Annexin A5 inhibits atherogenic and pro-inflammatory effects of lysophosphatidylcholine

Prostaglandins and Other Lipid Mediators

Volumn 106, Issue , 2013, Pages 72-78

  Domeij, Helena ^a   Hua, Xiang ^a   Su, Jun ^a   Bäcklund, Alexandra ^a   Yan, Zhongqun ^a   Frostegård, Anna G ^a   Haeggström, Jesper Z ^a   Modéer, Tomas ^a   Frostegård, Johan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Atherosclerosis; Inflammation; Leukotrienes; Lysophosphatidylcholine; Phospholipids

Indexed keywords

GELATINASE B; LEUKOTRIENE B4; LIPOCORTIN 5; LOW DENSITY LIPOPROTEIN; LYSOPHOSPHATIDYLCHOLINE; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VIVO STUDY; MACROPHAGE FUNCTION; MALE; MOUSE; NONHUMAN; PERITONEUM EXUDATE; PROTEIN EXPRESSION;

ATHEROSCLEROSIS; INFLAMMATION; LEUKOTRIENES; LYSOPHOSPHATIDYLCHOLINE; PHOSPHOLIPIDS;

ANIMALS; ANNEXIN A5; BIOLOGICAL TRANSPORT; CELL LINE; CELL MOVEMENT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; LEUKOTRIENE B4; LIPOPROTEINS, LDL; LYSOPHOSPHATIDYLCHOLINES; MACROPHAGES; MATRIX METALLOPROTEINASE 9; MICE; PLAQUE, ATHEROSCLEROTIC;

EID: 84888874398     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2013.01.004     Document Type: Article

References (43)

1. J. Frostegard, A.K. Ulfgren, P. Nyberg, U. Hedin, J. Swedenborg, and U. Andersson Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines Atherosclerosis 145 1 1999 33 43 (Pubitemid 29292698)
2. C.M. Dollery, and P. Libby Atherosclerosis and proteinase activation Cardiovasc Res 69 3 2006 625 635 (Pubitemid 43139725)
3. H. Qiu, A. Gabrielsen, H.E. Agardh, M. Wan, A. Wetterholm, and C.H. Wong Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability Proc Natl Acad Sci USA 103 21 2006 8161 8166 (Pubitemid 43801069)
4. J.Z. Haeggstrom, and C.D. Funk Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease Chem Rev 111 10 2011 5866 5898
5. C.J. Binder, M.K. Chang, P.X. Shaw, Y.I. Miller, K. Hartvigsen, and A. Dewan Innate and acquired immunity in atherogenesis Nat Med 8 11 2002 1218 1226 (Pubitemid 35373552)
6. P. Libby, P.M. Ridker, and A. Maseri Inflammation and atherosclerosis Circulation 105 9 2002 1135 1143 (Pubitemid 34212626)
7. J.A. Berliner, M.C. Territo, A. Sevanian, S. Ramin, J.A. Kim, and B. Bamshad Minimally modified low density lipoprotein stimulates monocyte endothelial interactions J Clin Invest 85 4 1990 1260 1266 (Pubitemid 20123772)
8. J. Frostegard, A. Haegerstrand, M. Gidlund, and J. Nilsson Biologically modified LDL increases the adhesive properties of endothelial cells Atherosclerosis 90 2-3 1991 119 126
9. J. Frostegard, J. Nilsson, A. Haegerstrand, A. Hamsten, H. Wigzell, and M. Gidlund Oxidized low density lipoprotein induces differentiation and adhesion of human monocytes and the monocytic cell line U937 Proc Natl Acad Sci USA 87 3 1990 904 908
10. J. Frostegard, R. Wu, R. Giscombe, G. Holm, A.K. Lefvert, and J. Nilsson Induction of T-cell activation by oxidized low density lipoprotein Arterioscler Thromb 12 4 1992 461 467
11. M.T. Quinn, S. Parthasarathy, and D. Steinberg Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis Proc Natl Acad Sci USA 85 8 1988 2805 2809
12. Y.H. Huang, L. Schafer-Elinder, R. Wu, H.E. Claesson, and J. Frostegard Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet-activating factor (PAF) receptor-dependent mechanism Clin Exp Immunol 116 2 1999 326 331 (Pubitemid 29219732)
13. J. Frostegard, Y.H. Huang, J. Ronnelid, and L. Schafer-Elinder Platelet-activating factor and oxidized LDL induce immune activation by a common mechanism Arterioscler Thromb Vasc Biol 17 5 1997 963 968 (Pubitemid 27209276)
14. A. Cederholm, and J. Frostegard Annexin A5 in cardiovascular disease and systemic lupus erythematosus Immunobiology 210 10 2005 761 768 (Pubitemid 41683860)
15. A. Cederholm, E. Svenungsson, K. Jensen-Urstad, C. Trollmo, A.K. Ulfgren, and J. Swedenborg Decreased binding of Annexin V to endothelial cells: a potential mechanism in atherothrombosis of patients with systemic lupus erythematosus Arterioscler Thromb Vasc Biol 25 1 2005 198 203 (Pubitemid 40054276)
16. A. Frostegard, J. Su, P. von Landenberg, and J. Frostegard Effects of anti-cardiolipin antibodies and IVIg on annexin A5 binding to endothelial cells: implications for cardiovascular disease Scand J Rheumatol 39 1 2010 77 83
17. M.M. Ewing, M.R. de Vries, M. Nordzell, K. Pettersson, H.C. de Boer, and A.J. van Zonneveld Annexin A5 therapy attenuates vascular inflammation and remodeling and improves endothelial function in mice Arterioscler Thromb Vasc Biol 31 1 2010 95 101
18. P.J. Gough, I.G. Gomez, P.T. Wille, and E.W. Raines Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice J Clin Invest 116 1 2006 59 69 (Pubitemid 43121791)
19. J.O. Deguchi, M. Aikawa, C.H. Tung, E. Aikawa, D.E. Kim, and V. Ntziachristos Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo Circulation 114 1 2006 55 62 (Pubitemid 44305275)
20. H. Domeij, T. Yucel-Lindberg, and T. Modeer Cell interactions between human gingival fibroblasts and monocytes stimulate the production of matrix metalloproteinase-1 in gingival fibroblasts J Periodontal Res 41 2 2006 108 117 (Pubitemid 43341283)
21. X.P. Xu, S.R. Meisel, J.M. Ong, S. Kaul, B. Cercek, and T.B. Rajavashisth Oxidized low-density lipoprotein regulates matrix metalloproteinase-9 and its tissue inhibitor in human monocyte-derived macrophages Circulation 99 8 1999 993 998 (Pubitemid 29104486)
22. P. Thiagarajan, and C.R. Benedict Inhibition of arterial thrombosis by recombinant Annexin V in a rabbit carotid artery injury model Circulation 96 7 1997 2339 2347 (Pubitemid 27425842)
23. H. Ishii, M. Hiraoka, A. Tanaka, K. Shimokado, and M. Yoshida Recombinant Annexin-2 inhibits the progress of diabetic nephropathy in a diabetic mouse model via recovery of hypercoagulability Thromb Haemost 97 1 2007 124 128 (Pubitemid 46242393)
24. S. Ding, M. Zhang, Y. Zhao, W. Chen, G. Yao, and C. Zhang The role of carotid plaque vulnerability and inflammation in the pathogenesis of acute ischemic stroke Am J Med Sci 336 1 2008 27 31
25. P. Welsh, P.H. Whincup, O. Papacosta, S.G. Wannamethee, L. Lennon, and A. Thomson Serum matrix metalloproteinase-9 and coronary heart disease: a prospective study in middle-aged men Q J Med 101 10 2008 785 791
26. Y.S. Hamirani, S. Pandey, J.J. Rivera, C. Ndumele, M.J. Budoff, and R.S. Blumenthal Markers of inflammation and coronary artery calcification: a systematic review Atherosclerosis 201 1 2008 1 7
27. R.R. Packard, and P. Libby Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction Clin Chem 54 1 2008 24 38 (Pubitemid 351182593)
28. A. Ducharme, S. Frantz, M. Aikawa, E. Rabkin, M. Lindsey, and L.E. Rohde Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction J Clin Invest 106 1 2000 55 62 (Pubitemid 30437240)
29. S. Heymans, A. Luttun, D. Nuyens, G. Theilmeier, E. Creemers, and L. Moons Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure Nat Med 5 10 1999 1135 1142 (Pubitemid 29474417)
30. C.H. Serezani, D.M. Aronoff, S. Jancar, P. Mancuso, and M. Peters-Golden Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase Blood 106 3 2005 1067 1075 (Pubitemid 41076456)
31. M. Wan, A. Sabirsh, A. Wetterholm, B. Agerberth, and J.Z. Haeggstrom Leukotriene B4 triggers release of the cathelicidin LL-37 from human neutrophils: novel lipid-peptide interactions in innate immune responses FASEB J 21 11 2007 2897 2905 (Pubitemid 47372756)
32. K. Goodarzi, M. Goodarzi, A.M. Tager, A.D. Luster, and U.H. von Andrian Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues Nat Immunol 4 10 2003 965 973 (Pubitemid 37265917)
33. C.D. Funk Leukotriene modifiers as potential therapeutics for cardiovascular disease Nat Rev Drug Discov 4 8 2005 664 672 (Pubitemid 41149760)
34. A. Helgadottir, A. Manolescu, A. Helgason, G. Thorleifsson, U. Thorsteinsdottir, and D.F. Gudbjartsson A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction Nat Genet 38 1 2006 68 74 (Pubitemid 43011884)
35. A. Helgadottir, A. Manolescu, G. Thorleifsson, S. Gretarsdottir, H. Jonsdottir, and U. Thorsteinsdottir The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke Nat Genet 36 3 2004 233 239 (Pubitemid 38282747)
36. J.H. Dwyer, H. Allayee, K.M. Dwyer, J. Fan, H. Wu, and R. Mar Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis N Engl J Med 350 1 2004 29 37 (Pubitemid 38032181)
37. R. Spanbroek, R. Grabner, K. Lotzer, M. Hildner, A. Urbach, and K. Ruhling Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis Proc Natl Acad Sci USA 100 3 2003 1238 1243 (Pubitemid 36183986)
38. T. Itou, L.V. Collins, F.B. Thoren, C. Dahlgren, and A. Karlsson Changes in activation states of murine polymorphonuclear leukocytes (PMN) during inflammation: a comparison of bone marrow and peritoneal exudate PMN Clin Vaccine Immunol 13 5 2006 575 583 (Pubitemid 43736459)
39. M. Dashti, W. Kulik, F. Hoek, E.C. Veerman, M.P. Peppelenbosch, and F. Rezaee A phospholipidomic analysis of all defined human plasma lipoproteins Sci Rep 1 2012 139
40. J.H. Rand, X.X. Wu, A.S. Quinn, P.P. Chen, K.R. McCrae, and E.G. Bovill Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: evidence from atomic force microscopy and functional assay Am J Pathol 163 3 2003 1193 1200 (Pubitemid 37040155)
41. U. de Faire, J. Su, X. Hua, A. Frostegard, M. Halldin, and M.L. Hellenius Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: effects on uptake of oxidized LDL in macrophages as a potential mechanism J Autoimmun 34 2 2010 73 79
42. S. Xu, Y. Huang, Y. Xie, T. Lan, K. Le, and J. Chen Evaluation of foam cell formation in cultured macrophages: an improved method with Oil Red O staining and DiI-OxLDL uptake Cytotechnology 62 5 2010 473 481
43. M. Febbraio, E.A. Podrez, J.D. Smith, D.P. Hajjar, S.L. Hazen, and H.F. Hoff Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice J Clin Invest 105 8 2000 1049 1056 (Pubitemid 30217689)