Spectroscopic elucidation of the inhibitory mechanism of Cys 2His2 zinc finger transcription factors by cobalt(III) schiff base complexes

Chemistry - A European Journal

Volumn 19, Issue 50, 2013, Pages 17043-17053

  Heffern, Marie C ^a   Kurutz, Josh W ^a   Meade, Thomas J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

cobalt; Schiff bases; spectroscopy; transcription factors; zinc fingers

Indexed keywords

COBALT COMPLEXES (III); RANDOM-COIL CONFORMATIONS; SCHIFF BASIS; SPECTROSCOPIC ELUCIDATION; SPECTROSCOPIC INVESTIGATIONS; TRANSITION-METAL COMPLEX; ZINC FINGER; ZINC FINGER TRANSCRIPTION FACTOR;

AMINO ACIDS; COBALT; COMPLEXATION; CONFORMATIONS; DISSOCIATION; FUNCTIONAL GROUPS; GENES; HYDROGEN BONDS; LIGANDS; METAL COMPLEXES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES; SPECTROSCOPIC ANALYSIS; SPECTROSCOPY; TRANSCRIPTION FACTORS; ZINC;

COBALT COMPOUNDS;

COBALT; COORDINATION COMPOUND; CYSTINE; HISTIDINE; LIGAND; METALLOPROTEIN; OLIGOPEPTIDE; SCHIFF BASE; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ARTICLE; BINDING SITE; CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN SECONDARY STRUCTURE; SPECTROSCOPY;

COBALT; SCHIFF BASES; SPECTROSCOPY; TRANSCRIPTION FACTORS; ZINC FINGERS;

BINDING SITES; COBALT; COORDINATION COMPLEXES; CYSTINE; HISTIDINE; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; METALLOPROTEINS; OLIGOPEPTIDES; PROTEIN STRUCTURE, SECONDARY; SCHIFF BASES; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 84889595075     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201301659     Document Type: Article

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