Microfluidic flow fractionation device for label-free isolation of circulating tumor cells (CTCs) from breast cancer patients

Biosensors and Bioelectronics

Volumn 40, Issue 1, 2013, Pages 206-212

  Hyun, Kyung A ^a   Kwon, Kiho ^a   Han, Hyunju ^a   Kim, Seung Il ^a   Jung, Hyo Il ^a  

^a Yonsei University   (South Korea)

Author keywords

Breast cancer; Circulating tumor cell; Flow fractionation; Metastasis

Indexed keywords

BLOOD SAMPLES; BREAST CANCER; CANCER PROGNOSIS; CELL SIZE; CIRCULATING TUMOR CELLS; FRACTIONATION DEVICES; HYDRODYNAMIC FORCES; LABEL FREE; METASTASIS; MICROFLUIDIC FLOW; PERIPHERAL BLOOD; WHOLE BLOOD;

BLOOD; DIAGNOSIS; MICROFLUIDICS; PATHOLOGY;

DISEASES;

ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; BREAST CANCER; CELL COUNT; CELL ISOLATION; CELL SIZE; CIRCULATING TUMOR CELL; EQUIPMENT DESIGN; HUMAN; HUMAN CELL; HYDRODYNAMICS; LABORATORY DEVICE; MICROFLUIDIC ANALYSIS; PARALLEL MULTI ORIFICE FLOW FRACTIONATION DEVICE;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SEPARATION; CHEMICAL FRACTIONATION; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FLOW CYTOMETRY; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; NEOPLASTIC CELLS, CIRCULATING;

EID: 84868659815     PISSN: 09565663     EISSN: 18734235     Source Type: Journal    
DOI: 10.1016/j.bios.2012.07.021     Document Type: Article

References (17)

1. Chen C.L., Chen K.C., Pan Y.C., Lee T.P., Hsiung L.C., Lin C.M., Chen C.Y., Lin C.H., Chiang B.L., Wo A.M. Lab on a Chip-Miniaturisation for Chemistry and Biology 2011, 11(3):474-483.
2. Cristofanilli M., Hayes D.F., Budd G.T., Ellis M.J., Stopeck A., Reuben J.M., Doyle G.V., Matera J., Allard W.J., Miller M.C., Fritsche H.A., Hortobagyi G.N., Terstappen L.W.M.M. Journal of Clinical Oncology 2005, 23(7):1420-1430.
3. den Toonder J. Lab on a Chip 2011, 11(3):375-377.
4. Han K.H., Han A., Frazier A.B. Biosensors and Bioelectronics 2006, 21(10):1907-1914.
5. Hou J.M., Krebs M., Ward T., Morris K., Sloane R., Blackhall F., Dive C. Cancers 2010, 2(2):1236-1250.
6. Hsieh H.B., Marrinucci D., Bethel K., Curry D.N., Humphrey M., Krivacic R.T., Kroener J., Kroener L., Ladanyi A., Lazarus N., Kuhn P., Bruce R.H., Nieva J. Biosensors and Bioelectronics 2006, 21(10):1893-1899.
7. Kim S.I., Jung H.I. Journal of Breast Cancer 2010, 13(2):125-131.
8. Moon H.S., Kwon K., Kim S.I., Han H., Sohn J., Lee S., Jung H.I. Lab on a Chip 2011, 11(6):1118-1125.
9. Nagrath S., Sequist L.V., Maheswaran S., Bell D.W., Irimia D., Ulkus L., Smith M.R., Kwak E.L., Digumarthy S., Muzikansky A., Ryan P., Balis U.J., Tompkins R.G., Haber D.A., Toner M. Nature 2007, 450(7173):1235-1239.
10. Park J.S., Song S.H., Jung H.I. Lab on a Chip-Miniaturisation for Chemistry and Biology 2009, 9(7):939-948.
11. Park J.S., Jung H.I. Analytical Chemistry 2009, 81(20):8280-8288.
12. Prang N., Preithner S., Brischwein K., Göster P., Wöppel A., Müller J., Steiger C., Peters M., Baeuerle P.A., Da Silva A.J. British Journal of Cancer 2005, 92(2):342-349.
13. Sim T.S., Kwon K., Park J.C., Lee J.G., Jung H.I. Lab on a Chip-Miniaturisation for Chemistry and Biology 2011, 11(1):93-99.
14. Stott S.L., Hsu C.H., Tsukrov D.I., Yu M., Miyamoto D.T., Waltman B.A., Michael Rothenberg S., Shah A.M., Smas M.E., Korir G.K., Floyd F.P., Gilman A.J., Lord J.B., Winokur D., Springer S., Irimia D., Nagrath S., Sequist L.V., Lee R.J., Isselbacher K.J., Maheswaran S., Haber D.A., Toner M. Proceedings of the National academy of Sciences of the United States of America 2010, 107(43):18392-18397.
15. Van De Stolpe A., Pantel K., Sleijfer S., Terstappen L.W., Den Toonder J.M.J. Cancer Research 2011, 71(18):5955-5960.
16. Vona G., Sabile A., Louha M., Sitruk V., Romana S., Schutze K., Capron F., Franco D., Pazzagli M., Vekemans M., Lacour B., Brechot C., Paterlini-Brechot P. American Journal of Pathology 2000, 156(1):57-63.
17. Zhe X., Cher M.L., Bonfil R.D. American Journal of Cancer Research 2011, 1(6):740-751.