Effects of histone deacetylase inhibition on 24-Hour survival and end-Organ injury in a porcine trauma model: A prospective, randomized trial

Journal of Trauma and Acute Care Surgery

Volumn 75, Issue 6, 2013, Pages 1031-1039

  Nelson, Daniel W ^a   Porta, Christopher R ^a   McVay, Derek P ^a   Salgar, Shashikumar K ^b   Martin, Matthew J ^a  

^a Tulane Department of Surgery   (United States)

^b MADIGAN ARMY MEDICAL CENTER   (United States)

Author keywords

Hemorrhage; Histone deacetylase inhibition; Ischemia reperfusion; Swine; Trauma

Indexed keywords

ADRENALIN; CREATININE; HISTONE DEACETYLASE; LIDOCAINE; PLACEBO; UREA; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CLAMPING; BLEEDING; CONFERENCE PAPER; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CRYSTALLOID; DRUG EFFECT; DRUG EFFICACY; ENZYME INHIBITION; FLUID RESUSCITATION; HEART OUTPUT; HEMODYNAMICS; HEMORRHAGIC SHOCK; HISTOLOGY; LUNG WEDGE PRESSURE; MORTALITY; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RENAL PROTECTION; REPERFUSION INJURY; SINGLE BLIND PROCEDURE; SINGLE DRUG DOSE; SURVIVAL; SWINE; SYSTEMIC VASCULAR RESISTANCE; UREA NITROGEN BLOOD LEVEL;

ANIMALS; DISEASE MODELS, ANIMAL; FOLLOW-UP STUDIES; HEMODYNAMICS; HISTONE DEACETYLASE INHIBITORS; PROSPECTIVE STUDIES; RESUSCITATION; SHOCK, HEMORRHAGIC; SWINE; TREATMENT OUTCOME; WOUNDS AND INJURIES;

EID: 84890095231     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e31829d01bf     Document Type: Conference Paper

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