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Volumn 65, Issue 15, 2013, Pages 2111-2119

Pharmacology of carbon nanotubes: Toxicokinetics, excretion and tissue accumulation

Author keywords

Biodistribution; Carbon nanotubes; CNT; Functionalisation; Nanotoxicology; Toxicokinetics

Indexed keywords

BIODISTRIBUTIONS; CNT; FUNCTIONALISATION; NANOTOXICOLOGY; TOXICOKINETICS;

EID: 84888860279     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2013.10.004     Document Type: Review
Times cited : (84)

References (60)
  • 2
    • 14544277499 scopus 로고    scopus 로고
    • Biomedical applications of functionalised carbon nanotubes
    • Bianco A., Kostarelos K., Partidos C.D., Prato M. Biomedical applications of functionalised carbon nanotubes. Chem. Commun. 2005, 5:571-577.
    • (2005) Chem. Commun. , vol.5 , pp. 571-577
    • Bianco, A.1    Kostarelos, K.2    Partidos, C.D.3    Prato, M.4
  • 4
    • 77957137765 scopus 로고    scopus 로고
    • Carbon nanotubes: fibrillar pharmacology
    • Kostarelos K. Carbon nanotubes: fibrillar pharmacology. Nat. Mater. 2010, 9:793-795.
    • (2010) Nat. Mater. , vol.9 , pp. 793-795
    • Kostarelos, K.1
  • 5
    • 70350662339 scopus 로고    scopus 로고
    • Promises, facts and challenges for carbon nanotubes in imaging and therapeutics
    • Kostarelos K., Bianco A., Prato M. Promises, facts and challenges for carbon nanotubes in imaging and therapeutics. Nat. Nanotechnol. 2009, 4:627-633.
    • (2009) Nat. Nanotechnol. , vol.4 , pp. 627-633
    • Kostarelos, K.1    Bianco, A.2    Prato, M.3
  • 6
    • 67649890883 scopus 로고    scopus 로고
    • Antitumor activity and prolonged survival by carbon-nanotube-mediated therapeutic siRNA silencing in a human lung xenograft model
    • Podesta J., Al-Jamal T.K., Herrero M.A., Tian B., Ali-Boucetta H., Hegde V., Bianco A., Prato M., Kostarelos K. Antitumor activity and prolonged survival by carbon-nanotube-mediated therapeutic siRNA silencing in a human lung xenograft model. Small 2009, 1176-1185.
    • (2009) Small , pp. 1176-1185
    • Podesta, J.1    Al-Jamal, T.K.2    Herrero, M.A.3    Tian, B.4    Ali-Boucetta, H.5    Hegde, V.6    Bianco, A.7    Prato, M.8    Kostarelos, K.9
  • 7
    • 49749128832 scopus 로고    scopus 로고
    • Carbon-nanotube shape and individualization critical for renal excretion
    • Lacerda L., Herrero M.A., Venner K., Bianco A., Prato M., Kostarelos K. Carbon-nanotube shape and individualization critical for renal excretion. Small 2008, 4:1130-1132.
    • (2008) Small , vol.4 , pp. 1130-1132
    • Lacerda, L.1    Herrero, M.A.2    Venner, K.3    Bianco, A.4    Prato, M.5    Kostarelos, K.6
  • 11
    • 40349112868 scopus 로고    scopus 로고
    • Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy
    • Liu Z., Davis C., Cai W., He L., Chen X., Dai H. Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:1410-1415.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 1410-1415
    • Liu, Z.1    Davis, C.2    Cai, W.3    He, L.4    Chen, X.5    Dai, H.6
  • 12
    • 84876043106 scopus 로고    scopus 로고
    • Thermostable luciferase from Luciola cruciate for imaging of carbon nanotubes and carbon nanotubes carrying doxorubicin using in vivo imaging system
    • El-Sayed R., Eita M., Barrefelt Å., Ye F., Jain H., Fares M., Lundin A., Crona M., Abu-Salah K., Muhammed M., Hassan M. Thermostable luciferase from Luciola cruciate for imaging of carbon nanotubes and carbon nanotubes carrying doxorubicin using in vivo imaging system. Nano Lett. 2013, 13:1393-1398.
    • (2013) Nano Lett. , vol.13 , pp. 1393-1398
    • El-Sayed, R.1    Eita, M.2    Barrefelt, Å.3    Ye, F.4    Jain, H.5    Fares, M.6    Lundin, A.7    Crona, M.8    Abu-Salah, K.9    Muhammed, M.10    Hassan, M.11
  • 13
    • 80052552513 scopus 로고    scopus 로고
    • Making carbon nanotubes biocompatible and biodegradable
    • Bianco A., Kostarelos K., Prato M. Making carbon nanotubes biocompatible and biodegradable. Chem. Commun. 2011, 47.
    • (2011) Chem. Commun. , vol.47
    • Bianco, A.1    Kostarelos, K.2    Prato, M.3
  • 15
    • 23844531202 scopus 로고    scopus 로고
    • Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction
    • Kam N.W.S., O'Connell M., Wisdom J.A., Dai H. Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:11600-11605.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 11600-11605
    • Kam, N.W.S.1    O'Connell, M.2    Wisdom, J.A.3    Dai, H.4
  • 18
    • 33846845060 scopus 로고    scopus 로고
    • In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice
    • Liu Z., Cai W., He L., Nakayama N., Chen K., Sun X., Chen X., Dai H. In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat. Nanotechnol. 2007, 2:47-52.
    • (2007) Nat. Nanotechnol. , vol.2 , pp. 47-52
    • Liu, Z.1    Cai, W.2    He, L.3    Nakayama, N.4    Chen, K.5    Sun, X.6    Chen, X.7    Dai, H.8
  • 20
    • 78349304285 scopus 로고    scopus 로고
    • Optimization of surface chemistry on single-walled carbon nanotubes for in vivo photothermal ablation of tumors
    • Liu X., Tao H., Yang K., Zhang S., Lee S.-T., Liu Z. Optimization of surface chemistry on single-walled carbon nanotubes for in vivo photothermal ablation of tumors. Biomaterials 2011, 32:144-151.
    • (2011) Biomaterials , vol.32 , pp. 144-151
    • Liu, X.1    Tao, H.2    Yang, K.3    Zhang, S.4    Lee, S.-T.5    Liu, Z.6
  • 22
    • 34250702267 scopus 로고    scopus 로고
    • Biodistribution of functionalized multiwall carbon nanotubes in mice
    • Guo J., Zhang X., Li Q., Li W. Biodistribution of functionalized multiwall carbon nanotubes in mice. Nucl. Med. Biol. 2007, 34:579-583.
    • (2007) Nucl. Med. Biol. , vol.34 , pp. 579-583
    • Guo, J.1    Zhang, X.2    Li, Q.3    Li, W.4
  • 24
    • 34249663107 scopus 로고    scopus 로고
    • Translocation and fate of multi-walled carbon nanotubes in vivo
    • Deng X., Jia G., Wang H., Sun H., Wang X., Yang S., Wang T., Liu Y. Translocation and fate of multi-walled carbon nanotubes in vivo. Carbon 2007, 45:1419-1424.
    • (2007) Carbon , vol.45 , pp. 1419-1424
    • Deng, X.1    Jia, G.2    Wang, H.3    Sun, H.4    Wang, X.5    Yang, S.6    Wang, T.7    Liu, Y.8
  • 25
    • 64749117000 scopus 로고    scopus 로고
    • Rapid translocation and pharmacokinetics of hydroxylated single-walled carbon nanotubes in mice
    • Wang J., Deng X., Yang S., Wang H., Zhao Y., Liu Y. Rapid translocation and pharmacokinetics of hydroxylated single-walled carbon nanotubes in mice. Nanotoxicology 2008, 2:28-32.
    • (2008) Nanotoxicology , vol.2 , pp. 28-32
    • Wang, J.1    Deng, X.2    Yang, S.3    Wang, H.4    Zhao, Y.5    Liu, Y.6
  • 26
    • 38949174620 scopus 로고    scopus 로고
    • A generally adoptable radiotracing method for tracking carbon nanotubes in animals
    • Deng X., Yang S., Nie H., Wang H., Liu Y. A generally adoptable radiotracing method for tracking carbon nanotubes in animals. Nanotechnology 2008, 19:075101.
    • (2008) Nanotechnology , vol.19 , pp. 075101
    • Deng, X.1    Yang, S.2    Nie, H.3    Wang, H.4    Liu, Y.5
  • 29
    • 42949094111 scopus 로고    scopus 로고
    • Tissue histology and physiology following intravenous administration of different types of functionalized multiwalled carbon nanotubes
    • Lacerda L., Ali-Boucetta H., Herrero M.A., Pastorin G., Bianco A., Prato M., Kostarelos K. Tissue histology and physiology following intravenous administration of different types of functionalized multiwalled carbon nanotubes. Nanomedicine 2008, 3:149-161.
    • (2008) Nanomedicine , vol.3 , pp. 149-161
    • Lacerda, L.1    Ali-Boucetta, H.2    Herrero, M.A.3    Pastorin, G.4    Bianco, A.5    Prato, M.6    Kostarelos, K.7
  • 31
    • 81755175673 scopus 로고    scopus 로고
    • Toxicity of multiwalled carbon nanotubes with end defects critically depends on their functionalization density
    • Jain S., Thakare V.S., Das M., Godugu C., Jain A.K., Mathur R., Chuttani K., Mishra A.K. Toxicity of multiwalled carbon nanotubes with end defects critically depends on their functionalization density. Chem. Res. Toxicol. 2011, 24:2028-2039.
    • (2011) Chem. Res. Toxicol. , vol.24 , pp. 2028-2039
    • Jain, S.1    Thakare, V.S.2    Das, M.3    Godugu, C.4    Jain, A.K.5    Mathur, R.6    Chuttani, K.7    Mishra, A.K.8
  • 33
    • 53049104252 scopus 로고    scopus 로고
    • Drug delivery with carbon nanotubes for in vivo cancer treatment
    • Liu Z., Chen K., Davis C., Sherlock S., Cao Q., Chen X., Dai H. Drug delivery with carbon nanotubes for in vivo cancer treatment. Cancer Res. 2008, 68:6652-6660.
    • (2008) Cancer Res. , vol.68 , pp. 6652-6660
    • Liu, Z.1    Chen, K.2    Davis, C.3    Sherlock, S.4    Cao, Q.5    Chen, X.6    Dai, H.7
  • 34
    • 36849063744 scopus 로고    scopus 로고
    • Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery
    • Liu Z., Sun X., Nakayama-Ratchford N., Dai H. Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery. ACS Nano 2007, 1:50-56.
    • (2007) ACS Nano , vol.1 , pp. 50-56
    • Liu, Z.1    Sun, X.2    Nakayama-Ratchford, N.3    Dai, H.4
  • 36
    • 77954752427 scopus 로고    scopus 로고
    • Long-term hepatotoxicity of polyethylene-glycol functionalized multi-walled carbon nanotubes in mice
    • Zhang D., Deng X., Ji Z., Shen X., Dong L., Wu M., Gu T., Liu Y. Long-term hepatotoxicity of polyethylene-glycol functionalized multi-walled carbon nanotubes in mice. Nanotechnology 2010, 21:1-10.
    • (2010) Nanotechnology , vol.21 , pp. 1-10
    • Zhang, D.1    Deng, X.2    Ji, Z.3    Shen, X.4    Dong, L.5    Wu, M.6    Gu, T.7    Liu, Y.8
  • 37
    • 84876296355 scopus 로고    scopus 로고
    • Biodistribution of multi-walled carbon nanotubes functionalized by hydroxyl terminated poly(ethylene glycol) in mice
    • Yang S.-T., Wang Y.-W., Liu J.-H., Wang H. Biodistribution of multi-walled carbon nanotubes functionalized by hydroxyl terminated poly(ethylene glycol) in mice. J. Radioanal. Nucl. Chem. 2013, 295:1181-1186.
    • (2013) J. Radioanal. Nucl. Chem. , vol.295 , pp. 1181-1186
    • Yang, S.-T.1    Wang, Y.-W.2    Liu, J.-H.3    Wang, H.4
  • 39
    • 73349127843 scopus 로고    scopus 로고
    • Control of the in vivo biodistribution of hybrid nanoparticles with different poly(ethylene glycol) coatings
    • Faure A.-C., Dufort S., Josserand V., Perriat P., Coll J.-L., Roux S., Tillement O. Control of the in vivo biodistribution of hybrid nanoparticles with different poly(ethylene glycol) coatings. Small 2009, 5:2565-2575.
    • (2009) Small , vol.5 , pp. 2565-2575
    • Faure, A.-C.1    Dufort, S.2    Josserand, V.3    Perriat, P.4    Coll, J.-L.5    Roux, S.6    Tillement, O.7
  • 46
    • 52049100604 scopus 로고    scopus 로고
    • Long-term accumulation and low toxicity of single-walled carbon nanotubes in intravenously exposed mice
    • Yang S.T., Wang X., Jia G., Gu Y., Wang T., Nie H., Ge C., Wang H., Liu Y. Long-term accumulation and low toxicity of single-walled carbon nanotubes in intravenously exposed mice. Toxicol. Lett. 2008, 181:182-189.
    • (2008) Toxicol. Lett. , vol.181 , pp. 182-189
    • Yang, S.T.1    Wang, X.2    Jia, G.3    Gu, Y.4    Wang, T.5    Nie, H.6    Ge, C.7    Wang, H.8    Liu, Y.9
  • 47
    • 62949149463 scopus 로고    scopus 로고
    • The splenic toxicity of water soluble multi-walled carbon nanotubes in mice
    • Deng X., Wu F., Liu Z., Luo M., Li L., Ni Q., Jiao Z., Wu M., Liu Y. The splenic toxicity of water soluble multi-walled carbon nanotubes in mice. Carbon 2009, 47:1421-1428.
    • (2009) Carbon , vol.47 , pp. 1421-1428
    • Deng, X.1    Wu, F.2    Liu, Z.3    Luo, M.4    Li, L.5    Ni, Q.6    Jiao, Z.7    Wu, M.8    Liu, Y.9
  • 48
    • 1642503815 scopus 로고    scopus 로고
    • Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
    • Maynard A.D., Baron P.A., Foley M., Shvedova A.A., Kisin E.R., Castranova V. Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material. J. Toxicol. Environ. Health A 2004, 67:87-107.
    • (2004) J. Toxicol. Environ. Health A , vol.67 , pp. 87-107
    • Maynard, A.D.1    Baron, P.A.2    Foley, M.3    Shvedova, A.A.4    Kisin, E.R.5    Castranova, V.6
  • 49
    • 34547206282 scopus 로고    scopus 로고
    • Comparative study of pathological lesions induced by multiwalled carbon nanotubes in lungs of mice by intratracheal instillation and inhalation
    • Li J.G., Li W.X., Xu J.Y., Cai X.Q., Liu R.L., Li Y.J., Zhao Q.F., Li Q.N. Comparative study of pathological lesions induced by multiwalled carbon nanotubes in lungs of mice by intratracheal instillation and inhalation. Environ. Toxicol. 2007, 22:415-421.
    • (2007) Environ. Toxicol. , vol.22 , pp. 415-421
    • Li, J.G.1    Li, W.X.2    Xu, J.Y.3    Cai, X.Q.4    Liu, R.L.5    Li, Y.J.6    Zhao, Q.F.7    Li, Q.N.8
  • 51
    • 67651227154 scopus 로고    scopus 로고
    • Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice
    • Mitchell L.A., Lauer F.T., Burchiel S.W., McDonald J.D. Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice. Nat. Nanotechnol. 2009, 4:451-456.
    • (2009) Nat. Nanotechnol. , vol.4 , pp. 451-456
    • Mitchell, L.A.1    Lauer, F.T.2    Burchiel, S.W.3    McDonald, J.D.4
  • 53
    • 1542726626 scopus 로고    scopus 로고
    • Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90days after intratracheal instillation
    • Lam C.W., James J.T., McCluskey R., Hunter R.L. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90days after intratracheal instillation. Toxicol. Sci. 2004, 77:126-134.
    • (2004) Toxicol. Sci. , vol.77 , pp. 126-134
    • Lam, C.W.1    James, J.T.2    McCluskey, R.3    Hunter, R.L.4
  • 56
    • 55049105672 scopus 로고    scopus 로고
    • Induction of apoptosis and absence of inflammation in rat lung after intratracheal instillation of multiwalled carbon nanotubes
    • Elgrabli D., Abella-Gallart S., Robidel F., Rogerieux F., Boczkowski J., Lacroix G. Induction of apoptosis and absence of inflammation in rat lung after intratracheal instillation of multiwalled carbon nanotubes. Toxicology 2008, 253:131-136.
    • (2008) Toxicology , vol.253 , pp. 131-136
    • Elgrabli, D.1    Abella-Gallart, S.2    Robidel, F.3    Rogerieux, F.4    Boczkowski, J.5    Lacroix, G.6
  • 59
    • 0034924432 scopus 로고    scopus 로고
    • Carbon nanotubes: experimental evidence for a null risk of skin irritation and allergy
    • Huczko A., Lange H. Carbon nanotubes: experimental evidence for a null risk of skin irritation and allergy. Fuller. Sci. Technol. 2001, 9:247-250.
    • (2001) Fuller. Sci. Technol. , vol.9 , pp. 247-250
    • Huczko, A.1    Lange, H.2
  • 60
    • 84863469843 scopus 로고    scopus 로고
    • In vivo fluorescence imaging in the second near-infrared window with long circulating carbon nanotubes capable of ultrahigh tumor uptake
    • Robinson J.T., Hong G., Liang Y., Zhang B., Yaghi O.K., Dai H. In vivo fluorescence imaging in the second near-infrared window with long circulating carbon nanotubes capable of ultrahigh tumor uptake. J. Am. Chem. Soc. 2012, 134:10664-10669.
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 10664-10669
    • Robinson, J.T.1    Hong, G.2    Liang, Y.3    Zhang, B.4    Yaghi, O.K.5    Dai, H.6


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