Use of health information technology (HIT) to improve statin adherence and low-density lipoprotein cholesterol goal attainment in high-risk patients: Proceedings from a workshop

Journal of Clinical Lipidology

Volumn 7, Issue 6, 2013, Pages 573-609

  Cohen, Jerome D ^a   Aspry, Karen E ^b   Brown, Alan S ^c   Foody, Joanne M ^d   Furman, Roy ^e   Jacobson, Terry A ^f   Karalis, Dean G ^g   Kris Etherton, Penny M ^h   Laforge, Ralph ⁱ   O'Toole, Michael F ^c   Scott, Ronald D ^j   Underberg, James A ^k   Valuck, Thomas B ^l   Willard, Kaye Eileen ^m   Ziajka, Paul E ⁿ   Ito, Matthew K ^o  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BROWN UNIVERSITY   (United States)

^c ADVOCATE LUTHERAN GENERAL HOSPITAL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e Intelligent Medical Decisions Inc   (United States)

^f EMORY UNIVERSITY   (United States)

^g PENNSYLVANIA HOSPITAL   (United States)

^h PENNSYLVANIA STATE UNIVERSITY   (United States)

ⁱ Cardiometabolic Risk Management Consultants   (United States)

^j KAISER PERMANENTE   (United States)

^k NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l NATIONAL QUALITY FORUM   (United States)

^m Wheaton Franciscan Healthcare   (United States)

ⁿ Florida Lipid Associates   (United States)

^o OREGON STATE UNIVERSITY   (United States)

more..

Author keywords

Adherence; Electronic health record; Electronic prescribing; Health information technology; Low density lipoprotein cholesterol; Statin

Indexed keywords

ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

DECISION SUPPORT SYSTEM; ELECTRONIC PRESCRIBING; GOAL ATTAINMENT; HIGH RISK PATIENT; HUMAN; HYPERCHOLESTEROLEMIA; MEDICAL INFORMATICS; MEDICATION COMPLIANCE; PATIENT COMPLIANCE; PRESCRIPTION; PRIMARY PREVENTION; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; TOTAL QUALITY MANAGEMENT; TREATMENT REFUSAL; UNSPECIFIED SIDE EFFECT; WORKSHOP;

ADHERENCE; ELECTRONIC HEALTH RECORD; ELECTRONIC PRESCRIBING; HEALTH INFORMATION TECHNOLOGY; LOW-DENSITY LIPOPROTEIN CHOLESTEROL; STATIN;

CHOLESTEROL, LDL; CORONARY DISEASE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MEDICAL INFORMATICS; MEDICATION ADHERENCE; POINT-OF-CARE SYSTEMS; RISK FACTORS;

EID: 84889664945     PISSN: 19332874     EISSN: 18764789     Source Type: Journal    
DOI: 10.1016/j.jacl.2013.10.002     Document Type: Article

References (86)

1. A.S. Go, D. Mozaffarian, V.L. Roger American Heart Association Statistics Committee Executive summary: heart disease and stroke statistics-2013 update: a report from the American Heart Association Circulation 127 2013 143 152
2. A. Bitton, and T.A. Gaziano The Framingham Heart Study's impact on global risk assessment Prog Cardiovasc Dis 53 2010 63 78
3. D. Steinberg The Cholesterol Wars. The Skeptics vs. the Preponderance of Evidence 2007 Academic Press New York, NY
4. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III) JAMA 285 2001 2486 2497
5. S.M. Grundy, J.I. Cleeman, C.N. Merz National Heart, Lung, and Blood Institute; American College of Cardiology Foundation; American Heart Association Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines Circulation 110 2004 227 239
6. M.H. Davidson, K.C. Maki, and T.A. Pearson Results of the National Cholesterol Education (NCEP) Program Evaluation ProjecT Utilizing Novel E-Technology (NEPTUNE) II survey and implications for treatment under the recent NCEP Writing Group recommendations Am J Cardiol 96 2005 556 563
7. T.M. Maddox, and P.M. Ho Medication adherence and the patient with coronary artery disease: challenges for the practitioner Curr Opin Cardiol 24 2009 468 472
8. J.D. Cohen, E.A. Brinton, M.K. Ito, and T.A. Jacobson Understanding Statin Use in America and Gaps in Patient Education (USAGE): an internet-based survey of 10,138 current and former statin users J Clin Lipidol 6 2012 208 215
9. Oyekan E. The B-SMART medication adherence checklist. A tool to make it easier for physicians and providers to do the right thing when addressing America's other drug problem - medication non adherence. Available at: http://dmhc.ca.gov/library/reports/news/rci/oyekan.pdf. Accessed September 10, 2013.
10. National Committee for Quality Assurance. Focus on Obesity and on Medicare Plan Improvement: The State of Health Care Quality. 2012. Available at: http://www.ncqa.org/Portals/0/State%20of%20Health%20Care/2012/ SOHC%20Report%20Web.pdf. Accessed September 2, 2013.
11. New England Healthcare Institute. Thinking outside the pillbox: a system-wide approach to improving patient medication adherence for chronic disease. A NEHI Research Brief - August 2009. Available at: http://www.nehi.net/ publications/44/thinking-outside-the-pillbox-a-systemwide-approach-to-improving- patient-medication-adherence-for-chronic-disease. Accessed September 5, 2013.
12. U.S. Congress. American Recovery and Reinvestiment Act of 2009. Available at: http://www.healthit.gov/sites/default/files/hitech-act-excerpt-from-arra. pdf. Accessed September 2, 2013.
13. Chan M. Reducing cost-related medication nonadherence in patients with diabetes. Available at: http://dbt.consultantlive.com/diabetes-management/ content/article/1145628/1554670. Accessed September 28, 2013.
14. S.F. Derose, K. Green, and E. Marrett Automated outreach to increase primary adherence to cholesterol-lowering medications JAMA Intern Med 173 2013 38 43
15. R.W. Yeh, S. Sidney, M. Chandra, M. Sorel, J.V. Selby, and A.S. Go Population trends in the incidence and outcomes of acute myocardial infarction N Engl J Med 362 2010 2155 2165
16. I. Hetlevik, J. Holmen, and O. Kruger Implementing clinical guidelines in the treatment of hypertension in general practice. Evaluation of patient outcome related to implementation of a computer-based clinical decision support system Scand J Prim Health Care 17 1999 35 40
17. J.B. Meigs, E. Cagliero, and A. Dubey A controlled trial of web-based diabetes disease management: the MGH diabetes primary care improvement project Diabetes Care 26 2003 750 757
18. W.M. Tierney, J.M. Overhage, and M.D. Murray Effects of computerized guidelines for managing heart disease in primary care J Gen Intern Med 18 2003 967 976
19. P.S. Mehler, M.J. Krantz, and R.A. Lundgren Bridging the quality gap in diabetic hyperlipidemia: a practice-based intervention Am J Med 118 2005 1414
20. T.D. Sequist, T.K. Gandhi, and A.S. Karson A randomized trial of electronic clinical reminders to improve quality of care for diabetes and coronary artery disease J Am Med Inform Assoc 12 2005 431 437
21. W.T. Lester, R.W. Grant, G.O. Barnett, and H.C. Chueh Randomized controlled trial of an informatics-based intervention to increase statin prescription for secondary prevention of coronary disease J Gen Intern Med 21 2006 22 29
22. F.G. Cleveringa, K.J. Gorter, M. van den Donk, and G.E. Rutten Combined task delegation, computerized decision support, and feedback improve cardiovascular risk for type 2 diabetic patients: a cluster randomized trial in primary care Diabetes Care 31 2008 2273 2275
23. S.A. Smith, N.D. Shah, and S.C. Bryant Chronic care model and shared care in diabetes: randomized trial of an electronic decision support system Mayo Clin Proc 83 2008 747 757
24. J.T. van Wyk, M.A. van Wijk, M.C. Sturkenboom, M. Mosseveld, P.W. Moorman, and J. van der Lei Electronic alerts versus on-demand decision support to improve dyslipidemia treatment: a cluster randomized controlled trial Circulation 117 2008 371 378
25. A.G. Bertoni, D.E. Bonds, and H. Chen Impact of a multifaceted intervention on cholesterol management in primary care practices: guideline adherence for heart health randomized trial Arch Intern Med 169 2009 678 686
26. P.J. O'Connor, J.M. Sperl-Hillen, and P.E. Johnson Simulated physician learning intervention to improve safety and quality of diabetes care: a randomized trial Diabetes Care 32 2009 585 590
27. P.J. O'Connor, J.M. Sperl-Hillen, and W.A. Rush Impact of electronic health record clinical decision support on diabetes care: a randomized trial Ann Fam Med 9 2011 12 21
28. M. Verheijden, J.C. Bakx, and R. Akkermans Web-based targeted nutrition counselling and social support for patients at increased cardiovascular risk in general practice: randomized controlled trial J Med Internet Res 6 2004 e44
29. K. Harno, R. Kauppinen-Makelin, and J. Syrjalainen Managing diabetes care using an integrated regional e-health approach J Telemed Telecare 12 suppl 1 2006 13 15
30. S. Shea, R.S. Weinstock, and J. Starren A randomized trial comparing telemedicine case management with usual care in older, ethnically diverse, medically underserved patients with diabetes mellitus J Am Med Inform Assoc 13 2006 40 51
31. G.E. Bond, R. Burr, F.M. Wolf, M. Price, S.M. McCurry, and L. Teri The effects of a web-based intervention on the physical outcomes associated with diabetes among adults age 60 and older: a randomized trial Diabetes Technol Ther 9 2007 52 59
32. S.A. Grover, I. Lowensteyn, L. Joseph Cardiovascular Health Evaluation to Improve Compliance and Knowledge Among Uninformed Patients (CHECK-UP) Study Group Patient knowledge of coronary risk profile improves the effectiveness of dyslipidemia therapy: the CHECK-UP study: a randomized controlled trial Arch Intern Med 167 2007 2296 2303
33. R.W. Grant, J.S. Wald, and J.L. Schnipper Practice-linked online personal health records for type 2 diabetes mellitus: a randomized controlled trial Arch Intern Med 168 2008 1776 1782
34. R. Webster, S. Li, D.R. Sullivan, K. Jayne, S.Y. Su, and B. Neal Effects of internet-based tailored advice on the use of cholesterol-lowering interventions: a randomized controlled trial J Med Internet Res 12 2010 e42
35. S.L. Sheridan, L.B. Draeger, and M.P. Pignone A randomized trial of an intervention to improve use and adherence to effective coronary heart disease prevention strategies BMC Health Serv Res 11 2011 331
36. R.E. Glasgow, D. Kurz, and D. King Twelve-month outcomes of an Internet-based diabetes self-management support program Patient Educ Couns 87 2012 81 92
37. J.W. Vernooij, H.A. Kaasjager, and Y. van der Graaf Internet based vascular risk factor management for patients with clinically manifest vascular disease: randomised controlled trial BMJ 344 2012 e3750
38. J.S. Benner, L. Erhardt, M. Flammer REACH OUT Investigators A novel programme to evaluate and communicate 10-year risk of CHD reduces predicted risk and improves patients' modifiable risk factor profile Int J Clin Pract 62 2008 1484 1498
39. A. Holbrook, L. Thabane, K. Keshavjee COMPETE II Investigators Individualized electronic decision support and reminders to improve diabetes care in the community: COMPETE II randomized trial CMAJ 181 2009 37 44
40. A. Holbrook, E. Pullenayegum, and L. Thabane Shared electronic vascular risk decision support in primary care: Computerization of Medical Practices for the Enhancement of Therapeutic Effectiveness (COMPETE III) randomized trial Arch Intern Med 171 2011 1736 1744
41. C.B. Eaton, D.R. Parker, and J. Borkan Translating cholesterol guidelines into primary care practice: a multimodal cluster randomized trial Ann Fam Med 9 2011 528 537
42. K.A. Peterson, D.M. Radosevich, and P.J. O'Connor Improving Diabetes Care in Practice: findings from the TRANSLATE trial Diabetes Care 31 2008 2238 2243
43. H. Gilutz, L. Novack, and P. Shvartzman Computerized community cholesterol control (4C): meeting the challenge of secondary prevention Isr Med Assoc J 11 2009 23 29
44. S.R. Simon, C.M. Trinacty, and S.B. Soumerai Improving diabetes care among patients overdue for recommended testing: a randomized controlled trial of automated telephone outreach Diabetes Care 33 2010 1452 1453
45. G.A. Pape, J.S. Hunt, and K.L. Butler Team-based care approach to cholesterol management in diabetes mellitus: two-year cluster randomized controlled trial Arch Intern Med 171 2011 1480 1486
46. J.V. Selby, J.A. Schmittdiel, and B. Fireman Improving treatment intensification to reduce cardiovascular disease risk: a cluster randomized trial BMC Health Serv Res 12 2012 183
47. M.J. Kooy, B.L. van Wijk, E.R. Heerdink, A. de Boer, and M.L. Bouvy Does the use of an electronic reminder device with or without counseling improve adherence to lipid-lowering treatment? The results of a randomized controlled trial Front Pharmacol 4 2013 69
48. S.D. Persell, D.M. Lloyd-Jones, E.M. Friesema, A.J. Cooper, and D.W. Baker Electronic health record-based patient identification and individualized mailed outreach for primary cardiovascular disease prevention: a cluster randomized trial J Gen Intern Med 28 2013 554 560
49. J.W. Kinn, M.F. O'Toole, S.M. Rowley, J.C. Marek, V.J. Bufalino, and A.S. Brown Effectiveness of the electronic medical record in cholesterol management in patients with coronary artery disease (Virtual Lipid Clinic) Am J Cardiol 88 2001 163 165 A5
50. J.W. Kinn, and A.S. Brown Cardiovascular risk management in clinical practice: the Midwest Heart Specialists experience Am J Cardiol 89 2002 23C 29C [discussion 30C]
51. B.J. Ansell, G.C. Fonarow, K.C. Maki, M.R. Dicklin, M. Bell, M.H. Davidson Neptune II Steering Committee Reduced treatment success in lipid management among women with coronary heart disease or risk equivalents: results of a national survey Am Heart J 152 2006 976 981
52. World Health Organization. Adherence to long-term therapies: evidence for action. Available at: http://apps.who.int/medicinedocs/pdf/s4883e/s4883e.pdf. Accessed September 8, 2013.
53. International Society for Pharmacoeconomics & Outcomes Research. Medication compliance and persistence special interest group: standardizing definition of terms. Available at: http://www.ispor.org/sigs/MCP- accomplishments.asp#/definition. Accessed September 8, 2013.
54. J. Avorn, J. Monette, and A. Lacour Persistence of use of lipid-lowering medications: a cross-national study JAMA 279 1998 1458 1462
55. J.S. Benner, R.J. Glynn, H. Mogun, P.J. Neumann, M.C. Weinstein, and J. Avorn Long-term persistence in use of statin therapy in elderly patients JAMA 288 2002 455 461
56. C.A. Jackevicius, M. Mamdani, and J.V. Tu Adherence with statin therapy in elderly patients with and without acute coronary syndromes JAMA 288 2002 462 467
57. L.A. Simons, G. Levis, and J. Simons Apparent discontinuation rates in patients prescribed lipid-lowering drugs Med J Aust 164 1996 208 211
58. J. Larsen, M. Andersen, J. Kragstrup, and L.F. Gram High persistence of statin use in a Danish population: compliance study 1993-1998 Br J Clin Pharmacol 53 2002 375 378
59. J.P. Frolkis, G.L. Pearce, V. Nambi, S. Minor, and D.L. Sprecher Statins do not meet expectations for lowering low-density lipoprotein cholesterol levels when used in clinical practice Am J Med 113 2002 625 629
60. E.S. Parris, D.B. Lawrence, L.A. Mohn, and L.B. Long Adherence to statin therapy and LDL cholesterol goal attainment by patients with diabetes and dyslipidemia Diabetes Care 28 2005 595 599
61. M.C. Sokol, K.A. McGuigan, R.R. Verbrugge, and R.S. Epstein Impact of medication adherence on hospitalization risk and healthcare cost Med Care 43 2005 521 530
62. D.P. Goldman, G.F. Joyce, and P. Karaca-Mandic Varying pharmacy benefits with clinical status: the case of cholesterol-lowering therapy Am J Manag Care 12 2006 21 28
63. J. Shepherd, S.M. Cobbe, and I. Ford Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group N Engl J Med 333 1995 1301 1307
64. L. Wei, J. Wang, P. Thompson, S. Wong, A.D. Struthers, and T.M. MacDonald Adherence to statin treatment and readmission of patients after myocardial infarction: a six year follow up study Heart 88 2002 229 233
65. C. Heeschen, C.W. Hamm, U. Laufs, S. Snapinn, M. Bohm, H.D. White Platelet Receptor Inhibition in Ischemic Syndrome Management (PRISM) Investigators Withdrawal of statins increases event rates in patients with acute coronary syndromes Circulation 105 2002 1446 1452
66. M. Thomas, and J. Mann Increased thrombotic vascular events after change of statin Lancet 352 1998 1830 1831
67. J.S. McCombs, M.B. Nichol, C.M. Newman, and D.A. Sclar The costs of interrupting antihypertensive drug therapy in a Medicaid population Med Care 32 1994 214 226
68. J.S. Schultz, J.C. O'Donnell, K.L. McDonough, R. Sasane, and J. Meyer Determinants of compliance with statin therapy and low-density lipoprotein cholesterol goal attainment in a managed care population Am J Manag Care 11 2005 306 312
69. H.B. Bosworth, T. Dudley, and M.K. Olsen Racial differences in blood pressure control: potential explanatory factors Am J Med 119 70 2006 e9 15
70. Safran DG, Neuman T, Schoen C, Kitchman MS, et al. Prescription drug coverage and seniors: findings from a 2003 national survey. Health Affairs Web Exclusive. Available at: http://www.commonwealthfund.org/Publications/In-the- Literature/2005/Apr/Prescription-Drug-Coverage-and-SeniorsFindings-From-a-2003- National-Survey.aspx. Accessed September 8, 2013.
71. M. Monane, R.L. Bohn, J.H. Gurwitz, R.J. Glynn, R. Levin, and J. Avorn The effects of initial drug choice and comorbidity on antihypertensive therapy compliance: results from a population-based study in the elderly Am J Hypertens 10 1997 697 704
72. J.W. Cheng, M.M. Kalis, and S. Feifer Patient-reported adherence to guidelines of the Sixth Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure Pharmacotherapy 21 2001 828 841
73. P. Ley, P.W. Bradshaw, D. Eaves, and C.M. Walker A method for increasing patients' recall of information presented by doctors Psychol Med 3 1973 217 220
74. J.M. Mazzullo III, L. Lasagna, and P.F. Griner Variations in interpretation of prescription instructions. The need for improved prescribing habits JAMA 227 1974 929 931
75. P. Ruiz, and P.P. Ruiz Treatment compliance among Hispanics J Operational Psychiatry 14 1983 112 114
76. R.H. Chapman, J.S. Benner, and A.A. Petrilla Predictors of adherence with antihypertensive and lipid-lowering therapy Arch Intern Med 165 2005 1147 1152
77. N.K. Choudhry, J. Avorn, R.J. Glynn Post-Myocardial Infarction Free Rx Event and Economic Evaluation (MI FREEE) Trial Full coverage for preventive medications after myocardial infarction N Engl J Med 365 2011 2088 2097
78. Merck & Co Inc. The Adherence Estimator. Available at: https://www.merckengage.com/hcp/rx-for-health/adherence-estimator.aspx. Accessed September 21, 2013.
79. M.A. Fischer, C. Vogeli, M. Stedman, T. Ferris, M.A. Brookhart, and J.S. Weissman Effect of electronic prescribing with formulary decision support on medication use and cost Arch Intern Med 168 2008 2433 2439
80. Surescripts. The National Progress Report on E-Prescribing and Safe Rx Rankings. 2012. Available at: http://www.surescripts.com/downloads/npr/ National%20Progress%20Report%20on%20E%20Prescribing%20Year%202012.pdf. Accessed September 8, 2013.
81. M. Vergeer, S.J. Korporaal, and R. Franssen Genetic variant of the scavenger receptor BI in humans N Engl J Med 364 2011 136 145
82. K.C. Michelis, B. Hassouna, M. Owlia, L. Kelahan, H.A. Young, and B.G. Choi Effect of electronic prescription on attainment of cholesterol goals Clin Cardiol 34 2011 254 260
83. R.L. McClelland, K. Nasir, M. Budoff, R.S. Blumenthal, and R.A. Kronmal Arterial age as a function of coronary artery calcium (from the Multi-Ethnic Study of Atherosclerosis [MESA]) Am J Cardiol 103 2009 59 63
84. G.J. Langley, R. Moen, K.M. Nolan, T.W. Nolan, C.L. Norman, and L.P. Provost The Improvement Guide: A Practical Approach to Enhancing Organizational Performance 2nd ed. 2009 Jossey-Bass Publishers San Francisco, CA
85. Office of National Coordinator for Health Information Technology. Update on the adoption of health information technology and related efforts to facilitate electronic use and exchange of health information. A report to Congress 06/13. Available at: http://www.healthit.gov/sites/default/files/rtc- adoption-of-healthit-and-relatedefforts.pdf. Accessed September 21, 2013.
86. Dixon DL, Bolick JP, Godishala LM, et al. Clinician's Toolkit: A Guide to Medication and Lifestyle Adherence. National Lipid Association. Available at: http://www.lipid.org/practicetools/tools/adherence. Accessed October 28, 2013.