Short-term psychosocial stress protects photoreceptors from damage via corticosterone-mediated activation of the AKT pathway

Experimental Neurology

Volumn 252, Issue , 2014, Pages 28-36

  Forkwa, Tembei K ^a   Neumann, Inga D ^a   Tamm, Ernst R ^a   Ohlmann, Andreas ^a   Reber, Stefan O ^a,b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

AKT signaling; Apoptosis; Chronic subordinate colony housing; Glucocorticoids; Hypothalamo pituitary adrenocortical axis; Light induced photoreceptor damage; Neuroprotection; Photoreceptor degeneration; Psychosocial stress

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID; PROTEIN KINASE B; TRICIRIBINE;

ADRENALECTOMY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL HOUSING; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HORMONE SUBSTITUTION; LIGHT DAMAGE; LIGHT EXPOSURE; MALE; MENTAL STRESS; MOUSE; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTORECEPTOR CELL; PRIORITY JOURNAL; RETINA; SIGNAL TRANSDUCTION; WHITE LIGHT;

AKT SIGNALING; APOPTOSIS; CHRONIC SUBORDINATE COLONY HOUSING; GLUCOCORTICOIDS; HYPOTHALAMO-PITUITARY-ADRENOCORTICAL AXIS; LIGHT-INDUCED PHOTORECEPTOR DAMAGE; NEUROPROTECTION; PHOTORECEPTOR DEGENERATION; PSYCHOSOCIAL STRESS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; CORTICOSTERONE; DISEASE MODELS, ANIMAL; ENDOTHELIN-2; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; LEUKEMIA INHIBITORY FACTOR; LIGHT; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEUROGLIA; PHOTORECEPTOR CELLS, VERTEBRATE; RETINAL DEGENERATION; RIBONUCLEOSIDES; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; TIME FACTORS;

EID: 84890057392     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.11.016     Document Type: Article

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