β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency

Cellular Signalling

Volumn 26, Issue 2, 2014, Pages 260-267

  Ring, Larisa ^a   Neth, Peter ^a   Weber, Christian ^a,b   Steffens, Sabine ^a,b   Faussner, Alexander ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

FZD; LRP5 6; WNT; WNT catenin signalling

Indexed keywords

BETA CATENIN; FRIZZLED PROTEIN; HYBRID PROTEIN; LIGAND; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; WNT3A PROTEIN; WNT4 PROTEIN; WNT5A PROTEIN;

ARTICLE; CONTROLLED STUDY; EMBRYO; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

FZD; LRP5/6; WNT; WNT/Β-CATENIN SIGNALLING;

BETA CATENIN; FRIZZLED RECEPTORS; GENES, REPORTER; HEK293 CELLS; HUMANS; LIGANDS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-5; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; PROTO-ONCOGENE PROTEINS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; WNT PROTEINS; WNT3A PROTEIN; WNT4 PROTEIN;

EID: 84889038596     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.11.021     Document Type: Article

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