Total synthesis and biological evaluation of jerantinineE

Angewandte Chemie - International Edition

Volumn 52, Issue 50, 2013, Pages 13373-13376

  Frei, Reto ^a   Staedler, Davide ^a   Raja, Aruna ^b   Franke, Raimo ^b   Sasse, Florenz ^b   Gerber Lemaire, Sandrine ^a   Waser, Jérôme ^a  

^a EPFL   (Switzerland)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

alkaloids; cancer; indoles; natural products; total synthesis

Indexed keywords

BIOLOGICAL EVALUATION; CANCER; INDOLES; LUNG CANCER CELLS; NATURAL PRODUCTS; TOTAL SYNTHESIS;

ALKALOIDS; CELL CULTURE; CYTOTOXICITY; METABOLITES; NITROGEN COMPOUNDS;

SYNTHESIS (CHEMICAL);

ALKALOID; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; JERANTININE E; TUBULIN; VINCA ALKALOID;

ANIMAL; ARTICLE; ASPIDOSPERMA; CELL LINE; CELL MOTION; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; HUMAN; MCF 7 CELL LINE; METABOLISM; MOUSE; NATURAL PRODUCTS; NEOPLASM; POLYMERIZATION; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TOTAL SYNTHESIS;

ALKALOIDS; CANCER; INDOLES; NATURAL PRODUCTS; TOTAL SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ASPIDOSPERMA; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MCF-7 CELLS; MICE; MOLECULAR CONFORMATION; POLYMERIZATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN; VINCA ALKALOIDS;

EID: 84889681434     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201305533     Document Type: Article

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