Gene delivery by pullulan derivatives in brain capillary endothelial cells for protein secretion

Journal of Controlled Release

Volumn 151, Issue 1, 2011, Pages 45-50

  Thomsen, Louiza Bohn ^a   Lichota, Jacek ^a   Kim, Kwang Sik ^b   Moos, Torben ^a  

^a AALBORG UNIVERSITY   (Denmark)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

blood brain barrier; Gene expression; Gene therapy; Pullulan; Spermine

Indexed keywords

BLOOD-BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELLS; CDNA ENCODING; DELIVERY SYSTEMS; GENE DELIVERY; GENETIC MATERIALS; GROWTH MEDIUM; HARMFUL SUBSTANCES; HUMAN BRAIN; HUMAN GROWTH HORMONE; IN-VIVO; NATURALLY OCCURRING; NONVIRAL; PLASMID DNA; POLYAMINES; PROTEIN EXPRESSIONS; PROTEIN SECRETION; PULLULANS; RAT BRAIN; RECOMBINANT PROTEIN PRODUCTIONS; SPERMINE; TRANSPORT PROTEINS;

BIOMOLECULES; BLOOD; BLOOD VESSELS; DNA; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; NUCLEIC ACIDS; PHYSIOLOGY; PROTEINS;

ENDOTHELIAL CELLS;

COMPLEMENTARY DNA; HUMAN GROWTH HORMONE; HUMAN GROWTH HORMONE 1; PLASMID DNA; PULLULAN; RECOMBINANT PROTEIN; RED FLUORESCENT PROTEIN; SPERMINE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ARTICLE; BRAIN CAPILLARY; CULTURE MEDIUM; ENDOTHELIUM CELL; FEMALE; GENE TARGETING; HUMAN; HUMAN CELL; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

ADULT; BLOOD-BRAIN BARRIER; CELLS, CULTURED; DNA; ENDOTHELIAL CELLS; FEMALE; GLUCANS; GROWTH HORMONE; HUMANS; RECOMBINANT PROTEINS; SPERMINE; TRANSFECTION;

EID: 79955484620     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.01.002     Document Type: Article

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