Loss of heterozygosity at 11q13: Analysis of pituitary tumors, lung carcinoids, lipomas, and other uncommon tumors in subjects with familial multiple endocrine neoplasia type 1

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 5, 1997, Pages 1416-1420

  Dong, Qihan ^a,d   Debelenko, Larisa V ^a   Chandrasekharappa, Settara C ^c   Emmert Buck, Michael R ^b   Zhuang, Zhengping ^b   Guru, Siradanahalli C ^c   Manickam, Pachiappan ^c   Skarulis, Monica ^a   Lubensky, Irina A ^b   Liotta, Lance A ^b   Collins, Francis S ^c   Marx, Stephen J ^a   Spiegel, Allen M ^a,c  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CARCINOID; CHROMOSOME 11Q; CLINICAL ARTICLE; CLINICAL FEATURE; DNA POLYMORPHISM; FEMALE; HEMANGIOFIBROMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; HYPOPHYSIS ADENOMA; LIPOMA; LUNG TUMOR; MALE; MULTIPLE ENDOCRINE NEOPLASIA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROLACTINOMA; X CHROMOSOME INACTIVATION;

EID: 8244248448     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.82.5.3944     Document Type: Article

References (32)

1. Metz DC, Jensen RT, Bale AE, et al. 1994 Multiple endocrine neoplasia type I: clinical features and management. In: Bilezikian JP, Marcus R, Levine MA, eds. The parathyroids: basic and clinical concepts. New York: Raven Press; 591-646.
2. Darling TN, Skarulis MC, Steinberg SM, Marx SJ, Spiegel AM, Turner ML. 1997 Multiple facial angiofibromas and collagenomas in patients with multiple endocrine neoplasia type 1. Arch Derm. In press.
3. Larsson C, Skogseid B, Oberg K, Nakamura Y, Nordenskjold M. 1988 Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinomas. Nature. 332:85-87.
4. Bystrom C, Larsson C, Blomberg C, et al. 1990 Localization of the MEN 1 gene to a small region within chromosome 11q13 by deletion mapping in tumors. Proc Natl Acad Sci USA. 87:1968-1972.
5. Radford DM, Ashley SW, Wells Jr SA, Gerhard DS. 1990 Loss of heterozygosity of markers on chromosome 11 in tumors from patients with multiple endocrine neoplasia syndrome type 1. Cancer Res. 50:6529-6533.
6. Teh BT, Hayward NK, Wilkinson S, Woods GM, Cameron D, Shepherd JJ. 1990 Clonal loss of INT2 alleles in sporadic and familial pancreatic endocrine tumors. Br J Cancer. 62:253-254.
7. Bale AE, Norton JA, Wong EL, et al. 1991 Allelic loss on chromosome 11 in hereditary and sporadic tumors related to familial multiple endocrine neoplasia type 1. Cancer Res. 51:1154-1157.
8. Weber G, Friedman E, Grimmond S, et al. 1994 The phospholipase Cb3 gene located in the MEN1 region shows loss of expression in endocrine tumours. Hum Mol Genet. 3:1775-1781.
9. Thakker RV, Bouloux P, Wooding C, et al. 1989 Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles on chromosome 11. N Engl J Med. 321:218-224.
10. Friedman E, Sakaguchi K, Bale AE, et al. 1989 Clonality of parathyroid tumors in familial mutiple endocrine neoplasia type 1. N Engl J Med. 321:213-218.
11. Friedman E, De Marco L, Gejman PV, et al. 1992 Allelic loss from chromosome 11 in parathyroid tumors. Cancer Res. 52:6804-6809.
12. Beckers A, Abs R, Reyniers E, et al. 1994 Variable regions of chromosome 11 loss in different pathological tissues of a patient with the multiple endocrine neoplasia type 1 syndrome. J Clin Endocrinol Metab. 79:1498-1502.
13. Knudson Jr AG. 1971 Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA. 68:820-823.
14. s or thyrotropin-releasing hormone receptor genes. J Clin Endocrinol Metab. 81:1134-1140.
15. Lubensky IA, Debelenko LV, Zhuang Z, et al. 1996 Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN I patients. Cancer Res. 56:5272-5278.
16. Fina L. 1988 Expression of the CD34 gene in vascular endothelial cells. Blood. 75:2417-2426.
17. Larsson C, Calender A, Grimmond S, et al. 1995 Molecular tools for presymptomatic testing in multiple endocrine neoplasia type 1. J Intern Med. 238:234-244.
18. James MR, Richard CW, Schott JJ, et al. 1994 A radiation hybrid map of 506 STS markers spanning human chromosome 11. Nat Genet. 8:70-76.
19. Mochizuki H, Prochazka M. 1994 Dinucleotide repeat polymorphism at the PPP1CA locus on 11q13. Hum Mol Genet. 3:2265.
20. Burgess JR, Shepherd JJ, Parameswaran V, Hoffman L, Greenaway TM. 1996 Spectrum of pituitary disease in multiple endocrine neoplasia type 1 (MEN 1): clinical, biochemical, and radiological features of pituitary disease in a large MEN 1 kindred. J Clin Endocrinol Metab. 81:2642-2646.
21. Petty EM, Green JS, Marx SJ, Taggart RT, Farid N, Bale AE. 1994 Mapping the gene tor herditary hyperparathyroidism and prolactinoma (MEN 1 Burin) to chromosome 11q: evidence for a founder effect in patients from Newfoundland. Am J Hum Genet. 54:1060-1066.
22. Burgess JR, Shepherd JJ, Parameswaran V, Hoffman L, Greenaway TM. 1996 Prolactinomas in a large kindred with multiple endocrine neoplasia type 1: clinical features and inheritance pattern. J Clin Endocrinol Metab. 81:1841-1845.
23. Cadiot G, Laurent-Puig P, Thuille G, Lehy t, Mignon M, Olschwang S. 1993 Is the multiple endocrine neoplasia type 1 gene a suppressor for fundic argyrophil tumors in the Zollinger-Ellison syndrome. Gastroenterology. 105:579-582.
24. Teh BT, Hayward NK, Walters MK. 1994 Genetic studies of thymic carcinoids in multiple endocrine neoplasia type 1. J Med Genet. 31:261-262.
25. Jakobovitz O, Nass D, DeMarco L, et al. 1996 Carcinoid tumors frequently display genetic abnormalities involving chromosome 11. J Clin Endocrinol Metab. 81:3164-3167.
26. Morelli A, Falchetti A, Weinstein L, et al. 1995 RFLP analysis of human chromosome 11 region q13 in multiple symmetric lipomatosis and multiple endocrine neoplasia type 1-associated lipomas. Bioche Biophys Res Commun. 207:363-368.
27. Thakker RV, Pook MAP, Wooding C, Boscaro M, Scanarni M, Clayton RN. 1993 Association of somatotrophinomas with loss of alleles on chromosome 11 and with gsp mutations. J Clin Invest. 91:2815-2821.
28. Yoshimoto K, Iwahana H, Kubo K, Saito S, Itakura M. 1991 Allele loss on chromosome 11 in a pituitary tumor from a patient with multiple endocrine neoplasia type 1. Jpn J Cancer Res. 82:886-889.
29. Ilgren E, Westmoreland D. 1984 Tuberous sclerosis: unusual associations in four cases. J Clin Pathol. 37:272-278.
30. Colman SD, Williams CA, Wallace MR. 1995 Benign neurofibromas in type I neurofibromatosis (NFI) show somatic deletions in the NFI gene. Nat Genet. 11:90-92.
31. Sawada S, Florell S, Purandare SM, Ota M, Stephens K, Viskochil D. 1996 Identification of NFI mutations in both alleles of a dermal fibroma. Nat Gen. 14:110-112.
32. Henske EP, Scheithauer BW, Short MP, et al. 1996 Allelic loss is frequent in tuberous sclerosis kidney lesions but rare in brain lesions. Am J Hum Genet. 59:400-406.