Synthesis and evaluation of two coumarin-type derivatization reagents for fluorescence detection of chiral amines and chiral carboxylic acids

Chirality

Volumn 25, Issue 12, 2013, Pages 957-964

  Mertens, Matthias D ^a   Gütschow, Michael ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

chiral coumarins; diastereomer separation; fluorescence detection; Mitsunobu reaction; precolumn derivatization; reversed phase high performance liquid chromatography

Indexed keywords

AMINE; CARBON; CARBOXYLIC ACID; COUMARIN; DEXTRO 2[3(4 METHOXYPHENYL) 2 OXO 2 CHROMEN 7 YLOXY] PROPANOIC; FLURBIPROFEN; IBUPROFEN; KETOPROFEN; LEVO 1[3 (METHOXYCARBONYL) 2 OXO 2H CHROMONE 7 YLOXY) PROPAN 2 AMINIUM CHLORIDE; PROPIONIC ACID; REAGENT; UNCLASSIFIED DRUG; COUMARIN DERIVATIVE; FLUORESCENT DYE; PROPIONIC ACID DERIVATIVE;

ARTICLE; CHIRALITY; DERIVATIZATION; DRUG CONJUGATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORESCENCE; PRIORITY JOURNAL; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STEREOISOMERISM; SYNTHESIS;

AMINES; CARBOXYLIC ACIDS; CHEMISTRY TECHNIQUES, ANALYTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARINS; FLUORESCENT DYES; MOLECULAR STRUCTURE; PROPIONATES; STEREOISOMERISM;

EID: 84888860407     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.22240     Document Type: Article

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