Calcitriol [1, 25[OH]2 D3] pre- and post-treatment suppresses inflammatory response to influenza A (H1N1) infection in human lung A549 epithelial cells

European Journal of Nutrition

Volumn 52, Issue 4, 2013, Pages 1405-1415

  Khare, Drirh ^a   Godbole, Nachiket M ^a   Pawar, Shailesh D ^b   Mohan, Vishwa ^a   Pandey, Gaurav ^a   Gupta, Sushil ^a   Kumar, Deepak ^a   Dhole, Tapan N ^a   Godbole, Madan M ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b NATIONAL INSTITUTE OF VIROLOGY   (India)

Author keywords

Chemokines; Cytokines; Inflammatory response; Influenza A (H1N1); Vitamin D

Indexed keywords

BETA INTERFERON; CALCITRIOL; INTERFERON STIMULATED GENE 15 PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; M PROTEIN; MESSENGER RNA; NUCLEIC ACID BINDING PROTEIN; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RESPONSE; DOWN REGULATION; HUMAN; HUMAN CELL; INFLAMMATION; INFLUENZA A (H1N1); LUNG ALVEOLUS EPITHELIUM; NONHUMAN; TRANSCRIPTION REGULATION; VIRAL CLEARANCE;

APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CALCITRIOL; CELL LINE; CELL SURVIVAL; CHEMOKINES; CULTURE MEDIA, CONDITIONED; CYTOKINES; DOWN-REGULATION; HEMAGGLUTINATION TESTS; HUMANS; IMMUNOLOGIC FACTORS; INFLUENZA A VIRUS, H1N1 SUBTYPE; KINETICS; PNEUMOCYTES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VIRAL MATRIX PROTEINS;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

EID: 84878528075     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-012-0449-7     Document Type: Article

References (41)

1. Rao BL, Yeolekar LR, Kadam SS, Pawar MS, Kulkarni PB, More BA, Khude MR (2005) Influenza surveillance in Pune, India, 2003. Southeast Asian J Trop Med Public Health 36:906-909
2. Geiss GK, Salvatore M, Tumpey TM, Carter VS, Wang X, Basler CF, Taubenberger JK, Bumgarner RE, Palese P, Katze MG, Garcia-Sastre A (2002) Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc Natl Acad Sci USA 99:10736-10741
3. Chakrabarti AK, Pawar SD, Cherian SS, Koratkar SS, Jadhav SM, Pal B (2009) Characterization of the Influenza A H5N1 Viruses of the 2008-09 Outbreaks in India Reveals a Third Introduction and Possible Endemicity. PLoS ONE 4(11):e7846
4. Li Y, Zhou H, Wen Z, Wu S, Huang C, Jia G, Chen H, Jin M (2011) Transcription analysis on response of swine lung to H1N1 swine influenza virus. BMC Genom 12:398
5. Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team. Dawood FS, Jain S, Finelli L, Shaw MW, Lindstrom S, Garten RJ, Gubareva LV, Xu X, Bridges CB, Uyeki TM (2009) Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 360:2605-2615
6. Kyriakis CS, Olsen CW, Carman S, Brown IH, Brookes SM, Doorsselaere JV, Reeth KV (2010) Serologic cross-reactivity with pandemic (H1N1) 2009 virus in pigs, Europe. Emerg Infect Dis 16(1):96-99
7. Loving CL, Brockmeier SL, Vincent AL, Palmer MV, Sacco RE, Nicholson TL (2010) Influenza virus co-infection with Bordetella bronchiseptica enhances bacterial colonization and host responses exacerbating pulmonary lesions. Microb Pathog 49:237-245
8. Jo SK, Kim HS, Cho SW, Seo SH (2007) Pathogenesis and inflammatory responses of swine H1N2 influenza viruses in pigs. Virus Res 129:64-70
9. Ghosh S, May MJ, Kopp EB (1998) NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 16:225-260
10. Lee SM, Gardy JL, Cheung CY, Cheung TKW, Hui KPY, Ip NY, Guan Y, Hancock REW, Peiris JS (2009) Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages. PLoS ONE 4(12):e8072
11. Uchide N, Toyoda H (2011) Antioxidant therapy as a potential approach to severe influenza-associated complications. Molecules 16:2032-2052
12. Hansdottir S, Monick MM, Hinde SL, Lovan N, Look DC, Hunninghake GW (2008) Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol 181:7090-7099
13. Hansdottir S, Monick MM, Lovan N, Powers L, Gerke A, Hunninghake GW (2010) Vitamin D decreases respiratory syncytial virus induction of NF-kappaB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state. J Immunol 184:965-974
14. Grant WB (2008) Variations in vitamin D production could possibly explain the seasonality of childhood respiratory infections in Hawaii. Pediatr Infect Dis J 27:853
15. Ginde AA, Mansbach JM, Camargo CA (2009) Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med 169:384-390
16. Cannell JJ, Vieth R, Umhau JC, Holick MF, Grant WB (2006) Epidemic influenza and vitamin D. Epidemiol Infect 134:1129-1140
17. Ziegler T, Hall H, Sanchez-Fauquier A, Gamble WC, Cox NJ (1995) Type- and subtype-specific detection of influenza viruses in clinical specimens by rapid culture assay. J Clin Microbiol 33:318-321
18. Wayse V, Yousafzai A, Mogale K, Filteau S (2004) Association of subclinical vitamin D deficiency with severe acute lower respiratory infection in Indian children under 5 y. Eur J Clin Nutr 58:563-567
19. Ichinohe T, Pang IKS, Iwasaki A (2010) Influenza virus activates inflammasomes via its intracellular M2 channel. Nat Immunol 11(5):404-410
20. Cunningham-Rundles S, McNeeley DF, Moon A (2005) Mechanisms of nutrient modulation of the immune response. J Allergy Clin Immunol 115:1119-1128
21. Allsup SJ, Shenkin A, Gosney MA (2002) Difficulties of recruitment for a randomized controlled trial involving influenza vaccination in healthy older people. Gerontology 48:170-173
22. Cannell JJ, Zasloff M, Garland CF, Scragg R, Giovannucci E (2008) On the epidemiology of influenza. Virol J 5:29
23. Hansdottir S, Monick MM, Hinde SL, Lovan N, Look DC, Hunninghake GW (2008) Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol 181:7090-7099
24. Hansdottir S, Monick MM, Lovan N, Powers L, Gerke A, Hunninghake GW (2010) Vitamin D decreases respiratory syncytial virus induction of NF-kappaB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state. J Immunol 184:965-974
25. Rossman JS, Lamb RA (2009) Autophagy, apoptosis, and the influenza virus M2 protein. Cell Host Microbe 6:299-300
26. Zhou Z, Jiang X, Liu D, Fan Z, Hu X, Yan J, Wang M, Gao GF (2009) Autophagy is involved in influenza A virus replication. Autophagy 5(3):321-328
27. Gannage M, Dormann D, Albrecht R, Dengjel J, Torossi T, Rämer PC, Lee M, Strowig T, Arrey F, Conenello G, Pypaert M, Andersen J, García-Sastre A, Münz C (2009) Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 6:367-380
28. Korn T, Oukka M, Kuchroo V, Bettelli E (2007) Th17 cells: effector T cells with inflammatory properties. Semin Immunol 19:362-371
29. McGill J, Heusel JW, Legge KL (2009) Innate immune control and regulation of influenza virus infections. J Leukoc Biol 86:803-812
30. Miossec P, Korn T, Kuchroo VK (2009) Interleukin-17 and Type 17 helper T cells. N Engl J Med 361:888-898
31. To KK, Hung IF, Li IW, Lee KL, Koo CK, Yan WW, Liu R, Ho KY, Chu KH, Watt CL, Luk WK, Lai KY, Chow FL, Mok T, Buckley T, Chan JF, Wong SS, Zheng B, Chen H, Lau CC, Tse H, Cheng VC, Chan KH, Yuen KY (2010) Pandemic H1N1 Study Group. Delayed clearance of viral load and marked cytokine activation in severe cases of pandemic H1N1 2009 influenza virus infection. Clin Infect Dis 50:850-859
32. Hagau N, Slavcovici A, Gonganau DN, Oltean S, Dirzu DS, Brezoszki ES, Maxim M, Ciuce C, Mlesnite M, Gavrus RL, Laslo C, Hagau R, Petrescu M, Studnicska DM (2010) Clinical aspects and cytokine response in severe H1N1 influenza A virus infection. Crit Care 14:203
33. Phung TT, Sugamata R, Uno K, Aratani Y, Ozato K, Kawachi S, Nguyen LT, Nakayama T, Suzuki K (2011) Key role of RANTES (regulated upon activation normal T-cell expressed and secreted), nonstructural protein1 and myeloperoxidase in cytokine storm induced by influenza virus PR-8(A/H1N1) infection in A549 bronchial epithelial cells. Microbiol Immunol 55:874-884
34. Uchide N, Toyoda H (2011) Antioxidant therapy as a potential approach to severe influenza-associated complications. Molecules 16:2032-2052
35. Mark NK, Leung CY, Wei XY, Shen XL, Wong RNS, Leung KN (2004) Inhibition of RANTES expression by indirubin in influenza virus infected human bronchial epithelial cells. Biochem Pharmacol 67:167-174
36. Kunzi MS, Pitha PM (2003) Interferon targeted genes in host defense. Autoimmunity 36:457-461
37. Healy KD, Vanhooke JL, Prahl JM, DeLuca HF (2005) Parathyroid hormone decreases renal vitamin D expression in vivo Proc. Natl Acad Sci USA 102:4724-4728
38. Sadeghi K, Wessner B, Laggner U, Ploder M, Tamandl D, Friedl J, Zügel U, Steinmeyer A, Pollak A, Roth E, Boltz-Nitulescu G, Spittler A (2006) Vitamin-D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns. Eur J Immunol 36:361-370
39. Reinhardt TA, Horst RL (1990) Parathyroid hormone down-regulates 1,25-dihydroxyvitamin D receptors (VDR) and VDR messenger ribonucleic acid in vitro and blocks homologous up-regulation of VDR in vivo. Endocrinology 127:942-948
40. Klaus G, May T, Hügel U, Von EB, Rodriguez J, Fernandez P, Reichrath J, Ritz E, Mehls O (1997) Parathyroid hormone prevents 1,25 (OH)2D3 induced down-regulation of the vitamin D receptor in growth plate chondrocytes in vitro. Kidney Int 52:45-51
41. Sabetta JR, DePetrillo P, Cipriani RJ, Smardin J, Burns LA, Landry ML (2010) Serum 25-hydroxyvitamin D and the incidence of acute viral respiratory tract infections in healthy adults. PLoS ONE 5(6):e11088