Lemon grass (Cymbopogon citratus (D.C) Stapf) polyphenols protect human umbilical vein endothelial cell (HUVECs) from oxidative damage induced by high glucose, hydrogen peroxide and oxidised low-density lipoprotein

Food Chemistry

Volumn 151, Issue , 2014, Pages 175-181

  Campos, J ^a,b,c   Schmeda Hirschmann, G ^b   Leiva, E ^b   Guzman L ^b   Orrego, R ^b   Fernandez P ^a   Gonzalez M ^a   Radojkovic, C ^a   Zuniga F A ^a   Lamperti, L ^a   Pastene, E ^a   Aguayo, C ^a  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

^b UNIVERSIDAD DE TALCA   (Chile)

^c UNIVERSIDAD SAN SEBASTIÁN   (Chile)

Author keywords

Atherosclerosis; Cymbopogon citratus; Endothelial dysfunction; Nitric oxide; Oxidative stress

Indexed keywords

ANTIOXIDANTS; BLOOD VESSELS; CHROMATOGRAPHY; CITRUS FRUITS; ENDOTHELIAL CELLS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN PEROXIDE; LIPOPROTEINS; MASS SPECTROMETRY; NITRIC OXIDE; OXIDATIVE STRESS; PEROXIDES;

ANTIOXIDANT PROPERTIES; ATHEROSCLEROSIS; CHROMATOGRAPHIC PROCEDURE; CYMBOPOGON CITRATUS; ENDOTHELIAL DYSFUNCTION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; LOW DENSITY LIPOPROTEINS; REACTIVE OXIDATIVE SPECIES;

OXIDATION;

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; APIGENIN; ASCORBIC ACID; CHLOROGENIC ACID; COPPER; CYMBOPOGON CITRATUS EXTRACT; FLAVONOID GLYCOSIDE; GLUCOSE; HYDROGEN PEROXIDE; ISOORIENTIN; LUTEOLIN; NITRIC OXIDE; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; REACTIVE OXYGEN METABOLITE; SWERTIAJAPONIN; UNCLASSIFIED DRUG; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PLANT EXTRACT; POLYPHENOL;

ANTIOXIDANT ACTIVITY; ARTICLE; BIOAVAILABILITY; CELL PROTECTION; CONTROLLED STUDY; DIODE; DRUG EFFECT; DRUG IDENTIFICATION; ENDOTHELIAL DYSFUNCTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MASS SPECTROMETRY; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE STRESS; UMBILICAL VEIN ENDOTHELIAL CELL; VASOCONSTRICTION; VASODILATATION; CHEMISTRY; CYMBOPOGON; METABOLISM; OXIDATION REDUCTION REACTION;

CYMBOPOGON CITRATUS;

CYMBOPOGON; GLUCOSE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; LIPOPROTEINS, LDL; OXIDATION-REDUCTION; PLANT EXTRACTS; POLYPHENOLS; REACTIVE OXYGEN SPECIES;

EID: 84890101208     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.11.018     Document Type: Article

References (46)

1. H.Y. Ahn, and C.H. Kim Epigallocatechin-3-gallate regulates inducible nitric oxide synthase expression in human umbilical vein endothelial cells Laboratory of Animal Research 27 2 2011 85 90
2. M. Akagawa, T. Shigemitsu, and K. Suyama Production of hydrogen peroxide by polyphenols and polyphenol-rich beverages under quasi-physiological conditions Bioscience, Biotechnology, and Biochemistry 67 12 2003 2632 2640 (Pubitemid 39251617)
3. A. Andrade-Cetto, and H. Wiedenfeld Hypoglycemic effect of Cecropia obtusifolia on streptozotocin diabetic rats Journal of Ethnopharmacology 78 2-3 2001 145 149 (Pubitemid 32994783)
4. H. Aoshima, and S. Ayabe Prevention of the deterioration of polyphenol-rich beverages Food Chemistry 100 1 2007 350 355
5. T.F. Bachiega, and J.M. Sforcin Lemon grass and citral effect on cytokines production by murine macrophages Journal of Ethnopharmacology 137 1 2011 909 913
6. J.F. Bastos, I.J. Moreira, T.P. Ribeiro, I.A. Medeiros, A.R. Antoniolli, D.P. De Sousa, and M.R. Santos Hypotensive and vasorelaxant effects of citronellol, a monoterpene alcohol, in rats Basic & Clinical Pharmacology & Toxicology 106 4 2010 331 337
7. P. Bellion, M. Olk, F. Will, H. Dietrich, M. Baum, G. Eisenbrand, and C. Janzowski Formation of hydrogen peroxide in cell culture media by apple polyphenols and its effect on antioxidant biomarkers in the colon cell line HT-29 Molecular Nutrition & Food Research 53 10 2009 1226 1236
8. G. Booth, T.J. Stalker, A.M. Lefer, and R. Scalia Mechanisms of amelioration of glucose-induced endothelial dysfunction following inhibition of protein kinase C in vivo Diabetes 51 5 2002 1556 1564 (Pubitemid 34826625)
9. A.E. Caballero Endothelial dysfunction in obesity and insulin resistance. A road to diabetes and heart disease Obesity Research 11 11 2003 1278 1289 (Pubitemid 41127348)
10. C. Carru, A. Zinellu, F. Galistu, M. Barca, V. Pasciu, F. Lumbau, B. Sanna, B. Tadolini, and L. Deiana The evaluation of the oxidative state of native-LDL: Three methods compared Journal of Biochemical and Biophysical Methods 61 3 2004 271 281 (Pubitemid 39574942)
11. J. Cheel, C. Theoduloz, J. Rodriguez, and G. Schmeda-Hirschmann Free radical scavengers and antioxidants from lemon grass (Cymbopogon citratus (DC.) Stapf.) Journal of Agriculture and Food Chemistry 53 7 2005 2511 2517 (Pubitemid 40471732)
12. S.W. Choi, I.F. Benzie, S.W. Ma, J.J. Strain, and B.M. Hannigan Acute hyperglycemia and oxidative stress: Direct cause and effect? Free Radical Biology and Medicine 44 7 2008 1217 1231
13. L. Cominacini, A. Rigoni, A.F. Pasini, U. Garbin, A. Davoli, M. Campagnola, A.M. Pastorino, V. Lo Cascio, and T. Sawamura The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide Journal of Biological Chemistry 276 17 2001 13750 13755
14. R.C.R.C. Devi, S.M. Sim, and R. Ismail Spasmolytic effect of citral and extracts of Cymbopogon citratus on isolated rabbit ileum Journal of Smooth Muscle Research 47 5 2011 143 156
15. R.C. Devi, S.M. Sim, and R. Ismail Effect of Cymbopogon citratus and citral on vascular smooth muscle of the isolated thoracic rat aorta Evidence-Based Complementary and Alternative Medicine 2012 2012 539475
16. A. Figueirinha, M.T. Cruz, V. Francisco, M.C. Lopes, and M.T. Batista Anti-inflammatory activity of Cymbopogon citratus leaf infusion in lipopolysaccharide-stimulated dendritic cells: Contribution of the polyphenols Journal of Medicinal Food 13 3 2010 681 690
17. J. Galle, A. Heinloth, C. Wanner, and K. Heermeier Dual effect of oxidized LDL on cell cycle in human endothelial cells through oxidative stress Kidney International. Supplement 78 2001 S120 S123
18. C. Gonzalez, M.A. Cruz, W.H. Sepulveda, and M.I. Rudolph Effects of serotonin on vascular tone of isolated human placental chorionic veins Gynecologic and Obstetric Investigation 29 2 1990 88 91 (Pubitemid 20113471)
19. B. Halliwell Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies? Archives of Biochemistry and Biophysics 476 2 2008 107 112
20. M.G. Hertog, E.J. Feskens, P.C. Hollman, M.B. Katan, and D. Kromhout Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study Lancet 342 8878 1993 1007 1011 (Pubitemid 23314801)
21. A.C. Kaliora, G.V. Dedoussis, and H. Schmidt Dietary antioxidants in preventing atherogenesis Atherosclerosis 187 1 2006 1 17 (Pubitemid 43817017)
22. M. Kamiyama, Y. Kishimoto, M. Tani, K. Utsunomiya, and K. Kondo Effects of equol on oxidized low-density lipoprotein-induced apoptosis in endothelial cells Journal of Atherosclerosis and Thrombosis 16 3 2009 239 249
23. G.C. Kite, E.A. Porter, F.C. Denison, R.J. Grayer, N.C. Veitch, I. Butler, and M.S. Simmonds Data-directed scan sequence for the general assignment of C-glycosylflavone O-glycosides in plant extracts by liquid chromatography-ion trap mass spectrometry Journal of Chromatography A 1104 1-2 2006 123 131 (Pubitemid 43099883)
24. H. Kojima, N. Nakatsubo, K. Kikuchi, Y. Urano, T. Higuchi, J. Tanaka, Y. Kudo, and T. Nagano Direct evidence of NO production in rat hippocampus and cortex using a new fluorescent indicator: DAF-2 DA NeuroReport 9 15 1998 3345 3348 (Pubitemid 28566108)
25. M.T. Koller, M.J. Leening, M. Wolbers, E.W. Steyerberg, M.G. Hunink, R. Schoop, A. Hofman, H.C. Bucher, B.M. Psaty, D.M. Lloyd-Jones, and J.C. Witteman Development and validation of a coronary risk prediction model for older U.S. and European persons in the cardiovascular health study and the Rotterdam Study Annals of Internal Medicine 157 6 2012 389 397
26. J.D. Lambert, S. Sang, and C.S. Yang Biotransformation of green tea polyphenols and the biological activities of those metabolites Molecular Pharmaceutics 4 6 2007 819 825
27. C.J. Lavie, R.V. Milani, and H.O. Ventura Obesity and cardiovascular disease: Risk factor, paradox, and impact of weight loss Journal of the American College of Cardiology 53 21 2009 1925 1932
28. H. Li, and U. Forstermann Nitric oxide in the pathogenesis of vascular disease Journal of Pathology 190 3 2000 244 254 (Pubitemid 30141371)
29. S.B. Lotito, and B. Frei Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: Cause, consequence, or epiphenomenon? Free Radical Biology and Medicine 41 12 2006 1727 1746 (Pubitemid 44839139)
30. C. Manach, A. Scalbert, C. Morand, C. Remesy, and L. Jimenez Polyphenols: Food sources and bioavailability American Journal of Clinical Nutrition 79 5 2004 727 747 (Pubitemid 41103873)
31. B. Mayer, and B. Hemmens Biosynthesis and action of nitric oxide in mammalian cells Trends in Biochemical Sciences 22 12 1997 477 481 (Pubitemid 27515914)
32. P.J. Mink, C.G. Scrafford, L.M. Barraj, L. Harnack, C.P. Hong, J.A. Nettleton, and D.R. Jacobs Jr. Flavonoid intake and cardiovascular disease mortality: A prospective study in postmenopausal women American Journal of Clinical Nutrition 85 3 2007 895 909 (Pubitemid 46393524)
33. V.P. Montecinos, C. Aguayo, C. Flores, A.W. Wyatt, J.D. Pearson, G.E. Mann, and L. Sobrevia Regulation of adenosine transport by d-glucose in human fetal endothelial cells: Involvement of nitric oxide, protein kinase C and mitogen-activated protein kinase Journal of Physiology 529 Pt 3 2000 777 790 (Pubitemid 32051077)
34. R. Orrego, E. Leiva, and J. Cheel Inhibitory effect of three C-glycosylflavonoids from Cymbopogon citratus (lemon grass) on human low density lipoprotein oxidation Molecules 14 10 2009 3906 3913
35. P. Otero, M. Viana, E. Herrera, and B. Bonet Antioxidant and pro-oxidant effects of ascorbic acid, dehydroascorbic acid and flavonoids on LDL submitted to different degrees of oxidation Free Radical Research 27 6 1997 619 626 (Pubitemid 28051189)
36. B.S. Rao, R. Shanbhoge, B.N. Rao, S.K. Adiga, D. Upadhya, B.K. Aithal, and M.R. Kumar Preventive efficacy of hydroalcoholic extract of Cymbopogon citratus against radiation-induced DNA damage on V79 cells and free radical scavenging ability against radicals generated in vitro Human and Experimental Toxicology 28 4 2009 195 202
37. S. Sang, M.J. Lee, Z. Hou, C.T. Ho, and C.S. Yang Stability of tea polyphenol (-)-epigallocatechin-3-gallate and formation of dimers and epimers under common experimental conditions Journal of Agriculture and Food Chemistry 53 24 2005 9478 9484 (Pubitemid 41784153)
38. A. Searle, L. Gomez-Rosso, T. Merono, C. Salomon, D. Duran-Sandoval, G. Giunta, C. Grant, C. Calvo, L. Lamperti, F. Brites, and C. Aguayo High LDL levels are associated with increased lipoprotein-associated phospholipase A(2) activity on nitric oxide synthesis and reactive oxygen species formation in human endothelial cells Clinical Biochemistry 44 2-3 2011 171 177
39. E. Sezik, M. Aslan, E. Yesilada, and S. Ito Hypoglycaemic activity of Gentiana olivieri and isolation of the active constituent through bioassay-directed fractionation techniques Life Sciences 76 11 2005 1223 1238 (Pubitemid 40092137)
40. J.M. Sforcin, J.T. Amaral, A. Fernandes Jr.; J.P. Sousa, and J.K. Bastos Lemon grass effects on IL-1beta and IL-6 production by macrophages Natural Product Research 23 12 2009 1151 1159
41. K.S. Suh, S. Chon, S. Oh, S.W. Kim, J.W. Kim, Y.S. Kim, and J.T. Woo Pro-oxidative effects of green tea polyphenol (-)-epigallocatechin-3-gallate on the HIT-T15 pancreatic beta cell line Cell Biology and Toxicology 26 3 2010 189 199
42. H. Takaishi, T. Taniguchi, A. Takahashi, Y. Ishikawa, and M. Yokoyama High glucose accelerates MCP-1 production via p38 MAPK in vascular endothelial cells Biochemical and Biophysical Research Communications 305 1 2003 122 128 (Pubitemid 36535416)
43. M. Tiwari, U.N. Dwivedi, and P. Kakkar Suppression of oxidative stress and pro-inflammatory mediators by Cymbopogon citratus D.C. Stapf extract in lipopolysaccharide stimulated murine alveolar macrophages Food and Chemical Toxicology 48 10 2010 2913 2919
44. R. Vasquez, M. Farias, J.L. Vega, R.S. Martin, A. Vecchiola, P. Casanello, and L. Sobrevia d-glucose stimulation of l-arginine transport and nitric oxide synthesis results from activation of mitogen-activated protein kinases p42/44 and Smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium Journal of Cellular Physiology 212 3 2007 626 632 (Pubitemid 47267532)
45. S. Yla-Herttuala Oxidized LDL and atherogenesis Annals of the New York Academy of Sciences 874 1999 134 137 (Pubitemid 29351937)
46. J.W. Zmijewski, D.R. Moellering, C. Le Goffe, A. Landar, A. Ramachandran, and V.M. Darley-Usmar Oxidized LDL induces mitochondrially associated reactive oxygen/nitrogen species formation in endothelial cells American Journal of Physiology. Heart and Circulatory Physiology 289 2 2005 H852 H861