메뉴 건너뛰기




Volumn 73, Issue 1, 2014, Pages 298-305

Lysophosphatidic acid receptor inhibition as a new multipronged treatment for rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRHEUMATIC AGENT; COLONY STIMULATING FACTOR 1; KI 16425; LYSOPHOSPHATIDIC ACID RECEPTOR; OSTEOCLAST DIFFERENTIATION FACTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84889644214     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2012-202832     Document Type: Article
Times cited : (47)

References (45)
  • 1
    • 84855172814 scopus 로고    scopus 로고
    • The pathogenesis of rheumatoid arthritis
    • McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med 2011;365:2205-19.
    • (2011) N Engl J Med , vol.365 , pp. 2205-2219
    • McInnes, I.B.1    Schett, G.2
  • 2
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • DOI 10.1038/nature01661
    • Firestein GS. Evolving concepts of rheumatoid arthritis. Nature 2003;423:356-61. (Pubitemid 40852711)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 356-361
    • Firestein, G.S.1
  • 4
    • 73249125200 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes. Key effector cells in rheumatoid arthritis
    • Bartok B, Firestein GS. Fibroblast-like synoviocytes. Key effector cells in rheumatoid arthritis. Immunol Rev 2010;233:233-55.
    • (2010) Immunol Rev , vol.233 , pp. 233-255
    • Bartok, B.1    Firestein, G.S.2
  • 5
    • 1542267920 scopus 로고    scopus 로고
    • Radiological Progression in Established Rheumatoid Arthritis
    • Scott DL. Radiological progression in established rheumatoid arthritis. J Rheumatol Suppl 2004;69:55-65. (Pubitemid 38327494)
    • (2004) Journal of Rheumatology , vol.31 , Issue.SUPPL. 69 , pp. 55-65
    • Scott, D.L.1
  • 6
    • 0034930640 scopus 로고    scopus 로고
    • Osteoprotegerin and receptor activator of nuclear factor kappa B ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint
    • Haynes DR, Crotti TN, Loric M, et al. Osteoprotegerin and receptor activator of nuclear factor kappa B ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint. Rheumatology 2001;40:623-30.
    • (2001) Rheumatology , vol.40 , pp. 623-630
    • Haynes, D.R.1    Crotti, T.N.2    Loric, M.3
  • 7
    • 73249137735 scopus 로고    scopus 로고
    • Bone remodelling in rheumatic disease: A question of balance
    • Walsh NC, Gravallese EM. Bone remodelling in rheumatic disease: a question of balance. Immunol Rev 2010;233:301-12.
    • (2010) Immunol Rev , vol.233 , pp. 301-312
    • Walsh, N.C.1    Gravallese, E.M.2
  • 8
    • 84865801449 scopus 로고    scopus 로고
    • Pathways for bone loss in inflammatory disease
    • Braun T, Schett G. Pathways for bone loss in inflammatory disease. Curr Osteoporos Rep 2012;10:101-8.
    • (2012) Curr Osteoporos Rep , vol.10 , pp. 101-108
    • Braun, T.1    Schett, G.2
  • 9
    • 72749102524 scopus 로고    scopus 로고
    • Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis
    • Walsh NC, Reinwald S, Manning CA, et al. Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis. J Bone Miner Res 2009;24:1572-85.
    • (2009) J Bone Miner Res , vol.24 , pp. 1572-1585
    • Walsh, N.C.1    Reinwald, S.2    Manning, C.A.3
  • 10
    • 33845482745 scopus 로고    scopus 로고
    • A systematic review of the effectiveness of adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis in adults and an economic evaluation of their cost-effectiveness
    • xi-xiii 1-229
    • Chen YF, Jobanputra P, Barton P, et al. A systematic review of the effectiveness of adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis in adults and an economic evaluation of their cost-effectiveness. Health Technol Assess 2006;10:iii-iv, xi-xiii, 1-229.
    • (2006) Health Technol Assess , vol.10
    • Chen, Y.F.1    Jobanputra, P.2    Barton, P.3
  • 11
    • 54349087856 scopus 로고    scopus 로고
    • When patients with rheumatoid arthritis fail tumour necrosis factor inhibitors: What is the next step?
    • Smolen JS, Weinblatt ME. When patients with rheumatoid arthritis fail tumour necrosis factor inhibitors: what is the next step? Ann Rheum Dis 2008;67:1497-8.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1497-1498
    • Smolen, J.S.1    Weinblatt, M.E.2
  • 12
    • 84859517687 scopus 로고    scopus 로고
    • Remission and radiographic outcome in rheumatoid arthrtis: Application of the 2011 ACR/EULAR remission criteria in an observational cohort
    • Lillegraven S, Prince FH, Shadick NA, et al. Remission and radiographic outcome in rheumatoid arthrtis: application of the 2011 ACR/EULAR remission criteria in an observational cohort. Ann Rheum Dis 2012;71:681-6.
    • (2012) Ann Rheum Dis , vol.71 , pp. 681-686
    • Lillegraven, S.1    Prince, F.H.2    Shadick, N.A.3
  • 13
    • 84855355437 scopus 로고    scopus 로고
    • The association of treatment response and joint damage with ACPA-status in recent-onset RA: A subanalysis of the 8-year follow-up of the BeSt study
    • Van den Broek M, Dirven L, Klarenbeek NB, et al. The association of treatment response and joint damage with ACPA-status in recent-onset RA: a subanalysis of the 8-year follow-up of the BeSt study. Ann Rheum Dis 2012;71:245-8.
    • (2012) Ann Rheum Dis , vol.71 , pp. 245-248
    • Van Den Broek, M.1    Dirven, L.2    Klarenbeek, N.B.3
  • 14
    • 84855342821 scopus 로고    scopus 로고
    • In early rheumatoid arthritis, patients with a good initial response to methotrexate have excellent 2-year clinical outcomes, but radiological progression is not fully prevented: Data from the methotrexate responders population in the SWEFOT trial
    • Rezaei H, Saevarsdottir S, Forslind K, et al. In early rheumatoid arthritis, patients with a good initial response to methotrexate have excellent 2-year clinical outcomes, but radiological progression is not fully prevented: data from the methotrexate responders population in the SWEFOT trial. Ann Rheum Dis 2012;71:186-91.
    • (2012) Ann Rheum Dis , vol.71 , pp. 186-191
    • Rezaei, H.1    Saevarsdottir, S.2    Forslind, K.3
  • 15
    • 34247589636 scopus 로고    scopus 로고
    • Cells of the synovium in rheumatoid arthritis. Osteoclasts
    • Schett G. Cells of the synovium in rheumatoid arthritis. Osteoclasts. Arthritis Res Ther 2007;9:203.
    • (2007) Arthritis Res Ther , vol.9 , pp. 203
    • Schett, G.1
  • 16
    • 77955351696 scopus 로고    scopus 로고
    • Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis
    • Cejka D, Hayer S, Niederreiter B, et al. Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis. Arthritis Rheum 2010;62:2294-302.
    • (2010) Arthritis Rheum , vol.62 , pp. 2294-2302
    • Cejka, D.1    Hayer, S.2    Niederreiter, B.3
  • 18
    • 34247534260 scopus 로고    scopus 로고
    • Regulation and biological activities of the autotaxin-LPA axis
    • DOI 10.1016/j.plipres.2007.02.001, PII S0163782707000045
    • Van Meeteren LA, Moolenaar WH. Regulation and biological activities of the autotoxin-LPA axis. P Lipid Res 2007;46:145-60. (Pubitemid 46654231)
    • (2007) Progress in Lipid Research , vol.46 , Issue.2 , pp. 145-160
    • Van Meeteren, L.A.1    Moolenaar, W.H.2
  • 19
    • 0038152846 scopus 로고    scopus 로고
    • 9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family
    • DOI 10.1074/jbc.M302648200
    • Noguchi K, Ishii S, Shimizu T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from de Edg family. J Biol Chem 2006;278:25600-6. (Pubitemid 36835313)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.28 , pp. 25600-25606
    • Noguchi, K.1    Ishii, S.2    Shimizu, T.3
  • 24
    • 38549128932 scopus 로고    scopus 로고
    • Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: Implications for rheumatoid arthritis?
    • Zhao C, Fernandes MJ, Prestwich GD, et al. Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: Implications for rheumatoid arthritis? Mol Pharmacol 2007;73:587-600.
    • (2007) Mol Pharmacol , vol.73 , pp. 587-600
    • Zhao, C.1    Fernandes, M.J.2    Prestwich, G.D.3
  • 25
    • 58149290244 scopus 로고    scopus 로고
    • Stimulatory role of lysophosphatidic acid in cyclooxygenase-2 induction by synovial fluid of patients with rheumatoid arthritis in fibroblast-like synovial cells
    • Nochi H, Tomura H, Tobo M, et al. Stimulatory role of lysophosphatidic acid in cyclooxygenase-2 induction by synovial fluid of patients with rheumatoid arthritis in fibroblast-like synovial cells. J Immunol 2008;181:5111-19.
    • (2008) J Immunol , vol.181 , pp. 5111-5119
    • Nochi, H.1    Tomura, H.2    Tobo, M.3
  • 26
    • 84864425616 scopus 로고    scopus 로고
    • Lysophosphatidic acid receptor 1 suppression sensitizes rheumatoid fibroblast-like synoviocytes to TNF-induced apoptosis
    • Orosa B, González A, Mera A, et al. Lysophosphatidic acid receptor 1 suppression sensitizes rheumatoid fibroblast-like synoviocytes to TNF-induced apoptosis. Arthritis Rheum 2012;64:2460-70.
    • (2012) Arthritis Rheum , vol.64 , pp. 2460-2470
    • Orosa, B.1    González, A.2    Mera, A.3
  • 28
    • 62649089148 scopus 로고    scopus 로고
    • Evidence for lysophosphatidic acid 1 receptor signaling in the early phase of neuropatic pain mechanisms in experiments using Ki16425, a lysophosphatidic acid 1 receptor antagonist
    • Ma L, Matsumoto M, Xie W, et al. Evidence for lysophosphatidic acid 1 receptor signaling in the early phase of neuropatic pain mechanisms in experiments using Ki16425, a lysophosphatidic acid 1 receptor antagonist. J Neurochem 2009;109:603-10.
    • (2009) J Neurochem , vol.109 , pp. 603-610
    • Ma, L.1    Matsumoto, M.2    Xie, W.3
  • 29
    • 77954321169 scopus 로고    scopus 로고
    • A novel, orally active LPA1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model
    • Swaney JS, Chapman C, Correa LD, et al. A novel, orally active LPA1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model. J Pharmacol 2010;160:1699-713.
    • (2010) J Pharmacol , vol.160 , pp. 1699-1713
    • Swaney, J.S.1    Chapman, C.2    Correa, L.D.3
  • 30
    • 79955559412 scopus 로고    scopus 로고
    • Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma
    • Castelino FV, Seiders J, Bain G, et al. Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma. Arthritis Rheum 2011;63:1405-15.
    • (2011) Arthritis Rheum , vol.63 , pp. 1405-1415
    • Castelino, F.V.1    Seiders, J.2    Bain, G.3
  • 31
    • 78650612276 scopus 로고    scopus 로고
    • Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model
    • García S, Forteza J, López-Otin C, et al. Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model. Arthritis Res Ther 2010;12:R224.
    • (2010) Arthritis Res Ther , vol.12
    • García, S.1    Forteza, J.2    López-Otin, C.3
  • 33
    • 77954235258 scopus 로고    scopus 로고
    • Deficiency of CXCR2, but no other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model
    • Jacobs JP, Ortiz-Lopez A, Campbell JJ, et al. Deficiency of CXCR2, but no other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model. Arthritis Rheum 2010;62:1921-32.
    • (2010) Arthritis Rheum , vol.62 , pp. 1921-1932
    • Jacobs, J.P.1    Ortiz-Lopez, A.2    Campbell, J.J.3
  • 34
    • 43949108882 scopus 로고    scopus 로고
    • Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis
    • DOI 10.1002/art.23453
    • Chen M, Bilard E, Nigrovic PA, et al. Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis. Arthritis Rheum 2008;58:1354-65. (Pubitemid 351705925)
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.5 , pp. 1354-1365
    • Chen, M.1    Boilard, E.2    Nigrovic, P.A.3    Clark, P.4    Xu, D.5    FitzGerald, G.A.6    Audoly, L.P.7    Lee, D.M.8
  • 36
    • 84860501566 scopus 로고    scopus 로고
    • Osteoprotection by semaphorin 3A
    • Hayashi M, Nakashima T, Taniguchi M, et al. Osteoprotection by semaphorin 3A. Nature 2012;485:64-74.
    • (2012) Nature , vol.485 , pp. 64-74
    • Hayashi, M.1    Nakashima, T.2    Taniguchi, M.3
  • 37
    • 77955502352 scopus 로고    scopus 로고
    • Lysophosphatidic Acid Signals through Multiple Receptors in Osteoclasts to Elevate Cytosolic Calcium Concentration, Evoke Retraction, and Promote Cell Survival
    • Lapierre DM, Tanabe N, Pereverzev A, et al. Lysophosphatidic Acid Signals through Multiple Receptors in Osteoclasts to Elevate Cytosolic Calcium Concentration, Evoke Retraction, and Promote Cell Survival. J Biol Chem 2010;285:25792-801.
    • (2010) J Biol Chem , vol.285 , pp. 25792-25801
    • Lapierre, D.M.1    Tanabe, N.2    Pereverzev, A.3
  • 38
    • 77954338009 scopus 로고    scopus 로고
    • Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts
    • David M, Wannecq E, Descotes F, et al. Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts. PLoS One 2010;5:e9741.
    • (2010) PLoS One , vol.5
    • David, M.1    Wannecq, E.2    Descotes, F.3
  • 41
    • 79960587374 scopus 로고    scopus 로고
    • Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass
    • Gennero I, Laurencin-Dalicieux S, Conte-Auriol F, et al. Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass. Bone 2011;49:395-403.
    • (2011) Bone , vol.49 , pp. 395-403
    • Gennero, I.1    Laurencin-Dalicieux, S.2    Conte-Auriol, F.3
  • 42
    • 0034700050 scopus 로고    scopus 로고
    • Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behaviour
    • Contos JJA, Fukushima N, Weiner JA, et al. Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behaviour. Proc Natl Acad Sci USA 2000;97:13384-89.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13384-13389
    • Contos, J.J.A.1    Fukushima, N.2    Weiner, J.A.3
  • 43
    • 0035865386 scopus 로고    scopus 로고
    • Lysophosphatidic acid receptor-selective effects on Jurkat T cell migration through a matrigel model basement membrane
    • Zheng Y, Kong Y, Goetzl EJ. Lysophosphatidic acid receptor-selective effects on Jurkat T cell migration through a Matrigel model basement membrane. J Immunol 2001;166:2317-22. (Pubitemid 32173464)
    • (2001) Journal of Immunology , vol.166 , Issue.4 , pp. 2317-2322
    • Zheng, Y.1    Kong, Y.2    Goetzl, E.J.3
  • 44
    • 0032527809 scopus 로고    scopus 로고
    • Invasion of T-lymphoma cells: Cooperation between Rho family GTPases and lysophospholipid receptor signaling
    • DOI 10.1093/emboj/17.14.4066
    • Stam JC, Micchiels F, van der Kammen RA, et al. Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling. EMBO J 1998;17:4066-74 . (Pubitemid 28333990)
    • (1998) EMBO Journal , vol.17 , Issue.14 , pp. 4066-4074
    • Stam, J.C.1    Michiels, F.2    Van Der Kammen, R.A.3    Moolenaar, W.H.4    Collard, J.G.5
  • 45
    • 40949164579 scopus 로고    scopus 로고
    • Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs
    • DOI 10.1038/ni1573, PII NI1573
    • Kanda H, Newton R, Klein R, et al. Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs. Nature Immunol 2008;9:415-23. (Pubitemid 351405111)
    • (2008) Nature Immunology , vol.9 , Issue.4 , pp. 415-423
    • Kanda, H.1    Newton, R.2    Klein, R.3    Morita, Y.4    Gunn, M.D.5    Rosen, S.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.