Induction of apoptosis by staurosporine involves the inhibition of expression of the major cell cycle proteins at the G2/M checkpoint accompanied by alterations in Erk and Akt kinase activities

Anticancer Research

Volumn 29, Issue 8, 2009, Pages 2893-2898

  Antonsson, Andreas ^a   Persson, Jenny L ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Apoptosis; Caspase 3; Cell cycle regulatory proteins; Leukemic cells; Staurosporine

Indexed keywords

CASPASE 3; CYCLIN A2; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE; PROCASPASE 3; PROTEIN KINASE B; PROTEIN KINASE B BETA; PROTEIN P21; PROTEIN P27; SERINE; STAUROSPORINE; THREONINE;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER CONTROL; CANCER SURVIVAL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRAIN U937; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; TREATMENT RESPONSE;

APOPTOSIS; CELL CYCLE PROTEINS; CELL DIVISION; CELL PROLIFERATION; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; G2 PHASE; HUMANS; IMMUNOBLOTTING; PHOSPHORYLATION; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; STAUROSPORINE; U937 CELLS;

EID: 68549112851     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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