SUMO-1 gene transfer improves cardiac function in a large-animal model of heart failure

Science Translational Medicine

Volumn 5, Issue 211, 2013, Pages

  Tilemann, Lisa ^a,b   Lee, Ahyoung ^a   Ishikawa, Kiyotake ^a   Aguero, Jaume ^a   Rapti, Kleopatra ^a   Santos Gallego, Carlos ^a   Kohlbrenner, Erik ^a   Fish, Kenneth M ^a   Kho, Changwon ^a   Hajjar, Roger J ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PARVOVIRUS VECTOR; PROTEIN SERCA2A; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CHLORIDE; SUMO 1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BALLOON OCCLUSION; CONTROLLED STUDY; CORONARY REPERFUSION; DISEASE MODEL; DRUG DOSE COMPARISON; DRUG INFUSION; DRUG MEGADOSE; GENE; GENE TRANSFER; HEART DILATATION; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE DP-DT; ISCHEMIC HEART DISEASE; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LOW DRUG DOSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SERCA2A GENE; SUMO 1 GENE; SWINE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; GENE TRANSFER TECHNIQUES; HEART; HEART FAILURE; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SUMO-1 PROTEIN; SWINE;

EID: 84890096337     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3006487     Document Type: Article

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