Characterization of gene expression regulation using D-RECS polymer by enzymatic reaction for an effective design of enzyme-responsive gene regulator

Journal of Controlled Release

Volumn 143, Issue 3, 2010, Pages 344-349

  Sato, Yuko T ^a,b   Kawamura, Kenji ^a,b   Niidome, Takuro ^a,b   Katayama, Yoshiki ^a,b  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

D RECS; Direct observation; Functional regulation of DNA; Gene delivery; Peptide

Indexed keywords

ARTIFICIAL GENE; CASPASE-3; CELL-FREE SYSTEM; CELLULAR SIGNALS; DIRECT OBSERVATION; DNA STRANDS; ENZYMATIC REACTION; FUNCTIONAL REGULATION; GENE CARRIER; GENE DELIVERY; GENE DELIVERY SYSTEMS; GENE REGULATIONS; GENE REGULATORS; GENE TRANSCRIPTIONS; HIGH-ORDER STRUCTURE; IN-VIVO; INTRACELLULAR SIGNALING; NEUTRAL POLYMERS; POLYMER BACKBONES; POLYMER CHAINS; RESTRICTION ENZYMES; RNA POLYMERASE; SITE-SPECIFIC; SUBSTRATE PEPTIDES; TARGET CELLS; TARGETED GENE DELIVERY;

CATALYSTS; DNA; ENZYMES; GENE THERAPY; GENE TRANSFER; PEPTIDES; POLYMERS; RNA; TARGETS; TRANSCRIPTION;

GENE EXPRESSION REGULATION;

CASPASE 3; DNA; DRUG CARRIER; DRUG DELIVERY SYSTEM RESPONDING TO CELLULAR SIGNALS POLYMER; RESTRICTION ENDONUCLEASE; RNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; CELL FREE SYSTEM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA PACKAGING; DNA PROTEIN COMPLEX; DNA STRAND; ENZYME MECHANISM; ENZYME REGULATION; GENE EXPRESSION REGULATION; MOLECULAR RECOGNITION; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FOLDING; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; CASPASE 3; DNA; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; MOLECULAR SEQUENCE DATA; PEPTIDES;

EID: 77952236567     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.01.013     Document Type: Article

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