Comparative pathophysiology, toxicology, and human cancer risk assessment of pharmaceutical-induced hibernoma

Toxicology and Applied Pharmacology

Volumn 273, Issue 3, 2013, Pages 456-463

  Radi, Zaher ^a   Bartholomew, Phillip ^a   Elwell, Michael ^b   Vogel, W Mark ^a  

^a PFIZER INC   (United States)

^b Covance Laboratories ^*  (United States)

Author keywords

Brown adipose tissue; Carcinogenicity; Hibernoma; Human safety risk assessment; Pathobiology; Rat

Indexed keywords

HYDROMORPHONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHENTOLAMINE; TOFACITINIB; VARENICLINE;

ADRENERGIC STIMULATION; BROWN ADIPOSE TISSUE; CANCER RISK; CARCINOGENESIS; CELL ACTIVATION; CELL PROLIFERATION; COMPARATIVE STUDY; ERECTILE DYSFUNCTION; GENOTOXICITY; HIBERNOMA; HUMAN; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; RAT; REVIEW; RISK ASSESSMENT;

BROWN ADIPOSE TISSUE; CARCINOGENICITY; HIBERNOMA; HUMAN SAFETY RISK ASSESSMENT; PATHOBIOLOGY; RAT;

ANIMALS; BENZAZEPINES; CARCINOGENICITY TESTS; DISEASE MODELS, ANIMAL; HUMANS; HYDROMORPHONE; LIPOMA; MUTAGENICITY TESTS; NEOPLASMS; PHENTOLAMINE; PIPERIDINES; PYRIMIDINES; PYRROLES; QUINOXALINES; RATS; RISK ASSESSMENT;

RATTUS;

EID: 84888876910     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.10.011     Document Type: Review

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