Efficient targeted pDNA/siRNA delivery with folate-low-molecular-weight polyethyleneimine-modified pullulan as non-viral carrier

Materials Science and Engineering C

Volumn 34, Issue 1, 2014, Pages 98-109

  Wang, Jingyun ^a   Dou, Bairui ^a   Bao, Yongming ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Folate; Non virus gene vector; Polyethyleneimine; Pullulan; siRNA

Indexed keywords

FOLATE; GENE VECTORS; POLYETHYLENEIMINE; PULLULANS; SIRNA;

BODY FLUIDS; ELECTROPHORESIS; GENE TRANSFER; MOLECULAR BIOLOGY; NUCLEIC ACIDS; VIRUSES;

GENES;

DEOXYRIBONUCLEASE I; DNA; DRUG CARRIER; FOLIC ACID; GLUCAN; GREEN FLUORESCENT PROTEIN; POLYETHYLENEIMINE; PULLULAN; SMALL INTERFERING RNA;

AGAR GEL ELECTROPHORESIS; ARTICLE; CELL DEATH; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; FLOW CYTOMETRY; GENE SILENCING; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; INTRACELLULAR SPACE; METABOLISM; NON-VIRUS GENE VECTOR; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEASE PROTECTION ASSAY; PLASMID; SYNTHESIS; ULTRAVIOLET SPECTROPHOTOMETRY;

FOLATE; NON-VIRUS GENE VECTOR; POLYETHYLENEIMINE; PULLULAN; SIRNA;

CELL DEATH; CELL LINE; CELL SURVIVAL; DEOXYRIBONUCLEASE I; DNA; DRUG CARRIERS; ELECTROPHORESIS, AGAR GEL; FLOW CYTOMETRY; FOLIC ACID; GENE SILENCING; GENE TRANSFER TECHNIQUES; GLUCANS; GREEN FLUORESCENT PROTEINS; HUMANS; INTRACELLULAR SPACE; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEASE PROTECTION ASSAYS; PLASMIDS; POLYETHYLENEIMINE; RNA, SMALL INTERFERING; SPECTROPHOTOMETRY, ULTRAVIOLET; TRANSFECTION;

EID: 84889093944     PISSN: 09284931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.msec.2013.08.035     Document Type: Article

References (31)

1. X. Peisheng, K.Q. Griffin, and Y. Yoon Gene delivery through the use of a hyaluronate-associated intracellularly degradable crosslinked polyethyleneimine Biomaterials 30 2009 5834 5843
2. D.G. Anderson, W.D. Peng, A. Akinc, N. Hossain, A. Kohn, R. Padera, R. Langer, and J.A. Sawicki A polymer library approach to suicide gene therapy for cancer Proc. Natl. Acad. Sci. U. S. A. 101 2004 16028 16033 (Pubitemid 39507921)
3. W.P. Colin, and W.S. Leonard Key issues in non-viral gene delivery Adv. Drug Deliv. Rev. 46 2001 187 203
4. S. Nayak, and R.W. Herzog Progress and prospects: immune responses to viral vectors Gene Ther. 17 2010 295 304
5. S. Son, D.W. Hwang, J.H. Jeong, D.S. Lee, T.G. Park, K. Singha, and W.J. Kim RVG peptide tethered bioreducible polyethylenimine for gene delivery to brain J. Control. Release 155 2011 18 25
6. A.C. Rodrigo, I. Rivilla, F.C. Perez-Martínez, S. Monteagudo, V. Ocana, J. Guerra, J.C. Garcia-Martinez, S. Merino, P. Sanchez-Verdu, V. Cena, and J. Rodriguez-Lopez Efficient non-toxic hybrid PPV-PAMAM dendrimer as a gene carrier for neuronal cells Biomacromolecules 12 2011 1205 1213
7. S.M. Noh, S.E. Han, G. Shim, K.E. Lee, C.W. Kim, S.S. Han, Y. Choi, Y.K. Kim, W.K. Kim, and Y.K. Oh Tocopheryl oligochitosan-based self assembling oligomersomes for siRNA delivery Biomaterials 32 2011 849 857
8. F.Y. Dai, and W.G. Liu Enhanced gene transfection and serum stability of polyplexes by PDMAEMA-polysulfobetaine diblock copolymers Biomaterials 32 2011 1943 1949
9. C.O. Mellet, J.M. GarcIa Fernandez, and J.M. Benito Cyclodextrin-based gene delivery systems Chem. Soc. Rev. 40 2011 1586 1608
10. R. Kircheis, L. Wightman, and E. Wagner Design and gene delivery activity of modified polyethylenimines Adv. Drug Deliv. Rev. 53 2001 341 358 (Pubitemid 34024914)
11. W.T. Godbey, K.K. Wu, and A.G. Mikos Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle J. Biomed. Mater. Res. 5 1999 168 175
12. B. Lu, X.D. Xu, X.Z. Zhang, S.X. Cheng, and R.X. Zhuo Low molecular weight polyethylenimine grafted N-maleated chitosan for gene delivery: properties and in vitro transfection studies Biomacromolecules 9 2008 2594 2600
13. D. Li, Y.A. Ping, F.J. Xu, H. Yu, H.M. Pan, H.L. Huang, Q.Q. Wang, G.P. Tang, and J. Li Construction of a star-shaped copolymer as a vector for FGF receptor-mediated gene delivery in vitro and in vivo Biomacromolecules 11 2010 2221 2229
14. F. Zhao, H. Yin, Z.X. Zhang, and J. Li Folic acid modified cationic γ-cyclodextrin-oligoethylenimine star polymer with bioreducible disulfide linker for efficient targeted gene delivery Biomacromolecules 14 2013 476 484
15. Y.X. Sun, W. Xiao, S.X. Cheng, X.Z. Zhang, and R.X. Zhuo Synthesis of (Dex-HMDI)-g-PEIs as effective and low cytotoxic nonviral gene vectors J. Control. Release 128 2008 171 178
16. M.S. Huh, S.Y. Lee, S. Park, S. Lee, H. Chung, S. Lee, Y. Choi, Y.K. Oh, J.H. Park, S.Y. Jeong, K. Choi, K. Kim, and I.C. Kwon Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice J. Control. Release 144 2010 134 143
17. G. Fundueanu, M. Constantin, I. Oanea, V. Harabagiu, P. Ascenzi, and B.C. Simionescu Entrapment and release of drugs by a strict "on-off" mechanism in pullulan microspheres with pendant thermosensitive groups Biomaterials 31 2010 9544 9553
18. S. Seo, C.S. Lee, Y.S. Jung, and K. Na Thermo-sensitivity and triggered drug release of polysaccharide nanogels derived from pullulan-g-poly(l-lactide) copolymers Carbohydr. Polym. 87 2012 1105 1111
19. J. Jo, M. Yamamoto, K. Matsumoto, T. Nakamura, and Y. Tabata Liver targeting of plasmid DNA with a cationized pullulan for tumor supression J. Nanosci. Nanotechnol. 6 2006 2853 2859 (Pubitemid 44579955)
20. L.B. Thomsen, J. Lichota, K.S. Kim, and T. Moos Gene delivery by pullulan derivatives in brain capillary endothelial cells for protein secretion J. Control. Release 151 2011 45 50
21. D.K. Thakor, Y.D. Teng, and Y. Tabata Neuronal gene delivery by negatively charged pullulan-spermine/DNA anioplexes Biomaterials 30 2009 1815 1826
22. M.R. Rekha, and C.P. Sharma Hemocompatible pullulan-polyethyleneimine conjugates for liver cell gene delivery: in vitro evaluation of cellular uptake, intracellular trafficking and transfection efficiency Acta Biomater. 7 2011 370 379
23. M.R. Rekha, and C.P. Sharma Blood compatibility and in vitro transfection studies on cationically modified pullulan for liver cell targeted gene delivery Biomaterials 30 2009 6655 6664
24. J.A. Reddy, C. Abburi, H. Hofland, S.J. Howard, I. Vlahov, P. Wils, and C.P. Leamon Folate targeted cationic liposome-mediated gene transfer into disseminated peritoneal tumors Gene Ther. 9 2002 1542 1550
25. V.B. Morris, and C.P. Sharma Folate mediated l-arginine modified oligo (alkylaminosiloxane) graft poly (ethyleneimine) for tumor targeted gene delivery Biomaterials 32 2011 3030 3041
26. H. Uchida, T. Tanaka, K. Sasaki, K. Kato, H. Dehari, Y. Ito, M. Kobune, M. Miyagishi, K. Taira, H. Tahara, and H. Hamada Adenovirus-mediated transfer of siRNA against surviving induced apoptosis and attenuated tumor cell growth in vitro and in vivo Mol. Ther. 10 2004 162 171 (Pubitemid 38878158)
27. E.L. Ferguson, and R. Duncan Dextrin-phospholipase A2: synthesis and evaluation as a bioresponsive anticancer conjugate Biomacromolecules 10 2009 1358 1364
28. D. Bumcrot, M. Manoharan, V. Koteliansky, and D.W.Y. Sah RNAi therapeutica: a potential new class of pharmaceutical drugs Nat. Chem. Biol. 2 2006 711 719 (Pubitemid 44764213)
29. B.M. Godinho, J.R. Oqier, R. Daracy, C.M. O'Driscoll, and J.F. Cryan Self-assembling modified β-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: focus on Huntington's disease Mol. Pharm. 10 2013 640 649
30. X.Q. Liu, C.Y. Sun, X.Z. Yang, and J. Wang Polymeric-micelle-based nanomedicine for siRNA delivery Part. Part. Syst. Charact. 30 2013 211 228
31. W.T. Godbey, K.K. Wu, and A.G. Mikos Poly(ethylenimine) and its role in gene delivery J. Control. Release 60 1999 149 160 (Pubitemid 29335941)