메뉴 건너뛰기




Volumn 98, Issue 12, 2013, Pages 4863-4871

Endurance exercise training up-regulates lipolytic proteins and reduces triglyceride content in skeletal muscle of obese subjects

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; GLUCOSE; HORMONE SENSITIVE LIPASE; LIPOLYTIC PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; PERILIPIN; PERILIPIN 2; PERILIPIN 3; PERILIPIN 5; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

EID: 84889810598     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-2058     Document Type: Article
Times cited : (67)

References (40)
  • 1
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: Common threads and missing links
    • Samuel VT, Shulman GI. Mechanisms for insulin resistance: common threads and missing links. Cell. 2012;148:852-871.
    • (2012) Cell , vol.148 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 2
    • 4644347353 scopus 로고    scopus 로고
    • Use of intramuscular triacylglycerol as a substrate source during exercise in humans
    • van Loon LJ. Use of intramuscular triacylglycerol as a substrate source during exercise in humans. J Appl Physiol. 2004;97:1170- 1187.
    • (2004) J Appl Physiol , vol.97 , pp. 1170-1187
    • Van Loon, L.J.1
  • 3
    • 0035217707 scopus 로고    scopus 로고
    • Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurancetrained athletes
    • Goodpaster BH, He J, Watkins S, Kelley DE. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurancetrained athletes. J Clin Endocrinol Metab. 2001;86:5755-5761.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5755-5761
    • Goodpaster, B.H.1    He, J.2    Watkins, S.3    Kelley, D.E.4
  • 4
    • 84868326874 scopus 로고    scopus 로고
    • Prolonged exercise training increases intramuscular lipid content and perilipin 2 expression in type 1 muscle fibers of patients with type 2 diabetes
    • Shaw CS, Shepherd SO, Wagenmakers AJ, Hansen D, Dendale P, van Loon LJ. Prolonged exercise training increases intramuscular lipid content and perilipin 2 expression in type 1 muscle fibers of patients with type 2 diabetes.AmJ Physiol Endocrinol Metab. 2012; 303:E1158-E1165.
    • (2012) AmJ Physiol Endocrinol Metab , vol.303
    • Shaw, C.S.1    Shepherd, S.O.2    Wagenmakers, A.J.3    Hansen, D.4    Dendale, P.5    Van Loon, L.J.6
  • 5
    • 69949089944 scopus 로고    scopus 로고
    • Influence of gender, obesity, and muscle lipase activity on intramyocellular lipids in sedentary individuals
    • Moro C, Galgani JE, Luu L, et al. Influence of gender, obesity, and muscle lipase activity on intramyocellular lipids in sedentary individuals. J Clin Endocrinol Metab. 2009;94:3440-3447.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3440-3447
    • Moro, C.1    Galgani, J.E.2    Luu, L.3
  • 6
    • 0038697895 scopus 로고    scopus 로고
    • Intramyocellular lipids: Anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity
    • Thamer C, Machann J, Bachmann O, et al. Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity. J Clin Endocrinol Metab. 2003; 88:1785-1791.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1785-1791
    • Thamer, C.1    Machann, J.2    Bachmann, O.3
  • 7
    • 79959387473 scopus 로고    scopus 로고
    • Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans
    • Badin PM, Louche K, Mairal A, et al. Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans. Diabetes. 2011;60:1734-1742.
    • (2011) Diabetes , vol.60 , pp. 1734-1742
    • Badin, P.M.1    Louche, K.2    Mairal, A.3
  • 8
    • 78650069737 scopus 로고    scopus 로고
    • Skeletal muscle lipase content and activity in obesity and type 2 diabetes
    • Jocken JW, Moro C, Goossens GH, et al. Skeletal muscle lipase content and activity in obesity and type 2 diabetes. J Clin Endocrinol Metab. 2010;95:5449-5453.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 5449-5453
    • Jocken, J.W.1    Moro, C.2    Goossens, G.H.3
  • 9
    • 33646462136 scopus 로고    scopus 로고
    • Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
    • Haemmerle G, Lass A, Zimmermann R, et al. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science. 2006;312:734-737.
    • (2006) Science , vol.312 , pp. 734-737
    • Haemmerle, G.1    Lass, A.2    Zimmermann, R.3
  • 10
    • 30744477567 scopus 로고    scopus 로고
    • Adipocyte lipases and defect of lipolysis in human obesity
    • Langin D, Dicker A, Tavernier G, et al. Adipocyte lipases and defect of lipolysis in human obesity. Diabetes. 2005;54:3190-3197.
    • (2005) Diabetes , vol.54 , pp. 3190-3197
    • Langin, D.1    Dicker, A.2    Tavernier, G.3
  • 11
    • 84860290557 scopus 로고    scopus 로고
    • Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58
    • Badin PM, Loubière C, Coonen M, et al. Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58. J Lipid Res. 2012;53:839-848.
    • (2012) J Lipid Res , vol.53 , pp. 839-848
    • Badin, P.M.1    Loubière, C.2    Coonen, M.3
  • 12
    • 77249118270 scopus 로고    scopus 로고
    • The G0/G1 switch gene 2 regulates adipose ipolysis through association with adipose triglyceride lipase
    • Yang X, Lu X, Lombès M, et al. The G0/G1 switch gene 2 regulates adipose ipolysis through association with adipose triglyceride lipase. Cell Metab. 2010;11:194-205.
    • (2010) Cell Metab , vol.11 , pp. 194-205
    • Yang, X.1    Lu, X.2    Lombès, M.3
  • 13
    • 84863614584 scopus 로고    scopus 로고
    • Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation
    • Kuramoto K, Okamura T, Yamaguchi T, et al. Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation. J Biol Chem. 2012; 287:23852-23863.
    • (2012) J Biol Chem , vol.287 , pp. 23852-23863
    • Kuramoto, K.1    Okamura, T.2    Yamaguchi, T.3
  • 14
    • 84875856324 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier
    • Pollak NM, Schweiger M, Jaeger D, et al. Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier. J Lipid Res. 2013;54:1092-1102.
    • (2013) J Lipid Res , vol.54 , pp. 1092-1102
    • Pollak, N.M.1    Schweiger, M.2    Jaeger, D.3
  • 15
    • 84868020505 scopus 로고    scopus 로고
    • Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels
    • Bosma M, Hesselink MK, Sparks LM, et al. Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels. Diabetes. 2012;61:2679-2690.
    • (2012) Diabetes , vol.61 , pp. 2679-2690
    • Bosma, M.1    Hesselink, M.K.2    Sparks, L.M.3
  • 17
    • 84873839927 scopus 로고    scopus 로고
    • Physical activity, cardiorespiratory fitness, and exercise training in primary and secondary coronary prevention
    • Swift DL, Lavie CJ, Johannsen NM, et al. Physical activity, cardiorespiratory fitness, and exercise training in primary and secondary coronary prevention. Circ J. 2013;77:281-292.
    • (2013) Circ J , vol.77 , pp. 281-292
    • Swift, D.L.1    Lavie, C.J.2    Johannsen, N.M.3
  • 19
    • 35548961030 scopus 로고    scopus 로고
    • Lipid oxidation according to intensity and exercise duration in overweight men and women
    • Pillard F, Moro C, Harant I, et al. Lipid oxidation according to intensity and exercise duration in overweight men and women. Obesity (Silver Spring) 2007;15:2256-2262.
    • (2007) Obesity (Silver Spring) , vol.15 , pp. 2256-2262
    • Pillard, F.1    Moro, C.2    Harant, I.3
  • 20
    • 0016723939 scopus 로고
    • Percutaneous needle biopsy of skeletal muscle in physiological and clinical research
    • Bergstrom J. Percutaneous needle biopsy of skeletal muscle in physiological and clinical research. Scand J Clin Lab Invest. 1975;35: 609-616.
    • (1975) Scand J Clin Lab Invest , vol.35 , pp. 609-616
    • Bergstrom, J.1
  • 21
    • 84876250786 scopus 로고    scopus 로고
    • Enhanced skeletal muscle lipid oxidative efficiency in insulin-resistant vs insulin-sensitive nondiabetic, nonobese humans
    • Galgani JE, Vasquez K, Watkins G, et al. Enhanced skeletal muscle lipid oxidative efficiency in insulin-resistant vs insulin-sensitive nondiabetic, nonobese humans. J Clin Endocrinol Metab. 2013;98: E646-E653.
    • (2013) J Clin Endocrinol Metab , vol.98
    • Galgani, J.E.1    Vasquez, K.2    Watkins, G.3
  • 22
    • 84876251802 scopus 로고    scopus 로고
    • Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes
    • Sparks LM, Johannsen NM, Church TS, et al. Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes. J Clin Endocrinol Metab. 2013;98: 1694-1702.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 1694-1702
    • Sparks, L.M.1    Johannsen, N.M.2    Church, T.S.3
  • 23
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 1959;37:911-917.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 25
    • 84868026541 scopus 로고    scopus 로고
    • Exercise alleviates lipid-induced insulin resistance in human skeletal muscle-signaling interaction at the level of TBC1 domain family member 4
    • Pehmøller C, Brandt N, Birk JB, et al. Exercise alleviates lipid-induced insulin resistance in human skeletal muscle-signaling interaction at the level of TBC1 domain family member 4. Diabetes. 2012;61:2743-2752.
    • (2012) Diabetes , vol.61 , pp. 2743-2752
    • Pehmøller, C.1    Brandt, N.2    Birk, J.B.3
  • 26
    • 81355132716 scopus 로고    scopus 로고
    • Resistance exercise enhances the molecular signaling of mitochondrial biogenesis induced by endurance exercise in human skeletal muscle
    • Wang L, Mascher H, Psilander N, Blomstrand E, Sahlin K. Resistance exercise enhances the molecular signaling of mitochondrial biogenesis induced by endurance exercise in human skeletal muscle. J Appl Physiol. 2011;111:1335-1344.
    • (2011) J Appl Physiol , vol.111 , pp. 1335-1344
    • Wang, L.1    Mascher, H.2    Psilander, N.3    Blomstrand, E.4    Sahlin, K.5
  • 28
    • 84874118669 scopus 로고    scopus 로고
    • Molecular adaptations to concurrent training
    • de Souza EO, Tricoli V, Roschel H, et al. Molecular adaptations to concurrent training. Int J Sports Med. 2013;34:207-213.
    • (2013) Int J Sports Med , vol.34 , pp. 207-213
    • De Souza, E.O.1    Tricoli, V.2    Roschel, H.3
  • 29
    • 84868304039 scopus 로고    scopus 로고
    • Long-term physical exercise induces changes in sirtuin 1 pathway and oxidative parameters in adult rat tissues
    • Bayod S, Del Valle J, Lalanza JF, et al. Long-term physical exercise induces changes in sirtuin 1 pathway and oxidative parameters in adult rat tissues. Exp Gerontol. 2012;47:925-935.
    • (2012) Exp Gerontol , vol.47 , pp. 925-935
    • Bayod, S.1    Del Valle, J.2    Lalanza, J.F.3
  • 31
    • 63849228324 scopus 로고    scopus 로고
    • Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training
    • Alsted TJ, Nybo L, Schweiger M, et al. Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training. Am J Physiol Endocrinol Metab. 2009;296:E445-E453.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Alsted, T.J.1    Nybo, L.2    Schweiger, M.3
  • 32
    • 8844233479 scopus 로고    scopus 로고
    • Effect of exercise training on muscle glucose transporter 4 protein and intramuscular lipid content in elderly men with impaired glucose tolerance
    • Kim HJ, Lee JS, Kim CK. Effect of exercise training on muscle glucose transporter 4 protein and intramuscular lipid content in elderly men with impaired glucose tolerance. Eur J Appl Physiol. 2004;93: 353-358.
    • (2004) Eur J Appl Physiol , vol.93 , pp. 353-358
    • Kim, H.J.1    Lee, J.S.2    Kim, C.K.3
  • 33
    • 84873155308 scopus 로고    scopus 로고
    • Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5
    • Shepherd SO, Cocks M, Tipton KD, et al. Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5. J Physiol. 2013; 591:657-675.
    • (2013) J Physiol , vol.591 , pp. 657-675
    • Shepherd, S.O.1    Cocks, M.2    Tipton, K.D.3
  • 34
    • 38949161524 scopus 로고    scopus 로고
    • Determinants of intramyocellular triglyceride turnover: Implications for insulin sensitivity
    • Moro C, Bajpeyi S, Smith SR. Determinants of intramyocellular triglyceride turnover: implications for insulin sensitivity. Am J Physiol Endocrinol Metab. 2008;294:E203-E213.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Moro, C.1    Bajpeyi, S.2    Smith, S.R.3
  • 35
    • 72549084334 scopus 로고    scopus 로고
    • Relationship between plasma free fatty acid, intramyocellular triglycerides and long-chain acylcarnitines in resting humans
    • Kanaley JA, Shadid S, Sheehan MT, Guo Z, Jensen MD. Relationship between plasma free fatty acid, intramyocellular triglycerides and long-chain acylcarnitines in resting humans. J Physiol. 2009; 587:5939-5950.
    • (2009) J Physiol , vol.587 , pp. 5939-5950
    • Kanaley, J.A.1    Shadid, S.2    Sheehan, M.T.3    Guo, Z.4    Jensen, M.D.5
  • 36
    • 59149100574 scopus 로고    scopus 로고
    • Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates
    • Krintel C, Osmark P, Larsen MR, Resjo S, Logan DT, Holm C. Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates. PloS One. 2008;3:e3756.
    • (2008) PloS One , vol.3
    • Krintel, C.1    Osmark, P.2    Larsen, M.R.3    Resjo, S.4    Logan, D.T.5    Holm, C.6
  • 37
    • 84862330756 scopus 로고    scopus 로고
    • Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans
    • Bergman BC, Hunerdosse DM, Kerege A, Playdon MC, Perreault L. Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans. Diabetologia. 2012;55:1140-1150.
    • (2012) Diabetologia , vol.55 , pp. 1140-1150
    • Bergman, B.C.1    Hunerdosse, D.M.2    Kerege, A.3    Playdon, M.C.4    Perreault, L.5
  • 38
    • 33646128723 scopus 로고    scopus 로고
    • Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in chanarin-dorfman syndrome
    • Lass A, Zimmermann R, Haemmerle G, et al. Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman syndrome. Cell Metab. 2006; 3:309-319.
    • (2006) Cell Metab , vol.3 , pp. 309-319
    • Lass, A.1    Zimmermann, R.2    Haemmerle, G.3
  • 39
    • 33845517481 scopus 로고    scopus 로고
    • OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization
    • Wolins NE, Quaynor BK, Skinner JR, et al. OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization. Diabetes. 2006;55:3418-3428.
    • (2006) Diabetes , vol.55 , pp. 3418-3428
    • Wolins, N.E.1    Quaynor, B.K.2    Skinner, J.R.3
  • 40
    • 40849145708 scopus 로고    scopus 로고
    • Lipid droplets in lipogenesis and lipolysis
    • DucharmeNA,Bickel PE. Lipid droplets in lipogenesis and lipolysis. Endocrinology. 2008;149:942-949.
    • (2008) Endocrinology , vol.149 , pp. 942-949
    • Ducharme, N.A.1    Bickel, P.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.