Protective effect of statin therapy on connective tissue growth factor induction by diabetes in vivo and high glucose in vitro

Growth Factors

Volumn 31, Issue 6, 2013, Pages 199-208

  Yang, Bingmei ^a   Hodgkinson, Andrea D ^a   Shaw, Nicholas A ^a   Millward, Beverley A ^a   Demaine, Andrew G ^a  

^a PLYMOUTH UNIVERSITY PENINSULA SCHOOLS OF MEDICINE AND DENTISTRY   (United Kingdom)

Author keywords

Connective tissue growth factor; Diabetes; Diabetic nephropathy; High glucose; Statins

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LUCIFERASE; SIMVASTATIN; TUBULIN; BIOLOGICAL MARKER; RENILLA LUCIFERIN 2 MONOOXYGENASE;

AGED; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MACROALBUMINURIA; MAJOR CLINICAL STUDY; MALE; MESANGIUM CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN URINE LEVEL; RENAL PROTECTION; ALBUMINURIA; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; MESANGIUM; METABOLISM; TRANSFORMED CELL LINE; URINE;

ALBUMINURIA; BIOLOGICAL MARKERS; CELL LINE, TRANSFORMED; CONNECTIVE TISSUE GROWTH FACTOR; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; GENE EXPRESSION REGULATION; GLOMERULAR MESANGIUM; GLUCOSE; HEK293 CELLS; HUMANS; LUCIFERASES, RENILLA; PROMOTER REGIONS, GENETIC; SIMVASTATIN; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 84888861312     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.3109/08977194.2013.852189     Document Type: Article

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