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Volumn 18, Issue 12, 2013, Pages 1513-1525

Prohibitin (PHB) inhibits apoptosis in rat granulosa cells (GCs) through the extracellular signal-regulated kinase 1/2 (ERK1/2) and the Bcl family of proteins

Author keywords

Apoptosis; Granulosa cells; Mitochondria; Prohibitin; Survival

Indexed keywords

CYTOCHROME C; GONADOTROPIN; MITOGEN ACTIVATED PROTEIN KINASE 3; PROHIBITIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; STAUROSPORINE;

EID: 84889072506     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0901-z     Document Type: Article
Times cited : (41)

References (39)
  • 1
    • 0030934805 scopus 로고    scopus 로고
    • Regulation of ovarian follicle atresia
    • 9074768 10.1146/annurev.physiol.59.1.349 1:CAS:528:DyaK2sXhvVSjtLk%3D
    • Kaipia A, Hsueh AJ (1997) Regulation of ovarian follicle atresia. Annu Rev Physiol 59:349-363
    • (1997) Annu Rev Physiol , vol.59 , pp. 349-363
    • Kaipia, A.1    Hsueh, A.J.2
  • 2
    • 0141813268 scopus 로고    scopus 로고
    • Regulation of cell death and cell survival gene expression during ovarian follicular development and atresia
    • 12456353 10.2741/949 1:CAS:528:DC%2BD3sXhsVejs74%3D
    • Jiang JY, Cheung CK, Wang Y, Tsang BK (2003) Regulation of cell death and cell survival gene expression during ovarian follicular development and atresia. Front Biosci 8:d222-d237
    • (2003) Front Biosci , vol.8
    • Jiang, J.Y.1    Cheung, C.K.2    Wang, Y.3    Tsang, B.K.4
  • 3
    • 0028148597 scopus 로고
    • In situ localization of apoptosis in the rat ovary during follicular atresia
    • 7531507 10.1095/biolreprod51.5.888 1:CAS:528:DyaK2cXmsFejs7s%3D
    • Palumbo A, Yeh J (1994) In situ localization of apoptosis in the rat ovary during follicular atresia. Biol Reprod 51(5):888-895
    • (1994) Biol Reprod , vol.51 , Issue.5 , pp. 888-895
    • Palumbo, A.1    Yeh, J.2
  • 4
    • 0029821661 scopus 로고    scopus 로고
    • Apoptosis occurs in granulosa cells but not cumulus cells in the atretic antral follicles in pig ovaries
    • 8698104 10.1007/BF01925566 1:CAS:528:DyaK28Xkslymtbc%3D
    • Manabe N, Imai Y, Ohno H, Takahagi Y, Sugimoto M, Miyamoto H (1996) Apoptosis occurs in granulosa cells but not cumulus cells in the atretic antral follicles in pig ovaries. Experientia 52(7):647-651
    • (1996) Experientia , vol.52 , Issue.7 , pp. 647-651
    • Manabe, N.1    Imai, Y.2    Ohno, H.3    Takahagi, Y.4    Sugimoto, M.5    Miyamoto, H.6
  • 6
    • 33846445804 scopus 로고    scopus 로고
    • Current concepts in apoptosis: The physiological suicide program revisited
    • 16977376 10.2478/s11658-006-0041-3 1:CAS:528:DC%2BD2sXhtF2lurY%3D
    • Chowdhury I, Tharakan B, Bhat GK (2006) Current concepts in apoptosis: the physiological suicide program revisited. Cell Mol Biol Lett 11(4):506-525
    • (2006) Cell Mol Biol Lett , vol.11 , Issue.4 , pp. 506-525
    • Chowdhury, I.1    Tharakan, B.2    Bhat, G.K.3
  • 8
    • 33845878868 scopus 로고    scopus 로고
    • Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin
    • 17038561 10.1210/en.2006-0187 1:CAS:528:DC%2BD2sXjsV2quw%3D%3D
    • Chowdhury I, Xu W, Stiles JK, Zeleznik A, Yao X, Matthews R, Thomas K, Thompson WE (2007) Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin. Endocrinology 148(1):206-217
    • (2007) Endocrinology , vol.148 , Issue.1 , pp. 206-217
    • Chowdhury, I.1    Xu, W.2    Stiles, J.K.3    Zeleznik, A.4    Yao, X.5    Matthews, R.6    Thomas, K.7    Thompson, W.E.8
  • 9
    • 80051688824 scopus 로고    scopus 로고
    • Prohibitin (PHB) acts as a potent survival factor against ceramide induced apoptosis in rat granulosa cells
    • 21763324 10.1016/j.lfs.2011.06.022 1:CAS:528:DC%2BC3MXhtVWqu7fE
    • Chowdhury I, Branch A, Olatinwo M, Thomas K, Matthews R, Thompson WE (2011) Prohibitin (PHB) acts as a potent survival factor against ceramide induced apoptosis in rat granulosa cells. Life Sci 89(9-10):295-303
    • (2011) Life Sci , vol.89 , Issue.9-10 , pp. 295-303
    • Chowdhury, I.1    Branch, A.2    Olatinwo, M.3    Thomas, K.4    Matthews, R.5    Thompson, W.E.6
  • 11
    • 0033883489 scopus 로고    scopus 로고
    • Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos
    • 10906068 10.1095/biolreprod63.2.582 1:CAS:528:DC%2BD3cXltl2gurw%3D
    • Sutovsky P, Moreno RD, Ramalho-Santos J, Dominko T, Simerly C, Schatten G (2000) Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos. Biol Reprod 63:582-590
    • (2000) Biol Reprod , vol.63 , pp. 582-590
    • Sutovsky, P.1    Moreno, R.D.2    Ramalho-Santos, J.3    Dominko, T.4    Simerly, C.5    Schatten, G.6
  • 12
    • 0037774827 scopus 로고    scopus 로고
    • Ubiquitination of prohibitin in mammalian sperm mitochondria: Possible roles in the regulation of mitochondrial inheritance and sperm quality control
    • 12646488 10.1095/biolreprod.102.010975 1:CAS:528:DC%2BD3sXkvFCntb4%3D
    • Thompson WE, Ramalho-Santos J, Sutovsky P (2003) Ubiquitination of prohibitin in mammalian sperm mitochondria: possible roles in the regulation of mitochondrial inheritance and sperm quality control. Biol Reprod 69(1):254-260
    • (2003) Biol Reprod , vol.69 , Issue.1 , pp. 254-260
    • Thompson, W.E.1    Ramalho-Santos, J.2    Sutovsky, P.3
  • 13
    • 0034861350 scopus 로고    scopus 로고
    • Characterization of prohibitin in a newly established rat ovarian granulosa cell line
    • 11517187 10.1210/en.142.9.4076 1:CAS:528:DC%2BD3MXmsFSgsb0%3D
    • Thompson WE, Branch A, Whittaker JA, Lyn D, Zilberstein M, Mayo KE, Thomas K (2001) Characterization of prohibitin in a newly established rat ovarian granulosa cell line. Endocrinology 142:4076-4085
    • (2001) Endocrinology , vol.142 , pp. 4076-4085
    • Thompson, W.E.1    Branch, A.2    Whittaker, J.A.3    Lyn, D.4    Zilberstein, M.5    Mayo, K.E.6    Thomas, K.7
  • 14
    • 0032771723 scopus 로고    scopus 로고
    • Immunolocalization and expression of prohibitin, a mitochondrial associated protein within the rat ovaries
    • 10456984 10.1002/(SICI)1097-0185(19990901)256:1<40: AID-AR6>3.0.CO;2-X 1:CAS:528:DyaK1MXmtVyrt78%3D
    • Thompson WE, Powell JM, Whittaker JA, Sridaran R, Thomas KH (1999) Immunolocalization and expression of prohibitin, a mitochondrial associated protein within the rat ovaries. Anat Rec 256:40-48
    • (1999) Anat Rec , vol.256 , pp. 40-48
    • Thompson, W.E.1    Powell, J.M.2    Whittaker, J.A.3    Sridaran, R.4    Thomas, K.H.5
  • 15
    • 0034910826 scopus 로고    scopus 로고
    • Staurosporine inhibits phosphorylation of translational regulators linked to mTOR
    • 11526437 10.1038/sj.cdd.4400876 1:CAS:528:DC%2BD3MXmtFCjs74%3D
    • Tee AR, Proud CG (2001) Staurosporine inhibits phosphorylation of translational regulators linked to mTOR. Cell Death Differ 8(8):841-849
    • (2001) Cell Death Differ , vol.8 , Issue.8 , pp. 841-849
    • Tee, A.R.1    Proud, C.G.2
  • 16
    • 68549112851 scopus 로고    scopus 로고
    • Induction of apoptosis by staurosporine involves the inhibition of expression of the major cell cycle proteins at the G(2)/m checkpoint accompanied by alterations in Erk and Akt kinase activities
    • 19661292 1:CAS:528:DC%2BD1MXhtVekurbP
    • Antonsson A, Persson JL (2009) Induction of apoptosis by staurosporine involves the inhibition of expression of the major cell cycle proteins at the G(2)/m checkpoint accompanied by alterations in Erk and Akt kinase activities. Anticancer Res 29(8):2893-2898
    • (2009) Anticancer Res , vol.29 , Issue.8 , pp. 2893-2898
    • Antonsson, A.1    Persson, J.L.2
  • 17
    • 0035014977 scopus 로고    scopus 로고
    • Adenovirus-directed expression of functional luteinizing hormone (LH) receptors in undifferentiated rat granulosa cells: Evidence for differential signaling through follicle-stimulating hormone and LH receptors
    • 11356670 10.1210/en.142.6.2252 1:CAS:528:DC%2BD3MXjvFGgurg%3D
    • Bebia Z, Somers JP, Liu G, Ihrig L, Shenker A, Zeleznik AJ (2001) Adenovirus-directed expression of functional luteinizing hormone (LH) receptors in undifferentiated rat granulosa cells: evidence for differential signaling through follicle-stimulating hormone and LH receptors. Endocrinology 142(6):2252-2259
    • (2001) Endocrinology , vol.142 , Issue.6 , pp. 2252-2259
    • Bebia, Z.1    Somers, J.P.2    Liu, G.3    Ihrig, L.4    Shenker, A.5    Zeleznik, A.J.6
  • 18
    • 0033304575 scopus 로고    scopus 로고
    • Adenovirus-directed expression of a nonphosphorylatable mutant of CREB (cAMP response element-binding protein) adversely affects the survival, but not the differentiation, of rat granulosa cells
    • 10446909 10.1210/me.13.8.1364 1:CAS:528:DyaK1MXltVChsrY%3D
    • Somers JP, DeLoia JA, Zeleznik AJ (1999) Adenovirus-directed expression of a nonphosphorylatable mutant of CREB (cAMP response element-binding protein) adversely affects the survival, but not the differentiation, of rat granulosa cells. Mol Endocrinol 13:1364-1372
    • (1999) Mol Endocrinol , vol.13 , pp. 1364-1372
    • Somers, J.P.1    Deloia, J.A.2    Zeleznik, A.J.3
  • 19
    • 0033832590 scopus 로고    scopus 로고
    • Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2-ratio and loss of spontaneous caspase-3 processing in vivo
    • 10995007 10.1038/sj.leu.2401866 1:CAS:528:DC%2BD3cXntFOhtr8%3D
    • Prokop A, Wieder T, Sturm I, Essmann F, Seeger K, Wuchter C, Ludwig WD, Henze G, Dörken B, Daniel PT (2000) Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2-ratio and loss of spontaneous caspase-3 processing in vivo. Leukemia 14:1606-1613
    • (2000) Leukemia , vol.14 , pp. 1606-1613
    • Prokop, A.1    Wieder, T.2    Sturm, I.3    Essmann, F.4    Seeger, K.5    Wuchter, C.6    Ludwig, W.D.7    Henze, G.8    Dörken, B.9    Daniel, P.T.10
  • 21
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • 17496923 10.1038/sj.onc.1210422 1:CAS:528:DC%2BD2sXlt1Wktb4%3D
    • Roberts PJ, Der CJ (2007) Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26(22):3291-3310
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 22
    • 84859118348 scopus 로고    scopus 로고
    • Follicular growth and atresia in mammalian ovaries: Regulation by survival and death of granulosa cells
    • 22450284 10.1262/jrd.2011-012 1:CAS:528:DC%2BC38XlvVOntr0%3D
    • Matsuda F, Inoue N, Manabe N, Ohkura S (2012) Follicular growth and atresia in mammalian ovaries: regulation by survival and death of granulosa cells. J Reprod Dev 58(1):44-50
    • (2012) J Reprod Dev , vol.58 , Issue.1 , pp. 44-50
    • Matsuda, F.1    Inoue, N.2    Manabe, N.3    Ohkura, S.4
  • 24
    • 81555202995 scopus 로고    scopus 로고
    • Bilateral aggressive malignant granulosa cell tumour with essentially different immunophenotypes in primary and metastatic lesions comprising predominantly sarcomatoid and fibrothecomatous patterns - Looking for prognostic markers: A case report
    • 22291843 10.5114/aoms.2011.25573
    • Jozwicki W, Brożyna AA, Walentowicz M, Grabiec M (2011) Bilateral aggressive malignant granulosa cell tumour with essentially different immunophenotypes in primary and metastatic lesions comprising predominantly sarcomatoid and fibrothecomatous patterns - looking for prognostic markers: a case report. Arch Med Sci 7(5):918-922
    • (2011) Arch Med Sci , vol.7 , Issue.5 , pp. 918-922
    • Jozwicki, W.1    Brozyna, A.A.2    Walentowicz, M.3    Grabiec, M.4
  • 25
    • 40949118906 scopus 로고    scopus 로고
    • Intrabursal administration of the antiangiopoietin 1 antibody produces a delay in rat follicular development associated with an increase in ovarian apoptosis mediated by changes in the expression of BCL2 related genes
    • 17989359 10.1095/biolreprod.107.063610 1:CAS:528:DC%2BD1cXisFSlurg%3D
    • Parborell F, Abramovich D, Tesone M (2008) Intrabursal administration of the antiangiopoietin 1 antibody produces a delay in rat follicular development associated with an increase in ovarian apoptosis mediated by changes in the expression of BCL2 related genes. Biol Reprod 78(3):506-513
    • (2008) Biol Reprod , vol.78 , Issue.3 , pp. 506-513
    • Parborell, F.1    Abramovich, D.2    Tesone, M.3
  • 27
    • 33644763109 scopus 로고    scopus 로고
    • Molecular targeting of BCL2 and BCLXL proteins by synthetic BCL2 homology 3 domain peptide enhances the efficacy of chemotherapy
    • 16291730 10.1124/jpet.105.094243 1:CAS:528:DC%2BD28Xit1Shurc%3D
    • Dharap SS, Chandna P, Wang Y, Khandare JJ, Qiu B, Stein S, Minko T (2006) Molecular targeting of BCL2 and BCLXL proteins by synthetic BCL2 homology 3 domain peptide enhances the efficacy of chemotherapy. J Pharmacol Exp Ther 316(3):992-998
    • (2006) J Pharmacol Exp Ther , vol.316 , Issue.3 , pp. 992-998
    • Dharap, S.S.1    Chandna, P.2    Wang, Y.3    Khandare, J.J.4    Qiu, B.5    Stein, S.6    Minko, T.7
  • 28
    • 0037155927 scopus 로고    scopus 로고
    • MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c release
    • 11756439 10.1074/jbc.M108366200 1:CAS:528:DC%2BD38XisVyks7Y%3D
    • Gibson EM, Henson ES, Villanueva J, Gibson SB (2002) MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c release. J Biol Chem 277(12):10573-10580
    • (2002) J Biol Chem , vol.277 , Issue.12 , pp. 10573-10580
    • Gibson, E.M.1    Henson, E.S.2    Villanueva, J.3    Gibson, S.B.4
  • 29
    • 0033026714 scopus 로고    scopus 로고
    • Mechanisms of apoptosis avoidance in cancer
    • 9914881 10.1097/00001622-199901000-00014 1:CAS:528:DyaK1MXhvVGns7s%3D
    • Reed JC (1999) Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 11(1):68-75
    • (1999) Curr Opin Oncol , vol.11 , Issue.1 , pp. 68-75
    • Reed, J.C.1
  • 30
    • 34548095336 scopus 로고    scopus 로고
    • Ras-Raf signaling needs prohibitin
    • 16294014 10.4161/cc.4.11.2142 1:CAS:528:DC%2BD28XktVCgsLo%3D
    • Rajalingam K, Rudel T (2005) Ras-Raf signaling needs prohibitin. Cell Cycle 4(11):1503-1505
    • (2005) Cell Cycle , vol.4 , Issue.11 , pp. 1503-1505
    • Rajalingam, K.1    Rudel, T.2
  • 31
    • 23144455311 scopus 로고    scopus 로고
    • Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration
    • 16041367 10.1038/ncb1283 1:CAS:528:DC%2BD2MXmvVCluro%3D
    • Rajalingam K, Wunder C, Brinkmann V, Churin Y, Hekman M, Sievers C, Rapp UR, Rudel T (2005) Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration. Nat Cell Biol 7(8):837-843
    • (2005) Nat Cell Biol , vol.7 , Issue.8 , pp. 837-843
    • Rajalingam, K.1    Wunder, C.2    Brinkmann, V.3    Churin, Y.4    Hekman, M.5    Sievers, C.6    Rapp, U.R.7    Rudel, T.8
  • 32
    • 77955965172 scopus 로고    scopus 로고
    • Cellular stress responses: Cell survival and cell death
    • Fulda S, Gorman AM, Hori O, Samali A (2010) Cellular stress responses: cell survival and cell death. Int J Cell Biol 10:1-23
    • (2010) Int J Cell Biol , vol.10 , pp. 1-23
    • Fulda, S.1    Gorman, A.M.2    Hori, O.3    Samali, A.4
  • 34
    • 34250204271 scopus 로고    scopus 로고
    • The machines that divide and fuse mitochondria
    • 17362197 10.1146/annurev.biochem.76.071905.090048 1:CAS:528: DC%2BD2sXhtVehtbzF
    • Hoppins S, Lackner L, Nunnari J (2007) The machines that divide and fuse mitochondria. Annu Rev Biochem 76:751-780
    • (2007) Annu Rev Biochem , vol.76 , pp. 751-780
    • Hoppins, S.1    Lackner, L.2    Nunnari, J.3
  • 35
    • 0043166392 scopus 로고    scopus 로고
    • Dynamics of mitochondrial morphology in healthy cells and during apoptosis
    • 10.1038/sj.cdd.4401260
    • Karabowski M, Youle RJ (2003) Dynamics of mitochondrial morphology in healthy cells and during apoptosis. Cell Death Differ 8:870-880
    • (2003) Cell Death Differ , vol.8 , pp. 870-880
    • Karabowski, M.1    Youle, R.J.2
  • 36
    • 33845970253 scopus 로고    scopus 로고
    • Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2
    • 17008324 10.1074/jbc.M605260200 1:CAS:528:DC%2BD28Xht1ajt7zF
    • Kasashima K, Ohta E, Kagawa Y, Endo H (2006) Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2. J Biol Chem 281:36401-36410
    • (2006) J Biol Chem , vol.281 , pp. 36401-36410
    • Kasashima, K.1    Ohta, E.2    Kagawa, Y.3    Endo, H.4
  • 38
    • 40749104734 scopus 로고    scopus 로고
    • Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis
    • 18183577 10.1002/ijc.23351 1:CAS:528:DC%2BD1cXkt1Chs74%3D
    • Gregory-Bass RC, Olatinwo M, Xu W, Matthews R, Stiles JK, Thomas K, Liu D, Tsang B, Thompson WE (2008) Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis. Int J Cancer 122(9):1923-1930
    • (2008) Int J Cancer , vol.122 , Issue.9 , pp. 1923-1930
    • Gregory-Bass, R.C.1    Olatinwo, M.2    Xu, W.3    Matthews, R.4    Stiles, J.K.5    Thomas, K.6    Liu, D.7    Tsang, B.8    Thompson, W.E.9
  • 39


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