Defective control of vitamin D receptor-mediated epithelial STAT1 signalling predisposes to severe respiratory syncytial virus bronchiolitis

Journal of Pathology

Volumn 232, Issue 1, 2014, Pages 57-64

  Stoppelenburg, Arie Jan ^a   Von Hegedus, Johannes Hendrick ^a   Huis In'T Veld, Ron ^a   Bont, Louis ^b   Boes, Marianne ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

lung; respiratory syncytial virus; STAT1; vitamin D

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 7; MESSENGER RNA; STAT1 PROTEIN; VITAMIN D; VITAMIN D RECEPTOR;

ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE PREDISPOSITION; DISEASE SEVERITY; FOKI GENE; GENE OVEREXPRESSION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOPATHOLOGY; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR GENE; RESPIRATORY EPITHELIUM; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SIGNAL TRANSDUCTION; VIRAL BRONCHIOLITIS; VITAMIN D DEFICIENCY;

LUNG; RESPIRATORY SYNCYTIAL VIRUS; STAT1; VITAMIN D;

ADULT; BRONCHIOLITIS; CASE-CONTROL STUDIES; CELL LINE; DISEASE SUSCEPTIBILITY; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, VIRAL; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-1; MACROPHAGES; MALE; NF-KAPPA B; PHOSPHORYLATION; POLYMORPHISM, GENETIC; RECEPTORS, CALCITRIOL; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; RISK FACTORS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; VIRUS REPLICATION; YOUNG ADULT;

EID: 84890072669     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4267     Document Type: Article

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