Chromosome inversions in lymphocytes of prostate cancer patients treated with X-rays and carbon ions

Radiotherapy and Oncology

Volumn 109, Issue 2, 2013, Pages 256-261

  Pignalosa, Diana ^a   Lee, Ryonfa ^a,b   Hartel, Carola ^a   Sommer, Sylvester ^c   Nikoghosyan, Anna ^d   Debus, Jürgen ^d   Ritter, Sylvia ^a   Durante, Marco ^a,e  

^a GSI HELMHOLTZZENTRUM FÜR SCHWERIONENFORSCHUNG GMBH   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c INSTITUTE OF NUCLEAR CHEMISTRY AND TECHNOLOGY   (Poland)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^e DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Chromosome aberrations; Heavy ions; mBAND; Radiotherapy; Second cancer

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CANCER PATIENT; CHROMOSOME 2; CHROMOSOME BANDING PATTERN; CHROMOSOME BREAKAGE; CHROMOSOME INVERSION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOGENETICS; HUMAN; HUMAN CELL; IN VITRO STUDY; INTENSITY MODULATED RADIATION THERAPY; ION THERAPY; IRRADIATION; MALE; MULTICOLOUR BANDING TECHNIQUE; OUTCOME ASSESSMENT; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE FRACTIONATION; RADIATION HAZARD; SECOND CANCER; X RAY;

CHROMOSOME ABERRATIONS; HEAVY IONS; MBAND; RADIOTHERAPY; SECOND CANCER;

CHROMOSOME INVERSION; HEAVY ION RADIOTHERAPY; HUMANS; LYMPHOCYTES; MALE; PROSTATIC NEOPLASMS; X-RAY THERAPY;

EID: 84889571357     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.09.021     Document Type: Article

References (42)

1. M. Durante, and J.S. Loeffler Charged particles in radiation oncology Nat Rev Clin Oncol 7 2010 37 43
2. D. Schardt, T. Elsässer, and D. Schulz-Ertner Heavy-ion tumor therapy: physical and radiobiological benefits Rev Mod Phys 82 2010 383 425
3. J.S. Loeffler, and M. Durante Charged particle therapy-optimization, challenges and future directions Nat Rev Clin Oncol 10 2013 411 424
4. D. Pignalosa, and M. Durante Overcoming resistance of cancer stem cells Lancet Oncol 13 2012 e187 e188
5. A. Kronenberg, S. Gauny, and K. Criddle Heavy ion mutagenesis: linear energy transfer effects and genetic linkage Radiat Environ Biophys 34 1995 73 78
6. -/+ Mice Plos One 8 2013 e59295
7. W.D. Newhauser, and M. Durante Assessing the risk of second malignancies after modern radiotherapy Nat Rev Cancer 11 2011 438 448
8. M. Durante Biomarkers of space radiation risk Radiat Res 164 2005 467 473
9. S. Bonassi, H. Norppa, and M. Ceppi Chromosomal aberration frequency in lymphocytes predicts the risk of cancer: results from a pooled cohort study of 22,358 subjects in 11 countries Carcinogenesis 29 2008 1178 1183
10. F. Mitelman, B. Johansson, and F. Mertens The impact of translocations and gene fusions on cancer causation Nat Rev Cancer 7 2007 233 245
11. M. Durante, S. Yamada, and K. Ando X-rays vs. carbon-ion tumor therapy: cytogenetic damage in lymphocytes Int J Radiat Oncol Biol Phys 47 2000 793 798
12. R. Lee, S. Yamada, and N. Yamamoto Chromosomal aberrations in lymphocytes of lung cancer patients treated with carbon ions J Radiat Res (Tokyo) 45 2004 195 199
13. C. Hartel, A. Nikoghosyan, and M. Durante Chromosomal aberrations in peripheral blood lymphocytes of prostate cancer patients treated with IMRT and carbon ions Radiother Oncol 95 2010 73 78
14. D.J. Brenner, and R.K. Sachs Chromosomal "fingerprints" of prior exposure to densely ionizing radiation Radiat Res 140 1994 134 142
15. M. Hada, F.A. Cucinotta, S.R. Gonda, and H. Wu MBAND analysis of chromosomal aberrations in human epithelial cells exposed to low- and high-LET radiation Radiat Res 168 2007 98 105
16. E.J. Tawn, C.A. Whitehouse, D. Holdsworth, K. De Ruyck, K. Vandenbulcke, and H. Thierens MBAND analysis of chromosome aberrations in lymphocytes exposed in vitro to alpha-particles and gamma-rays Int J Radiat Biol 84 2008 447 453
17. D. Pignalosa, A. Bertucci, and G. Gialanella Chromosome inter- and intrachanges detected by arm-specific DNA probes in the progeny of human lymphocytes exposed to energetic heavy ions Radiat Res 170 2008 458 466
18. M.P. Hande, T.V. Azizova, and C.R. Geard Past exposure to densely ionizing radiation leaves a unique permanent signature in the genome Am J Hum Genet 72 2003 1162 1170
19. C.R. Mitchell, T.V. Azizova, and M.P. Hande Stable intrachromosomal biomarkers of past exposure to densely ionizing radiation in several chromosomes of exposed individuals Radiat Res 162 2004 257 263
20. M. Horstmann, M. Durante, C. Johannes, R. Pieper, and G. Obe Space radiation does not induce a significant increase of intrachromosomal exchanges in astronauts' lymphocytes Radiat Environ Biophys 44 2005 219 224
21. E.J. Tawn, and C.A. Whitehouse Chromosome intra- and inter-changes determined by G-banding in radiation workers with in vivo exposure to plutonium J Radiol Prot 25 2005 83 88
22. I. Chudoba, G. Hickmann, T. Friedrich, A. Jauch, P. Kozlowski, and G. Senger MBAND: a high resolution multicolor banding technique for the detection of complex intrachromosomal aberrations Cytogenet Genome Res 104 2004 390 393
23. D. Pignalosa, S. Ritter, and M. Durante Inversions in chromosome 10 of human thyroid cells induced by accelerated heavy ions Radiat Res 174 2010 14 19
24. O. Jäkel, M. Krämer, and D. Schulz-Ertner Treatment planning for carbon ion radiotherapy in Germany: review of clinical trials and treatment planning studies Radiother Oncol 73 2004 86 91
25. R. Lee, S. Sommer, C. Hartel, E. Nasonova, M. Durante, and S. Ritter Complex exchanges are responsible for the increased effectiveness of C-ions compared to X-rays at the first post-irradiation mitosis Mutat Res 701 2010 52 59
26. C. Johannes, I. Chudoba, and G. Obe Analysis of X-ray-induced aberrations in human chromosome 5 using high-resolution multicolour banding FISH (mBAND) Chromosome Res 7 1999 625 633
27. S. Ritter, E. Nasonova, M. Scholz, W. Kraft-Weyrather, and G. Kraft Comparison of chromosomal damage induced by X-rays and Ar ions with an LET of 1840 keV/micrometer in G1 V79 cells Int J Radiat Biol 69 1996 155 166
28. M. Hortsmann, M. Durante, C. Johannes, and G. Obe Chromosomal intrachanges induced by swift iron ions Adv Space Res 35 2005 276 279
29. M. Hada, Y. Zhang, A. Feiveson, F.A. Cucinotta, and H. Wu Association of inter- and intrachromosomal exchanges with the distribution of low- and high-LET radiation-induced breaks in chromosomes Radiat Res 176 2011 25 37
30. M. Hada, H. Wu, and F.A. Cucinotta MBAND analysis for high- and low-LET radiation-induced chromosome aberrations: a review Mutat Res 711 2011 187 192
31. J. Surrallés, S. Sebastian, and A.T. Natarajan Chromosomes with high gene density are preferentially repaired in human cells Mutagenesis 12 1997 437 442
32. A. Kiuru, C. Lindholm, A. Auvinen, and S. Salomaa Localization of radiation-induced chromosomal breakpoints along human chromosome 1 using a combination of G-banding and FISH Int J Radiat Biol 76 2000 667 672
33. W. Martínez-López, G.A. Folle, G. Obe, and P. Jeppesen Chromosome regions enriched in hyperacetylated histone H4 are preferred sites for endonuclease- and radiation-induced breakpoints Chromosome Res 9 2001 69 75
34. H.B. Forrester, and I.R. Radford Ionizing radiation-induced chromosomal rearrangements occur in transcriptionally active regions of the genome Int J Radiat Biol 80 2004 757 767
35. W. Martínez-López, E.M. Boccardo, G.A. Folle, V. Porro, and G. Obe Intrachromosomal localization of aberration breakpoints induced by neutrons and gamma rays in Chinese hamster ovary cells Radiat Res 150 1998 585 592
36. W. Martínez-López, and M.V. Di Tomaso Chromatin remodelling and chromosome damage distribution Hum Exp Toxicol 25 2006 539 545
37. W. Martínez-López, G.A. Folle, and G. Cassina Distribution of breakpoints induced by etoposide and X-rays along the CHO X chromosome Cytogenet Genome Res 104 2004 182 187
38. V. d'Alesio, R. Pacelli, and M. Durante Lymph nodes in the irradiated field influence the yield of radiation-induced chromosomal aberrations in lymphocytes from breast cancer patients Int J Radiat Oncol Biol Phys 57 2003 732 738
39. M. Durante, K. George, H. Wu, and F.A. Cucinotta Karyotypes of human lymphocytes exposed to high-energy iron ions Radiat Res 158 2002 581 590
40. K. George, M. Durante, V. Willingham, H. Wu, T.C. Yang, and F.A. Cucinotta Biological effectiveness of accelerated particles for the induction of chromosome damage measured in metaphase and interphase human lymphocytes Radiat Res 160 2003 425 435
41. S. Yamada, M. Durante, and K. Ando Complex-type chromosomal exchanges in blood lymphocytes during radiation therapy correlate with acute toxicity Cancer Lett 150 2000 215 221
42. M.N. Cornforth Analyzing radiation-induced complex chromosome rearrangements by combinatorial painting Radiat Res 155 2001 643 659