Effects of a combination of ketanserin and propranolol on inflammatory hyperalgesia in rats

European Journal of Pharmacology

Volumn 721, Issue 1-3, 2013, Pages 126-132

  Wang, Dongmei ^a   Zhou, Xiaolong ^a   Hong, Yanguo ^a  

^a FUJIAN NORMAL UNIVERSITY   (China)

Author keywords

5 HT1A receptors; 5 HT2A receptors; Inflammatory hyperalgesia; Ketanserin; Peripheral pain mechanism; Propranolol

Indexed keywords

17 METHYLNALOXONE; CARRAGEENAN; KETANSERIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NALOXONE; PROPRANOLOL; SEROTONIN RECEPTOR;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; HYPERALGESIA; INFLAMMATORY HYPERALGESIA; MALE; MYALGIA; NOCICEPTIVE STIMULATION; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT;

5-HT(1A) RECEPTORS; 5-HT(2A) RECEPTORS; INFLAMMATORY HYPERALGESIA; KETANSERIN; PERIPHERAL PAIN MECHANISM; PROPRANOLOL;

ANALGESICS; ANIMALS; ARTHRITIS; CARRAGEENAN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HYPERALGESIA; INFLAMMATION; KETANSERIN; MALE; MYALGIA; PIPERAZINES; PROPRANOLOL; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84890116350     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.09.043     Document Type: Article

References (43)

1. F. Aricioglu, U. Buldanlioglu, G. Salanturoglu, and N.S. Ozyalcin Evaluation of antinociceptive and anti-inflammatory effects of venlafaxine in the rat Agriculture 17 2005 41 46
2. B. Bannwarth Risk-benefit assessment of opioids in chronic noncancer pain Drug Safety 21 1999 283 296 (Pubitemid 29465696)
3. L. Bardin, J. Schmidt, A. Alloui, and A. Eschalier Effect of intrathecal administration of serotonin in chronic pain models in rats European Journal of Pharmacology 409 2000 37 43
4. R. Benyamin, A.M. Trescot, S. Datta, R. Buenaventura, R. Adlaka, N. Sehgal, S.E. Glaser, and R. Vallejo Opioid complications and side effects Pain Physician 11 2008 S105 S120
5. S.M. Carlton, and R.E. Coggeshall Immunohistochemical localization of 5-HT2A receptors in peripheral sensory axons in rat glabrous skin Brain Research 763 1997 271 275 (Pubitemid 27364450)
6. L.E. Chaparro, P.J. Wiffen, R.A. Moore, and I. Gilron Combination pharmacotherapy for the treatment of neuropathic pain in adults Cochrane Database of Systematic Reviews 7 2012 CD008943
7. T.J. Coderre, and P.D. Wall Ankle joint urate arthritis in rats provides a useful tool for the evaluation of analgesic and anti-arthritic agents Pharmacology Biochemistry and Behavior 29 1988 461 466 (Pubitemid 19256802)
8. T. Crisp, J.L. Stafinsky, L.J. Spanos, M. Uram, V.C. Perni, and H.B. Donepudi Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord General Pharmacology 22 1991 247 251
9. M. Di Rosa, and D.A. Willoughby Screens for anti-inflammatory drugs Journal of Pharmacy and Pharmacology 23 1971 297 298
10. M. Ernberg, T. Lundeberg, and S. Kopp Effect of propranolol and granisetron on experimentally induced pain and allodynia/hyperalgesia by intramuscular injection of serotonin into the human masseter muscle Pain 84 2000 339 346 (Pubitemid 30074236)
11. J.P. Estebe, M.E. Gentili, C.P. Le, V.R. Le, J.P. Moulinoux, and C. Ecoffey Sciatic nerve block with bupivacaine-loaded microspheres prevents hyperalgesia in an inflammatory animal model Canadian Journal of Anesthesia 49 2002 690 693 (Pubitemid 35203672)
12. C.A. Fornal, C.W. Metzler, R.A. Gallegos, S.C. Veasey, A.C. McCreary, and B.L. Jacobs WAY-100635, a potent and selective 5-hydroxytryptamine1A antagonist, increases serotonergic neuronal activity in behaving cats: comparison with (S)-WAY-100135 Journal of Pharmacological and Experimental Therapy 278 1996 752 762
13. D.S. Franca, D.L. Ferreira-Alves, I.D. Duarte, M.C. Ribeiro, R.M. Rezende, Y.S. Bakhle, and J.N. Francischi Endogenous opioids mediate the hypoalgesia induced by selective inhibitors of cyclo-oxygenase 2 in rat paws treated with carrageenan Neuropharmacology 51 2006 37 43 (Pubitemid 44192398)
14. I. Gilron, and M.B. Max Combination pharmacotherapy for neuropathic pain: current evidence and future directions Expert Review of Neurotherapeutics 5 2005 823 830 (Pubitemid 41679649)
15. Y. Hong, H. Ji, and H. Wei Topical ketanserin attenuates hyperalgesia and inflammation in arthritis in rats Pain 124 2006 27 33 (Pubitemid 44176190)
16. A.K. Houghton, Y. Lu, and K.N. Westlund S-(+)-3-isobutylgaba and its stereoisomer reduces the amount of inflammation and hyperalgesia in an acute arthritis model in the rat Journal of Pharmacology and Experimental Therapeutics 285 1998 533 538 (Pubitemid 28237429)
17. D. Hoyer, J.P. Hannon, and G.R. Martin Molecular, pharmacological and functional diversity of 5-HT receptors Pharmacology Biochemistry and Behavior 71 2002 533 554 (Pubitemid 34219205)
18. J. Huang, Q. Cai, Y. Chen, and Y. Hong Treatment with ketanserin produces opioid-mediated hypoalgesia in the late phase of carrageenan-induced inflammatory hyperalgesia in rats Brain Research 1303 2009 39 47
19. 2A receptors inhibits the expression of pronociceptive mediator and enhances endogenous opioid mechanism in carrageenan-induced inflammation in rats European Journal of Pharmacology 633 2011 39 47
20. W.A. Katz Use of nonopioid analgesics and adjunctive agents in the management of pain in rheumatic diseases Current Opinion in Rheumatology 14 2002 63 71 (Pubitemid 34059892)
21. V. Kayser, and G. Guilbaud Physiological relevance and time course of a tonic endogenous opioid modulation of nociceptive messages, based on the effects of naloxone in a rat model of localized hyperalgesic inflammation Brain Research 567 1991 197 203
22. A.M. Laporte, C.M. Fattaccini, M.C. Lombard, J. Chauveau, and M. Hamon Effects of dorsal rhizotomy and selective lesion of serotonergic and noradrenergic systems on 5-HT1A, 5-HT1B, and 5-HT3 receptors in the rat spinal cord Journal of Neural Transmission General Section. 100 1995 207 223
23. X.Y. Liu, S.X. Wu, Y.Y. Wang, W. Wang, L. Zhou, and Y.Q. Li Changes of 5-HT receptor subtype mRNAs in rat dorsal root ganglion by bee venom-induced inflammatory pain Neuroscience Letters 375 2005 42 46 (Pubitemid 40139065)
24. H. Machelska, J.K. Schopohl, S.A. Mousa, D. Labuz, M. Schafer, and C. Stein Different mechanisms of intrinsic pain inhibition in early and late inflammation Journal of Neuroimmunology 141 2003 30 39 (Pubitemid 37288994)
25. T. Maeshima, R. Ito, S. Hamada, K. Senzaki, K. Hamaguchi-Hamada, F. Shutoh, and N. Okado The cellular localization of 5-HT2A receptors in the spinal cord and spinal ganglia of the adult rat Brain Research 797 1998 118 124 (Pubitemid 28331496)
26. J.C. Martel, M.B. Assie, L. Bardin, R. Depoortere, D. Cussac, and A. Newman-Tancredi 5-HT1A receptors are involved in the effects of xaliproden on G-protein activation, neurotransmitter release and nociception British Journal of Pharmacology 158 2009 232 242
27. G. Maura, E. Roccatagliata, and M. Raiteri Serotonin autoreceptor in rat hippocampus: pharmacological characterization as a subtype of the 5-HT1 receptor Naunyn-Schmiedeberg's Archives of Pharmacology 334 1986 323 326 (Pubitemid 17056372)
28. R.J. Milne, J.M. Coddington, and G.D. Gamble Quaternary naloxone blocks morphine analgesia in spinal but not intact rats Neuroscience Letters 114 1990 259 264 (Pubitemid 20205145)
29. M.K. Mundey, A. Fletcher, and C.A. Marsden Effects of 8-OHDPAT and 5-HT1A antagonists WAY100135 and WAY100635, on guinea-pig behaviour and dorsal raphe 5-HT neurone firing British Journa of Pharmacology 117 1996 750 756
30. K. Okamoto, H. Imbe, Y. Morikawa, M. Itoh, M. Sekimoto, K. Nemoto, and E. Senba 5-HT2A receptor subtype in the peripheral branch of sensory fibers is involved in the potentiation of inflammatory pain in rats Pain 99 2002 133 143 (Pubitemid 35247536)
31. C.A. Parada, C.H. Tambeli, F.Q. Cunha, and S.H. Ferreira The major role of peripheral release of histamine and 5-hydroxytryptamine in formalin-induced nociception Neuroscience 102 2001 937 944 (Pubitemid 32155888)
32. M.A. Pozo, E.A. Balazs, and C. Belmonte Reduction of sensory responses to passive movements of inflamed knee joints by hylan, a hyaluronan derivative Experimental Brain Research 116 1997 3 9 (Pubitemid 27359190)
33. H.G. Schaible, and R.F. Schmidt Effects of an experimental arthritis on the sensory properties of fine articular afferent units Journal of Neurophysiology 54 1985 1109 1122 (Pubitemid 16210106)
34. P. Schweinhardt, Y.B. Abulhasan, V. Koeva, T. Balderi, D.J. Kim, M. Alhujairi, and F. Carli Effects of intravenous propranolol on heat pain sensitivity in healthy men European Journal of Pain 17 2013 704 713
35. K.A. Sluka Blockade of N- and P/Q-type calcium channels reduces the secondary heat hyperalgesia induced by acute inflammation Journal of Pharmacology and Experimental Therapeutics. 287 1998 232 237 (Pubitemid 29140206)
36. K.A. Sluka, K. Bailey, J. Bogush, R. Olson, and A. Ricketts Treatment with either high or low frequency TENS reduces the secondary hyperalgesia observed after injection of kaolin and carrageenan into the knee joint Pain 77 1998 97 102 (Pubitemid 28398839)
37. K.A. Sluka, J.J. Rohlwing, R.A. Bussey, S.A. Eikenberry, and J.M. Wilken Chronic muscle pain induced by repeated acid Injection is reversed by spinally administered mu- and delta-, but not kappa-, opioid receptor agonists Journal of Pharmacology and Experimental Therapeutics 302 2002 1146 1150 (Pubitemid 34920237)
38. Z. Song, B.A. Meyerson, and B. Linderoth Spinal 5-HT receptors that contribute to the pain-relieving effects of spinal cord stimulation in a rat model of neuropathy Pain 152 2011 1666 1673
39. H.J. van de Wal, P.F. Wijn, H.J. van Lier, and S.H. Skotnicki The effectiveness of ketanserin in patients with primary Raynaud's phenomenon. A randomized, double blind, placebo controlled study International Angiology 6 1987 313 322 (Pubitemid 18038748)
40. P. Varamini, F.M. Mansfeld, J.T. Blanchfield, B.D. Wyse, M.T. Smith, and I. Toth Lipo-endomorphin-1 derivatives with systemic activity against neuropathic pain without producing constipation PLoS.One. 7 2012 e41909
41. H. Wei, Y. Chen, and Y. Hong The contribution of peripheral 5-hydroxytryptamine2A receptor to carrageenan-evoked hyperalgesia, inflammation and spinal Fos protein expression in the rat Neuroscience 132 2005 1073 1082 (Pubitemid 40602541)
42. Z. Zeino, G. Sisson, and I. Bjarnason Adverse effects of drugs on small intestine and colon Best Practice & Research Clinical Gastroenterology 24 2010 133 141
43. L. Zhang, Y. Lu, Y. Chen, and K.N. Westlund Group I metabotropic glutamate receptor antagonists block secondary thermal hyperalgesia in rats with knee joint inflammation Journal of Pharmacology and Experimental Therapeutics 300 2002 149 156 (Pubitemid 34028521)