Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritis joint

Rheumatology

Volumn 40, Issue 6, 2001, Pages 623-630

  Haynes, D R ^a   Crotti, T N ^a   Loric, M ^a   Bain, G I ^a   Atkins, G J ^a   Findlay, D M ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Bone; Cytokines; Joint damage; Osteoclasts; Osteoprotegerin; Rheumatoid arthritis

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; BIOLOGICAL MARKER; CALCITONIN RECEPTOR; COLONY STIMULATING FACTOR 1; LIGAND; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECOMBINANT OSTEOPROTEGERIN; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BONE EROSION; CELL ACTIVITY; CELL CULTURE; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; EXTRACTION; FEMALE; GENETIC CODE; HUMAN; JOINT; MALE; OSTEOCLAST; OSTEOLYSIS; PANNUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIUM;

EID: 0034930640     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/40.6.623     Document Type: Article

References (24)

1. Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis
2. Osteoclastic activation is the principal mechanism leading to secondary osteoporosis in rheumatoid arthritis
3. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
4. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
5. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
6. Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
7. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption
8. Human osteoclast formation and bone resorption by monocytes and synovial macrophages in rheumatoid arthritis
9. Osteoclastogenesis in iliac bone marrow of patients with rheumatoid arthritis
10. Activated T lymphocytes support osteoclast formation in vitro
11. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
12. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
13. Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis
14. Regulation of bone cells by particle-activated mononuclear phagocytes
15. Bidirectional signaling between stromal and hemopoietic cells regulates interleukin-1 expression during human osteoclast formation
16. Coordinated cytokine expression by stromal and hematopoietic cells during human osteoclast formation
17. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
18. TRANCE is a TNF family member that regulates dendritic cell and osteoclast function
19. Expression of osteoclast differentiation factor at sites of bone erosion in collagen-induced arthritis
20. Interleukin-1 beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells
21. Prostaglandin E2 cooperates with TRANCE in osteoclast induction from hemopoietic precursors: Synergistic activation of differentiation, cell spreading and fusion
22. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
23. Gene expression of monocyte chemoattractant protein-1 in giant cell tumors of bone osteoclastoma: Possible involvement in CD68 + macrophage-like cell migration
24. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression