-
1
-
-
0038023197
-
Inhibition of hepatitis B virus in mice by RNA interference
-
McCaffrey AP, Nakai H, Pandey K, Huang Z, Salazar FH, Xu H, et al. Inhibition of hepatitis B virus in mice by RNA interference. Nat Biotechnol 2003;21:639-44.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 639-644
-
-
McCaffrey, A.P.1
Nakai, H.2
Pandey, K.3
Huang, Z.4
Salazar, F.H.5
Xu, H.6
-
3
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin XF, An DS, Chen ISY, Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Natl Acad Sci USA 2003;100:183-8.
-
(2003)
Natl Acad Sci USA
, vol.100
, pp. 183-188
-
-
Qin, X.F.1
An, D.S.2
Chen, I.S.Y.3
Baltimore, D.4
-
4
-
-
77957820261
-
RNAi and small interfering RNAs in human disease therapeutic applications
-
Lares MR, Rossi JJ, Ouellet DL. RNAi and small interfering RNAs in human disease therapeutic applications. Trends Biotechnol 2010;28:570-9.
-
(2010)
Trends Biotechnol
, vol.28
, pp. 570-579
-
-
Lares, M.R.1
Rossi, J.J.2
Ouellet, D.L.3
-
5
-
-
59849103061
-
Drug delivery of siRNA therapeutics: Potentials and limits of nanosystems
-
Reischl D, Zimmer A. Drug delivery of siRNA therapeutics: potentials and limits of nanosystems. Nano Med NanoTechnol 2009;5:8-20.
-
(2009)
Nano Med NanoTechnol
, vol.5
, pp. 8-20
-
-
Reischl, D.1
Zimmer, A.2
-
6
-
-
80054718538
-
Self-assembled and nanostructured siRNA delivery systems
-
Jeong JH, Park TG, Kim SH. Self-assembled and nanostructured siRNA delivery systems. Pharm Res 2011;28:2072-85.
-
(2011)
Pharm Res
, vol.28
, pp. 2072-2085
-
-
Jeong, J.H.1
Park, T.G.2
Kim, S.H.3
-
7
-
-
38049165716
-
Sheddable coatings for long-circulating nanoparticles
-
Romberg B, Hennink WE, Storm G. Sheddable coatings for long-circulating nanoparticles. Pharm Res 2008;25:55-71.
-
(2008)
Pharm Res
, vol.25
, pp. 55-71
-
-
Romberg, B.1
Hennink, W.E.2
Storm, G.3
-
8
-
-
84864508341
-
Stimuli-responsive polymers and nanomaterials for gene delivery and imaging applications
-
Shim MS, Kwon YJ. Stimuli-responsive polymers and nanomaterials for gene delivery and imaging applications. Adv Drug Deliv Rev 2012;65:1046-59.
-
(2012)
Adv Drug Deliv Rev
, vol.65
, pp. 1046-1059
-
-
Shim, M.S.1
Kwon, Y.J.2
-
9
-
-
84856155804
-
Sheddable ternary nanoparticles for tumor acidity-targeted siRNA delivery
-
Yang X-Z, Du J-Z, Dou S, Mao C-Q, Long H-Y, Wang J. Sheddable ternary nanoparticles for tumor acidity-targeted siRNA delivery. ACS Nano 2012;6:771-81.
-
(2012)
ACS Nano
, vol.6
, pp. 771-781
-
-
Yang, X.-Z.1
Du, J.-Z.2
Dou, S.3
Mao, C.-Q.4
Long, H.-Y.5
Wang, J.6
-
10
-
-
80053128144
-
Non-viral gene transfection in vitro using endosomal pH-sensitive reversibly hydrophobilized polyethylenimine
-
Liu Z, Zheng M, Meng F, Zhong Z. Non-viral gene transfection in vitro using endosomal pH-sensitive reversibly hydrophobilized polyethylenimine. Biomaterials 2011;32:9109-19.
-
(2011)
Biomaterials
, vol.32
, pp. 9109-9119
-
-
Liu, Z.1
Zheng, M.2
Meng, F.3
Zhong, Z.4
-
11
-
-
36649038352
-
Thermally sensitive cationic polymer nanocapsules for specific cytosolic delivery and efficient gene silencing of siRNA: Swelling induced physical disruption of endosome by cold shock
-
Lee SH, Choi SH, Kim SH, Park TG. Thermally sensitive cationic polymer nanocapsules for specific cytosolic delivery and efficient gene silencing of siRNA: swelling induced physical disruption of endosome by cold shock. J Control Release 2008;125:25-32.
-
(2008)
J Control Release
, vol.125
, pp. 25-32
-
-
Lee, S.H.1
Choi, S.H.2
Kim, S.H.3
Park, T.G.4
-
12
-
-
77952236567
-
Characterization of gene expression regulation using D-RECS polymer by enzymatic reaction for an effective design of enzyme-responsive gene regulator
-
Sato YT, Kawamura K, Niidome T, Katayama Y. Characterization of gene expression regulation using D-RECS polymer by enzymatic reaction for an effective design of enzyme-responsive gene regulator. J Control Release 2010;143:344-9.
-
(2010)
J Control Release
, vol.143
, pp. 344-349
-
-
Sato, Y.T.1
Kawamura, K.2
Niidome, T.3
Katayama, Y.4
-
13
-
-
79951917191
-
Redox-active polymer microcapsules for the delivery of a survivin-specific siRNA in prostate cancer cells
-
Becker AL, Orlotti NI, Folini M, Cavalieri F, Zelikin AN, Johnston APR, et al. Redox-active polymer microcapsules for the delivery of a survivin-specific siRNA in prostate cancer cells. ACS Nano 2011;5:1335-44.
-
(2011)
ACS Nano
, vol.5
, pp. 1335-1344
-
-
Becker, A.L.1
Orlotti, N.I.2
Folini, M.3
Cavalieri, F.4
Zelikin, A.N.5
Johnston, A.P.R.6
-
14
-
-
33846452896
-
Novel bioreducible poly(amido amine)s for highly efficient gene delivery
-
Lin C, Zhong Z, Lok MC, Jiang X, Hennink WE, Feijen J, et al. Novel bioreducible poly(amido amine)s for highly efficient gene delivery. Bioconjug Chem 2006;18:138-45.
-
(2006)
Bioconjug Chem
, vol.18
, pp. 138-145
-
-
Lin, C.1
Zhong, Z.2
Lok, M.C.3
Jiang, X.4
Hennink, W.E.5
Feijen, J.6
-
15
-
-
58549112795
-
Environment-responsive block copolymer micelles with a disulfide crosslinked core for enhanced siRNA delivery
-
Matsumoto S, Christie RJ, Nishiyama N, Miyata K, Ishii A, Oba M, et al. Environment-responsive block copolymer micelles with a disulfide crosslinked core for enhanced siRNA delivery. Biomacromolecules 2008;10: 119-27.
-
(2008)
Biomacromolecules
, vol.10
, pp. 119-127
-
-
Matsumoto, S.1
Christie, R.J.2
Nishiyama, N.3
Miyata, K.4
Ishii, A.5
Oba, M.6
-
16
-
-
84863229405
-
Reversibly shielded DNA polyplexes based on bioreducible PDMAEMA-SS-PEG-SSPDMAEMA triblock copolymers mediate markedly enhanced nonviral gene transfection
-
Zhu C, Zheng M, Meng F, Mickler FM, Ruthardt N, Zhu X, et al. Reversibly shielded DNA polyplexes based on bioreducible PDMAEMA-SS-PEG-SSPDMAEMA triblock copolymers mediate markedly enhanced nonviral gene transfection. Biomacromolecules 2012;13:769-78.
-
(2012)
Biomacromolecules
, vol.13
, pp. 769-778
-
-
Zhu, C.1
Zheng, M.2
Meng, F.3
Mickler, F.M.4
Ruthardt, N.5
Zhu, X.6
-
17
-
-
33845216721
-
PEG conjugated VEGF siRNA for anti-angiogenic gene therapy
-
Kim SH, Jeong JH, Lee SH, Kim SW, Park TG. PEG conjugated VEGF siRNA for anti-angiogenic gene therapy. J Control Release 2006;116:123-9.
-
(2006)
J Control Release
, vol.116
, pp. 123-129
-
-
Kim, S.H.1
Jeong, J.H.2
Lee, S.H.3
Kim, S.W.4
Park, T.G.5
-
18
-
-
42949103542
-
PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors
-
Takae S, Miyata K, Oba M, Ishii T, Nishiyama N, Itaka K, et al. PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors. J Am Chem Soc 2008;130:6001-9.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 6001-6009
-
-
Takae, S.1
Miyata, K.2
Oba, M.3
Ishii, T.4
Nishiyama, N.5
Itaka, K.6
-
19
-
-
0347926091
-
Drug delivery strategy utilizing conjugation via reversible disulfide linkages: Role and site of cellular reducing activities
-
Saito G, Swanson JA, Lee K-D. Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities. Adv Drug Deliv Rev 2003;55:199-215.
-
(2003)
Adv Drug Deliv Rev
, vol.55
, pp. 199-215
-
-
Saito, G.1
Swanson, J.A.2
Lee, K.-D.3
-
20
-
-
0025098737
-
A cysteine-specific lysosomal transport system provides a major route for the delivery of thiol to human fibroblast lysosomes: Possible role in supporting lysosomal proteolysis
-
Pisoni RL, Acker TL, Lisowski KM, Lemons RM, Thoene JG. A cysteine-specific lysosomal transport system provides a major route for the delivery of thiol to human fibroblast lysosomes: possible role in supporting lysosomal proteolysis. J Cell Biol 1990;110:327-35.
-
(1990)
J Cell Biol
, vol.110
, pp. 327-335
-
-
Pisoni, R.L.1
Acker, T.L.2
Lisowski, K.M.3
Lemons, R.M.4
Thoene, J.G.5
-
21
-
-
0842346326
-
Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells
-
Muratovska A, Eccles MR. Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells. FEBS Lett 2004;558:63-8.
-
(2004)
FEBS Lett
, vol.558
, pp. 63-68
-
-
Muratovska, A.1
Eccles, M.R.2
-
22
-
-
80052962159
-
Structural contributions of blocked or grafted poly(2-dimethylaminoethyl methacrylate) on PEGylated polycaprolactone nanoparticles in siRNA delivery
-
Lin D, Huang Y, Jiang Q, Zhang W, Yue X, Guo S, et al. Structural contributions of blocked or grafted poly(2-dimethylaminoethyl methacrylate) on PEGylated polycaprolactone nanoparticles in siRNA delivery. Biomaterials 2011;32: 8730-42.
-
(2011)
Biomaterials
, vol.32
, pp. 8730-8742
-
-
Lin, D.1
Huang, Y.2
Jiang, Q.3
Zhang, W.4
Yue, X.5
Guo, S.6
-
23
-
-
78549274320
-
Amphiphilic and biodegradable methoxy polyethylene glycol-block- (polycaprolactone-graftpoly( 2-(dimethylamino)ethyl methacrylate)) as an effective gene carrier
-
Guo ST, Huang YY, Wei T, Zhang WD, Wang WW, Lin D, et al. Amphiphilic and biodegradable methoxy polyethylene glycol-block-(polycaprolactone-graftpoly( 2-(dimethylamino)ethyl methacrylate)) as an effective gene carrier. Biomaterials 2011;32:879-89.
-
(2011)
Biomaterials
, vol.32
, pp. 879-889
-
-
Guo, S.T.1
Huang, Y.Y.2
Wei, T.3
Zhang, W.D.4
Wang, W.W.5
Lin, D.6
-
24
-
-
77956508753
-
Amphiphilic methoxy poly(ethylene glycol)-b-poly(epsilon-caprolactone)-b- poly(2-dimethylaminoethyl methacrylate) cationic copolymer nanoparticles as a vector for gene and drug delivery
-
Yue X, Qiao Y, Qiao N, Guo S, Xing J, Deng L, et al. Amphiphilic methoxy poly(ethylene glycol)-b-poly(epsilon-caprolactone)-b-poly(2-dimethylaminoethyl methacrylate) cationic copolymer nanoparticles as a vector for gene and drug delivery. Biomacromolecules 2010;11:2306-12.
-
(2010)
Biomacromolecules
, vol.11
, pp. 2306-2312
-
-
Yue, X.1
Qiao, Y.2
Qiao, N.3
Guo, S.4
Xing, J.5
Deng, L.6
-
25
-
-
80051512877
-
Influence of nano-carrier architecture on in vitro siRNA delivery performance and in vivo biodistribution: Polyplexes vs micelleplexes
-
Gary DJ, Lee H, Sharma R, Lee JS, Kim Y, Cui ZY, et al. Influence of nano-carrier architecture on in vitro siRNA delivery performance and in vivo biodistribution: polyplexes vs micelleplexes. ACS Nano 2011;5:3493-505.
-
(2011)
ACS Nano
, vol.5
, pp. 3493-3505
-
-
Gary, D.J.1
Lee, H.2
Sharma, R.3
Lee, J.S.4
Kim, Y.5
Cui, Z.Y.6
-
26
-
-
0036077937
-
Polyethylenimine-graft-poly(ethylene glycol) copolymers: Influence of copolymer block structure on DNA complexation and biological activities as gene delivery system
-
Petersen H, Fechner PM, Martin AL, Kunath K, Stolnik S, Roberts CJ, et al. Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. Bioconjug Chem 2002;13:845-54.
-
(2002)
Bioconjug Chem
, vol.13
, pp. 845-854
-
-
Petersen, H.1
Fechner, P.M.2
Martin, A.L.3
Kunath, K.4
Stolnik, S.5
Roberts, C.J.6
-
27
-
-
33847095924
-
Effect of PEG conformation and particle size on the cellular uptake efficiency of nanoparticles with the HepG2 cells
-
Hu Y, Xie JW, Tong YW, Wang CH. Effect of PEG conformation and particle size on the cellular uptake efficiency of nanoparticles with the HepG2 cells. J Control Release 2007;118:7-17.
-
(2007)
J Control Release
, vol.118
, pp. 7-17
-
-
Hu, Y.1
Xie, J.W.2
Tong, Y.W.3
Wang, C.H.4
-
28
-
-
84865066015
-
An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo
-
Yu T, Liu X, Bolcato-Bellemin A-L, Wang Y, Liu C, Erbacher P, et al. An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo. Angew Chem Int Ed 2012;51:8478-84.
-
(2012)
Angew Chem Int Ed
, vol.51
, pp. 8478-8484
-
-
Yu, T.1
Liu, X.2
Bolcato-Bellemin, A.-L.3
Wang, Y.4
Liu, C.5
Erbacher, P.6
-
29
-
-
0031076147
-
Ring-opening polymerization of 1,4,8-trioxaspiro[4.6]-9-undecanone: A new route to aliphatic polyesters bearing functional pendent groups
-
Tian D, Dubois P, Grandfils C, Jérôme R. Ring-opening polymerization of 1,4,8-trioxaspiro[4.6]-9-undecanone: a new route to aliphatic polyesters bearing functional pendent groups. Macromolecules 1997;30:406-9.
-
(1997)
Macromolecules
, vol.30
, pp. 406-409
-
-
Tian, D.1
Dubois, P.2
Grandfils, C.3
Jérôme, R.4
-
30
-
-
0031557567
-
Macromolecular engineering of polylactones and polylactides
-
Tian D, Dubois P, Jérôme R. Macromolecular engineering of polylactones and polylactides. 23. Synthesis and characterization of biodegradable and biocompatible homopolymers and block copolymers based on 1,4,8-trioxa[4.6]spiro-9-undecanone. Macromolecules 1997;30:1947-54.
-
(1997)
23. Synthesis and Characterization of Biodegradable and Biocompatible Homopolymers and Block Copolymers Based on 1,4,8-trioxa[4.6]spiro-9-undecanone. Macromolecules
, vol.30
, pp. 1947-1954
-
-
Tian, D.1
Dubois, P.2
Jérôme, R.3
-
31
-
-
69849089755
-
Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin
-
Sun H, Guo B, Cheng R, Meng F, Liu H, Zhong Z. Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin. Biomaterials 2009;30:6358-66.
-
(2009)
Biomaterials
, vol.30
, pp. 6358-6366
-
-
Sun, H.1
Guo, B.2
Cheng, R.3
Meng, F.4
Liu, H.5
Zhong, Z.6
-
32
-
-
34547228805
-
Polymer-based siRNA delivery: Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery
-
Gary DJ, Puri N, Won Y-Y. Polymer-based siRNA delivery: perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery. J Control Release 2007;121:64-73.
-
(2007)
J Control Release
, vol.121
, pp. 64-73
-
-
Gary, D.J.1
Puri, N.2
Won, Y.-Y.3
-
33
-
-
34547572345
-
Polymer systems for gene delivery-past, present, and future
-
Wong SY, Pelet JM, Putnam D. Polymer systems for gene delivery-past, present, and future. Prog Polym Sci 2007;32:799-837.
-
(2007)
Prog Polym Sci
, vol.32
, pp. 799-837
-
-
Wong, S.Y.1
Pelet, J.M.2
Putnam, D.3
-
34
-
-
33746070441
-
Intravenously administered short interfering RNA accumulates in the kidney and selectively suppresses gene function in renal proximal tubules
-
van de Water FM, Boerman OC, Wouterse AC, Peters JGP, Russel FGM, Masereeuw R. Intravenously administered short interfering RNA accumulates in the kidney and selectively suppresses gene function in renal proximal tubules. Drug Metab Dispos 2006;34:1393-7.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1393-1397
-
-
Van De Water, F.M.1
Boerman, O.C.2
Wouterse, A.C.3
Peters, J.G.P.4
Russel, F.G.M.5
Masereeuw, R.6
-
35
-
-
84856956282
-
Delivery of siRNA to the mouse lung via a functionalized lipopolyamine
-
Polach KJ, Matar M, Rice J, Slobodkin G, Sparks J, Congo R, et al. Delivery of siRNA to the mouse lung via a functionalized lipopolyamine. Mol Ther 2012;20:91-100.
-
(2012)
Mol Ther
, vol.20
, pp. 91-100
-
-
Polach, K.J.1
Matar, M.2
Rice, J.3
Slobodkin, G.4
Sparks, J.5
Congo, R.6
-
36
-
-
84857795022
-
Systemic delivery of siRNA via LCP nanoparticle efficiently inhibits lung metastasis
-
Yang Y, Li J, Liu F, Huang L. Systemic delivery of siRNA via LCP nanoparticle efficiently inhibits lung metastasis. Mol Ther 2012;20:609-15.
-
(2012)
Mol Ther
, vol.20
, pp. 609-615
-
-
Yang, Y.1
Li, J.2
Liu, F.3
Huang, L.4
-
37
-
-
61849103493
-
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes
-
Malek A, Merkel O, Fink L, Czubayko F, Kissel T, Aigner A. In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes. Toxicol Appl Pharm 2009;236:97-108.
-
(2009)
Toxicol Appl Pharm
, vol.236
, pp. 97-108
-
-
Malek, A.1
Merkel, O.2
Fink, L.3
Czubayko, F.4
Kissel, T.5
Aigner, A.6
-
38
-
-
0036077674
-
Poly(ethylenimine-co-Llactamide-co-succinamide): A biodegradable polyethylenimine derivative with an advantageous pH-dependent hydrolytic degradation for gene delivery
-
Petersen H, Merdan T, Kunath K, Fischer D, Kissel T. Poly(ethylenimine- co-Llactamide-co-succinamide): a biodegradable polyethylenimine derivative with an advantageous pH-dependent hydrolytic degradation for gene delivery. Bioconjug Chem 2002;13:812-21.
-
(2002)
Bioconjug Chem
, vol.13
, pp. 812-821
-
-
Petersen, H.1
Merdan, T.2
Kunath, K.3
Fischer, D.4
Kissel, T.5
-
39
-
-
0041701404
-
Novel biodegradable ternary copolymers hy-PEI-g-PCL-b-PEG: Synthesis, characterization, and potential as efficient nonviral gene delivery vectors
-
Shuai XT, Merdan T, Unger F, Wittmar M, Kissel T. Novel biodegradable ternary copolymers hy-PEI-g-PCL-b-PEG: synthesis, characterization, and potential as efficient nonviral gene delivery vectors. Macromolecules 2003;36:5751-9.
-
(2003)
Macromolecules
, vol.36
, pp. 5751-5759
-
-
Shuai, X.T.1
Merdan, T.2
Unger, F.3
Wittmar, M.4
Kissel, T.5
-
40
-
-
51049104302
-
Pharmacokinetics and biodistribution of nanoparticles
-
Li SD, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Mol Pharm 2008;5:496-504.
-
(2008)
Mol Pharm
, vol.5
, pp. 496-504
-
-
Li, S.D.1
Huang, L.2
-
41
-
-
33845388144
-
Micellar nanocarriers: Pharmaceutical perspectives
-
Torchilin VP. Micellar nanocarriers: pharmaceutical perspectives. Pharm Res 2007;24:1-16.
-
(2007)
Pharm Res
, vol.24
, pp. 1-16
-
-
Torchilin, V.P.1
-
42
-
-
79953048071
-
Tumor delivery of macromolecular drugs based on the EPR effect
-
Torchilin V. Tumor delivery of macromolecular drugs based on the EPR effect. Adv Drug Deliv Rev 2011;63:131-5.
-
(2011)
Adv Drug Deliv Rev
, vol.63
, pp. 131-135
-
-
Torchilin, V.1
-
43
-
-
84862829846
-
Tumor-targeting hyaluronic acid nanoparticles for photodynamic imaging and therapy
-
Yoon HY, Koo H, Choi KY, Lee SJ, Kim K, Kwon IC, et al. Tumor-targeting hyaluronic acid nanoparticles for photodynamic imaging and therapy. Biomaterials 2012;33:3980-9.
-
(2012)
Biomaterials
, vol.33
, pp. 3980-3989
-
-
Yoon, H.Y.1
Koo, H.2
Choi, K.Y.3
Lee, S.J.4
Kim, K.5
Kwon, I.C.6
|