3242762388 scopus 로고    scopus 로고
    • Differential effects of teriparatide on BMD after treatment with raloxifene or alendronate
    • Ettinger B., San Martin J., Crans G., et al. Differential effects of teriparatide on BMD after treatment with raloxifene or alendronate. J Bone Miner Res 2004, 19:745-751.
    • (2004) J Bone Miner Res , vol.19 , pp. 745-751
    • Ettinger, B.1    San Martin, J.2    Crans, G.3
  • 57
    • 52949131857 scopus 로고    scopus 로고
    • Effects of two years of daily teriparatide treatment on BMD in postmenopausal women with severe osteoporosis with and without prior antiresorptive treatment
    • Obermayer-Pietsch B.M., Marin F., McCloskey E.V., et al. Effects of two years of daily teriparatide treatment on BMD in postmenopausal women with severe osteoporosis with and without prior antiresorptive treatment. J Bone Miner Res 2008, 23:1591-1600.
    • (2008) J Bone Miner Res , vol.23 , pp. 1591-1600
    • Obermayer-Pietsch, B.M.1    Marin, F.2    McCloskey, E.V.3
  • 58
    • 79955987629 scopus 로고    scopus 로고
    • Early changes in biochemical markers of bone turnover and their relationship with bone mineral density changes after 24 months of treatment with teriparatide
    • Blumsohn A., Marin F., Nickelsen T., et al. Early changes in biochemical markers of bone turnover and their relationship with bone mineral density changes after 24 months of treatment with teriparatide. Osteoporos Int 2011, 22:1935-1946.
    • (2011) Osteoporos Int , vol.22 , pp. 1935-1946
    • Blumsohn, A.1    Marin, F.2    Nickelsen, T.3
  • 59
    • 53749105039 scopus 로고    scopus 로고
    • Early responsiveness of women with osteoporosis to teriparatide after therapy with alendronate or risedronate
    • Miller P.D., Delmas P.D., Lindsay R., et al. Early responsiveness of women with osteoporosis to teriparatide after therapy with alendronate or risedronate. J Clin Endocrinol Metab 2008, 93:3785-3793.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3785-3793
    • Miller, P.D.1    Delmas, P.D.2    Lindsay, R.3
  • 60
    • 0034458020 scopus 로고    scopus 로고
    • Enhancement of bone mass in osteoporotic women with parathyroid hormone followed by alendronate
    • Rittmaster R.S., Bolognese M., Ettinger M.P., et al. Enhancement of bone mass in osteoporotic women with parathyroid hormone followed by alendronate. J Clin Endocrinol Metab 2000, 85:2129-2134.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2129-2134
    • Rittmaster, R.S.1    Bolognese, M.2    Ettinger, M.P.3
  • 61
    • 6344278780 scopus 로고    scopus 로고
    • Sustained vertebral fracture risk reduction after withdrawal of teriparatide in postmenopausal women with osteoporosis
    • Lindsay R., Scheele W.H., Neer R., et al. Sustained vertebral fracture risk reduction after withdrawal of teriparatide in postmenopausal women with osteoporosis. Arch Intern Med 2004, 164:2024-2030.
    • (2004) Arch Intern Med , vol.164 , pp. 2024-2030
    • Lindsay, R.1    Scheele, W.H.2    Neer, R.3
  • 62
    • 23444452077 scopus 로고    scopus 로고
    • One year of alendronate after one year of parathyroid hormone (1-84) for osteoporosis
    • Black D.M., Bilezikian J.P., Ensrud K.E., et al. One year of alendronate after one year of parathyroid hormone (1-84) for osteoporosis. N Engl J Med 2005, 353:555-565.
    • (2005) N Engl J Med , vol.353 , pp. 555-565
    • Black, D.M.1    Bilezikian, J.P.2    Ensrud, K.E.3
  • 63
    • 0036001310 scopus 로고    scopus 로고
    • Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1-34) for 2 years and relevance to human safety
    • Vahle J.L., Sato M., Long G.G., et al. Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1-34) for 2 years and relevance to human safety. Toxicol Pathol 2002, 30:312-321.
    • (2002) Toxicol Pathol , vol.30 , pp. 312-321
    • Vahle, J.L.1    Sato, M.2    Long, G.G.3
  • 64
    • 0036721125 scopus 로고    scopus 로고
    • Abnormal bone architecture and biomechanical properties with near-lifetime treatment of rats with PTH
    • Sato M., Vahle J., Schmidt A., et al. Abnormal bone architecture and biomechanical properties with near-lifetime treatment of rats with PTH. Endocrinology 2002, 143:3230-3242.
    • (2002) Endocrinology , vol.143 , pp. 3230-3242
    • Sato, M.1    Vahle, J.2    Schmidt, A.3
  • 65
    • 3242887547 scopus 로고    scopus 로고
    • Bone neoplasms in F344 rats given teriparatide [rhPTH(1-34)] are dependent on duration of treatment and dose
    • Vahle J.L., Long G.G., Sandusky G., et al. Bone neoplasms in F344 rats given teriparatide [rhPTH(1-34)] are dependent on duration of treatment and dose. Toxicol Pathol 2004, 32:426-438.
    • (2004) Toxicol Pathol , vol.32 , pp. 426-438
    • Vahle, J.L.1    Long, G.G.2    Sandusky, G.3
  • 66
    • 33845769891 scopus 로고    scopus 로고
    • Defining a noncarcinogenic dose of recombinant human parathyroid hormone 1-84 in a 2-year study in Fischer 344 rats
    • Jolette J., Wilker C.E., Smith S.Y., et al. Defining a noncarcinogenic dose of recombinant human parathyroid hormone 1-84 in a 2-year study in Fischer 344 rats. Toxicol Pathol 2006, 34:929-940.
    • (2006) Toxicol Pathol , vol.34 , pp. 929-940
    • Jolette, J.1    Wilker, C.E.2    Smith, S.Y.3
  • 67
    • 56749181173 scopus 로고    scopus 로고
    • Lack of bone neoplasms and persistence of bone efficacy in cynomolgus macaques after long-term treatment with teriparatide [rhPTH(1-34)]
    • Vahle J.L., Zuehlke U., Schmidt A., et al. Lack of bone neoplasms and persistence of bone efficacy in cynomolgus macaques after long-term treatment with teriparatide [rhPTH(1-34)]. J Bone Miner Res 2008, 23:2033-2039.
    • (2008) J Bone Miner Res , vol.23 , pp. 2033-2039
    • Vahle, J.L.1    Zuehlke, U.2    Schmidt, A.3
  • 69
    • 77954553687 scopus 로고    scopus 로고
    • Of mice and men: divergent risks of teriparatide-induced osteosarcoma
    • Subbiah V., Madsen V.S., Raymond A.K., et al. Of mice and men: divergent risks of teriparatide-induced osteosarcoma. Osteoporos Int 2010, 21:1041-1045.
    • (2010) Osteoporos Int , vol.21 , pp. 1041-1045
    • Subbiah, V.1    Madsen, V.S.2    Raymond, A.K.3
  • 70
    • 38849178302 scopus 로고    scopus 로고
    • Building bone to reverse osteoporosis and repair fractures
    • Khosla S., Westendorf J.J., Oursler M.J. Building bone to reverse osteoporosis and repair fractures. J Clin Invest 2008, 118:421-428.
    • (2008) J Clin Invest , vol.118 , pp. 421-428
    • Khosla, S.1    Westendorf, J.J.2    Oursler, M.J.3
  • 71
    • 84862248680 scopus 로고    scopus 로고
    • Sclerostin: therapeutic horizons based upon its actions
    • Costa A.G., Bilezikian J.P. Sclerostin: therapeutic horizons based upon its actions. Curr Osteoporos Rep 2012, 10:64-72.
    • (2012) Curr Osteoporos Rep , vol.10 , pp. 64-72
    • Costa, A.G.1    Bilezikian, J.P.2
  • 72
    • 44449099165 scopus 로고    scopus 로고
    • Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
    • Li X., Ominsky M.S., Niu Q.T., et al. Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. J Bone Miner Res 2008, 23:860-869.
    • (2008) J Bone Miner Res , vol.23 , pp. 860-869
    • Li, X.1    Ominsky, M.S.2    Niu, Q.T.3
  • 73
    • 65549152230 scopus 로고    scopus 로고
    • Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis
    • Li X., Ominsky M.S., Warmington K.S., et al. Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis. J Bone Miner Res 2009, 24:578-588.
    • (2009) J Bone Miner Res , vol.24 , pp. 578-588
    • Li, X.1    Ominsky, M.S.2    Warmington, K.S.3
  • 74
    • 77953481395 scopus 로고    scopus 로고
    • Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
    • Ominsky M.S., Vlasseros F., Jolette J., et al. Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength. J Bone Miner Res 2010, 25:948-959.
    • (2010) J Bone Miner Res , vol.25 , pp. 948-959
    • Ominsky, M.S.1    Vlasseros, F.2    Jolette, J.3
  • 75
    • 79955635177 scopus 로고    scopus 로고
    • Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of non-fractured bones
    • Ominsky M.S., Li C., Li X., et al. Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of non-fractured bones. J Bone Miner Res 2010, 26:1012-1021.
    • (2010) J Bone Miner Res , vol.26 , pp. 1012-1021
    • Ominsky, M.S.1    Li, C.2    Li, X.3
  • 76
    • 80052478948 scopus 로고    scopus 로고
    • Increased bone formation and bone mass induced by sclerostin antibody is not affected by pretreatment or cotreatment with alendronate in osteopenic, ovariectomized rats
    • Li X., Ominsky M.S., Warmington K.S., et al. Increased bone formation and bone mass induced by sclerostin antibody is not affected by pretreatment or cotreatment with alendronate in osteopenic, ovariectomized rats. Endocrinology 2011, 152:3312-3322.
    • (2011) Endocrinology , vol.152 , pp. 3312-3322
    • Li, X.1    Ominsky, M.S.2    Warmington, K.S.3
  • 77
    • 78650958526 scopus 로고    scopus 로고
    • Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
    • Padhi D., Jang G., Stouch B., et al. Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody. J Bone Miner Res 2011, 26:19-26.
    • (2011) J Bone Miner Res , vol.26 , pp. 19-26
    • Padhi, D.1    Jang, G.2    Stouch, B.3
  • 78
    • 33646856033 scopus 로고    scopus 로고
    • Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass
    • Morvan F., Boulukos K., Clement-Lacroix P., et al. Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass. J Bone Miner Res 2006, 21:934-945.
    • (2006) J Bone Miner Res , vol.21 , pp. 934-945
    • Morvan, F.1    Boulukos, K.2    Clement-Lacroix, P.3
  • 79
    • 33846025409 scopus 로고    scopus 로고
    • Knocking down dickkopf-1 alleviates estrogen deficiency induction of bone loss. A histomorphological study in ovariectomized rats
    • Wang F.S., Ko J.Y., Lin C.L., et al. Knocking down dickkopf-1 alleviates estrogen deficiency induction of bone loss. A histomorphological study in ovariectomized rats. Bone 2007, 40:485-492.
    • (2007) Bone , vol.40 , pp. 485-492
    • Wang, F.S.1    Ko, J.Y.2    Lin, C.L.3
  • 80
    • 77949739818 scopus 로고    scopus 로고
    • The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf-1 antibody for osteoporosis
    • Betts A.M., Clark T.H., Yang J., et al. The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf-1 antibody for osteoporosis. J Pharmacol Exp Ther 2010, 333:2-13.
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 2-13
    • Betts, A.M.1    Clark, T.H.2    Yang, J.3
  • 81
    • 0037323386 scopus 로고    scopus 로고
    • Short-term, high-dose parathyroid hormone-related protein as a skeletal anabolic agent for the treatment of postmenopausal osteoporosis
    • Horwitz M.J., Tedesco M.B., Gundberg C., et al. Short-term, high-dose parathyroid hormone-related protein as a skeletal anabolic agent for the treatment of postmenopausal osteoporosis. J Clin Endocrinol Metab 2003, 88:569-575.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 569-575
    • Horwitz, M.J.1    Tedesco, M.B.2    Gundberg, C.3


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