Oncostatin M and TLR-4 ligand synergize to induce MCP-1, IL-6, and VEGF in human aortic adventitial fibroblasts and smooth muscle cells

Mediators of Inflammation

Volumn 2013, Issue , 2013, Pages

  Schnittker, David ^a   Kwofie, Karen ^a   Ashkar, Ali ^a   Trigatti, Bernardo ^b   Richards, Carl D ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 11; INTERLEUKIN 31; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; ONCOSTATIN M; ONCOSTATIN M RECEPTOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; STAT PROTEIN; TOLL LIKE RECEPTOR 4; VASCULOTROPIN; CCL2 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; LIGAND; TLR4 PROTEIN, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ADVENTITIA; AORTIC ADVENTITIAL FIBROBLAST; ARTICLE; ATHEROGENESIS; CELL LEVEL; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL STUDY; FIBROBLAST; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; STEADY STATE; SUPERNATANT; AORTA; ATHEROSCLEROSIS; CELL CULTURE; CYTOLOGY; GENE EXPRESSION REGULATION; INFLAMMATION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION;

ADVENTITIA; AORTA; ATHEROSCLEROSIS; CELLS, CULTURED; CHEMOKINE CCL2; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTERLEUKIN-11; INTERLEUKIN-6; INTERLEUKIN-8; LIGANDS; LIPOPOLYSACCHARIDES; MYOCYTES, SMOOTH MUSCLE; ONCOSTATIN M; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84889012741     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2013/317503     Document Type: Article

References (40)

1. Libby P., Inflammation in atherosclerosis. Nature 2002 420 6917 868 874 2-s2.0-0037180771 10.1038/nature01323
2. Shi Y., O'Brien J. E. Jr., Mannion J. D., Morrison R. C., Chung W., Fard A., Zalewski A., Remodeling of autologous saphenous vein grafts: the role of perivascular myofibroblasts. Circulation 1997 95 12 2684 2693 2-s2.0-0030997882
3. Scott N. A., Cipolla G. D., Ross C. E., Dunn B., Martin F. H., Simonet L., Wilcox J. N., Identification of a potential role for the adventitia in vascular lesion formation after balloon overstretch injury of porcine coronary arteries. Circulation 1996 93 12 2178 2187 2-s2.0-0029934015
4. Pagano P. J., Clark J. K., Cifuentes-Pagano M. E., Clark S. M., Callis G. M., Quinn M. T., Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: enhancement by angiotensin II. Proceedings of the National Academy of Sciences of the United States of America 1997 94 26 14483 14488 2-s2.0-0031443873 10.1073/pnas.94.26.14483
5. Li X. D., Chen J., Ruan C. C., Zhu D. L., Gao P. J., Vascular endothelial growth factor-induced osteopontin expression mediates vascular inflammation and neointima formation via Flt-1 in adventitial fibroblasts. Arteriosclerosis, Thrombosis, and Vascular Biology 2012 32 2250 2258 10.1161/ATVBAHA.112.255216
6. Tieu B. C., Lee C., Sun H., LeJeune W., Recinos A. III, Ju X., Spratt H., Guo D. C., Milewicz D., Tilton R. G., Brasier A. R., An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice. Journal of Clinical Investigation 2009 119 12 3637 3651 2-s2.0-72849142816 10.1172/JCI38308
7. Gu L., Okada Y., Clinton S. K., Gerard C., Sukhova G. K., Libby P., Rollins B. J., Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Molecular Cell 1998 2 2 275 281 2-s2.0-0032134003
8. Huber S. A., Sakkinen P., Conze D., Hardin N., Tracy R., Interleukin-6 exacerbates early atherosclerosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology 1999 19 10 2364 2367 2-s2.0-0032856199
9. Celletti F. L., Waugh J. M., Amabile P. G., Brendolan A., Hilfiker P. R., Dake M. D., Vascular endothelial growth factor enhances atherosclerotic plaque progression. Nature Medicine 2001 7 4 425 429 2-s2.0-0035047885 10.1038/86490
10. Gerszten R. E., Garcia-Zepeda E. A., Lim Y. C., Yoshida M., Ding H. A., Gimbrone M. A. Jr., Luster A. D., Luscinskas F. W., Rosenzwelg A., MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature 1999 398 6729 718 725 2-s2.0-0033594416 10.1038/19546
11. Demyanets S., Huber K., Wojta J., Vascular effects of glycoprotein130 ligands. Part I: pathophysiological role. Vascular Pharmacology 2012 56 1-2 34 46 2-s2.0-84856258312 10.1016/j.vph.2011.12.004
12. Albasanz-Puig A., Murray J., Preusch M., Coan D., Namekata M., Patel Y., Dong Z. M., Rosenfeld M. E., Wijelath E. S., Oncostatin M is expressed in atherosclerotic lesions: a role for Oncostatin M in the pathogenesis of atherosclerosis. Atherosclerosis 2011 216 2 292 298 2-s2.0-79957986058 10.1016/j.atherosclerosis.2011.02.003
13. Schieffer B., Schieffer E., Hilfiker-Kleiner D., Hilfiker A., Kovanen P. T., Kaartinen M., Nussberger J., Harringer W., Drexler H., Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability. Circulation 2000 101 12 1372 1378 2-s2.0-0034724305
14. Sukovich D. A., Kauser K., Shirley F. D., DelVecchio V., Halks-Miller M., Rubanyi G. M., Expression of interleukin-6 in atherosclerotic lesions of male apoE-knockout mice: inhibition by 17 β -estradiol. Arteriosclerosis, Thrombosis, and Vascular Biology 1998 18 9 1498 1505 2-s2.0-0031714562
15. Modur V., Feldhaus M. J., Weyrich A. S., Jicha D. L., Prescott S. M., Zimmerman G. A., McIntyre T. M., Oncostatin M is a proinflammatory mediator: in vivo effects correlate with endothelial cell expression of inflammatory cytokines and adhesion molecules. Journal of Clinical Investigation 1997 100 1 158 168 2-s2.0-0030757507
16. Romano M., Sironi M., Toniatti C., Polentarutti N., Fruscella P., Ghezzi P., Faggioni R., Luini W., van Hinsbergh V., Sozzani S., Bussolino F., Poli V., Ciliberto G., Mantovani A., Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity 1997 6 3 315 325 2-s2.0-0030891228 10.1016/S1074-7613(00)80334-9
17. Hui W., Cawston T., Rowan A. D., Transforming growth factor β 1 and insulin-like growth factor 1 block collagen degradation induced by oncostatin M in combination with tumour necrosis factor α from bovine cartilage. Annals of the Rheumatic Diseases 2003 62 2 172 174 2-s2.0-0037307962 10.1136/ard.62.2.172
18. Rowan A. D., Koshy P. J., Shingleton W. D., Degnan B. A., Heath J. K., Vernallis A. B., Spaull J. R., Life P. F., Hudson K., Cawston T. E., Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown. Arthritis & Rheumatism 2001 44 1620 1632 10.1002/1529-0131(200107)44:7<1620::AID-ART285>3.0.CO;2-B
19. Koshy P. J., Henderson N., Logan C., Life P. F., Cawston T. E., Rowan A. D., Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines. Annals of the Rheumatic Diseases 2002 61 8 704 713 2-s2.0-0035997484 10.1136/ard.61.8.704
20. Faffe D. S., Flynt L., Mellema M., Whitehead T. R., Bourgeois K., Panettieri R. A. Jr., Silverman E. S., Shore S. A., Oncostatin M causes VEGF release from human airway smooth muscle: synergy with IL-1 β American Journal of Physiology-Lung Cellular and Molecular Physiology 2005 288 6 L1040 L1048 2-s2.0-18844447702 10.1152/ajplung.00333.2004
21. den Dekker W. K., Cheng C., Pasterkamp G., Duckers H. J., Toll like receptor 4 in atherosclerosis and plaque destabilization. Atherosclerosis 2010 209 2 314 320 2-s2.0-77950020916 10.1016/j.atherosclerosis.2009.09.075
22. Michelsen K. S., Wong M. H., Shah P. K., Zhang W., Yano J., Doherty T. M., Akira S., Rajavashisth T. B., Arditi M., Lack of toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proceedings of the National Academy of Sciences of the United States of America 2004 101 29 10679 10684 2-s2.0-3242710174 10.1073/pnas.0403249101
23. Vink A., Schoneveld A. H., van der Meer J. J., van Middelaar B. J., Sluijter J. P. G., Smeets M. B., Quax P. H. A., Lim S. K., Borst C., Pasterkamp G., De Kleijn D. P. V., In vivo evidence for a role of toll-like receptor 4 in the development of intimal lesions. Circulation 2002 106 15 1985 1990 2-s2.0-0037044401 10.1161/01.CIR.0000032146.75113.EE
24. Fritz D. K., Kerr C., Tong L., Smyth D., Richards C. D., Oncostatin-M up-regulates VCAM-1 and synergizes with IL-4 in eotaxin expression: involvement of STAT6. Journal of Immunology 2006 176 7 4352 4360 2-s2.0-33646064471
25. Xu F., Ji J., Li L., Chen R., Hu W. C., Adventitial fibroblasts are activated in the early stages of atherosclerosis in the apolipoprotein E knockout mouse. Biochemical and Biophysical Research Communications 2007 352 3 681 688 2-s2.0-33845284257 10.1016/j.bbrc.2006.11.073
26. Ylä-Herttuala S., Lipton B. A., Rosenfeld M. E., Sarkioja T., Yoshimura T., Leonard E. J., Witztum J. L., Steinberg D., Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proceedings of the National Academy of Sciences of the United States of America 1991 88 12 5252 5256 2-s2.0-0025954705 10.1073/pnas.88.12.5252
27. Kuziel W. A., Morgan S. J., Dawson T. C., Griffin S., Smithies O., Ley K., Maeda N., Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proceedings of the National Academy of Sciences of the United States of America 1997 94 22 12053 12058 2-s2.0-0030691025 10.1073/pnas.94.22.12053
28. Klouche M., Bhakdi S., Hemmes M., Rose-John S., Novel path to activation of vascular smooth muscle cells: up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor. Journal of Immunology 1999 163 8 4583 4589 2-s2.0-0032846613
29. Inoue M., Itoh H., Ueda M., Naruko T., Kojima A., Komatsu R., Doi K., Ogawa Y., Tamura N., Takaya K., Igaki T., Yamashita J., Chun T. H., Masatsugu K., Becker A. E., Nakao K., Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions: possible pathophysiological significance of VEGF in progression of atherosclerosis. Circulation 1998 98 20 2108 2116 2-s2.0-0032542072
30. Soehnlein O., Multiple roles for neutrophils in atherosclerosis. Circulation Research 2012 110 6 875 888 2-s2.0-84858630089 10.1161/CIRCRESAHA. 111.257535
31. Richards C. D., Langdon C., Botelho F., Brown T. J., Agro A., Oncostatin M inhibits 1L-1-induced expression of IL-8 and granulocyte-macrophage colony-stimulating factor by synovial and lung fibroblasts. Journal of Immunology 1996 156 1 343 349 2-s2.0-0030029653
32. Hurst S. M., McLoughlin R. M., Monslow J., Owens S., Morgan L., Fuller G. M., Topley N., Jones S. A., Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. Journal of Immunology 2002 169 9 5244 5251 2-s2.0-0036838697
33. Raingeaud J., Pierre J., Interleukin-4 downregulates TNF α -induced IL-8 production in keratinocytes. FEBS Letters 2005 579 18 3953 3959 2-s2.0-21844437321 10.1016/j.febslet.2005.06.019
34. Goebeler M., Kilian K., Gillitzer R., Kunz M., Yoshimura T., Bröcker E. B., Rapp U. R., Ludwig S., The MKK6/p38 stress kinase cascade is critical for tumor necrosis factor- α -induced expression of monocyte- chemoattractant protein-1 in endothelial cells. Blood 1999 93 3 857 865 2-s2.0-0032936517
35. Kiriakidis S., Andreakos E., Monaco C., Foxwell B., Feldmann M., Paleolog E., VEGF expression in human macrophages is NF- B-dependent: studies using adenoviruses expressing the endogenous NF- B inhibitor I B α and a kinase-defective form of the I B kinase 2. Journal of Cell Science 2003 116 4 665 674 2-s2.0-0037442674 10.1242/jcs.00286
36. Riedemann N. C., Guo R. F., Hollmann T. J., Gao H., Neff T. A., Reuben J. S., Speyer C. L., Sarma J. V., Wetsel R. A., Zetoune F. S., Ward P. A., Regulatory role of C5a in LPS-induced IL-6 production by neutrophils during sepsis. The FASEB journal 2004 18 2 370 372 2-s2.0-1442290129
37. Hermanns H. M., Radtke S., Schaper F., Heinrich P. C., Behrmann I., Non-redundant signal transduction of interleukin-6-type cytokines: the adapter protein Shc is specifically recruited to the oncostatin M receptor. Journal of Biological Chemistry 2000 275 52 40742 40748 2-s2.0-0034731330 10.1074/jbc.M005408200
38. Lee J. D., Kato K., Tobias P. S., Kirkland T. N., Ulevitch R. J., Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein. Journal of Experimental Medicine 1992 175 6 1697 1705 2-s2.0-0026518709 10.1084/jem.175.6.1697
39. Faffe D. S., Flynt L., Mellema M., Moore P. E., Silverman E. S., Subramaniam V., Jones M. R., Mizgerd J. P., Whitehead T., Imrich A., Panettieri R. A. Jr., Shore S. A., Oncostatin M causes eotaxin-1 release from airway smooth muscle: synergy with IL-4 and IL-13. Journal of Allergy and Clinical Immunology 2005 115 3 514 520 2-s2.0-20044363972 10.1016/j.jaci.2004.11.033
40. Suda T., Chida K., Todate A., Ide K., Asada K., Nakamura Y., Suzuki K., Kuwata H., Nakamura H., Oncostatin M production by human dendritic cells in response to bacterial products. Cytokine 2002 17 6 335 340 2-s2.0-0035985395 10.1006/cyto.2002.1023