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Volumn 123, Issue 19, 2010, Pages 2682-2687

Valproic acid attenuates the multiple-organ dysfunction in a rat model of septic shock

Author keywords

Acetylation; Inflammation; Septic shock; Valproic acid

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATININE; HISTONE H3; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; NITROGEN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; VALPROIC ACID;

EID: 78149273915     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2010.19.012     Document Type: Article
Times cited : (37)

References (28)
  • 1
    • 59649117667 scopus 로고    scopus 로고
    • Molecular biology of inflammation and sepsis: A primer
    • Cinel I, Opal SM. Molecular biology of inflammation and sepsis: a primer. Crit Care Med 2009; 37: 291-304.
    • (2009) Crit Care Med , vol.37 , pp. 291-304
    • Cinel, I.1    Opal, S.M.2
  • 2
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
    • Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 2001; 276: 36734-36741.
    • (2001) J Biol Chem , vol.276 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5    Klein, P.S.6
  • 3
    • 34248530339 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: Multiple mechanisms of action
    • Kim HJ, Rowe M, Ren M, Hong JS, Chen PS, Chuang DM. Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther 2007; 321: 892-901.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 892-901
    • Kim, H.J.1    Rowe, M.2    Ren, M.3    Hong, J.S.4    Chen, P.S.5    Chuang, D.M.6
  • 4
    • 33645775726 scopus 로고    scopus 로고
    • Histone hyperacetylation is associated with amelioration of experimental colitis in mice
    • Glauben R, Batra A, Fedke I, Zeitz M, Lehr HA, Leoni F, et al. Histone hyperacetylation is associated with amelioration of experimental colitis in mice. J Immunol 2006; 176: 5015-5022.
    • (2006) J Immunol , vol.176 , pp. 5015-5022
    • Glauben, R.1    Batra, A.2    Fedke, I.3    Zeitz, M.4    Lehr, H.A.5    Leoni, F.6
  • 5
    • 34249818489 scopus 로고    scopus 로고
    • Histone deacetylase as therapeutic target in a rodent model of hemorrhagic shock: Effect of different resuscitation strategies on lung and liver
    • Lin T, Chen H, Koustova E, Sailhamer EA, Li Y, Shults C, et al. Histone deacetylase as therapeutic target in a rodent model of hemorrhagic shock: effect of different resuscitation strategies on lung and liver. Surgery 2007; 141: 784-794.
    • (2007) Surgery , vol.141 , pp. 784-794
    • Lin, T.1    Chen, H.2    Koustova, E.3    Sailhamer, E.A.4    Li, Y.5    Shults, C.6
  • 6
    • 47749117924 scopus 로고    scopus 로고
    • Cell protective mechanism of valproic acid in lethal hemorrhagic shock
    • Li Y, Liu B, Sailhamer EA, Yuan Z, Shults C, Velmahos GC, et al. Cell protective mechanism of valproic acid in lethal hemorrhagic shock. Surgery 2008; 144: 217-224.
    • (2008) Surgery , vol.144 , pp. 217-224
    • Li, Y.1    Liu, B.2    Sailhamer, E.A.3    Yuan, Z.4    Shults, C.5    Velmahos, G.C.6
  • 7
    • 68249144223 scopus 로고    scopus 로고
    • Melatonin reduces acute lung injury in endotoxemic rats
    • Shang Y, XU SP, Wu Y, Jiang YX, Wu ZY, Yuan SY, et al. Melatonin reduces acute lung injury in endotoxemic rats. Chin Med J 2009; 122: 1388-1393.
    • (2009) Chin Med J , vol.122 , pp. 1388-1393
    • Shang, Y.1    Xu, S.P.2    Wu, Y.3    Jiang, Y.X.4    Wu, Z.Y.5    Yuan, S.Y.6
  • 8
    • 68249133582 scopus 로고    scopus 로고
    • Reduction of pulmonary inflammatory response by erythropoietin in a rat model of endotoxaemia
    • Shang Y, Jiang YX, Xu SP, Wu Y, Wu ZY, Yuan SY, et al. Reduction of pulmonary inflammatory response by erythropoietin in a rat model of endotoxaemia. Chin Med J 2009; 122: 834-838.
    • (2009) Chin Med J , vol.122 , pp. 834-838
    • Shang, Y.1    Jiang, Y.X.2    Xu, S.P.3    Wu, Y.4    Wu, Z.Y.5    Yuan, S.Y.6
  • 9
    • 3042651448 scopus 로고    scopus 로고
    • Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: Potential roles of histone deacetylase inhibition and heat shock protein induction
    • Ren M, Leng Y, Jeong M, Leeds PR, Chuang DM. Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction. J Neurochem 2004; 89: 1358-1367.
    • (2004) J Neurochem , vol.89 , pp. 1358-1367
    • Ren, M.1    Leng, Y.2    Jeong, M.3    Leeds, P.R.4    Chuang, D.M.5
  • 10
    • 34147199586 scopus 로고    scopus 로고
    • Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation
    • Sinn DI, Kim SJ, Chu K, Jung KH, Lee ST, Song EC, et al. Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation. Neurobiol Dis 2007; 26: 464-472.
    • (2007) Neurobiol Dis , vol.26 , pp. 464-472
    • Sinn, D.I.1    Kim, S.J.2    Chu, K.3    Jung, K.H.4    Lee, S.T.5    Song, E.C.6
  • 11
    • 67650305179 scopus 로고    scopus 로고
    • Hepatoprotection and lethality rescue by histone deacetylase inhibitor valproic acid in fatal hemorrhagic shock
    • Gonzales ER, Chen H, Munuve RM, Mehrani T, Nadel A, Koustova E. Hepatoprotection and lethality rescue by histone deacetylase inhibitor valproic acid in fatal hemorrhagic shock. J Trauma 2008; 65: 554-565.
    • (2008) J Trauma , vol.65 , pp. 554-565
    • Gonzales, E.R.1    Chen, H.2    Munuve, R.M.3    Mehrani, T.4    Nadel, A.5    Koustova, E.6
  • 12
    • 33646821053 scopus 로고    scopus 로고
    • Valproic acid prevents hemorrhage-associated lethality and affects the acetylation pattern of cardiac histones
    • Gonzales E, Chen H, Munuve R, Mehrani T, Britten-Webb J, Nadel A, et al. Valproic acid prevents hemorrhage-associated lethality and affects the acetylation pattern of cardiac histones. Shock 2006; 25: 395-401.
    • (2006) Shock , vol.25 , pp. 395-401
    • Gonzales, E.1    Chen, H.2    Munuve, R.3    Mehrani, T.4    Britten-Webb, J.5    Nadel, A.6
  • 13
    • 67650651895 scopus 로고    scopus 로고
    • Surviving blood loss without blood transfusion in a swine poly-trauma model
    • Alam HB, Shuja F, Butt MU, Duggan M, Li Y, Zacharias N, et al. Surviving blood loss without blood transfusion in a swine poly-trauma model. Surgery 2009; 146: 325-333.
    • (2009) Surgery , vol.146 , pp. 325-333
    • Alam, H.B.1    Shuja, F.2    Butt, M.U.3    Duggan, M.4    Li, Y.5    Zacharias, N.6
  • 15
    • 67349186689 scopus 로고    scopus 로고
    • Erythropoietin attenuates lung injury in lipopolysaccharide treated rats
    • Shang Y, Li X, Prasad P, Xu S, Yao S, Liu D, et al. Erythropoietin attenuates lung injury in lipopolysaccharide treated rats. J Surg Res 2009; 155: 104-110.
    • (2009) J Surg Res , vol.155 , pp. 104-110
    • Shang, Y.1    Li, X.2    Prasad, P.3    Xu, S.4    Yao, S.5    Liu, D.6
  • 16
    • 58149109249 scopus 로고    scopus 로고
    • Valproic acid attenuates inflammation in experimental autoimmune neuritis
    • Zhang Z, Zhang ZY, Fauser U, Schluesener HJ. Valproic acid attenuates inflammation in experimental autoimmune neuritis. Cell Mol Life Sci 2008; 65: 4055-4065.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 4055-4065
    • Zhang, Z.1    Zhang, Z.Y.2    Fauser, U.3    Schluesener, H.J.4
  • 17
    • 15544387446 scopus 로고    scopus 로고
    • Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: Role of microglia
    • Peng GS, Li G, Tzeng NS, Chen PS, Chuang DM, Hsu YD, et al. Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia. Brain Res Mol Brain Res 2005; 134: 162-169.
    • (2005) Brain Res Mol Brain Res , vol.134 , pp. 162-169
    • Peng, G.S.1    Li, G.2    Tzeng, N.S.3    Chen, P.S.4    Chuang, D.M.5    Hsu, Y.D.6
  • 19
    • 33644946604 scopus 로고    scopus 로고
    • HATs and HDACs in neurodegeneration: A tale of disconcerted acetylation homeostasis
    • Saha RN, Pahan K. HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis. Cell Death Differ 2006; 13: 539-550.
    • (2006) Cell Death Differ , vol.13 , pp. 539-550
    • Saha, R.N.1    Pahan, K.2
  • 21
    • 34047218122 scopus 로고    scopus 로고
    • HDAC inhibitors as anti-inflammatory agents
    • Adcock IM. HDAC inhibitors as anti-inflammatory agents. Br J Pharmacol 2007; 150: 829-831.
    • (2007) Br J Pharmacol , vol.150 , pp. 829-831
    • Adcock, I.M.1
  • 22
    • 0037022598 scopus 로고    scopus 로고
    • The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines
    • Leoni F, Zaliani A, Bertolini G, Porro G, Pagani P, Pozzi P, et al. The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. Proc Natl Acad Sci USA 2002; 99: 2995-3000.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2995-3000
    • Leoni, F.1    Zaliani, A.2    Bertolini, G.3    Porro, G.4    Pagani, P.5    Pozzi, P.6
  • 23
    • 57349114027 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model
    • Choi Y, Park SK, Kim HM, Kang JS, Yoon YD, Han SB, et al. Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model. Exp Mol Med 2008; 40: 574-581.
    • (2008) Exp Mol Med , vol.40 , pp. 574-581
    • Choi, Y.1    Park, S.K.2    Kim, H.M.3    Kang, J.S.4    Yoon, Y.D.5    Han, S.B.6
  • 24
    • 35948983828 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment
    • Bode KA, Schroder K, Hume DA, Ravasi T, Heeg K, Sweet MJ, et al. Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology 2007; 122: 596-606.
    • (2007) Immunology , vol.122 , pp. 596-606
    • Bode, K.A.1    Schroder, K.2    Hume, D.A.3    Ravasi, T.4    Heeg, K.5    Sweet, M.J.6
  • 25
    • 34047255367 scopus 로고    scopus 로고
    • Valproic acid, a molecular lead to multiple regulatory pathways
    • (Praha)
    • Kostrouchová M, Kostrouch Z, Kostrouchová M. Valproic acid, a molecular lead to multiple regulatory pathways. Folia Biol (Praha) 2007; 53: 37-49.
    • (2007) Folia Biol , vol.53 , pp. 37-49
    • Kostrouchová, M.1    Kostrouch, Z.2    Kostrouchová, M.3
  • 26
    • 24944567775 scopus 로고    scopus 로고
    • GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat
    • Dugo L, Collin M, Allen DA, Patel NS, Bauer I, Mervaala EM, et al. GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat. Crit Care Med 2005; 33: 1903-1912.
    • (2005) Crit Care Med , vol.33 , pp. 1903-1912
    • Dugo, L.1    Collin, M.2    Allen, D.A.3    Patel, N.S.4    Bauer, I.5    Mervaala, E.M.6
  • 27
    • 77955926548 scopus 로고    scopus 로고
    • Treatment with histone deacetylase inhibitor attenuates MAP kinase mediated liver injury in a lethal model of septic shock
    • Finkelstein RA, Li Y, Liu B, Shuja F, Fukudome E, Velmahos GC, et al. Treatment with histone deacetylase inhibitor attenuates MAP kinase mediated liver injury in a lethal model of septic shock. J Surg Res 2010; 163: 146-154.
    • (2010) J Surg Res , vol.163 , pp. 146-154
    • Finkelstein, R.A.1    Li, Y.2    Liu, B.3    Shuja, F.4    Fukudome, E.5    Velmahos, G.C.6
  • 28
    • 77955287968 scopus 로고    scopus 로고
    • Surviving lethal septic shock without fluid resuscitation in a rodent model
    • Li Y, Liu B, Fukudome EY, Kochanek AR, Finkelstein RA, Chong W, et al. Surviving lethal septic shock without fluid resuscitation in a rodent model. Surgery 2010; 148: 246-254.
    • (2010) Surgery , vol.148 , pp. 246-254
    • Li, Y.1    Liu, B.2    Fukudome, E.Y.3    Kochanek, A.R.4    Finkelstein, R.A.5    Chong, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.