β-Lapachone alleviates alcoholic fatty liver disease in rats

Cellular Signalling

Volumn 26, Issue 2, 2014, Pages 295-305

  Shin, Sanghee ^a   Park, Jisoo ^a   Li, Yuwen ^a,b   Min, Ki Nam ^c   Kong, Gyeyeong ^a   Hur, Gang Min ^a   Kim, Jin Man ^a   Shong, Minho ^a   Jung, Min Suk ^c   Park, Jong Kook ^c   Jeong, Kyeong Hoon ^c   Park, Myoung Gyu ^c   Kwak, Tae Hwan ^c   Brazil, Derek P ^d   Park, Jongsun ^a  

^a Chungnam National University   (South Korea)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c Mazence Co Ltd   (South Korea)

^d QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

AMPK; Fatty liver diseases; Metabolic syndrome; PPAR ; Lapachone

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; BETA LAPACHONE; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PHOSPHOLIPID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TRIACYLGLYCEROL;

ALCOHOLIC FATTY LIVER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; DIET; DRUG MECHANISM; ENZYME ACTIVITY; FATTY ACID OXIDATION; GEL MOBILITY SHIFT ASSAY; IMMUNOBLOTTING; LIPID METABOLISM; LIPOLYSIS; LIPOPROTEIN BLOOD LEVEL; LIQUID; LIVER CELL; MALE; MITOCHONDRION; NONHUMAN; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SOLEUS MUSCLE; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION;

ANIMALIA; RATTUS;

AMPK; FATTY LIVER DISEASES; METABOLIC SYNDROME; PPARΑ; Β-LAPACHONE;

ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELLS, CULTURED; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; ETHANOL; FATTY ACIDS; FATTY LIVER, ALCOHOLIC; HEPATOCYTES; LIPID METABOLISM; LIPID PEROXIDATION; LIPIDS; MALE; NAPHTHOQUINONES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE INHIBITORS; SIGNAL TRANSDUCTION;

EID: 84889564061     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.11.020     Document Type: Article

References (41)

1. Albano E. Expert. Rev. Gastroenterol. Hepatol. 2008, 2:749-759.
2. Purohit V., Russo D., Coates P.M. Alcohol (Fayetteville N.Y.) 2004, 34:3-8.
3. Seitz H.K., Lieber C.S., Stickel F., Salaspuro M., Schlemmer H.P., Horie Y. Alcohol. Clin. Exp. Res. 2005, 29:1276-1281.
4. Reuben A. Curr. Opin. Gastroenterol. 2006, 22:263-271.
5. Bentle M.S., Reinicke K.E., Dong Y., Bey E.A., Boothman D.A. Cancer Res. 2007, 67:6936-6945.
6. Schaffner-Sabba K., Schmidt-Ruppin K.H., Wehrli W., Schuerch A.R., Wasley J.W. J. Med. Chem. 1984, 27:990-994.
7. Blanco E., Bey E.A., Dong Y., Weinberg B.D., Sutton D.M., Boothman D.A., Gao J. J. Control. Release 2007, 122:365-374.
8. Choi E.K., Terai K., Ji I.M., Kook Y.H., Park K.H., Oh E.T., Griffin R.J., Lim B.U., Kim J.S., Lee D.S., Boothman D.A., Loren M., Song C.W., Park H.J. Neoplasia New York N.Y. 2007, 9:634-642.
9. Park H.J., Ahn K.J., Ahn S.D., Choi E., Lee S.W., Williams B., Kim E.J., Griffin R., Bey E.A., Bornmann W.G., Gao J., Park H.J., Boothman D.A., Song C.W. Int. J. Radiat. Oncol. Biol. Phys. 2005, 61:212-219.
10. Sun X., Li Y., Li W., Zhang B., Wang A.J., Sun J., Mikule K., Jiang Z., Li C.J. Cell Cycle Georgetown Tex. 2006, 5:2029-2035.
11. Bentle M.S., Reinicke K.E., Bey E.A., Spitz D.R., Boothman D.A. J. Biol. Chem. 2006, 281:33684-33696.
12. Bentle M.S., Bey E.A., Dong Y., Reinicke K.E., Boothman D.A. J. Mol. Hist. 2006, 37:203-218.
13. Hwang J.H., Kim D.W., Jo E.J., Kim Y.K., Jo Y.S., Park J.H., Yoo S.K., Park M.K., Kwak T.H., Kho Y.L., Han J., Choi H.S., Lee S.H., Kim J.M., Lee I., Kyung T., Jang C., Chung J., Kweon G.R., Shong M. Diabetes 2009, 58:965-974.
14. Kim S.Y., Jeoung N.H., Oh C.J., Choi Y.K., Lee H.J., Kim H.J., Kim J.Y., Hwang J.H., Tadi S., Yim Y.H., Lee K.U., Park K.G., Huh S., Min K.N., Jeong K.H., Park M.G., Kwak T.H., Kweon G.R., Inukai K., Shong M., Lee I.K. Circ. Res. 2009, 104(1):842-850.
15. Oh W., Abu-Elheiga L., Kordari P., Gu Z., Shaikenov T., Chirala S.S., Wakil S.J. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:1384-1389.
16. Nakamura T., Yoshimoto K., Nakayama Y., Tomita Y., Ichihara A. Proc. Natl. Acad. Sci. U. S. A. 1983, 80:7229-7233.
17. Fischer M., You M., Matsumoto M., Crabb D.W. J. Biol. Chem. 2003, 278:27997-28004.
18. Jay M.A., Ren J. Curr. Diabetes Rev. 2007, 3:33-39.
19. Li T.K., Yin S.J., Crabb D.W., O'Connor S., Ramchandani V.A. Alcohol. Clin. Exp. Res. 2001, 25:136-144.
20. Ido Y. Antioxid. Redox Signal. 2007, 9:931-942.
21. Ying W. Front. Biosci. 2006, 11:3129-3148.
22. Galli A., Pinaire J., Fischer M., Dorris R., Crabb D.W. J. Biol. Chem. 2001, 276:68-75.
23. Lieber C.S., Jones D.P., Decarli L.M. J. Clin. Invest. 1965, 44:1009-1021.
24. Crabb D.W. Recent Dev. Alcohol. 1993, 11:207-230.
25. Grunnet N., Kondrup J. Alcohol. Clin. Exp. Res. 1986, 10:64S-68S.
26. Salaspuro M.P., Shaw S., Jayatilleke E., Ross W.A., Lieber C.S. Hepatol. Baltim. Md. 1981, 1:33-38.
27. Day C.P., Yeaman S.J. Biochim. Biophys. Acta 1994, 1215:33-48.
28. Grunnet N., Kondrup J., Dich J. Biochem. J. 1985, 228:673-681.
29. Davis R.A., Boogaerts J.R., Borchardt R.A., Malone-McNeal M., Archambault-Schexnayder J. J. Biol. Chem. 1985, 260:14137-14144.
30. Nanji A.A., Zakim D. Hepatology: A Text Book of Liver Disease 1996, 911-913. Saunders, Philadelphia. D. Zakim (Ed.).
31. Eckardt M.J., File S.E., Gessa G.L., Grant K.A., Guerri C., Hoffman P.L., Kalant H., Koob G.F., Li T.K., Tabakoff B. Alcohol. Clin. Exp. Res. 1998, 22:998-1040.
32. Kopun M., Propping P. Eur. J. Clin. Pharmacol. 1977, 11:337-344.
33. Bosron W.F., Ehrig T., Li T.K. Sem. Liver Dis. 1993, 13:126-135.
34. Pink J.J., Planchon S.M., Tagliarino C., Varnes M.E., Siegel D., Boothman D.A. J. Biol. Chem. 2000, 275:5416-5424.
35. Baur J.A., Pearson K.J., Price N.L., Jamieson H.A., Lerin C., Kalra A., Prabhu V.V., Allard J.S., Lopez-Lluch G., Lewis K., Pistell P.J., Poosala S., Becker K.G., Boss O., Gwinn D., Wang M., Ramaswamy S., Fishbein K.W., Spencer R.G., Lakatta E.G., Le Couteur D., Shaw R.J., Navas P., Puigserver P., Ingram D.K., de Cabo R., Sinclair D.A. Nature 2006, 444:337-342.
36. Palming J., Sjoholm K., Jernas M., Lystig T.C., Gummesson A., Romeo S., Lonn L., Lonn M., Carlsson B., Carlsson L.M. J. Clin. Endocrinol. Metab. 2007, 92:2346-2352.
37. Purohit V., Gao B., Song B.J. Alcohol. Clin. Exp. Res. 2009, 33:191-205.
38. Kuhajda F.P., Ronnett G.V. Curr. Opin. Investig. Drugs 2007, 8:312-317.
39. Chinetti-Gbaguidi G., Fruchart J.C., Staels B. Curr. Atheroscler. Rep. 2005, 7:396-401.
40. Hashimoto T., Cook W.S., Qi C., Yeldandi A.V., Reddy J.K., Rao M.S. J. Biol. Chem. 2000, 275:28918-28928.
41. Leone T.C., Weinheimer C.J., Kelly D.P. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:7473-7478.