Adenovirus-directed expression of functional luteinizing hormone (LH) receptors in undifferentiated rat granulosa cells: Evidence for differential signaling through follicle-stimulating hormone and LH receptors

Endocrinology

Volumn 142, Issue 6, 2001, Pages 2252-2259

  Bebia, Zourab ^a   Somers, Jeremy P ^a   Liu, Guoquan ^b   Ihrig, Lynda ^a,b   Shenker, Andrew ^b   Zeleznik, Anthony J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; ESTROGEN; FOLLITROPIN RECEPTOR; LUTEINIZING HORMONE RECEPTOR; MESSENGER RNA; PROGESTERONE; STEROID; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; ESTROGEN SYNTHESIS; FEMALE; GRANULOSA CELL; HORMONAL REGULATION; HORMONE BINDING; NONHUMAN; PRIORITY JOURNAL; PROGESTERONE SYNTHESIS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STEROIDOGENESIS;

EID: 0035014977     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.142.6.8017     Document Type: Article

References (44)

1. 1. Zeleznik AJ, Benyo DF 1994 Control of follicular development, corpus luteum function, and recognition of pregnancy in higher primates. In: Knobil E, Neill JD (eds) Physiology of Reproduction, Ed 2. Raven Press, New York, vol 2:751-782
2. 2. Richards JS 1994 Hormonal control of gene expression in the ovary. Endocr Rev 15:725-751
3. 3. Adashi EY, Resnick CE 1986 3′5′-cyclic adenosine monophosphate as an intracellular second messenger of luteinizing hormone: application of forskolin criteria. J Cell Biochem 31:217-228
4. 4. Richards JS, Jonassen JA, Rolfes AI, Kersey K, Reichert Jr LE 1979 Adenosine 3′,5′-monophosphate, luteinizing hormone receptor, and progesterone during granulosa cell differentiation: effects of estradiol and follicle-stimulating hormone. Endocrinology 104:765-773
5. 5. Leung PC, Steele GL 1992 Intracellular signaling in the gonads. Endocr Rev 13:476-498
6. 6. Liu G, Duranteau L, Carol JC, Monroe J, Doyle DD, Shenker A 1999 Leydig cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor. N Engl J Med 341:1731-1734
7. 7. Gerard RD, Meidell RS 1994 Adenovirus vectors. In: Rickwood D, Hames BD (eds) DNA Cloning 4: A Practical Approach, Ed 2. Oxford University Press, Oxford, pp 285-306
8. 8. Graham FL, Smiley J, Russell WC, Nairn R 1977 Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 36:59-72
9. 9. Mittereder N, March L, Trapnell BC 1996 Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J Virol 70:7498-7509
10. 10. Hunter WM, Greenwood FC 1962 Preparation of iodine-131 labeled growth hormone of high specific activity. Nature 194:495-496
11. 11. Hickey GJ, Krasnow JS, Bealtie WG, Richards JS 1990 Aromatase cytochrome P450 in rat ovarian granulosa cells before and after luteinization: adenosine 3′,5′-monophosphate-dependent and independent regulation. Cloning and sequencing of rat aromatase cDNA and 5′ genomic DNA. Mol Endocrinol 4:3-12
12. 12. McFarland KC, Sprengel R, Phillips HS, Kohler M, Rosemblit N, Nikolics K, Segaloff DL, Seeburg PH 1989 Lutropin-choriogonadotropin receptor: an unusual member of the G protein-coupled receptor family. Science 245:494-499
13. 13. Esch FS, Shimasaki S, Cooksey K, Mercado M, Mason AJ, Ying SY, Ueno N, Ling N 1997 Complementary deoxyribonucleic acid (cDNA) cloning and DNA sequence analysis of rat ovarian inhibins. Mol Endocrinol 1:388-396
14. 5-4-isomerase expression in rat and characterization of the testis isoform. Mol Cell Endocrinol: 80:21-31
15. 15. Danielson PE, Forss-Petter S, Brow MA, Calavetta L, Douglass J, Milner RJ, Sutcliffe JG 1998 p1B15: a cDNA clone of the rat mRNA encoding cyclophilin. DNA 7:261-267
16. 16. Zeleznik AJ, Resko JA 1980 Progesterone does not inhibit gonadotropin-induced follicular maturation in the female rhesus monkey. Endocrinology 106:1820-1826
17. 17. Steiner AL, Parker CW, Kipnis DM 1972 Radioimmunoassay for cyclic nucleotides. I. Preparation of antibodies and iodinated cyclic nucleotides. J Biol Chem 247:1106-1113
18. 18. Zeleznik AJ, Midgley Jr AR, Reichert Jr LE 1974 Granulosa cell maturation in the rat: increased binding of human chorionic gonadotropin following treatment with follicle stimulating hormone in vivo. Endocrinology 95:818-825
19. 19. Erickson GF, Hsueh AJ 1978 Stimulation of aromatase activity by follicle stimulating hormone in rat granulosa cells in vivo and in vitro. Endocrinology 102:1275-1282
20. 20. Hickey GJ, Chen SA, Besman MJ, Shively JE, Hall PF, Gaddy-Kurten D, Richards JS 1988 Hormonal regulation, tissue distribution, and content of aromatase cytochrome P450 messenger ribonucleic acid and enzyme in rat ovarian follicles and corpora lutea: relationship to estradiol biosynthesis. Endocrinology 122:1426-1436
21. 21. Segaloff DL, Wang HY, Richards JS 1990 Hormonal regulation of luteinizing hormone/chorionic gonadotropin receptor mRNA in rat ovarian cells during follicular development and luteinization. Mol Endocrinol 4:1856-1865
22. 22. Yong EL, Hillier SG, Turner M, Baird DT, Ng SC, Bongso A, Ratnam SS 1994 Differential regulation of cholesterol side-chain cleavage (P450scc) and aromatase (P450arom) enzyme mRNA expression by gonadotropins and cyclic AMP in human granulosa cells. J Mol Endocrinol 12:239-249
23. 23. Silverman E, Eimerl S, Orly J 1999 CCAAT enhancer-binding protein beta and GATA-4 binding regions within the promoter of the steroidogenic acute regulatory protein (StAR) gene are required for transcription in rat ovarian cells. J Biol Chem 274:17987-17996
24. 24. Ratoosh SL, Lifka J, Hedin L, Jahsen T, Richards JS 1987 Hormonal regulation of the synthesis and mRNA content of the regulatory subunit of cyclic AMP-dependent protein kinase type II in cultured rat ovarian granulosa cells. J Biol Chem 262:7306-7313
25. 25. Carr DW, Cutler Jr RE, Cottom JE, Salvador LM, Fraser IDC, Scott JD, Hunzicker-Dunn M 1999 Identification of cAMP-dependent protein kinase holoenzymes in preantral and preovulatory follicle enriched ovaries, and their association with A-kinase anchoring proteins. Biochem J 344:613-623
26. 26. Somers JP, DeLoia JA, Zeleznik AJ 1999 Adenovirus-directed expression of a nonphosphorylatable mutant of CREB (cAMP response element-binding protein) adversely affects the survival, but not the differentiation, of rat granulosa cells. Mol Endocrinol 13:1364-1372
27. 27. Welsh Jr TH, Jia XC, Hsueh AJ 1984 Forskolin and phosphodiesterase inhibitors stimulate rat granulosa cell differentiation. Mol Cell Endocrinol 37:51-60
28. 28. Davoren JB, Hsueh AJ 1985 Vasoactive intestinal peptide: a novel stimulator of steroidogenesis by cultured rat granulosa cells. Biol Reprod 33:37-52
29. 29. Piquette GN, LaPolt PS, Oikawa M, Hsueh AJ 1991 Regulation of luteinizing hormone receptor messenger ribonucleic acid levels by gonadotropins, growth factors, and gonadotropin-releasing hormone in cultured rat granulosa cells. Endocrinology 128:2449-2456
30. 30. Sullivan MW, Stewart-Akers A, Krasnow JS, Berga SL, Zeleznik AJ 1999 Ovarian responses in women to recombinant follicle-stimulating hormone and luteinizing hormone (LH): a role for LH in the final stages of follicular maturation. J Clin Endocrinol Metab 84:228-232
31. 31. Campbell BK, Dobson H, Baird DT, Scaramuzzi RJ 1999 Examination of the relative role of FSH and LH in the mechanism of ovulatory follicle selection in sheep. J Reprod Fertil 117:355-367
32. 32. Tapainen JS, Lapolt PS, Perlas E, Hsueh AJ 1993 Induction of ovarian follicle luteinization by recombinant follicle-stimulating hormone. Endocrinology 133:2875-2880
33. 2+ in isolated bovine luteal cells. J Biol Chem 262:8515-8521
34. 34. Flores JA, Leong DA, Veldhuis JD 1992 Is the calcium signal induced by follicle-stimulating hormone in swine granulosa cells mediated by adenosine cyclic3′,5′-monophosphate-dependent protein kinase? Endocrinology 130:1862-1866
35. 35. Cameron MR, Foster JS, Bukovsky A, Wimalasena J 1996 Activation of mitogen-activated kinases by gonadotropins and cyclic adenosine 5′-monophosphates in porcine granulosa cells. Biol Reprod 55:111-119
36. 36. Das S, Maizels ET, DeManno D, St Clair E, Adam SA, Hunzicker-Dunn M 1996 A stimulatory role of cyclic adenosine 3′,5′-monophosphate in follicle-stimulating hormone-activated mitogen-activated protein kinase signaling pathway in rat ovarian granulosa cells. Endocrinology 137:967-974
37. 37. Shimamoto T, Yamoto M, Nakano R 1998 The role of tyrosine kinase in gonadotropin-induced ovulation in the rat ovary. Eur J Endocrinol 138:594-600
38. 38. Orly J, Rei Z, Greenberg NM, Richards JS 1994 Tyrosine kinase inhibitor AG18 arrests follicle-stimulating hormone-induced granulosa cell differentiation: use of reverse transcriptase-polymerase chain reaction assay for multiple messenger ribonucleic acids. Endocrinology 134:2336-2346
39. 39. Gonzalez-Robayna IJ, Falender AE, Ochsner S, Firestone GL, Richards JS 2000 Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-Induced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells. Mol Endocrinol 14:1283-1300
40. 40. Babu PS, Krishnamurthy H, Chedrese PJ, Sairam MR 2000 Activation of extracellular-regulated kinase pathways in ovarian granulosa cells by the novel growth factor type 1 follicle-stimulating hormone receptor. Role in hormone signaling and cell proliferation. J Biol Chem 275:27615-2726
41. 41. Davis JS, Weakland LL, West LA, Farese RV 1986 Luteinizing hormone stimulates the formation of inositol trisphosphate and cyclic AMP in rat granulosa cells. Evidence for phospholipase C generated second messengers in the action of luteinizing hormone. Biochem J 238:597-604
42. 2+ mobilization. J Biol Chem 267:4479-4488
43. 12. Biochemistry 38:12490-12498
44. 44. Shinohara O, Knecht M, Catt KJ 1985 Inhibition of gonadotropin-induced granulosa cell differentiation by activation of protein kinase C. Proc Natl Acad Sci USA 82:8518-8522