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Volumn 12, Issue 1, 2014, Pages 177-186
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Diverse modifications of the 4-methylphenyl moiety of TAK-779 by late-stage Suzuki-Miyaura cross-coupling
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Author keywords
[No Author keywords available]
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Indexed keywords
BINDING ENERGY;
BIOCHEMISTRY;
BINDING AFFINITIES;
BUILDING BLOCKES;
CHEMOKINE RECEPTORS;
ORAL BIOAVAILABILITIES;
QUATERNARY AMMONIUM;
SUZUKI-MIYAURA CROSS-COUPLING;
SUZUKI-MIYAURA CROSS-COUPLING REACTION;
SYNTHETIC STRATEGIES;
CHEMICAL REACTIONS;
HUMAN IMMUNODEFICIENCY VIRUS;
HUMAN IMMUNODEFICIENCY VIRUS 1;
AMIDE;
CHEMOKINE RECEPTOR CCR5;
N [4 [[[6,7 DIHYDRO 2 (4 METHYLPHENYL) 5H BENZOCYCLOHEPTEN 8 YL]CARBONYL]AMINO]BENZYL] N,N DIMETHYL 2H TETRAHYDROPYRAN 4 AMINIUM CHLORIDE;
QUATERNARY AMMONIUM DERIVATIVE;
ARTICLE;
CHEMICAL STRUCTURE;
CHEMISTRY;
DOSE RESPONSE;
DRUG ANTAGONISM;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
AMIDES;
DOSE-RESPONSE RELATIONSHIP, DRUG;
MOLECULAR STRUCTURE;
QUATERNARY AMMONIUM COMPOUNDS;
RECEPTORS, CCR5;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 84889050828
PISSN: 14770520
EISSN: None
Source Type: Journal
DOI: 10.1039/c3ob41873a Document Type: Article |
Times cited : (9)
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References (21)
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