Association of CCR5 Δ32 with reduced risk of asthma

Lancet

Volumn 354, Issue 9186, 1999, Pages 1264-1265

  Hall, Ian P ^a   Wheatley, Amanda ^a   Christie, Gordon ^a   McDougall, Catherine ^a   Hubbard, Richard ^a   Helms, Peter J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; DNA; CHEMOKINE RECEPTOR CCR5;

ADOLESCENT; ALLELE; ARTICLE; ASTHMA; CHILD; DELETION MUTANT; DNA SEQUENCE; GENE MUTATION; GENETIC DRIFT; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MONOCYTE; PREVALENCE; PRIORITY JOURNAL; RISK; GENE FREQUENCY; GENETICS; LETTER; PRESCHOOL CHILD; UNITED KINGDOM;

ADOLESCENT; ALLELES; ASTHMA; CHILD; CHILD, PRESCHOOL; GENE FREQUENCY; GENOTYPE; HUMANS; PREVALENCE; RECEPTORS, CCR5; SCOTLAND;

EID: 0033539191     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(99)03425-X     Document Type: Article

References (5)

1. Baggiolini M. Chemokines and leukocyte traffic. Nature. 392:1998;565-568.
2. Lukacs N.W.et al. Differential recruitment of leukocyte populations and alteration of airway hyperreactivity by C-C family chemokines in allergic airway inflammation. J Immunol. 158:1997;4398-4404.
3. Dean M.et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Science. 273:1996;1856-1862.
4. Samson M. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR5 chemokine receptor gene. Nature. 382:1996;722.
5. 2 adrenoceptor polymorphism with reported childhood asthma. BMJ. 316:1998;664.