Comparison of the membrane proteome of virulent Mycobacterium tuberculosis and the attenuated Mycobacterium bovis BCG vaccine strain by label-free quantitative proteomics

Journal of Proteome Research

Volumn 12, Issue 12, 2013, Pages 5463-5474

  Gunawardena, Harsha P ^a   Feltcher, Meghan E ^a   Wrobel, John A ^a   Gu, Sheng ^a,b   Braunstein, Miriam ^a   Chen, Xian ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b BIOGEN   (United States)

Author keywords

1 D sodium dodecyl sulfate polyacrylamide gel electrophoresis (1D SDS PAGE); label free quantitation (LFQ); liquid chromatography mass spectrometry mass spectrometry (LC MS MS); membrane proteomes; Mycobacterium bovis (BCG); Mycobacterium tuberculosis (MTB); regions of difference (RD)

Indexed keywords

BCG VACCINE; MEMBRANE PROTEIN; PEPTIDE DERIVATIVE; PROTEOME; BACTERIAL PROTEIN; PEPTIDE; TRYPSIN;

ACCURACY; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; GENOMICS; IMMUNOBLOTTING; ION PAIR CHROMATOGRAPHY; LABEL FREE QUANTITATIVE PROTEOMICS; LIQUID CHROMATOGRAPHY; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEOMICS; TANDEM MASS SPECTROMETRY; VALIDATION STUDY; CELL MEMBRANE; CHEMISTRY; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENE LOCUS; GENETICS; ISOLATION AND PURIFICATION; MOLECULAR GENETICS; PATHOGENICITY; PROCEDURES; PROTEIN DEGRADATION; VIRULENCE;

BACTERIAL PROTEINS; CELL MEMBRANE; CHROMATOGRAPHY, LIQUID; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC LOCI; IMMUNOBLOTTING; MEMBRANE PROTEINS; MOLECULAR SEQUENCE ANNOTATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; PEPTIDES; PROTEOLYSIS; PROTEOME; PROTEOMICS; TANDEM MASS SPECTROMETRY; TRYPSIN; VIRULENCE;

EID: 84890023185     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr400334k     Document Type: Article

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