Selection of peptide inhibitors for double-stranded RNA-dependent protein kinase PKR

Biochemistry (Moscow)

Volumn 78, Issue 11, 2013, Pages 1254-1262

  Du, M J ^a   Zhang, H K ^b   He, A J ^c   Chang, Y S ^a   Yang, Y ^a   Wang, Y ^a   Zhang, C Z ^a   Cao, Y ^a  

^a NANKAI UNIVERSITY   (China)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c Tianjin Second Business College   (China)

Author keywords

fragment based docking; kinase inhibitors; peptides; phage display; PKR

Indexed keywords

EUKARYOTA;

INITIATION FACTOR 2; PEPTIDE; PROTEIN KINASE INHIBITOR; PROTEIN KINASE R; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BIOSYNTHESIS; CELL SURFACE DISPLAY; CHEMISTRY; DRUG ANTAGONISM; GENETICS; HELA CELL LINE; HUMAN; METABOLISM; MOLECULAR DOCKING; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; CELL SURFACE DISPLAY TECHNIQUES; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; HELA CELLS; HUMANS; MOLECULAR DOCKING SIMULATION; PEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 84889050795     PISSN: 00062979     EISSN: 16083040     Source Type: Journal    
DOI: 10.1134/S0006297913110059     Document Type: Article

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