Basic research and clinical applications of bisphosphonates in bone disease: What have we learned over the last 40 years?

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Xu, Xiao Long ^a   Gou, Wen Long ^a   Wang, Ai Yuan ^a   Wang, Yu ^a   Guo, Quan Yi ^a   Lu, Qiang ^a   Lu, Shi Bi ^a   Peng, Jiang ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Bisphosphonate; Osteoblast; Osteoclast; Osteoporosis; Pharmacokinetics

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CLODRONIC ACID; CONNEXIN 43; ETIDRONIC ACID; ETIDRONIC ACID TC 99M; FLUORODEOXYGLUCOSE F 18; GERANYLTRANSFERASE; IBANDRONIC ACID; MEVALONIC ACID; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RISEDRONIC ACID; ZOLEDRONIC ACID;

APOPTOSIS; ATYPICAL FEMORAL FRACTURE; BONE DISEASE; BONE FRAGILITY; BONE METASTASIS; BONE SCINTISCANNING; BONE TURNOVER; CELL PROTECTION; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG SAFETY; DRUG UPTAKE; DRUG WITHDRAWAL; DYSPEPSIA; ESOPHAGITIS; ESOPHAGUS CANCER; EYE INFLAMMATION; FEMUR FRACTURE; FOOD; FOOD DRUG INTERACTION; GASTRITIS; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL IRRITATION; GASTROINTESTINAL SYMPTOM; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HUMAN; HYPERPARATHYROIDISM; JAW OSTEONECROSIS; MYELOMA; NONHUMAN; OSTEOARTHRITIS; OSTEOBLAST; OSTEOCYTE; OSTEOPOROSIS; PATIENT COMPLIANCE; PERTHES DISEASE; REVIEW; STOMACH IRRITATION;

BONE DISEASES; DIPHOSPHONATES; HUMANS; TISSUE DISTRIBUTION;

EID: 84889786252     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-303     Document Type: Review

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