BRAF mutation in sporadic colorectal cancer and Lynch syndrome

Virchows Archiv

Volumn 463, Issue 5, 2013, Pages 613-621

  Thiel, Alexandra ^a,b   Heinonen, Mira ^a,b   Kantonen, Jonas ^a,b   Gylling, Annette ^b   Lahtinen, Laura ^c   Korhonen, Mari ^a   Kytölä, Soili ^a   Mecklin, Jukka Pekka ^d   Orpana, Arto ^a   Peltomäki, Päivi ^b   Ristimäki, Ari ^a,b  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c Central Finland Central Hospital   (Finland)

^d UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

BRAF; Colorectal cancer; Lynch syndrome; Methylation; Microsatellite instability; MLH1

Indexed keywords

B RAF KINASE; MONOCLONAL ANTIBODY; PROTEIN MLH1;

ADULT; ARTICLE; BRAF GENE; COLORECTAL CANCER; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; GENE; GENE AMPLIFICATION; GENE MUTATION; GENE SEQUENCE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; METHYLATION; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY;

ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS B-RAF; YOUNG ADULT;

EID: 84889097025     PISSN: 09456317     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/s00428-013-1470-9     Document Type: Article

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