-
1
-
-
84866181427
-
Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 H1N1 influenza pandemic
-
Xu R, Zhu X, McBride R, et al. Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 H1N1 influenza pandemic. J Virol 2012; 86:9221-9232.
-
(2012)
J Virol
, vol.86
, pp. 9221-9232
-
-
Xu, R.1
Zhu, X.2
McBride, R.3
-
2
-
-
39649114107
-
Medical management of influenza infection
-
Moscona A. Medical management of influenza infection. Annu Rev Med 2008; 59:397-413.
-
(2008)
Annu Rev Med
, vol.59
, pp. 397-413
-
-
Moscona, A.1
-
3
-
-
84871824506
-
Clinical use of approved influenza antivirals: Therapy and prophylaxis
-
Ison MG. Clinical use of approved influenza antivirals: Therapy and prophylaxis. Influenza Other Respi Viruses 2012; 7:7-13.
-
(2012)
Influenza Other Respi Viruses
, vol.7
, pp. 7-13
-
-
Ison, M.G.1
-
4
-
-
80053090644
-
Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
-
Vavricka CJ, Li Q, Wu Y, et al. Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition. PLoS Pathog 2011; 7:e1002249.
-
(2011)
PLoS Pathog
, vol.7
, pp. 1002249
-
-
Vavricka, C.J.1
Li, Q.2
Wu, Y.3
-
5
-
-
84869222897
-
Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus
-
Li Q, Sun X, Li Z, et al. Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus. Proc Natl Acad Sci USA 2012; 109:18897-18902.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 18897-18902
-
-
Li, Q.1
Sun, X.2
Li, Z.3
-
6
-
-
33748437791
-
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
-
Russell RJ, Haire LF, Stevens DJ, et al. The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature 2006; 443:45-49.
-
(2006)
Nature
, vol.443
, pp. 45-49
-
-
Russell, R.J.1
Haire, L.F.2
Stevens, D.J.3
-
7
-
-
84878284641
-
Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: Phylogenetic, structural, and coalescent analyses
-
Liu D, Shi W, Shi Y, et al. Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: Phylogenetic, structural, and coalescent analyses. Lancet 2013; 381:1926-1932.
-
(2013)
Lancet
, vol.381
, pp. 1926-1932
-
-
Liu, D.1
Shi, W.2
Shi, Y.3
-
8
-
-
78049509775
-
A 27-amino-acid deletion in the neuraminidase stalk supports replication of an avian H2N2 influenza A virus in the respiratory tract of chickens
-
Sorrell EM, Song H, Pena L, Perez DR. A 27-amino-acid deletion in the neuraminidase stalk supports replication of an avian H2N2 influenza A virus in the respiratory tract of chickens. J Virol 2010; 84:11831-11840.
-
(2010)
J Virol
, vol.84
, pp. 11831-11840
-
-
Sorrell, E.M.1
Song, H.2
Pena, L.3
Perez, D.R.4
-
9
-
-
84877785371
-
Human infection with a novel avian-origin influenza A (H7N9) virus
-
Gao R, Cao B, Hu Y, et al. Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med 2013; 368:1888-1897.
-
(2013)
N Engl J Med
, vol.368
, pp. 1888-1897
-
-
Gao, R.1
Cao, B.2
Hu, Y.3
-
10
-
-
0026665418
-
The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor
-
Varghese JN, McKimm-Breschkin JL, Caldwell JB, Kortt AA, Colman PM. The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor. Proteins 1992; 14:327-332.
-
(1992)
Proteins
, vol.14
, pp. 327-332
-
-
Varghese, J.N.1
McKimm-Breschkin, J.L.2
Caldwell, J.B.3
Kortt, A.A.4
Colman, P.M.5
-
11
-
-
84879144341
-
Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance
-
Hu Y, Lu S, Song Z, et al. Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance. Lancet 2013; 381:2273-2279.
-
(2013)
Lancet
, vol.381
, pp. 2273-2279
-
-
Hu, Y.1
Lu, S.2
Song, Z.3
-
12
-
-
0032526697
-
Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
-
Varghese JN, Smith PW, Sollis SL, et al. Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure 1998; 6:735-746.
-
(1998)
Structure
, vol.6
, pp. 735-746
-
-
Varghese, J.N.1
Smith, P.W.2
Sollis, S.L.3
-
13
-
-
4444369826
-
Resistant influenza A viruses in children treated with oseltamivir: Descriptive study
-
Kiso M, Mitamura K, Sakai-Tagawa Y, et al. Resistant influenza A viruses in children treated with oseltamivir: Descriptive study. Lancet 2004; 364:759-765.
-
(2004)
Lancet
, vol.364
, pp. 759-765
-
-
Kiso, M.1
Mitamura, K.2
Sakai-Tagawa, Y.3
-
14
-
-
0031787185
-
Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS 4071
-
Tai CY, Escarpe PA, Sidwell RW, et al. Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS 4071. Antimicrob Agents Chemother 1998; 42:3234-3241.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 3234-3241
-
-
Tai, C.Y.1
Escarpe, P.A.2
Sidwell, R.W.3
-
15
-
-
0031000886
-
Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en
-
Gubareva LV, Robinson MJ, Bethell RC, Webster RG. Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en. J Virol 1997; 71:3385-3390.
-
(1997)
J Virol
, vol.71
, pp. 3385-3390
-
-
Gubareva, L.V.1
Robinson, M.J.2
Bethell, R.C.3
Webster, R.G.4
-
16
-
-
25844474747
-
Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility
-
Yen HL, Herlocher LM, Hoffmann E, et al. Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility. Antimicrob Agents Chemother 2005; 49:4075-4084.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 4075-4084
-
-
Yen, H.L.1
Herlocher, L.M.2
Hoffmann, E.3
-
17
-
-
0036224388
-
Influenza virus carrying neuraminidase with reduced sensitivity to oseltamivir carboxylate has altered properties in vitro and is compromised for infectivity and replicative ability in vivo
-
Carr J, Ives J, Kelly L, et al. Influenza virus carrying neuraminidase with reduced sensitivity to oseltamivir carboxylate has altered properties in vitro and is compromised for infectivity and replicative ability in vivo. Antiviral Res 2002; 54:79-88.
-
(2002)
Antiviral Res
, vol.54
, pp. 79-88
-
-
Carr, J.1
Ives, J.2
Kelly, L.3
-
18
-
-
84874604902
-
Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
-
Vavricka CJ, Liu Y, Kiyota H, et al. Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors. Nat Commun 2013; 4:1491.
-
(2013)
Nat Commun
, vol.4
, pp. 1491
-
-
Vavricka, C.J.1
Liu, Y.2
Kiyota, H.3
-
19
-
-
77957767268
-
The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site
-
Li Q, Qi J, Zhang W, et al. The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site. Nat Struct Mol Biol 2010; 17:1266-1268.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1266-1268
-
-
Li, Q.1
Qi, J.2
Zhang, W.3
-
20
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2enderived inhibitors
-
McKimm-Breschkin JL, Sahasrabudhe A, Blick TJ, et al. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2enderived inhibitors. J Virol 1998; 72:2456-2462.
-
(1998)
J Virol
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkin, J.L.1
Sahasrabudhe, A.2
Blick, T.J.3
-
21
-
-
84857190187
-
Antiviral resistance during the 2009 influenza A H1N1 pandemic: Public health, laboratory, and clinical perspectives
-
Hurt AC, Chotpitayasunondh T, Cox NJ, et al. Antiviral resistance during the 2009 influenza A H1N1 pandemic: Public health, laboratory, and clinical perspectives. Lancet Infect Dis 2012; 12:240-248.
-
(2012)
Lancet Infect Dis
, vol.12
, pp. 240-248
-
-
Hurt, A.C.1
Chotpitayasunondh, T.2
Cox, N.J.3
-
22
-
-
2442528187
-
Efficient generation and growth of influenza virus A/PR/8/34 from eight cDNA fragments
-
de Wit E, Spronken MI, Bestebroer TM, Rimmelzwaan GF, Osterhaus AD, Fouchier RA. Efficient generation and growth of influenza virus A/PR/8/34 from eight cDNA fragments. Virus Res 2004; 103:155-161.
-
(2004)
Virus Res
, vol.103
, pp. 155-161
-
-
De Wit, E.1
Spronken, M.I.2
Bestebroer, T.M.3
Rimmelzwaan, G.F.4
Osterhaus, A.D.5
Fouchier, R.A.6
-
23
-
-
79952774962
-
High genetic compatibility and increased pathogenicity of reassortants derived from avian h9n2 and pandemic h1n1 2009 influenza viruses
-
Sun Y, Qin K, Wang J, et al. High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1/2009 influenza viruses. Proc Natl Acad Sci USA 2011; 108:4164-4169.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 4164-4169
-
-
Sun, Y.1
Qin, K.2
Wang, J.3
-
24
-
-
84858751695
-
Molecular and antigenic characterization of h9n2 avian influenza virus isolates from chicken flocks between 1998 and 2007 in China
-
Zhang Y, Yin Y, Bi Y, et al. Molecular and antigenic characterization of H9N2 avian influenza virus isolates from chicken flocks between 1998 and 2007 in China. Vet Microbiol 2012; 156:285-293.
-
(2012)
Vet Microbiol
, vol.156
, pp. 285-293
-
-
Zhang, Y.1
Yin, Y.2
Bi, Y.3
-
25
-
-
33745158157
-
A simple method of estimating fifty percent endpoints
-
Reed LJ, Muench H. A simple method of estimating fifty percent endpoints. Am J Hygiene 1938; 27:493-497.
-
(1938)
Am J Hygiene
, vol.27
, pp. 493-497
-
-
Reed, L.J.1
Muench, H.2
-
26
-
-
55249083577
-
Structural characterization of the 1918 influenza virus H1N1 neuraminidase
-
Xu X, Zhu X, Dwek RA, Stevens J, Wilson IA. Structural characterization of the 1918 influenza virus H1N1 neuraminidase. J Virol 2008; 82:10493-10501.
-
(2008)
J Virol
, vol.82
, pp. 10493-10501
-
-
Xu, X.1
Zhu, X.2
Dwek, R.A.3
Stevens, J.4
Wilson, I.A.5
-
27
-
-
84875763136
-
Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding
-
Wu Y, Qin G, Gao F, et al. Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding. Sci Rep 2013; 3:1551.
-
(2013)
Sci Rep
, vol.3
, pp. 1551
-
-
Wu, Y.1
Qin, G.2
Gao, F.3
-
28
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski Z, Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol 1997; 276:307-326.
-
(1997)
Methods Enzymol
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
29
-
-
0035788107
-
Pushing the boundaries of molecular replacement with maximum likelihood
-
Read RJ. Pushing the boundaries of molecular replacement with maximum likelihood. Acta Crystallogr D Biol Crystallogr 2001; 57:1373-1382.
-
(2001)
Acta Crystallogr D Biol Crystallogr
, vol.57
, pp. 1373-1382
-
-
Read, R.J.1
-
30
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography
-
The CCP4 suite: Programs for protein crystallography. Acta Crystallogr D Biol Crystallogr 1994; 50:760-763.
-
(1994)
Acta Crystallogr D Biol Crystallogr
, vol.50
, pp. 760-763
-
-
-
34
-
-
0000243829
-
Procheck: A program to check the stereochemical quality of protein structures
-
Laskowski R MM, Moss D, Thornton J. PROCHECK: A program to check the stereochemical quality of protein structures. J Appl Cryst 1993; 26:283-291.
-
(1993)
J Appl Cryst
, vol.26
, pp. 283-291
-
-
Laskowski, R.M.M.1
Moss, D.2
Thornton, J.3
-
35
-
-
0018421350
-
Fluorometric assay of neuraminidase with a sodium (4-methylumbelliferyl- alpha-D-N-acetylneuraminate) substrate
-
Potier M, Mameli L, Belisle M, Dallaire L, Melancon SB. Fluorometric assay of neuraminidase with a sodium (4-methylumbelliferyl-alpha-D-N- acetylneuraminate) substrate. Anal Biochem 1979; 94:287-296.
-
(1979)
Anal Biochem
, vol.94
, pp. 287-296
-
-
Potier, M.1
Mameli, L.2
Belisle, M.3
Dallaire, L.4
Melancon, S.B.5
|