HIV-1 Vpr induces adipose dysfunction in vivo through reciprocal effects on PPAR/GR co-regulation

Science Translational Medicine

Volumn 5, Issue 213, 2013, Pages

  Agarwal, Neeti ^a   Iyer, Dinakar ^a   Patel, Sanjeet G ^a,g   Sekhar, Rajagopal V ^a,b   Phillips, Terry M ^c   Schubert, Ulrich ^d   Oplt, Toni ^a   Buras, Eric D ^a,h   Samson, Susan L ^a,b   Couturier, Jacob ^e   Lewis, Dorothy E ^e   Rodriguez Barradas, Maria C ^a   Jahoor, Farook ^a   Kino, Tomoshige ^c   Kopp, Jeffrey B ^f   Balasubramanyam, Ashok ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b BEN TAUB GENERAL HOSPITAL   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e UNIVERSITY OF TEXAS   (United States)

^f NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^g UCLA MEDICAL CENTER   (United States)

^h UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; GLUCOCORTICOID RECEPTOR; HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL INFILTRATION; DOWN REGULATION; FAT MASS; FATTY LIVER; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HYPERGLYCEMIA; INSULIN RESISTANCE; LIPOLYSIS; LIVER CELL; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENE; VIRUS LOAD;

3T3-L1 CELLS; ANIMALS; CHROMATOGRAPHY, THIN LAYER; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE PRODUCTS, VPR; HIV-1; HUMANS; IMMUNOBLOTTING; MALE; MICE; MICE, TRANSGENIC; PPAR ALPHA; PPAR GAMMA; RECEPTORS, GLUCOCORTICOID;

EID: 84890021241     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3007148     Document Type: Article

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