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Volumn 123, Issue 12, 2013, Pages 5258-5268

JUNB/AP-1 controls IFN-γ during inflammatory liver disease

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CONCANAVALIN A; GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1;

EID: 84890056439     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI70405     Document Type: Article
Times cited : (46)

References (61)
  • 1
    • 84875810895 scopus 로고    scopus 로고
    • Mouse models for liver cancer
    • Bakiri L, Wagner EF. Mouse models for liver cancer. Mol Oncol. 2013;7(2):206-223
    • (2013) Mol Oncol , vol.7 , Issue.2 , pp. 206-223
    • Bakiri, L.1    Wagner, E.F.2
  • 3
    • 84867212593 scopus 로고    scopus 로고
    • Chronic inflammation, immune escape, and oncogenesis in the liver: A unique neighborhood for novel intersections
    • Stauffer JK, Scarzello AJ, Jiang Q, Wiltrout RH. Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections. Hepatology. 2012;56(4):1567-1574
    • (2012) Hepatology , vol.56 , Issue.4 , pp. 1567-1574
    • Stauffer, J.K.1    Scarzello, A.J.2    Jiang, Q.3    Wiltrout, R.H.4
  • 4
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. 2007;132(7):2557-2576
    • (2007) Gastroenterology , vol.132 , Issue.7 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 5
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • Rehermann B, Nascimbeni M. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol. 2005;5(3):215-229
    • (2005) Nat Rev Immunol , vol.5 , Issue.3 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 6
    • 36749069393 scopus 로고    scopus 로고
    • Interferons at age 50: Past, current and future impact on biomedicine
    • Borden EC, et al. Interferons at age 50: past, current and future impact on biomedicine. Nat Rev Drug Discov. 2007;6(12):975-990
    • (2007) Nat Rev Drug Discov , vol.6 , Issue.12 , pp. 975-990
    • Borden, E.C.1
  • 7
    • 55149102403 scopus 로고    scopus 로고
    • Inborn errors of interferon (IFN)- Mediated immunity in humans: Insights into the respective roles of IFN-α/β, IFN-γ, and IFN-λ in host defense
    • Zhang SY, et al. Inborn errors of interferon (IFN)- mediated immunity in humans: insights into the respective roles of IFN-α/β, IFN-γ, and IFN-λ in host defense. Immunol Rev. 2008;226:29-40
    • (2008) Immunol Rev , vol.226 , pp. 29-40
    • Zhang, S.Y.1
  • 9
    • 0242416575 scopus 로고    scopus 로고
    • Cytokines and transcription factors that regulate T helper cell differentiation: New players and new insights
    • Agnello D, et al. Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol. 2003;23(3):147-161
    • (2003) J Clin Immunol , vol.23 , Issue.3 , pp. 147-161
    • Agnello, D.1
  • 10
    • 35549003579 scopus 로고    scopus 로고
    • Regulation of interferon-γ during innate and adaptive immune responses
    • Schoenborn JR, Wilson CB. Regulation of interferon-γ during innate and adaptive immune responses. Adv Immunol. 2007;96:41-101
    • (2007) Adv Immunol , vol.96 , pp. 41-101
    • Schoenborn, J.R.1    Wilson, C.B.2
  • 11
    • 0034596944 scopus 로고    scopus 로고
    • Natural killer T cell activation inhibits hepatitis B virus replication in vivo
    • Kakimi K, Guidotti LG, Koezuka Y, Chisari FV. Natural killer T cell activation inhibits hepatitis B virus replication in vivo. J Exp Med. 2000;192(7):921-930
    • (2000) J Exp Med , vol.192 , Issue.7 , pp. 921-930
    • Kakimi, K.1    Guidotti, L.G.2    Koezuka, Y.3    Chisari, F.V.4
  • 12
    • 84863707404 scopus 로고    scopus 로고
    • Hepatitis B virus-Induced lipid alterations contribute to natural killer T cell-Dependent protective immunity
    • Zeissig S, et al. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nat Med. 2012;18(7):1060-1068
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1060-1068
    • Zeissig, S.1
  • 13
    • 84871916306 scopus 로고    scopus 로고
    • Immunoregulation of hepatitis B virus infection-Rationale and clinical application
    • Ishikawa T. Immunoregulation of hepatitis B virus infection-rationale and clinical application. Nagoya J Med Sci. 2012;74(3-4):217-232
    • (2012) Nagoya J Med Sci , vol.74 , Issue.3-4 , pp. 217-232
    • Ishikawa, T.1
  • 15
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: A double-Edged sword in tumorigenesis
    • Eferl R, Wagner EF. AP-1: a double-edged sword in tumorigenesis. Nat Rev Cancer. 2003;3(11):859-868
    • (2003) Nat Rev Cancer , vol.3 , Issue.11 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 16
    • 28544434439 scopus 로고    scopus 로고
    • Fos/AP-1 proteins in bone and the immune system
    • Wagner EF, Eferl R. Fos/AP-1 proteins in bone and the immune system. Immunol Rev. 2005;208:126-140
    • (2005) Immunol Rev , vol.208 , pp. 126-140
    • Wagner, E.F.1    Eferl, R.2
  • 17
    • 0029052324 scopus 로고
    • Negative transcriptional regulation of the interferon-Gamma promoter by glucocorticoids and dominant negative mutants of c-Jun
    • Cippitelli M, et al. Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun. J Biol Chem. 1995;270(21):12548-12556
    • (1995) J Biol Chem , vol.270 , Issue.21 , pp. 12548-12556
    • Cippitelli, M.1
  • 18
    • 0027936441 scopus 로고
    • AP-1 transcriptional activity requires both T-Cell receptor-Mediated and co-Stimulatory signals in primary T lymphocytes
    • Rincon M, Flavell RA. AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. EMBO J. 1994;13(18):4370-4381
    • (1994) EMBO J , vol.13 , Issue.18 , pp. 4370-4381
    • Rincon, M.1    Flavell, R.A.2
  • 19
    • 34447629920 scopus 로고    scopus 로고
    • Dimer composition and promoter context contribute to functional cooperation between AP-1 and NFAT
    • Wisniewska MB, Ameyar-Zazoua M, Bakiri L, Kaminska B, Yaniv M, Weitzman JB. Dimer composition and promoter context contribute to functional cooperation between AP-1 and NFAT. J Mol Biol. 2007;371(3):569-576
    • (2007) J Mol Biol , vol.371 , Issue.3 , pp. 569-576
    • Wisniewska, M.B.1    Ameyar-Zazoua, M.2    Bakiri, L.3    Kaminska, B.4    Yaniv, M.5    Weitzman, J.B.6
  • 20
    • 0344196985 scopus 로고    scopus 로고
    • Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation
    • Li B, Tournier C, Davis RJ, Flavell RA. Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J. 1999; 18(2):420-432
    • (1999) EMBO J , vol.18 , Issue.2 , pp. 420-432
    • Li, B.1    Tournier, C.2    Davis, R.J.3    Flavell, R.A.4
  • 21
    • 1942439156 scopus 로고    scopus 로고
    • JunD regulates lymphocyte proliferation and T helper cell cytokine expression
    • Meixner A, Karreth F, Kenner L, Wagner EF. JunD regulates lymphocyte proliferation and T helper cell cytokine expression. EMBO J. 2004;23(6):1325-1335
    • (2004) EMBO J , vol.23 , Issue.6 , pp. 1325-1335
    • Meixner, A.1    Karreth, F.2    Kenner, L.3    Wagner, E.F.4
  • 22
    • 72749114289 scopus 로고    scopus 로고
    • TNFα shedding and epidermal inflammation are controlled by jun proteins
    • Guinea-Viniegra J, et al. TNFα shedding and epidermal inflammation are controlled by Jun proteins. Genes Dev. 2009;23(22):2663-2674
    • (2009) Genes Dev , vol.23 , Issue.22 , pp. 2663-2674
    • Guinea-Viniegra, J.1
  • 23
    • 48649094094 scopus 로고    scopus 로고
    • Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation
    • Meixner A, et al. Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation. Nat Cell Biol. 2008;10(8):1003-1011
    • (2008) Nat Cell Biol , vol.10 , Issue.8 , pp. 1003-1011
    • Meixner, A.1
  • 24
    • 0036463679 scopus 로고    scopus 로고
    • JunB can substitute for Jun in mouse devel-Opment and cell proliferation
    • Passegue E, Jochum W, Behrens A, Ricci R, Wagner EF. JunB can substitute for Jun in mouse devel-opment and cell proliferation. Nat Genet. 2002; 30(2):158-166
    • (2002) Nat Genet , vol.30 , Issue.2 , pp. 158-166
    • Passegue, E.1    Jochum, W.2    Behrens, A.3    Ricci, R.4    Wagner, E.F.5
  • 25
    • 36749084608 scopus 로고    scopus 로고
    • Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-Dependent expression of inducible nitric oxide synthase
    • Hasselblatt P, Rath M, Komnenovic V, Zatloukal K, Wagner EF. Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase. Proc Natl Acad Sci U S A. 2007;104(43):17105- 17110
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.43 , pp. 17105-17110
    • Hasselblatt, P.1    Rath, M.2    Komnenovic, V.3    Zatloukal, K.4    Wagner, E.F.5
  • 26
    • 0026643743 scopus 로고
    • T cell-Dependent experimental liver injury in mice inducible by concanavalin A
    • Tiegs G, Hentschel J, Wendel A. A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J Clin Invest. 1992;90(1):196-203
    • (1992) J Clin Invest , vol.90 , Issue.1 , pp. 196-203
    • Tiegs, G.1    Hentschel, J.2    Wendel, A.A.3
  • 27
    • 0033694155 scopus 로고    scopus 로고
    • Importance of kupffer cells for T-Cell-Dependent liver injury in mice
    • Schumann J, et al. Importance of Kupffer cells for T-cell-dependent liver injury in mice. Am J Pathol. 2000;157(5):1671-1683
    • (2000) Am J Pathol , vol.157 , Issue.5 , pp. 1671-1683
    • Schumann, J.1
  • 28
    • 0042624818 scopus 로고    scopus 로고
    • A monoclonal antibody to the alpha2 domain of murine major histocompatibility complex class 1 that specifically kills activated lymphocytes and blocks liver damage in the concanavalin A hepatitis model
    • Matsuoka S, et al. A monoclonal antibody to the alpha2 domain of murine major histocompatibility complex class 1 that specifically kills activated lymphocytes and blocks liver damage in the concanavalin A hepatitis model. J Exp Med. 2003; 198(3):497-503
    • (2003) J Exp Med , vol.198 , Issue.3 , pp. 497-503
    • Matsuoka, S.1
  • 29
    • 58149388313 scopus 로고    scopus 로고
    • Superoxide produced by kupffer cells is an essential effector in concanavalin A-Induced hepatitis in mice
    • Nakashima H, et al. Superoxide produced by Kupffer cells is an essential effector in concanavalin A-induced hepatitis in mice. Hepatology. 2008;48(6):1979-1988
    • (2008) Hepatology , vol.48 , Issue.6 , pp. 1979-1988
    • Nakashima, H.1
  • 31
    • 0344496062 scopus 로고    scopus 로고
    • IKKbeta is required for prevention of apoptosis mediated by cell-Bound but not by circulating TNFalpha
    • Maeda S, Chang L, Li ZW, Luo JL, Leffert H, Karin M. IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha. Immunity. 2003;19(5):725-737
    • (2003) Immunity , vol.19 , Issue.5 , pp. 725-737
    • Maeda, S.1    Chang, L.2    Li, Z.W.3    Luo, J.L.4    Leffert, H.5    Karin, M.6
  • 32
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-Stranded RNA and activation of NF-κB by toll-Like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature. 2001; 413(6857):732-738
    • (2001) Nature , vol.413 , Issue.6857 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 33
    • 72949093140 scopus 로고    scopus 로고
    • The β2 integrin CD11b attenuates polyinosinic:Polycytidylic acid-Induced hepatitis by negatively regulating natural killer cell functions
    • Zhang M, et al. The β2 integrin CD11b attenuates polyinosinic:polycytidylic acid-induced hepatitis by negatively regulating natural killer cell functions. Hepatology. 2009;50(5):1606-1616
    • (2009) Hepatology , vol.50 , Issue.5 , pp. 1606-1616
    • Zhang, M.1
  • 34
    • 1842833641 scopus 로고    scopus 로고
    • Role of NKT cells and alpha-Galactosyl ceramide
    • Shimosaka A. Role of NKT cells and alpha-galactosyl ceramide. Int J Hematol. 2002;76(suppl 1):277-279
    • (2002) Int J Hematol , vol.76 , Issue.SUPPL.1 , pp. 277-279
    • Shimosaka, A.1
  • 35
    • 22544445833 scopus 로고    scopus 로고
    • α-Galactosylceramideinduced liver injury in mice is mediated by TNF-α but independent of kupffer cells
    • Biburger M, Tiegs G. α-Galactosylceramideinduced liver injury in mice is mediated by TNF-α but independent of Kupffer cells. J Immunol. 2005; 175(3):1540-1550
    • (2005) J Immunol , vol.175 , Issue.3 , pp. 1540-1550
    • Biburger, M.1    Tiegs, G.2
  • 36
    • 77956921833 scopus 로고    scopus 로고
    • A critical role for IFN regulatory factor 1 in NKT cell-Mediated liver injury induced by α-Galactosylceramide
    • Cao Z, Dhupar R, Cai C, Li P, Billiar TR, Geller DA. A critical role for IFN regulatory factor 1 in NKT cell-mediated liver injury induced by α-galactosylceramide. J Immunol. 2010;185(4):2536-2543
    • (2010) J Immunol , vol.185 , Issue.4 , pp. 2536-2543
    • Cao, Z.1    Dhupar, R.2    Cai, C.3    Li, P.4    Billiar, T.R.5    Geller, D.A.6
  • 37
    • 34249794259 scopus 로고    scopus 로고
    • IFN-γ protects cerulein-Induced acute pancreatitis by repressing NF-κB activation
    • Hayashi T, Ishida Y, Kimura A, Iwakura Y, Mukaida N, Kondo T. IFN-γ protects cerulein-induced acute pancreatitis by repressing NF-κB activation. J Immunol. 2007;178(11):7385-7394
    • (2007) J Immunol , vol.178 , Issue.11 , pp. 7385-7394
    • Hayashi, T.1    Ishida, Y.2    Kimura, A.3    Iwakura, Y.4    Mukaida, N.5    Kondo, T.6
  • 38
    • 0028964916 scopus 로고
    • Identification and purification of human stat proteins activated in response to interleukin-2
    • Hou J, Schindler U, Henzel WJ, Wong SC, Mc Knight SL. Identification and purification of human Stat proteins activated in response to interleukin-2. Immunity. 1995;2(4):321-329
    • (1995) Immunity , vol.2 , Issue.4 , pp. 321-329
    • Hou, J.1    Schindler, U.2    Henzel, W.J.3    Wong, S.C.4    Mc Knight, S.L.5
  • 39
    • 0027090310 scopus 로고
    • Activation of transcription by IFN-Gamma: Tyrosine phosphorylation of a 91-kD DNA binding protein
    • Shuai K, Schindler C, Prezioso VR, Darnell JE. Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science. 1992;258(5089):1808-1812
    • (1992) Science , vol.258 , Issue.5089 , pp. 1808-1812
    • Shuai, K.1    Schindler, C.2    Prezioso, V.R.3    Darnell, J.E.4
  • 40
    • 16844387413 scopus 로고    scopus 로고
    • The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury
    • Klein C, et al. The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury. J Clin Invest. 2005;115(4):860-869
    • (2005) J Clin Invest , vol.115 , Issue.4 , pp. 860-869
    • Klein, C.1
  • 41
    • 0035008978 scopus 로고    scopus 로고
    • SOCS-1/SSI-1-Deficient NKT cells participate in severe hepatitis through dysregulated cross-Talk inhibition of IFN-γ and IL-4 signaling in vivo
    • Naka T, et al. SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-γ and IL-4 signaling in vivo. Immunity. 2001;14(5):535-545
    • (2001) Immunity , vol.14 , Issue.5 , pp. 535-545
    • Naka, T.1
  • 42
    • 0035067108 scopus 로고    scopus 로고
    • Requirement for STAT1 in LPS-Induced gene expression in macrophages
    • Ohmori Y, Hamilton TA. Requirement for STAT1 in LPS-induced gene expression in macrophages. J Leukoc Biol. 2001;69(4):598-604
    • (2001) J Leukoc Biol , vol.69 , Issue.4 , pp. 598-604
    • Ohmori, Y.1    Hamilton, T.A.2
  • 43
    • 0037414809 scopus 로고    scopus 로고
    • The transcriptional coactivator CREB-Binding protein cooperates with STAT1 and NF-κB for synergistic transcriptional activation of the CXC ligand 9/monokine induced by interferon-γ gene
    • Hiroi M, Ohmori Y. The transcriptional coactivator CREB-binding protein cooperates with STAT1 and NF-κB for synergistic transcriptional activation of the CXC ligand 9/monokine induced by interferon-γ gene. J Biol Chem. 2003;278(1):651-660
    • (2003) J Biol Chem , vol.278 , Issue.1 , pp. 651-660
    • Hiroi, M.1    Ohmori, Y.2
  • 44
    • 80052010610 scopus 로고    scopus 로고
    • Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse
    • Tsuge M, et al. Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse. PLoS One. 2011;6(8):e23856
    • (2011) PLoS One , vol.6 , Issue.8
    • Tsuge, M.1
  • 46
    • 33748349403 scopus 로고    scopus 로고
    • The innate interferon gamma response of BALB/c and C57BL/6 mice to in vitro burkholderia pseudomallei infection
    • Koo GC, Gan YH. The innate interferon gamma response of BALB/c and C57BL/6 mice to in vitro Burkholderia pseudomallei infection. BMC Immunol. 2006;7:19
    • (2006) BMC Immunol , vol.7 , pp. 19
    • Koo, G.C.1    Gan, Y.H.2
  • 47
    • 44449090072 scopus 로고    scopus 로고
    • Sumoylation regulates the transcriptional activity of junB in T lymphocytes
    • Garaude J, et al. SUMOylation regulates the transcriptional activity of JunB in T lymphocytes. J Immunol. 2008;180(9):5983-5990
    • (2008) J Immunol , vol.180 , Issue.9 , pp. 5983-5990
    • Garaude, J.1
  • 48
    • 0025190716 scopus 로고
    • Interleukin 2-Induced proliferation of murine natural killer cells in vivo
    • Biron CA, Young HA, Kasaian MT. Interleukin 2-induced proliferation of murine natural killer cells in vivo. J Exp Med. 1990;171(1):173-188
    • (1990) J Exp Med , vol.171 , Issue.1 , pp. 173-188
    • Biron, C.A.1    Young, H.A.2    Kasaian, M.T.3
  • 49
    • 44649178270 scopus 로고    scopus 로고
    • Janus-kinase-3-Dependent signals induce chromatin remodeling at the ifng locus during T helper 1 cell differentiation
    • Shi M, Lin TH, Appell KC, Berg LJ. Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation. Immunity. 2008;28(6):763-773
    • (2008) Immunity , vol.28 , Issue.6 , pp. 763-773
    • Shi, M.1    Lin, T.H.2    Appell, K.C.3    Berg, L.J.4
  • 50
    • 0037462454 scopus 로고    scopus 로고
    • Liver tumor development
    • c-Jun antagonizes the proapoptotic activity of p53
    • Eferl R, et al. Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell. 2003;112(2):181-192
    • (2003) Cell , vol.112 , Issue.2 , pp. 181-192
    • Eferl, R.1
  • 51
    • 0033634878 scopus 로고    scopus 로고
    • JunD protects cells from p53-Dependent senescence and apoptosis
    • Weitzman JB, Fiette L, Matsuo K, Yaniv M. JunD protects cells from p53-dependent senescence and apoptosis. Mol Cell. 2000;6(5):1109-1119
    • (2000) Mol Cell , vol.6 , Issue.5 , pp. 1109-1119
    • Weitzman, J.B.1    Fiette, L.2    Matsuo, K.3    Yaniv, M.4
  • 53
    • 0038676902 scopus 로고    scopus 로고
    • STAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activation
    • Xu W, et al. STAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activation. Am J Physiol Lung Cell Mol Physiol. 2003;285(1):L137-L148
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285 , Issue.1
    • Xu, W.1
  • 54
    • 33847740720 scopus 로고    scopus 로고
    • A novel c-Jun-Dependent signal transduction pathway necessary for the transcriptional activation of interferon γ response genes
    • Gough DJ, et al. A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon γ response genes. J Biol Chem. 2007;282(2):938-946
    • (2007) J Biol Chem , vol.282 , Issue.2 , pp. 938-946
    • Gough, D.J.1
  • 55
    • 79955549815 scopus 로고    scopus 로고
    • CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-Mediated hepatitis
    • Erhardt A, et al. CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis. J Immunol. 2011; 186(9):5284-5293
    • (2011) J Immunol , vol.186 , Issue.9 , pp. 5284-5293
    • Erhardt, A.1
  • 56
    • 58249093873 scopus 로고    scopus 로고
    • Induction of hepatitis by JNK-Mediated expression of TNF-α
    • Das M, Sabio G, Jiang F, Rincon M, Flavell RA, Davis RJ. Induction of hepatitis by JNK-mediated expression of TNF-α. Cell. 2009;136(2):249-260
    • (2009) Cell , vol.136 , Issue.2 , pp. 249-260
    • Das, M.1    Sabio, G.2    Jiang, F.3    Rincon, M.4    Flavell, R.A.5    Davis, R.J.6
  • 57
    • 0343924357 scopus 로고    scopus 로고
    • Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
    • Gale MJ, et al. Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein. Virology. 1997;230(2):217-227
    • (1997) Virology , vol.230 , Issue.2 , pp. 217-227
    • Gale, M.J.1
  • 58
    • 67049158197 scopus 로고    scopus 로고
    • Impaired interferon signaling is a common immune defect in human cancer
    • Critchley-Thorne RJ, et al. Impaired interferon signaling is a common immune defect in human cancer. Proc Natl Acad Sci U S A. 2009;106(22):9010-9015
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.22 , pp. 9010-9015
    • Critchley-Thorne, R.J.1
  • 59
    • 84872559040 scopus 로고    scopus 로고
    • The immunosuppressive tumour network: Myeloid-Derived suppressor cells, regulatory T cells and natural killer T cells
    • Lindau D, Gielen P, Kroesen M, Wesseling P, Adema GJ. The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells. Immunology. 2013; 138(2):105-115
    • (2013) Immunology , vol.138 , Issue.2 , pp. 105-115
    • Lindau, D.1    Gielen, P.2    Kroesen, M.3    Wesseling, P.4    Adema, G.J.5
  • 60
    • 84858784892 scopus 로고    scopus 로고
    • Targeting natural killer cells and natural killer T cells in cancer
    • Vivier E, Ugolini S, Blaise D, Chabannon C, Brossay L. Targeting natural killer cells and natural killer T cells in cancer. Nat Rev Immunol. 2012;12(4):239-252
    • (2012) Nat Rev Immunol , vol.12 , Issue.4 , pp. 239-252
    • Vivier, E.1    Ugolini, S.2    Blaise, D.3    Chabannon, C.4    Brossay, L.5
  • 61
    • 84874192617 scopus 로고    scopus 로고
    • T-Helper-1-Cell cytokines drive cancer into senescence
    • Braumuller H, et al. T-helper-1-cell cytokines drive cancer into senescence. Nature. 2013; 494(7437):361-365
    • (2013) Nature , vol.494 , Issue.7437 , pp. 361-365
    • Braumuller, H.1


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