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Volumn 34, Issue 12, 2013, Pages 2778-2788

JWA inhibits melanoma angiogenesis by suppressing ILK signaling and is an independent prognostic biomarker for melanoma

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; INTEGRIN LINKED KINASE; JWA PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

EID: 84889039757     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgt318     Document Type: Article
Times cited : (24)

References (49)
  • 1
    • 84872967522 scopus 로고    scopus 로고
    • Cancer statistics, 2013
    • Siegel,R. et al. (2013) Cancer statistics, 2013. CA. Cancer J. Clin., 63, 11-30.
    • (2013) CA. Cancer J. Clin. , vol.63 , pp. 11-30
    • Siegel, R.1
  • 2
    • 0036780566 scopus 로고    scopus 로고
    • Focus on melanoma
    • Houghton,A.N. et al. (2002) Focus on melanoma. Cancer Cell, 2, 275-278.
    • (2002) Cancer Cell , vol.2 , pp. 275-278
    • Houghton, A.N.1
  • 3
    • 0035881074 scopus 로고    scopus 로고
    • Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma
    • Balch,C.M. et al. (2001) Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J. Clin. Oncol., 19, 3635-3648.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3635-3648
    • Balch, C.M.1
  • 4
    • 57649170741 scopus 로고    scopus 로고
    • Current management of metastatic melanoma
    • Trinh,V.A. (2008) Current management of metastatic melanoma. Am. J. Health. Syst. Pharm., 65 (suppl. 9), S3-S8.
    • (2008) Am. J. Health. Syst. Pharm. , vol.65 , Issue.SUPPL. 9
    • Trinh, V.A.1
  • 5
    • 84856029642 scopus 로고    scopus 로고
    • A new era in the treatment of melanoma: from biology to clinical practice
    • Árquez-Rodas,I. et al. (2011) A new era in the treatment of melanoma: from biology to clinical practice. Clin. Transl. Oncol., 13, 787-792.
    • (2011) Clin. Transl. Oncol. , vol.13 , pp. 787-792
    • Árquez-Rodas, I.1
  • 6
    • 84858376938 scopus 로고    scopus 로고
    • Opportunities and challenges in tumor angiogenesis research: back and forth between bench and bed
    • Qin,L. et al. (2012) Opportunities and challenges in tumor angiogenesis research: back and forth between bench and bed. Adv. Cancer Res., 113, 191-239.
    • (2012) Adv. Cancer Res. , vol.113 , pp. 191-239
    • Qin, L.1
  • 7
    • 81255188940 scopus 로고    scopus 로고
    • Tumor angiogenesis: molecular pathways and therapeutic targets
    • Weis,S.M. et al. (2011) Tumor angiogenesis: molecular pathways and therapeutic targets. Nat. Med., 17, 1359-1370.
    • (2011) Nat. Med. , vol.17 , pp. 1359-1370
    • Weis, S.M.1
  • 9
    • 0037067238 scopus 로고    scopus 로고
    • Molecular cloning, gene structure, expression profile and functional characterization of the mouse glutamate transporter (EAAT3) interacting protein GTRAP3-18
    • Butchbach,M.E. et al. (2002) Molecular cloning, gene structure, expression profile and functional characterization of the mouse glutamate transporter (EAAT3) interacting protein GTRAP3-18. Gene, 292, 81-90.
    • (2002) Gene , vol.292 , pp. 81-90
    • Butchbach, M.E.1
  • 10
    • 14844327521 scopus 로고    scopus 로고
    • JM4 is a four-transmembrane protein binding to the CCR5 receptor
    • Schweneker,M. et al. (2005) JM4 is a four-transmembrane protein binding to the CCR5 receptor. FEBS Lett., 579, 1751-1758.
    • (2005) FEBS Lett. , vol.579 , pp. 1751-1758
    • Schweneker, M.1
  • 11
    • 34147097435 scopus 로고    scopus 로고
    • JWA as a functional molecule to regulate cancer cells migration via MAPK cascades and F-actin cytoskeleton
    • Chen,H. et al. (2007) JWA as a functional molecule to regulate cancer cells migration via MAPK cascades and F-actin cytoskeleton. Cell. Signal, 19, 1315-1327.
    • (2007) Cell. Signal , vol.19 , pp. 1315-1327
    • Chen, H.1
  • 12
    • 77649190769 scopus 로고    scopus 로고
    • JWA regulates melanoma metastasis by integrin alphaVbeta3 signaling
    • Bai,J. et al. (2010) JWA regulates melanoma metastasis by integrin alphaVbeta3 signaling. Oncogene, 29, 1227-1237.
    • (2010) Oncogene , vol.29 , pp. 1227-1237
    • Bai, J.1
  • 13
    • 77349113764 scopus 로고    scopus 로고
    • Important role of integrins in the cancer biology
    • Rathinam,R. et al. (2010) Important role of integrins in the cancer biology. Cancer Metastasis Rev., 29, 223-237.
    • (2010) Cancer Metastasis Rev. , vol.29 , pp. 223-237
    • Rathinam, R.1
  • 14
    • 11144225205 scopus 로고    scopus 로고
    • Integrin-linked kinase: a cancer therapeutic target unique among its ILK
    • Hannigan,G. et al. (2005) Integrin-linked kinase: a cancer therapeutic target unique among its ILK. Nat. Rev. Cancer, 5, 51-63.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 51-63
    • Hannigan, G.1
  • 15
    • 33644848599 scopus 로고    scopus 로고
    • ILK, PINCH and parvin: the tIPP of integrin signalling
    • Legate,K.R. et al. (2006) ILK, PINCH and parvin: the tIPP of integrin signalling. Nat. Rev. Mol. Cell Biol., 7, 20-31.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 20-31
    • Legate, K.R.1
  • 16
    • 47749087950 scopus 로고    scopus 로고
    • Integrin-linked kinase-essential roles in physiology and cancer biology
    • McDonald,P.C. et al. (2008) Integrin-linked kinase-essential roles in physiology and cancer biology. J. Cell Sci., 121(Pt 19), 3121-3132.
    • (2008) J. Cell Sci. , vol.121 , Issue.PART 19 , pp. 3121-3132
    • McDonald, P.C.1
  • 17
    • 13144302939 scopus 로고    scopus 로고
    • Increased expression of integrin-linked kinase is associated with shorter survival in non-small cell lung cancer
    • Takanami,I. (2005) Increased expression of integrin-linked kinase is associated with shorter survival in non-small cell lung cancer. BMC Cancer, 5, 1.
    • (2005) BMC Cancer , vol.5 , pp. 1
    • Takanami, I.1
  • 18
    • 0034782943 scopus 로고    scopus 로고
    • Integrin-linked kinase expression increases with prostate tumor grade
    • Graff,J.R. et al. (2001) Integrin-linked kinase expression increases with prostate tumor grade. Clin. Cancer Res., 7, 1987-1991.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1987-1991
    • Graff, J.R.1
  • 19
    • 0141891463 scopus 로고    scopus 로고
    • Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival
    • Dai,D.L. et al. (2003) Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival. Clin. Cancer Res., 9, 4409-4414.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 4409-4414
    • Dai, D.L.1
  • 20
    • 79958789624 scopus 로고    scopus 로고
    • Integrin-linked kinase regulates melanoma angiogenesis by activating NF-κB/interleukin-6 signaling pathway
    • Wani,A.A. et al. (2011) Integrin-linked kinase regulates melanoma angiogenesis by activating NF-κB/interleukin-6 signaling pathway. Oncogene, 30, 2778-2788.
    • (2011) Oncogene , vol.30 , pp. 2778-2788
    • Wani, A.A.1
  • 21
    • 0037012729 scopus 로고    scopus 로고
    • Promoter characterization and genomic organization of the gene encoding integrin-linked kinase 1
    • Melchior,C. et al. (2002) Promoter characterization and genomic organization of the gene encoding integrin-linked kinase 1. Biochim. Biophys. Acta, 1575, 117-122.
    • (2002) Biochim. Biophys. Acta , vol.1575 , pp. 117-122
    • Melchior, C.1
  • 22
    • 67649304830 scopus 로고    scopus 로고
    • Integrin alphavbeta3 upregulates integrin-linked kinase expression in human ovarian cancer cells via enhancement of ILK gene transcription
    • Lössner,D. et al. (2009) Integrin alphavbeta3 upregulates integrin-linked kinase expression in human ovarian cancer cells via enhancement of ILK gene transcription. J. Cell. Physiol., 220, 367-375.
    • (2009) J. Cell. Physiol. , vol.220 , pp. 367-375
    • Lössner, D.1
  • 23
    • 58249089041 scopus 로고    scopus 로고
    • Nuclear factor kappa B subunit p50 promotes melanoma angiogenesis by upregulating interleukin-6 expression
    • Karst,A.M. et al. (2009) Nuclear factor kappa B subunit p50 promotes melanoma angiogenesis by upregulating interleukin-6 expression. Int. J. Cancer, 124, 494-501.
    • (2009) Int. J. Cancer , vol.124 , pp. 494-501
    • Karst, A.M.1
  • 24
    • 78650319117 scopus 로고    scopus 로고
    • Cell cycle regulator ING4 is a suppressor of melanoma angiogenesis that is regulated by the metastasis suppressor BRMS1
    • Li,J. et al. (2010) Cell cycle regulator ING4 is a suppressor of melanoma angiogenesis that is regulated by the metastasis suppressor BRMS1. Cancer Res., 70, 10445-10453.
    • (2010) Cancer Res. , vol.70 , pp. 10445-10453
    • Li, J.1
  • 25
    • 78650198694 scopus 로고    scopus 로고
    • Prognostic significance of Sox4 expression in human cutaneous melanoma and its role in cell migration and invasion
    • Jafarnejad,S.M. et al. (2010) Prognostic significance of Sox4 expression in human cutaneous melanoma and its role in cell migration and invasion. Am. J. Pathol., 177, 2741-2752.
    • (2010) Am. J. Pathol. , vol.177 , pp. 2741-2752
    • Jafarnejad, S.M.1
  • 26
    • 34250774522 scopus 로고    scopus 로고
    • The role of integrin-linked kinase in melanoma cell migration, invasion, and tumor growth
    • Wong,R.P. et al. (2007) The role of integrin-linked kinase in melanoma cell migration, invasion, and tumor growth. Mol. Cancer Ther., 6, 1692-1700.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 1692-1700
    • Wong, R.P.1
  • 27
    • 85013312416 scopus 로고
    • Tumor angiogenesis: therapeutic implications
    • Folkman,J. (1971) Tumor angiogenesis: therapeutic implications. N. Engl. J. Med., 285, 1182-1186.
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 28
    • 36849078591 scopus 로고    scopus 로고
    • Angiogenesis in melanoma
    • Mahabeleshwar,G.H. et al. (2007) Angiogenesis in melanoma. Semin. Oncol., 34, 555-565.
    • (2007) Semin. Oncol. , vol.34 , pp. 555-565
    • Mahabeleshwar, G.H.1
  • 29
    • 0031004936 scopus 로고    scopus 로고
    • Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes
    • Kok,K. et al. (1997) Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes. Adv. Cancer Res., 71, 27-92.
    • (1997) Adv. Cancer Res. , vol.71 , pp. 27-92
    • Kok, K.1
  • 30
    • 77953477155 scopus 로고    scopus 로고
    • Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer
    • Pontier,S.M. et al. (2010) Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer. Oncogene, 29, 3374-3385.
    • (2010) Oncogene , vol.29 , pp. 3374-3385
    • Pontier, S.M.1
  • 31
    • 9144270454 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by integrin-linked kinase (ILK)
    • Tan,C. et al. (2004) Regulation of tumor angiogenesis by integrin-linked kinase (ILK). Cancer Cell, 5, 79-90.
    • (2004) Cancer Cell , vol.5 , pp. 79-90
    • Tan, C.1
  • 32
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • Brooks,P.C. et al. (1994) Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science, 264, 569-571.
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1
  • 33
    • 0028670833 scopus 로고
    • Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks,P.C. et al. (1994) Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell, 79, 1157-1164.
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1
  • 35
    • 70350574674 scopus 로고    scopus 로고
    • An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression
    • Desgrosellier,J.S. et al. (2009) An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nat. Med., 15, 1163-1169.
    • (2009) Nat. Med. , vol.15 , pp. 1163-1169
    • Desgrosellier, J.S.1
  • 36
    • 27544439766 scopus 로고    scopus 로고
    • Sp transcription factor family and its role in cancer
    • Safe,S. et al. (2005) Sp transcription factor family and its role in cancer. Eur. J. Cancer, 41, 2438-2448.
    • (2005) Eur. J. Cancer , vol.41 , pp. 2438-2448
    • Safe, S.1
  • 37
    • 0348223971 scopus 로고    scopus 로고
    • Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer
    • Wang,L. et al. (2003) Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer. Clin. Cancer Res., 9, 6371-6380.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 6371-6380
    • Wang, L.1
  • 38
    • 80052829997 scopus 로고    scopus 로고
    • The impairment of ILK related angiogenesis involved in cardiac maladaptation after infarction
    • Xie,J. et al. (2011) The impairment of ILK related angiogenesis involved in cardiac maladaptation after infarction. PLoS One, 6, e24115.
    • (2011) PLoS One , vol.6
    • Xie, J.1
  • 39
    • 4444305175 scopus 로고    scopus 로고
    • Integrin-linked kinase regulates endothelial cell survival and vascular development
    • Friedrich,E.B. et al. (2004) Integrin-linked kinase regulates endothelial cell survival and vascular development. Mol. Cell. Biol., 24, 8134-8144.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 8134-8144
    • Friedrich, E.B.1
  • 40
    • 0034702253 scopus 로고    scopus 로고
    • Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation
    • Janji,B. et al. (2000) Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation. Oncogene, 19, 3069-3077.
    • (2000) Oncogene , vol.19 , pp. 3069-3077
    • Janji, B.1
  • 41
    • 33749032836 scopus 로고    scopus 로고
    • Prognostic significance of nuclear factor-kappaB p105/p50 in human melanoma and its role in cell migration
    • Gao,K. et al. (2006) Prognostic significance of nuclear factor-kappaB p105/p50 in human melanoma and its role in cell migration. Cancer Res., 66, 8382-8388.
    • (2006) Cancer Res. , vol.66 , pp. 8382-8388
    • Gao, K.1
  • 42
    • 0342646934 scopus 로고    scopus 로고
    • Autocrine and paracrine regulation by cytokines and growth factors in melanoma
    • Lázár-Molnár,E. et al. (2000) Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine, 12, 547-554.
    • (2000) Cytokine , vol.12 , pp. 547-554
    • Lázár-Molnár, E.1
  • 43
    • 0037435011 scopus 로고    scopus 로고
    • Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway
    • Wei,L.H. et al. (2003) Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway. Oncogene, 22, 1517-1527.
    • (2003) Oncogene , vol.22 , pp. 1517-1527
    • Wei, L.H.1
  • 44
    • 2642579084 scopus 로고    scopus 로고
    • Interleukin-6 increases vascular endothelial growth factor and angiogenesis in gastric carcinoma
    • Huang,S.P. et al. (2004) Interleukin-6 increases vascular endothelial growth factor and angiogenesis in gastric carcinoma. J. Biomed. Sci., 11, 517-527.
    • (2004) J. Biomed. Sci. , vol.11 , pp. 517-527
    • Huang, S.P.1
  • 45
    • 67650087998 scopus 로고    scopus 로고
    • Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness
    • Saidi,A. et al. (2009) Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness. Int. J. Cancer, 125, 1054-1064.
    • (2009) Int. J. Cancer , vol.125 , pp. 1054-1064
    • Saidi, A.1
  • 46
    • 41349099104 scopus 로고    scopus 로고
    • Cancer statistics, 2008
    • Jemal,A. et al. (2008) Cancer statistics, 2008. CA. Cancer J. Clin., 58, 71-96.
    • (2008) CA. Cancer J. Clin. , vol.58 , pp. 71-96
    • Jemal, A.1
  • 47
    • 84871955157 scopus 로고    scopus 로고
    • a-Catulin drives metastasis by activating ILK and driving an avß3 integrin signaling axis
    • Liang,C.H. et al. (2013) a-Catulin drives metastasis by activating ILK and driving an avß3 integrin signaling axis. Cancer Res., 73, 428-438.
    • (2013) Cancer Res. , vol.73 , pp. 428-438
    • Liang, C.H.1
  • 48
    • 62149130798 scopus 로고    scopus 로고
    • Combined inhibition of integrin linked kinase and FMS-like tyrosine kinase 3 is cytotoxic to acute myeloid leukemia progenitor cells
    • Muranyi,A.L. et al. (2009) Combined inhibition of integrin linked kinase and FMS-like tyrosine kinase 3 is cytotoxic to acute myeloid leukemia progenitor cells. Exp. Hematol., 37, 450-460.
    • (2009) Exp. Hematol. , vol.37 , pp. 450-460
    • Muranyi, A.L.1
  • 49
    • 77957363101 scopus 로고    scopus 로고
    • Integrins as therapeutic targets: lessons and opportunities
    • Cox,D. et al. (2010) Integrins as therapeutic targets: lessons and opportunities. Nat. Rev. Drug Discov., 9, 804-820.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 804-820
    • Cox, D.1


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